EPS-TAG-00028

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-TAG-00028

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	189.4	8.6E-56	11	226	216

Status

Unreviewed

Ensembl Protein

ENSTGUP00000008127

UniProt Accession

H0ZC19;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1D

Gene Synonyms/Alias

PPM1D;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000007882	ENSTGUP00000008127	ENSTGUT00000008212

Organism

Taeniopygia guttata

Functional Description

Protein Length

451

Protein Sequence
(FASTA)

CLLFAWFLLA AEWPKTMTGL PSTSGTTASV VIIRGSKMYV AHVGDSGVVL GVQDDPKDDF 60

VRAVEVTQDH KPELPKERER IEGLGGSVIN KSGVNRVVWK RPRLTHNGPV RRSTVIDQIP 120

FLAVARALGD LWSYDFYSGE FVVSPEPDTS VHTIDPQKHK YIILGSDGLW NMIPPQDAIS 180

MCQDHEEKKY FMGEARQSCA RMLVGRALGR WRQRMLRADN TSAIVICIAP LRERGRWDGD 240

EELVLNLAEG PSYSSPDAGS LSPSRCCTPP LKLVEDDPWP RLNSAEPIPP LLHSNMLSEK 300

YLELPNEIAK SNLPSSGGTP KDSAPQEEKC SKALALRLQE SYSNGLSVSL SPSNSANSGT 360

DQKGFKVSPS GHSKAQDAER PPPASFKRTL EESNSGPALK KPRRGLARGP GEAAGAQRRS 420

PARMAMRRSL RGQKKLSSSL FHPPRKAVCV C 451

Nucleotide Sequence
(FASTA)

TGTCTGTTGT TTGCCTGGTT TCTCCTTGCA GCAGAGTGGC CCAAGACCAT GACAGGCCTG 60

CCCAGCACGT CGGGGACCAC GGCCAGCGTG GTGATCATCC GCGGCTCCAA GATGTACGTG 120

GCCCACGTGG GCGACTCAGG AGTGGTGCTG GGGGTCCAGG ATGACCCCAA GGATGACTTT 180

GTGAGAGCTG TGGAGGTGAC ACAGGACCAC AAGCCAGAAC TTCCCAAAGA AAGGGAGAGA 240

ATTGAAGGCC TTGGAGGCAG CGTGATCAAT AAGTCTGGTG TGAACCGTGT GGTGTGGAAG 300

AGGCCCCGGC TGACCCACAA CGGCCCCGTG CGCCGCAGCA CCGTCATCGA CCAGATCCCC 360

TTCCTGGCCG TGGCCAGGGC CCTGGGTGAT CTCTGGAGCT ACGACTTCTA CAGTGGGGAA 420

TTCGTGGTGT CCCCCGAGCC CGACACCAGC GTGCACACCA TTGACCCCCA GAAGCACAAG 480

TACATCATCC TTGGCAGTGA CGGGCTCTGG AACATGATCC CACCTCAGGA TGCCATCTCC 540

ATGTGCCAGG ATCACGAGGA GAAGAAGTAT TTCATGGGCG AGGCGCGGCA GTCCTGTGCC 600

CGGATGCTGG TGGGTCGGGC TCTGGGCCGC TGGCGGCAGC GGATGCTGCG GGCGGACAAC 660

ACGAGCGCCA TCGTCATCTG CATCGCGCCC CTGCGCGAGC GCGGCCGCTG GGACGGCGAC 720

GAGGAGCTGG TGCTGAACCT GGCCGAGGGG CCCAGCTACA GCAGCCCCGA TGCCGGCAGC 780

CTCTCCCCCT CCCGCTGCTG CACGCCCCCC CTCAAGCTTG TAGAAGATGA CCCCTGGCCA 840

CGACTGAACT CTGCTGAGCC CATTCCTCCC CTCCTGCACA GCAACATGCT CTCAGAAAAA 900

TACCTGGAGC TGCCAAACGA GATTGCCAAA AGCAATTTAC CTTCCTCGGG AGGAACCCCG 960

AAGGATTCAG CCCCCCAGGA GGAGAAGTGC AGCAAAGCCC TGGCTTTGAG GCTACAGGAA 1020

TCCTACAGCA ATGGTTTGTC GGTCAGCCTC TCCCCTTCCA ACTCGGCCAA CTCAGGCACG 1080

GACCAAAAAG GCTTCAAGGT GTCCCCTAGC GGGCACAGCA AGGCGCAGGA CGCGGAGAGG 1140

CCGCCCCCGG CCAGCTTTAA GCGGACACTG GAGGAGTCCA ACTCGGGCCC GGCGCTGAAG 1200

AAGCCGCGGC GGGGGCTGGC GCGGGGCCCG GGCGAGGCCG CGGGCGCGCA GCGCAGGAGC 1260

CCGGCCCGGA TGGCCATGCG CCGCAGCCTC CGCGGGCAGA AGAAGCTCAG CAGCTCCCTG 1320

TTCCACCCGC CCCGCAAAGC CGTGTGCGTC TGC 1353

Domain Profile

S: 90    lkvleeksldidksGstavvalikdsklyvanvGdSravLcrngk.......avelssdH  142

          +++++++  +++sG+ta+v++i++sk+yva+vGdS++vL+ +++       ave+++dH

Q: 11    AEWPKTMTGLPSTSGTTASVVIIRGSKMYVAHVGDSGVVLGVQDDpkddfvrAVEVTQDH  70

         4799**************************************77656999999*******

S: 143   kpsredEleRieeaggsvilkdga.Rv.....................lGvLavsRalGd  180

         kp+ ++E+eRie  ggsvi+k+g+ Rv                     +++Lav+RalGd

Q: 71    KPELPKERERIEGLGGSVINKSGVnRVvwkrprlthngpvrrstvidqIPFLAVARALGD  130

         ************************************************************

S: 181   lylk......pyvtpePevtshrltsede.fliLasDGlwdvvsneeavslvrdvle...  230

         l+++      ++v+peP++++h+++++++ ++iL+sDGlw+++++++a+s+++d++e

Q: 131   LWSYdfysgeFVVSPEPDTSVHTIDPQKHkYIILGSDGLWNMIPPQDAISMCQDHEEkky  190

         ************************************************************

S: 231   .kkeaeqeaakkLvklalargsk.....dnvsaivv  260

          ++ea q++a +Lv +al r+++     dn+saiv+

Q: 191   fMGEARQSCARMLVGRALGRWRQrmlraDNTSAIVI  226

         **********************************97

Domain Sequence
(FASTA)

AEWPKTMTGL PSTSGTTASV VIIRGSKMYV AHVGDSGVVL GVQDDPKDDF VRAVEVTQDH 60

KPELPKERER IEGLGGSVIN KSGVNRVVWK RPRLTHNGPV RRSTVIDQIP FLAVARALGD 120

LWSYDFYSGE FVVSPEPDTS VHTIDPQKHK YIILGSDGLW NMIPPQDAIS MCQDHEEKKY 180

FMGEARQSCA RMLVGRALGR WRQRMLRADN TSAIVI 216

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0000086	; P:G2/M transition of mitotic cell cycle
GO:0035970	; P:peptidyl-threonine dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00332

; PP2Cc; 1.

Prosites

Prints

Created Date

20-Feb-2013