EPS-TAG-00070

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-TAG-00070

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	236.3	2.5E-70	1	169	169

Status

Unreviewed

Ensembl Protein

ENSTGUP00000007338

UniProt Accession

H0Z9T5;

Protein Name

Protein Synonyms/Alias

Gene Name

TNS3

Gene Synonyms/Alias

TNS3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000007104	ENSTGUP00000007338	ENSTGUT00000007411

Organism

Taeniopygia guttata

Functional Description

Protein Length

1435

Protein Sequence
(FASTA)

MEEGSELDLT YITERIIAVS FPAGCSEETY LHNLQEVTQM LKSKHGDNYL VLNLSEKRYD 60

LAKLNPKIMD VGWPDLYAPL LDKVCTICKA MESWLDNDPQ HVVVIHCRGG KGRIGVVISS 120

YMHFINVSAS ADQALDRFAM KKFFDDKVSA LMQPSQRRYV QFLSGLLSGS VKMNTTPLFL 180

HYVILHGIPN LDAGGACWPF LKLYQAMQPV YTSGIYSIGS ENQSRICISI DPAQLLKGDI 240

MVKCMAQRMW LLKADQILIS ECSETALLGN ILLNSCPLFS DDRFPDYSKV ELVFSGTPEK 300

IQGCEHLQND HGVIVDYNTS DPLICWYSYK NMNPDGEVLH TQGPIDGSLY AKVRMKSSSD 360

NNICGVVQGI HVTGSPDHSD HTLSVSSDSG HSTASIRTDK TEELLVPEVK RGLSPQEKAE 420

LDQLLSGFGL EDSVSTTKDI TDAQSKYSVT HHIVPAHIHM NEVAEMKDRE TDILDNEMPN 480

HDLHSVDSIG TFSSSEGQHS THLGNFSCHK SSQNSLLSDS FGSNAGEEHH NAFAADMGIS 540

VDSLFERSFG STEPKSSEQL QQNPSVSPHL QAYGPSNYST QTWVRQQQMV TAHQYGFAPE 600

NEITVGIHYT VENLGSVQRQ SQVPDAPTRG SSSKDAVQRG LGSMLDAAQA EEHASADNFK 660

SSQKNTNGLD LGQNAGDVPA SPTLDIDQSI EQLNRLILEL DPTFEPIPTC INTLTSDRNQ 720

SLTNGSVGGG CQASSGLPPR PVAERVTSAA GSLGARAPPP LSGRLRKLSV GQYDSDIPGE 780

SSYNMCGWMK SPASHHAVIP GSPVAGGKTK EMIVVHYQDE IDGGVFSTIK NGNEAVTFTS 840

AFPLSPEVKY AKRSAAHLSC TEPFLVRTTP APHHSTKPPK STKYHHTQPL PSAQVPRLPR 900

PSAGRSLCAS AARSTAPAGS GALRGRGGES RAGKGRGGRE QVRPSGKPNL ITVGDLRPAA 960

AASSVEIKWK EEAMVVLSIF PSSSLAFSSP SCQSSLSLPP SLEHSLKVMA LLAFDIEPIL 1020

EGILPEPPLS ALKSQSYTEA INLSVVMSDS TVGTNSLLRA NMQTDPSFQS CFASSFLHHR 1080

GGNLHAQPPL PEKKRSSEGE RSFASESPSS SGFSSPHSGS TISIPFPNVL PDFSKMLSPS 1140

PAPENSADKH VTVKFVQDTS KFWYKPDISR EQAIAVLKER EPGSFIVRDS HSFRGAYGLA 1200

MKVATPPPSV LQLKKVGDLS NELVRHFLIE CTQKGVRLKG CPNEPYFGNL AALVYQHSIT 1260

PLALPCKLLI PDRDPLEEVA ETSPQTAINS AAELLKQGAA CNVWYLNSVE MESLTGYQAV 1320

QKAFSLTLMQ DPSPISTTVH FKVSAQGITL TDNQRKLFFR RHYSVNTVIF CALDPQDRKW 1380

LKDGLSAKVF GFIARKQGGA TDNVCHLFAE HDPEQPASAI VNFVSKVMIG SQKKI 1435

Nucleotide Sequence
(FASTA)

ATGGAGGAAG GCTCTGAACT TGACCTCACT TACATCACAG AGCGGATTAT TGCTGTGTCC 60

TTCCCTGCTG GCTGTTCTGA GGAAACTTAC CTCCACAATC TACAAGAAGT AACACAAATG 120

CTCAAATCCA AACATGGTGA TAATTACTTG GTATTAAACC TCTCTGAAAA GAGGTATGAC 180

CTTGCCAAGC TTAACCCAAA GATTATGGAT GTGGGGTGGC CTGATCTCTA TGCTCCACTT 240

CTTGATAAAG TGTGCACCAT CTGCAAGGCC ATGGAGTCCT GGCTGGACAA TGATCCTCAA 300

CATGTGGTGG TGATCCACTG CAGAGGAGGA AAAGGAAGGA TAGGTGTAGT CATATCATCA 360

TATATGCACT TTATCAATGT TTCTGCAAGT GCTGATCAGG CTCTAGACAG ATTTGCTATG 420

AAGAAATTCT TTGATGATAA AGTTTCAGCT TTAATGCAGC CATCCCAAAG AAGATATGTG 480

CAGTTCTTAA GTGGCCTTCT ATCTGGATCT GTGAAAATGA ACACAACCCC TCTTTTCCTG 540

CACTATGTTA TTCTTCATGG CATCCCCAAC TTAGATGCTG GGGGAGCTTG TTGGCCTTTT 600

CTGAAGTTAT ACCAGGCTAT GCAACCAGTT TATACATCTG GAATATATAG CATAGGGTCA 660

GAAAATCAAA GTCGAATCTG CATTTCTATA GACCCTGCCC AGCTTTTGAA AGGAGATATT 720

ATGGTGAAAT GTATGGCACA AAGAATGTGG CTTTTAAAAG CAGATCAAAT CCTGATTTCT 780

GAGTGCTCTG AAACTGCTCT CCTGGGAAAC ATCTTGCTGA ATTCCTGTCC TTTGTTCTCA 840

GATGACCGTT TTCCTGACTA CAGTAAGGTG GAATTAGTGT TTTCAGGAAC TCCAGAGAAA 900

ATTCAAGGGT GTGAACACCT TCAGAATGAT CATGGAGTAA TAGTTGATTA CAATACATCA 960

GACCCACTAA TATGCTGGTA TTCCTATAAA AATATGAACC CTGATGGGGA AGTATTGCAT 1020

ACCCAAGGTC CCATTGATGG CAGTCTGTAT GCAAAAGTGA GAATGAAGAG CTCTTCAGAC 1080

AACAATATCT GTGGTGTTGT TCAGGGTATT CATGTTACAG GCAGTCCTGA TCACAGTGAT 1140

CATACCCTGT CTGTCAGTAG TGATTCTGGA CACTCCACAG CTTCCATCAG AACAGACAAG 1200

ACTGAGGAAC TCCTTGTCCC AGAAGTTAAA CGGGGTCTGA GCCCACAAGA GAAGGCAGAA 1260

CTAGACCAGC TACTTAGTGG CTTTGGACTA GAGGATTCTG TCAGCACCAC CAAAGATATT 1320

ACTGATGCTC AAAGCAAGTA CAGTGTTACT CACCACATAG TGCCAGCTCA CATTCACATG 1380

AATGAAGTTG CCGAAATGAA GGACAGGGAG ACTGATATTC TGGATAATGA AATGCCTAAT 1440

CATGACCTTC ACAGTGTGGA CAGCATTGGG ACATTTTCTT CCTCAGAAGG GCAGCACTCC 1500

ACCCACCTAG GGAACTTCAG TTGCCACAAG AGCAGTCAAA ACTCACTTCT TTCAGACAGT 1560

TTTGGAAGTA ATGCTGGGGA AGAGCATCAC AATGCTTTTG CTGCAGACAT GGGAATTAGT 1620

GTGGATTCCC TCTTTGAAAG ATCATTTGGA AGCACTGAGC CAAAGTCATC TGAGCAATTG 1680

CAACAGAATC CTTCTGTCTC ACCCCATCTA CAAGCCTATG GCCCGAGTAA CTACTCTACT 1740

CAGACCTGGG TACGCCAGCA GCAGATGGTC ACTGCTCACC AATATGGTTT TGCCCCAGAG 1800

AATGAAATTA CTGTTGGCAT TCATTACACT GTGGAGAATT TGGGCAGTGT CCAGAGGCAG 1860

TCCCAAGTCC CAGATGCTCC AACACGTGGC TCTAGCAGCA AAGATGCTGT GCAGAGAGGG 1920

CTAGGAAGCA TGCTGGATGC TGCACAAGCT GAAGAACATG CAAGTGCTGA CAATTTTAAG 1980

TCAAGTCAGA AGAACACAAA TGGCCTGGAT CTAGGACAAA ATGCTGGAGA CGTACCAGCT 2040

TCTCCAACTT TGGATATTGA TCAGTCTATT GAACAATTGA ACAGGCTGAT CTTGGAGTTA 2100

GACCCTACAT TTGAACCTAT CCCAACCTGC ATTAACACTC TCACCAGTGA CAGAAATCAA 2160

AGCTTAACAA ATGGCAGTGT GGGTGGGGGG TGTCAAGCCA GCAGTGGACT CCCCCCACGC 2220

CCCGTGGCCG AGCGGGTGAC CAGCGCTGCC GGCTCCCTCG GCGCCCGCGC TCCCCCGCCG 2280

CTGTCGGGAA GGCTCAGAAA GTTAAGTGTT GGGCAGTATG ACAGTGATAT TCCTGGGGAG 2340

TCATCGTATA ACATGTGTGG ATGGATGAAG TCTCCTGCTA GTCACCACGC TGTAATTCCA 2400

GGATCACCGG TTGCTGGAGG GAAAACCAAG GAGATGATTG TTGTACATTA CCAAGATGAA 2460

ATAGATGGGG GAGTCTTCTC CACAATAAAA AATGGAAATG AAGCTGTCAC ATTCACATCA 2520

GCTTTTCCCC TGTCACCAGA GGTGAAATAT GCCAAAAGGT CAGCAGCCCA TCTGAGCTGT 2580

ACAGAACCAT TTCTGGTAAG AACAACACCC GCCCCCCACC ACTCAACAAA ACCCCCAAAA 2640

TCAACCAAAT ACCACCACAC ACAACCCCTG CCCTCAGCCC AAGTTCCCAG ACTACCTCGT 2700

CCGTCTGCCG GCCGCTCGCT CTGCGCCTCC GCAGCCCGGA GCACAGCACC CGCTGGGAGC 2760

GGCGCTCTAC GTGGAAGAGG CGGCGAGAGC CGGGCCGGGA AAGGTAGGGG GGGGAGGGAA 2820

CAAGTCAGAC CCAGCGGGAA GCCTAATCTA ATAACTGTCG GGGACCTGCG GCCTGCTGCT 2880

GCTGCGAGCT CTGTAGAAAT TAAGTGGAAG GAAGAGGCAA TGGTGGTGTT GTCAATCTTC 2940

CCAAGCTCTT CCCTAGCCTT CTCCTCCCCA AGTTGTCAAT CCTCCCTTTC TCTGCCCCCT 3000

TCCCTAGAAC ATTCCCTGAA AGTAATGGCT TTGCTAGCAT TTGATATTGA ACCTATTCTG 3060

GAAGGCATCT TGCCTGAGCC ACCACTGTCA GCATTGAAAT CTCAAAGTTA CACAGAAGCC 3120

ATTAACCTCT CTGTGGTGAT GTCTGACAGC ACCGTGGGCA CTAACTCTTT GCTGAGGGCC 3180

AACATGCAGA CTGATCCCTC CTTTCAGAGC TGTTTTGCAT CTTCATTTTT GCATCACCGT 3240

GGAGGGAACC TACATGCTCA GCCGCCTCTT CCAGAGAAGA AGAGGTCCTC TGAAGGAGAA 3300

CGTTCCTTTG CCTCTGAATC ACCTTCTTCA AGTGGCTTCT CTAGCCCTCA TAGTGGAAGC 3360

ACAATCAGCA TTCCCTTCCC AAATGTCCTC CCAGATTTCT CAAAAATGTT AAGCCCTTCC 3420

CCAGCGCCAG AAAACTCAGC TGATAAACAC GTGACTGTAA AATTTGTTCA GGACACATCC 3480

AAGTTCTGGT ATAAGCCAGA TATTTCAAGA GAACAAGCCA TTGCTGTTCT CAAGGAAAGG 3540

GAACCTGGGT CTTTCATTGT TCGAGACAGT CATTCTTTCC GGGGAGCCTA TGGGCTGGCA 3600

ATGAAAGTTG CCACACCACC TCCTTCTGTG CTACAGTTAA AGAAAGTTGG AGATTTGTCA 3660

AATGAACTTG TAAGGCATTT TCTGATTGAA TGTACTCAGA AGGGGGTACG TTTGAAAGGA 3720

TGCCCGAATG AGCCATATTT TGGTAATTTG GCAGCTCTGG TGTATCAGCA TTCCATCACT 3780

CCACTGGCAT TGCCCTGCAA GCTCCTCATC CCAGACAGAG ATCCCTTGGA GGAGGTAGCA 3840

GAAACTTCCC CACAAACTGC TATAAACTCA GCTGCGGAGC TTCTCAAACA GGGTGCAGCT 3900

TGTAACGTTT GGTACCTGAA TTCAGTAGAG ATGGAGTCCC TCACAGGATA CCAGGCAGTA 3960

CAGAAAGCCT TCAGCCTGAC GCTGATGCAA GATCCATCTC CTATCTCAAC CACAGTCCAT 4020

TTCAAGGTGT CTGCTCAAGG AATCACACTG ACAGATAATC AAAGAAAACT CTTTTTTCGG 4080

CGACATTATT CAGTCAACAC TGTTATTTTC TGTGCTTTGG ATCCACAGGA CAGAAAGTGG 4140

TTGAAAGATG GCCTTTCTGC AAAAGTGTTT GGGTTCATTG CCAGGAAGCA AGGCGGTGCC 4200

ACAGACAACG TATGCCACCT CTTTGCAGAG CATGATCCAG AACAACCTGC CAGTGCCATT 4260

GTAAACTTTG TATCAAAAGT CATGATTGGA TCCCAGAAGA AGATCTGA 4308

Domain Profile

S: 4     tedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcserry  63

         +e+g +ldlty+teriiavsfPa  +ee+y  nl+ev ++l+skh ++y++ nl se+ry

Q: 1     MEEGSELDLTYITERIIAVSFPAGCSEETYLHNLQEVTQMLKSKHGDNYLVLNL-SEKRY  59

         78999*************************************************.*****

S: 64    dltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGvivc  123

         dl+kln+k++++g++dl aP l+k+++ick+++ Wl +d+++vvv+hc+ggkgr+Gv+++

Q: 60    DLAKLNPKIMDVGWPDLYAPLLDKVCTICKAMESWLDNDPQHVVVIHCRGGKGRIGVVIS  119

         ************************************************************

S: 124   ayllaseisakadealdtfgerrtredkvagvkqPsqrryvsyfsqllkg  173

         +y+++ ++sa+ad+ald+f+++++ +dkv++  qPsqrryv++ s+ll+g

Q: 120   SYMHFINVSASADQALDRFAMKKFFDDKVSALMQPSQRRYVQFLSGLLSG  169

         ***********************************************987

Domain Sequence
(FASTA)

MEEGSELDLT YITERIIAVS FPAGCSEETY LHNLQEVTQM LKSKHGDNYL VLNLSEKRYD 60

LAKLNPKIMD VGWPDLYAPL LDKVCTICKA MESWLDNDPQ HVVVIHCRGG KGRIGVVISS 120

YMHFINVSAS ADQALDRFAM KKFFDDKVSA LMQPSQRRYV QFLSGLLSG 169

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016477	; P:cell migration
GO:0008284	; P:positive regulation of cell proliferation

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR011993	; PH_like_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR013625	; PTB.
IPR006020	; PTyr_interaction_dom.
IPR000980	; SH2.
IPR014020	; Tensin_phosphatase_C2-dom.

Pfam

PF08416	; PTB; 1.
PF10409	; PTEN_C2; 1.
PF00017	; SH2; 1.

SMARTs

SM00462	; PTB; 1.
SM00252	; SH2; 1.

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS50001	; SH2; 1.

Prints

Created Date

20-Feb-2013