EPS-TAG-00031

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-TAG-00031

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	179.1	1.2E-52	691	935	245

Status

Unreviewed

Ensembl Protein

ENSTGUP00000008615

UniProt Accession

H0ZDF3;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000008329	ENSTGUP00000008615	ENSTGUT00000008706

Organism

Taeniopygia guttata

Functional Description

Protein Length

1222

Protein Sequence
(FASTA)

RRLEPTEKPL QIVYDYLAGL GFDDPLRVQE EAANSDLSCM IRFYSEKPCQ VEQLDHILLS 60

GVYNVRKGKT QLHKWAERSV ILCGTCLIVS SVKDSHAGKM HILPLIGGKV EEMKRRQYTL 120

AFTSAGAQAQ TYHISFETLA ECQRWHRQAS KIVSMRFSMV DLSCYSLEEV PEHLFYSRDI 180

TYLNLRHNFM RTSGAGSLDS LCRFSQLKSL NLCHNRLGEF PVSLCEISTL TELNISCNGL 240

HCVPSQIGKL LNLQTFWLDG NFLTSLPEEM GNLQQLSCLG LSFNNFCELP AICEKLVTLD 300

KLALAGNLLE TLDLTVLNRM GHIKSVDLRL NNLKRTVADT LEGNKSVAYM DLRDNQMTNL 360

DLSSLVSLEQ LHCERNQLRE LTLSGFSLRA LYANSNCLTA VNIYPVPGLL TCLELSHNQL 420

QCVPDWACEA KKLEVLDVSY NLLLELPSRI LRSLSLRKLM VGHNHLQSLP LLLEHIPLEV 480

LDLQHNLLTT LPETLFVKAL NLRYLNASAN SLESLPSACL GEESLSMLQL LYLTNNNLTD 540

QCIPVLVGHP NLRILHLANN NLQTFPASKL SKLEHLEELN LSGNKLKTIP TTIANCKLLR 600

TLIAHSNEIS IFPEIMHLPH IQFVDLSCNE LTEILIPEAL PGALQELDLS GNTNLVLEHK 660

TLDIFSHITT LKIDAKPSLT ADSALSSAFW SHGVAEMAGQ RNKLCVSSLA LGSFAEGTEA 720

VYGMFDGDKN EELPRLLQCT MADVLLEEVQ QSDTMFMSNT FLVSHRKLGM AGQKLGSSAV 780

LCYIRNEVAD PASNFSLTVA NVGTCQAVLC RSGKALPLSK VFSLEQCSEE ARRVKEQKAI 840

ITEDNKVNGV TCCTRMLGCT YLHPWILPKP QVNSIPLTVQ DELLLLGNKA LWEHLSYAEA 900

VSAVRHLHDP LAAAKKLCTL AQSYGCQDNI GAMVVCLNIS EDNCTCEMHG LTLTGPGGFS 960

STTNKPATPS CSSGIASEFS SELSASEVSS EVGSTASDEH GAVGLDGSLL PRQERRCSLH 1020

PVPPSSIFQR QPSSATFSSN QSDNGLDSDD EQPVEGVITN GSKVEVEVDI HCCKGKGLEL 1080

EHPAADYSSS APGPEDDSGL VLIIRRQNSV NSNTVQRGLK EKCELQKSLS TCCLYGKKLS 1140

NGSIVPLEES LNLIEVATEA PKKKTGYFAA PSQMEPEDQF VVPPDLEEEV KEQMKQHHKD 1200

RADQELKEEL AASLPDEFDT AL 1222

Nucleotide Sequence
(FASTA)

AGGAGGCTGG AGCCCACAGA AAAACCCCTT CAGATTGTGT ATGACTACTT GGCTGGGTTG 60

GGTTTTGATG ATCCTCTCAG AGTGCAGGAA GAGGCAGCAA ACTCTGATCT CAGCTGCATG 120

ATTCGCTTTT ACAGTGAAAA GCCATGCCAA GTGGAACAGT TGGATCACAT CCTGCTCTCT 180

GGAGTCTATA ACGTACGCAA AGGAAAGACC CAGCTGCACA AGTGGGCAGA ACGCTCAGTC 240

ATTCTCTGTG GTACGTGCCT CATTGTGTCC TCAGTGAAGG ACAGCCATGC AGGGAAGATG 300

CACATCTTGC CACTCATTGG AGGGAAGGTG GAAGAGATGA AACGTCGGCA GTACACCCTT 360

GCTTTCACAT CTGCTGGAGC ACAAGCTCAG ACATACCACA TTTCCTTTGA AACCCTGGCA 420

GAGTGCCAGC GGTGGCACCG GCAAGCATCC AAGATTGTGT CTATGCGATT TAGTATGGTT 480

GATCTTTCAT GCTACAGCCT TGAGGAAGTA CCAGAGCACC TCTTCTACAG TCGAGACATC 540

ACCTACCTCA ACTTACGCCA CAATTTTATG AGAACAAGTG GAGCAGGGAG TCTTGACTCT 600

CTTTGCAGGT TTTCTCAATT GAAGAGTCTG AACTTGTGTC ATAATAGACT GGGAGAGTTT 660

CCTGTATCAC TGTGTGAGAT CTCTACTCTG ACAGAGCTTA ATATTTCCTG TAATGGACTT 720

CATTGCGTGC CAAGTCAGAT TGGCAAACTG TTGAATCTCC AGACTTTCTG GCTTGATGGC 780

AATTTCCTTA CATCCTTACC AGAAGAGATG GGAAACCTGC AGCAGCTTAG CTGTCTTGGA 840

CTTTCCTTCA ATAACTTCTG TGAACTGCCA GCAATTTGTG AGAAACTTGT CACCTTAGAC 900

AAACTAGCTC TGGCAGGGAA CTTGCTAGAG ACCTTGGACC TGACAGTACT GAACCGTATG 960

GGTCACATCA AAAGTGTGGA CCTGAGGCTC AACAACCTGA AGAGAACAGT GGCTGACACT 1020

CTGGAGGGGA ACAAATCTGT GGCTTACATG GATTTACGAG ACAATCAGAT GACAAATCTG 1080

GATCTGAGTT CCTTGGTCAG CCTGGAGCAG CTACACTGCG AGCGAAATCA GCTGAGAGAG 1140

CTGACCCTGA GCGGCTTCTC CCTTCGGGCC CTGTATGCCA ACAGCAACTG TCTGACAGCT 1200

GTCAATATTT ATCCAGTTCC TGGTCTACTG ACATGTCTAG AACTCTCTCA CAATCAACTA 1260

CAGTGTGTCC CAGACTGGGC CTGTGAAGCA AAGAAACTGG AAGTTTTGGA TGTGAGCTAC 1320

AACCTACTCT TGGAGCTTCC GTCGAGGATC CTCAGAAGCT TGAGTCTTCG GAAGTTGATG 1380

GTGGGGCACA ATCATCTGCA GAGCCTTCCA CTTCTTCTAG AACACATTCC ACTGGAGGTG 1440

CTGGACCTTC AGCACAATCT GTTGACTACA CTCCCAGAGA CACTCTTTGT CAAAGCTCTG 1500

AACCTCAGGT ACCTGAATGC ATCTGCAAAC AGCCTGGAGT CCTTGCCCTC CGCATGTCTG 1560

GGGGAGGAGA GTTTGAGCAT GCTGCAGCTG CTATACTTGA CTAATAACAA CCTCACAGAC 1620

CAATGCATCC CTGTCTTGGT GGGACACCCA AACCTACGGA TTTTGCATCT GGCAAACAAC 1680

AACCTGCAGA CTTTCCCTGC AAGCAAACTT AGTAAGCTGG AGCACTTGGA AGAGCTGAAT 1740

CTCAGTGGAA ACAAACTGAA AACAATTCCT ACAACGATTG CAAACTGCAA GCTCCTTCGT 1800

ACGCTTATTG CACACTCTAA TGAAATCAGC ATTTTTCCAG AAATCATGCA TTTGCCCCAT 1860

ATTCAGTTTG TGGATTTGAG CTGCAATGAG TTAACTGAAA TCCTAATCCC TGAAGCACTG 1920

CCAGGTGCCT TGCAAGAGCT GGATCTGAGT GGAAACACAA ACCTGGTCTT AGAACACAAG 1980

ACACTGGATA TCTTCAGTCA CATTACCACA CTGAAGATTG ATGCTAAGCC CTCCCTCACG 2040

GCAGACTCAG CACTCAGTTC TGCCTTCTGG AGTCACGGAG TAGCTGAGAT GGCAGGCCAA 2100

AGAAATAAGC TGTGTGTGTC ATCCTTGGCA CTGGGGAGCT TTGCAGAGGG GACGGAGGCT 2160

GTGTATGGCA TGTTTGATGG TGACAAGAAT GAAGAACTGC CACGTTTGCT GCAGTGCACC 2220

ATGGCCGATG TGCTCCTGGA GGAGGTACAG CAGTCTGACA CCATGTTCAT GTCCAACACC 2280

TTCTTGGTCT CCCACAGGAA GCTGGGCATG GCTGGGCAGA AGCTGGGCTC CTCTGCTGTC 2340

CTTTGCTACA TTCGTAACGA GGTGGCTGAT CCAGCCAGCA ACTTTTCTCT GACGGTGGCC 2400

AATGTGGGGA CGTGCCAAGC CGTTCTGTGC CGAAGTGGAA AAGCACTGCC TCTCTCCAAA 2460

GTCTTCAGCC TTGAACAATG TTCAGAAGAA GCCAGGAGAG TCAAGGAACA AAAAGCCATT 2520

ATAACAGAGG ACAATAAAGT CAATGGTGTG ACTTGCTGTA CTCGGATGCT GGGCTGCACG 2580

TACTTGCATC CTTGGATCCT GCCCAAACCA CAGGTCAATT CCATTCCATT GACTGTACAA 2640

GATGAGTTGC TACTTCTAGG GAACAAAGCT CTCTGGGAAC ACCTTTCTTA TGCAGAGGCT 2700

GTCTCAGCTG TGCGGCACCT ACACGACCCA CTAGCTGCTG CAAAAAAACT CTGCACTTTA 2760

GCCCAAAGCT ACGGTTGCCA AGACAATATT GGTGCAATGG TGGTATGTCT GAACATCAGT 2820

GAGGACAACT GCACGTGTGA GATGCACGGC CTCACTCTGA CAGGCCCTGG GGGATTTAGT 2880

TCTACCACCA ACAAACCAGC AACACCTTCA TGTAGCAGTG GAATTGCTTC AGAGTTCAGC 2940

AGTGAACTAT CTGCTTCTGA GGTTAGCAGT GAGGTGGGCT CTACTGCATC AGATGAACAT 3000

GGTGCTGTTG GTCTCGATGG CAGCTTGCTA CCACGACAAG AACGACGTTG CAGCCTACAT 3060

CCTGTGCCCC CCTCAAGCAT CTTTCAGCGC CAACCTTCCA GTGCCACCTT TTCTAGCAAC 3120

CAGTCTGACA ATGGTCTAGA TAGTGATGAT GAGCAGCCTG TGGAAGGTGT GATAACAAAC 3180

GGCAGTAAAG TGGAGGTAGA GGTGGACATC CATTGCTGTA AAGGAAAGGG TCTGGAATTG 3240

GAACATCCTG CTGCAGATTA CAGCTCTTCT GCTCCAGGGC CAGAGGATGA CTCTGGGCTT 3300

GTACTCATCA TTCGGAGGCA GAATAGTGTA AACAGCAACA CTGTGCAGAG AGGGCTCAAG 3360

GAGAAGTGTG AACTCCAAAA ATCTCTTTCC ACATGTTGTC TTTATGGAAA GAAGCTTTCC 3420

AATGGCTCCA TAGTGCCCTT GGAGGAGAGC CTCAACCTCA TCGAAGTAGC GACAGAGGCA 3480

CCTAAGAAGA AGACAGGCTA TTTTGCTGCT CCATCCCAGA TGGAGCCAGA AGATCAATTT 3540

GTGGTGCCAC CTGATCTGGA AGAGGAAGTG AAGGAACAAA TGAAGCAGCA CCACAAGGAC 3600

AGAGCAGATC AGGAGCTGAA AGAAGAACTT GCAGCATCGC TGCCAGATGA GTTTGACACA 3660

GCTTTGTAA 3669

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++gv+++ g+rn+++ ++ + ++f++ +e+     ++g++DG++++e  + +++++ ++l

Q: 691   SHGVAEMAGQRNKLCVSSLALGSFAEGTEA-----VYGMFDGDKNEELPRLLQCTMADVL  745

         789**********************98764.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++      +  + ++ ++Fl  +++l       ++ +k Gs+av+++i+++

Q: 746   LEEVQ------QSDTMFMSNTFLVSHRKL------GMAGQKLGSSAVLCYIRNEvadpas  793

         ***88......556678************......89***************9999999*

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcr+gka++ls+ ++ ++  +E +R++e+++ +++++  +v+Gv+

Q: 794   nfSLTVANVGTCQAVLCRSGKALPLSKVFSLEQCsEEARRVKEQKAIITEDN--KVNGVT  851

         ******************************9864399********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         +++R+lG++yl+p++ p+P+v s++lt +de l L+ + lw+++s  eavs+vr+ ++

Q: 852   CCTRMLGCTYLHPWILPKPQVNSIPLTVQDELLLLGNKALWEHLSYAEAVSAVRHLHD--  909

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + +aakkL++la+++g++dn+ a+vv

Q: 910   --PLAAAKKLCTLAQSYGCQDNIGAMVV  935

         ..************************97

Domain Sequence
(FASTA)

SHGVAEMAGQ RNKLCVSSLA LGSFAEGTEA VYGMFDGDKN EELPRLLQCT MADVLLEEVQ 60

QSDTMFMSNT FLVSHRKLGM AGQKLGSSAV LCYIRNEVAD PASNFSLTVA NVGTCQAVLC 120

RSGKALPLSK VFSLEQCSEE ARRVKEQKAI ITEDNKVNGV TCCTRMLGCT YLHPWILPKP 180

QVNSIPLTVQ DELLLLGNKA LWEHLSYAEA VSAVRHLHDP LAAAKKLCTL AQSYGCQDNI 240

GAMVV 245

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Schizosaccharomyces pombe"; ?>