EKS-TAG-00342

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00342

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	308.2	4.2E-92	27	293	267

Status

Unreviewed

Ensembl Protein

ENSTGUP00000008294

UniProt Accession

H0ZCI4;

Protein Name

Protein Synonyms/Alias

Gene Name

MYO3B

Gene Synonyms/Alias

MYO3B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000008038	ENSTGUP00000008294	ENSTGUT00000008381

Organism

Taeniopygia guttata

Functional Description

Protein Length

1104

Protein Sequence
(FASTA)

RKPLYGLFQY NSSMIGLESL ADPSDTWEII ETIGKGTYGK VYKVANKKDG SLAAVKILDP 60

VSDVDEEIEA EYNILQFLPN HPNVVRFYGM FYKADQYVGG QLWLVLELCN GGSVTELVKG 120

LLKCGRRLDE AIISYILYGA LLGLQHLHNN RIIHRDVKGN NILLTTEGGV KLVDFGVSAQ 180

LTSTRLRRNT SVGTPFWMAP EVIACEQQYD YSYDARCDVW SLGITAIELG DGDPPLFDMH 240

PVKTLFKIPR NPPPTLLHPE KWCRGFNHFI SQCLIKDFEK RPSVTHLLEH PFIKQVHGKD 300

MSLQKQLAEL IQEQQQLCSV AKTRHERIHT RRPYHVDRAD KYSLDDDLVN LEVLNEETII 360

HQLQKRYADL QIYTYVGDIL IALNPFQNLS IYSPQFSKLY HGVKRSSNPP HIFASADAAY 420

QSMVTFSKDQ CIIISGESGA GKTESAHLIV QHLTFLGKAN NRALREKILQ VNPLVEAFGN 480

ACTAINDNSS RFGKYLEMMF TPTGAVMGAK ISEYLLEKSR VIKQAVGEKN FHIFYYIYAG 540

LYHQKKLSEY RLPDKKPPRY IDNETGRVMH DIVTKDSYGR QFEAIQHCFR IIGFTDEEVY 600

SVYRILTGIL NTGNIEFAAI SSQHQTDKSE VPNPEALDNA AALLSIGSEE LQEALTSHCV 660

VTRGETIIRT NTVDKAADVR DAMSKALYGR LFSWIVNRIN TLLQPDKNIC SAESGMNVGI 720

LDIFGFENFA RNSFEQLCIN IANEQIQFYF NQHIFALEQM EYQSEGIDAT TVEYEDNRPL 780

LDMFLQKPMG LLSLLDEESR FPQATDLTLV DKFEDNLRCK YFWRPKGVEL SFGIQHYAGK 840

VLYDASAFLE KNRDTLPADI VVVLRTSENK LLQQLFSSPL TKTGNLAQAR ARVTAASRSL 900

PPQLSAGRIK VDTMEVMRHP EETTNMKRQT VASYFRYSLM DLLSKMVVGQ PHFIRCIKPN 960

DDREALMFSH ERVLLQLRYT GILETVKIRQ KGYSHRILFE EFVKKYYYLA FKAHETPLGS 1020

RENCLAILEK SKLDNWILGK TKVFLKYYHI EQLNLFLREV IGRVVVMQAY IKGWLGARRY 1080

KKVKDKRENS AITIQSAWRG YEAR 1104

Nucleotide Sequence
(FASTA)

AGGAAGCCAT TGTATGGATT GTTTCAATAT AATTCCAGTA TGATTGGACT AGAATCATTA 60

GCTGATCCCT CAGATACCTG GGAAATTATA GAAACTATTG GGAAAGGCAC TTATGGTAAA 120

GTCTACAAGG TTGCTAATAA GAAAGATGGA AGCTTGGCAG CAGTAAAGAT TCTGGATCCT 180

GTCAGTGATG TAGATGAAGA AATTGAAGCT GAATATAATA TTTTGCAGTT TCTTCCCAAT 240

CATCCTAATG TTGTTAGATT TTATGGGATG TTTTACAAAG CAGATCAATA TGTGGGAGGA 300

CAGCTCTGGC TAGTACTTGA GCTGTGCAAT GGAGGTTCTG TCACAGAGCT TGTCAAAGGC 360

CTGCTGAAGT GTGGCCGAAG ATTGGATGAA GCTATCATCT CATACATCTT GTATGGTGCT 420

CTCTTGGGCC TTCAGCATTT ACACAATAAC CGGATCATTC ATCGTGATGT GAAAGGGAAC 480

AACATTCTCC TGACAACAGA AGGTGGAGTC AAGCTCGTTG ATTTTGGTGT TTCAGCCCAG 540

CTCACCAGCA CACGGCTGCG TAGAAACACC TCAGTGGGAA CACCCTTTTG GATGGCACCT 600

GAGGTCATTG CTTGTGAACA ACAGTATGAC TACTCATATG ATGCTCGATG TGACGTATGG 660

TCCTTGGGAA TAACAGCTAT TGAACTGGGG GATGGAGACC CTCCTTTATT TGACATGCAT 720

CCGGTGAAAA CCCTTTTTAA AATTCCGAGA AACCCTCCAC CTACTTTGCT ACATCCTGAA 780

AAATGGTGCA GAGGATTCAA CCATTTCATT TCACAGTGTC TAATCAAAGA TTTTGAGAAG 840

CGTCCTTCAG TCACCCATCT TTTGGAACAT CCGTTTATTA AACAAGTACA CGGTAAAGAT 900

ATGTCTTTAC AAAAACAGCT GGCTGAGCTT ATCCAAGAAC AGCAGCAGCT GTGCTCCGTA 960

GCCAAAACAA GGCATGAACG AATACATACT AGAAGACCTT ACCATGTGGA CAGAGCTGAC 1020

AAGTACTCTC TAGATGATGA TCTGGTAAAT CTAGAAGTTC TCAATGAGGA AACAATTATC 1080

CATCAGCTGC AAAAACGTTA TGCTGACTTA CAGATTTATA CTTATGTTGG AGACATTTTA 1140

ATAGCCTTGA ACCCCTTCCA GAATCTCAGC ATTTATTCTC CCCAGTTCTC CAAGCTTTAC 1200

CATGGTGTGA AGCGTTCATC AAATCCCCCC CACATATTTG CCTCTGCAGA TGCTGCCTAC 1260

CAAAGCATGG TTACATTCAG CAAGGATCAG TGCATTATCA TCAGTGGAGA AAGTGGTGCT 1320

GGAAAAACAG AAAGTGCCCA TCTGATCGTC CAACATTTGA CCTTCTTGGG AAAGGCCAAT 1380

AACCGTGCTT TGCGTGAGAA AATTCTTCAG GTGAATCCTC TGGTTGAAGC ATTTGGAAAT 1440

GCCTGCACTG CCATCAATGA TAACTCAAGT CGCTTTGGAA AGTATCTGGA AATGATGTTT 1500

ACACCTACAG GAGCTGTAAT GGGGGCAAAG ATTTCTGAAT ATCTACTTGA AAAATCAAGG 1560

GTCATAAAAC AGGCTGTGGG AGAAAAAAAT TTCCATATAT TTTATTATAT TTATGCTGGT 1620

CTTTATCATC AGAAGAAACT TTCTGAATAT AGGCTTCCTG ATAAAAAGCC TCCTAGATAT 1680

ATTGATAATG AAACTGGAAG AGTAATGCAT GATATTGTTA CTAAAGATTC CTATGGAAGA 1740

CAATTTGAAG CAATTCAGCA TTGTTTTAGA ATTATAGGAT TTACTGATGA GGAAGTGTAT 1800

TCAGTGTACA GAATACTGAC TGGAATCTTA AATACTGGAA ATATTGAGTT TGCTGCTATT 1860

TCTTCACAAC ACCAAACAGA TAAAAGTGAG GTTCCTAACC CAGAAGCTTT AGATAATGCT 1920

GCTGCACTAC TAAGCATTGG GTCAGAAGAA CTTCAAGAAG CCCTAACCTC CCATTGTGTT 1980

GTAACACGGG GCGAGACAAT TATCCGGACG AACACTGTGG ACAAAGCAGC GGACGTGCGG 2040

GATGCCATGT CAAAAGCACT TTATGGCCGG CTCTTCAGCT GGATCGTGAA TCGTATTAAT 2100

ACACTGCTTC AGCCAGATAA AAATATATGC AGTGCTGAAA GTGGGATGAA TGTTGGAATA 2160

CTAGATATAT TTGGATTTGA GAACTTCGCA AGAAATTCTT TTGAACAACT GTGCATAAAT 2220

ATTGCTAATG AACAGATCCA GTTTTATTTC AATCAGCATA TCTTTGCACT GGAGCAGATG 2280

GAATACCAGA GTGAGGGAAT TGATGCCACT ACAGTGGAGT ATGAGGACAA CCGTCCACTT 2340

CTAGATATGT TCCTTCAGAA ACCCATGGGT CTCCTGTCTC TGCTAGATGA AGAAAGTCGA 2400

TTTCCTCAGG CAACAGACCT AACTTTAGTT GATAAGTTTG AAGATAACTT ACGATGCAAA 2460

TACTTTTGGA GACCAAAAGG AGTGGAGCTG TCATTTGGAA TTCAGCACTA TGCTGGAAAG 2520

GTATTATATG ATGCCTCTGC ATTCCTTGAG AAGAACAGAG ACACTCTTCC TGCTGACATA 2580

GTGGTGGTGT TACGAACTTC AGAGAACAAG CTTCTTCAGC AGCTGTTCTC TAGCCCATTA 2640

ACAAAAACAG GTAATTTGGC ACAAGCAAGA GCCAGAGTGA CAGCAGCATC TCGGTCTCTG 2700

CCTCCACAGC TCAGTGCTGG GCGTATCAAG GTTGACACAA TGGAGGTTAT GCGGCATCCT 2760

GAGGAAACAA CTAACATGAA GCGGCAAACT GTGGCTTCCT ATTTTAGGTA TTCCCTCATG 2820

GATCTTTTAT CCAAAATGGT TGTTGGACAG CCTCACTTCA TCCGCTGCAT TAAACCTAAC 2880

GATGATCGAG AAGCACTGAT GTTTTCTCAT GAGAGAGTTC TGCTGCAGCT ACGATACACT 2940

GGAATTCTGG AAACTGTCAA AATACGTCAA AAAGGATATT CTCATCGCAT CCTCTTTGAG 3000

GAGTTTGTAA AAAAGTATTA CTACCTTGCG TTCAAGGCAC ATGAGACTCC CCTTGGTAGC 3060

AGAGAAAACT GTCTTGCCAT TTTGGAGAAG TCTAAACTTG ACAACTGGAT TCTTGGGAAA 3120

ACCAAGGTAT TCCTTAAGTA TTACCATATA GAGCAGTTAA ATTTGTTCCT GCGAGAAGTT 3180

ATAGGGAGGG TGGTGGTCAT GCAAGCCTAT ATCAAGGGAT GGCTCGGAGC AAGGAGGTAC 3240

AAGAAAGTAA AAGATAAAAG AGAAAATAGT GCTATTACAA TACAGTCAGC CTGGAGAGGA 3300

TATGAAGCTC GC 3312

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkkl.khpniv  59

         +e++e+igkG++gkvy+  +kk g+l+a+k+++  + +  ee++ e+++l+ l +hpn+v

Q: 27    WEIIETIGKGTYGKVYKVANKKDGSLAAVKILDPVS-DVDEEIEAEYNILQFLpNHPNVV  85

         799******************************998.9999**********98356****

S: 60    eylesflk.....eeelwlvmeylagGslsdlvk..eelkselkEeqiayilrevlkaLe  112

         +++++f+k       +lwlv+e+++gGs+++lvk   ++ ++l+E  i+yil ++l +L+

Q: 86    RFYGMFYKadqyvGGQLWLVLELCNGGSVTELVKglLKCGRRLDEAIISYILYGALLGLQ  145

         *******988888889******************7778899*******************

S: 113   ylHskkviHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaq  172

         +lH++++iHrd+k++niLlt+eg VkL+dfgv+aql++tr +r+t vgtp+wmAPEvia+

Q: 146   HLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIAC  205

         ************************************************************

S: 173   e...ekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfske  229

         e   + +Yd+++D+wslGItaiel +g+pP++d++p+k l+ki++n+pp+l +++k+++

Q: 206   EqqyDYSYDARCDVWSLGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCRG  265

         9777779*****************************************************

S: 230   fkefvekclqknpekRpsasellkhkFl  257

         f++f+++cl k++ekRps+++ll+h+F+

Q: 266   FNHFISQCLIKDFEKRPSVTHLLEHPFI  293

         ***************************7

Domain Sequence
(FASTA)

WEIIETIGKG TYGKVYKVAN KKDGSLAAVK ILDPVSDVDE EIEAEYNILQ FLPNHPNVVR 60

FYGMFYKADQ YVGGQLWLVL ELCNGGSVTE LVKGLLKCGR RLDEAIISYI LYGALLGLQH 120

LHNNRIIHRD VKGNNILLTT EGGVKLVDFG VSAQLTSTRL RRNTSVGTPF WMAPEVIACE 180

QQYDYSYDAR CDVWSLGITA IELGDGDPPL FDMHPVKTLF KIPRNPPPTL LHPEKWCRGF 240

NHFISQCLIK DFEKRPSVTH LLEHPFI 267

Keyword

ATP-binding; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0016459	; C:myosin complex
GO:0005524	; F:ATP binding
GO:0003774	; F:motor activity
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000048	; IQ_motif_EF-hand-BS.
IPR011009	; Kinase-like_dom.
IPR001609	; Myosin_head_motor_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00612	; IQ; 1.
PF00063	; Myosin_head; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00015	; IQ; 2.
SM00242	; MYSc; 1.
SM00220	; S_TKc; 1.

Prosites

PS50096	; IQ; 2.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00193

; MYOSINHEAVY.

Created Date

20-Feb-2013