EKS-TAG-00213

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00213

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Ryk	486.2	2.0E-146	201	467	267

Status

Unreviewed

Ensembl Protein

ENSTGUP00000006862

UniProt Accession

H0Z8F9;

Protein Name

Protein Synonyms/Alias

Gene Name

RYK

Gene Synonyms/Alias

RYK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000006671	ENSTGUP00000006862	ENSTGUT00000006931

Organism

Taeniopygia guttata

Functional Description

Protein Length

478

Protein Sequence
(FASTA)

MAMALPQANI SLQGEVPRTL SVFRVELSCT GRLDSDVTIL MQLNLTINSS KNITVLNFKR 60

RKMCYKKLEP EVKSPTADRN SSKAIFDPVN AAPTTSTRVF YISVGVCCAV IFLVAIILAV 120

LHLHSMKRIE LDDSISDSSS SQGLSQPSTQ TTQYLRADTP NNATPVTSYP TLRIEKNDLK 180

SVTLMEAKAK VKDIAISRER ITLKDVLQEG TFGRIFHGIL IEEKDPSKEK QVFVKTVKDQ 240

ASEVQVTMML TESCKLRGLH HRNLLPITHV CIEEGEKPMV LLPYMNWGNL KLFLRQCKLV 300

EANNPQAISQ QDLVHMAIQI ACGMSYLARR EVIHKDLAAR NCVIDDGLQV KITDNALSRD 360

LFPMDYHCLG DNENRPVRWM ALESLVNNDF SSASDVWAFG VTLWELMTLG QTPYVDIDPF 420

EMAAYLKDGY RIAQPINCPD ELFAVMACCW ALDPEERPKF QQLVQCLTEF HAALGAYV 478

Nucleotide Sequence
(FASTA)

ATGGCTATGG CCTTGCCCCA GGCCAACATT TCTCTACAAG GAGAAGTTCC TCGCACCCTC 60

TCAGTGTTCC GTGTCGAACT CTCCTGCACC GGCAGACTCG ACTCCGATGT CACAATCCTG 120

ATGCAGCTCA ACTTAACAAT AAATTCCTCA AAAAACATCA CAGTTTTAAA TTTCAAACGA 180

AGGAAAATGT GCTACAAAAA GCTTGAACCA GAAGTCAAAT CTCCAACAGC TGATAGAAAC 240

AGCAGCAAGG CTATCTTCGA TCCTGTAAAT GCAGCTCCCA CCACTTCGAC CCGTGTGTTC 300

TATATCAGTG TGGGTGTGTG CTGTGCTGTG ATATTCCTGG TGGCAATAAT CCTGGCTGTC 360

TTGCACCTCC ACAGCATGAA AAGGATAGAG TTGGATGACA GCATCAGCGA CAGCAGCAGC 420

TCGCAGGGGC TGTCGCAGCC CTCCACGCAG ACGACGCAGT ACCTGCGGGC TGACACGCCC 480

AACAATGCCA CGCCAGTAAC CAGTTATCCC ACATTACGGA TAGAGAAGAA TGATCTGAAA 540

AGTGTCACTC TTATGGAGGC TAAAGCTAAA GTGAAGGACA TAGCCATCTC CAGGGAGAGG 600

ATCACCCTCA AAGACGTGCT CCAAGAAGGC ACGTTTGGGC GCATTTTCCA TGGAATTCTA 660

ATAGAAGAAA AAGACCCCAG TAAAGAGAAA CAAGTTTTTG TCAAAACTGT TAAAGATCAA 720

GCCTCAGAGG TGCAGGTGAC AATGATGCTG ACGGAAAGCT GTAAACTCAG AGGGCTTCAC 780

CACAGGAATC TGCTGCCTAT CACTCATGTC TGTATAGAGG AGGGAGAGAA ACCAATGGTG 840

CTGCTGCCCT ACATGAACTG GGGGAACCTT AAACTCTTCC TGCGACAGTG CAAGTTGGTG 900

GAGGCCAACA ATCCCCAGGC GATTTCCCAG CAGGATCTGG TACACATGGC CATCCAGATT 960

GCCTGTGGGA TGAGCTACCT GGCCAGGAGG GAGGTCATCC ACAAAGACCT GGCTGCAAGG 1020

AACTGTGTCA TCGACGACGG CCTGCAGGTG AAGATCACGG ACAACGCGCT GTCACGAGAC 1080

CTGTTCCCCA TGGACTACCA CTGCCTGGGG GACAACGAGA ACAGACCAGT CCGCTGGATG 1140

GCTCTGGAAA GCCTGGTCAA CAATGATTTT TCCAGTGCTA GTGATGTGTG GGCCTTCGGG 1200

GTGACGCTGT GGGAGCTGAT GACCCTGGGA CAGACCCCCT ACGTGGACAT CGACCCCTTT 1260

GAGATGGCAG CTTATTTAAA GGATGGTTAT CGAATAGCTC AGCCCATCAA CTGCCCCGAT 1320

GAACTGTTTG CTGTGATGGC CTGCTGCTGG GCCCTAGATC CTGAGGAGAG ACCCAAGTTT 1380

CAGCAGCTGG TGCAATGTCT CACTGAATTT CACGCAGCAT TGGGAGCCTA CGTC 1434

Domain Profile

S: 1     lrlkellqeGtfGriyrGkledekdtnkekavlvktvkdqaseiqvalllqealllygvs  60

         ++lk++lqeGtfGri++G+l +ekd++kek+v+vktvkdqase+qv+++l+e+++l+g++

Q: 201   ITLKDVLQEGTFGRIFHGILIEEKDPSKEKQVFVKTVKDQASEVQVTMMLTESCKLRGLH  260

         6799********************************************************

S: 61    hrnilsvllvsieeaekPlvvypalnkgnlkkflricklkdkekaqalstkqlvelaiqi  120

         hrn+l++++v+iee ekP+v++p++n+gnlk flr+ckl++++++qa+s+++lv++aiqi

Q: 261   HRNLLPITHVCIEEGEKPMVLLPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQI  320

         ************************************************************

S: 121   asalaylhkrevvhkdiaarncviddelqvkltdsalsrdlfPadydclGdnenrPlkWl  180

         a++++yl++rev+hkd+aarncvidd lqvk+td+alsrdlfP+dy+clGdnenrP++W+

Q: 321   ACGMSYLARREVIHKDLAARNCVIDDGLQVKITDNALSRDLFPMDYHCLGDNENRPVRWM  380

         ************************************************************

S: 181   slealqkeeyssasdvWalGvllWelvtlgksPyaeidpfeleaylkdGyrlaqPvncPd  240

         +le+l+++ +ssasdvWa+Gv+lWel+tlg++Py++idpfe++aylkdGyr+aqP+ncPd

Q: 381   ALESLVNNDFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPD  440

         ************************************************************

S: 241   elftvmaccWallpeerPsfeqlvscl  267

         elf+vmaccWal+peerP+f+qlv+cl

Q: 441   ELFAVMACCWALDPEERPKFQQLVQCL  467

         **************************8

Domain Sequence
(FASTA)

ITLKDVLQEG TFGRIFHGIL IEEKDPSKEK QVFVKTVKDQ ASEVQVTMML TESCKLRGLH 60

HRNLLPITHV CIEEGEKPMV LLPYMNWGNL KLFLRQCKLV EANNPQAISQ QDLVHMAIQI 120

ACGMSYLARR EVIHKDLAAR NCVIDDGLQV KITDNALSRD LFPMDYHCLG DNENRPVRWM 180

ALESLVNNDF SSASDVWAFG VTLWELMTLG QTPYVDIDPF EMAAYLKDGY RIAQPINCPD 240

ELFAVMACCW ALDPEERPKF QQLVQCL 267

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005886	; C:plasma membrane
GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity
GO:0042813	; F:Wnt-activated receptor activity
GO:0050919	; P:negative chemotaxis
GO:0043410	; P:positive regulation of MAPK cascade
GO:0016055	; P:Wnt receptor signaling pathway

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.
IPR003306	; WIF.

Pfam

PF07714	; Pkinase_Tyr; 1.
PF02019	; WIF; 1.

SMARTs

SM00219

; TyrKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.
PS50814	; WIF; 1.

Prints

PR00109

; TYRKINASE.

Created Date

20-Feb-2013