EKS-TAG-00546

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00546

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK1	442.1	5.8E-133	21	277	257

Status

Unreviewed

Ensembl Protein

ENSTGUP00000008943

UniProt Accession

H0ZED1;

Protein Name

Protein Synonyms/Alias

Gene Name

CAMK1

Gene Synonyms/Alias

CAMK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000008649	ENSTGUP00000008943	ENSTGUT00000009040

Organism

Taeniopygia guttata

Functional Description

Protein Length

332

Protein Sequence
(FASTA)

MPLGQDGPSW KKRIEDIQRI YDFRDVLGTG AFSEVVLAEE KATRKLVAIK CIAKKALEGK 60

ETSIENEIAV LHKIKHPNIV ALDDIYESGT HLYLIMQLVS GGELFDRIVE KGFYTERDAS 120

ALIRQILDAV KYLHDMGIVH RDLKPENLLY YSMDEDSKIM ISDFGLSKIE GCGSVMSTAC 180

GTPGYVAPEV LAQKPYSKAV DCWSIGVIAY ILLCGYPPFY DENDAKLFEQ ILQAEYEFDS 240

PYWDDISDSA KDFIQHLMEK DPGKRFTCEQ ALQHPWIAGD TALDKNIHQS VSEQIKKNFA 300

KSKWKQAFNA TAVVRHMRKL QLGTSQDVPG QT 332

Nucleotide Sequence
(FASTA)

ATGCCGCTGG GGCAGGATGG GCCCAGCTGG AAGAAGAGGA TCGAGGATAT TCAGCGGATC 60

TATGATTTCC GAGATGTCCT GGGCACGGGG GCCTTCTCCG AGGTGGTCCT GGCGGAGGAG 120

AAGGCGACAC GGAAGCTCGT GGCCATCAAG TGCATTGCCA AGAAGGCTCT GGAGGGAAAG 180

GAGACCAGCA TTGAGAACGA GATTGCCGTC CTCCACAAAA TCAAGCACCC CAATATCGTG 240

GCCTTGGATG ACATCTACGA GAGTGGCACC CACCTCTACC TCATCATGCA GCTGGTCTCG 300

GGGGGGGAAC TCTTTGACCG CATCGTGGAG AAGGGCTTCT ACACTGAGCG GGACGCCAGC 360

GCCCTGATCC GGCAGATCCT CGATGCCGTC AAATACCTGC ATGACATGGG TATCGTCCAC 420

CGTGACCTGA AGCCCGAGAA CCTGCTCTAC TACAGCATGG ATGAGGACTC CAAGATCATG 480

ATCAGTGACT TCGGGCTGTC AAAGATCGAG GGCTGTGGCA GTGTCATGTC CACAGCCTGC 540

GGCACCCCTG GCTATGTGGC CCCTGAGGTG CTAGCACAGA AGCCCTACAG CAAAGCAGTG 600

GATTGCTGGT CCATCGGAGT CATCGCCTAC ATCCTGCTCT GTGGTTACCC TCCTTTCTAT 660

GATGAGAATG ATGCCAAGCT CTTCGAGCAG ATCCTGCAGG CTGAGTACGA GTTTGACTCA 720

CCATACTGGG ATGATATCTC GGACTCAGCC AAGGACTTTA TCCAGCACCT GATGGAGAAG 780

GACCCTGGCA AGCGATTCAC CTGTGAGCAA GCCCTGCAGC ATCCCTGGAT TGCCGGGGAC 840

ACAGCCCTGG ACAAGAACAT CCACCAGTCA GTGAGTGAGC AGATCAAGAA GAATTTTGCA 900

AAGAGCAAGT GGAAGCAAGC TTTCAACGCC ACGGCGGTGG TGAGACACAT GAGAAAGCTG 960

CAGCTGGGAA CCAGCCAGGA CGTCCCTGGG CAGACA 996

Domain Profile

S: 1     yklkeklGeGafsevlkakekktqkavaikvikkkalkgkeesveneiavlkklkhpniv  60

         y++++ lG+Gafsev++a+ek+t+k vaik+i+kkal+gke+s+eneiavl+k+khpniv

Q: 21    YDFRDVLGTGAFSEVVLAEEKATRKLVAIKCIAKKALEGKETSIENEIAVLHKIKHPNIV  80

         899*********************************************************

S: 61    alkdiyesksklylvlelvtGGelfdrivekgvytekdasevikqvleavkylhelgivh  120

         al+diyes ++lyl+++lv+GGelfdrivekg+yte+das +i+q+l+avkylh++givh

Q: 81    ALDDIYESGTHLYLIMQLVSGGELFDRIVEKGFYTERDASALIRQILDAVKYLHDMGIVH  140

         ************************************************************

S: 121   rdlkPenllylskeedskikiadfGlskleeke.llktacGtvgyvapevlkqkkyskkv  179

         rdlkPenlly+s +edski+i+dfGlsk+e  + +++tacGt+gyvapevl+qk+ysk+v

Q: 141   RDLKPENLLYYSMDEDSKIMISDFGLSKIEGCGsVMSTACGTPGYVAPEVLAQKPYSKAV  200

         *******************************999**************************

S: 180   dvWsiGvityillcGyppfydekeekllekilkgeyefesPyWdeisesakdfikkllel  239

         d+WsiGvi+yillcGyppfyde+++kl+e+il++eyef+sPyWd+is+sakdfi++l+e+

Q: 201   DCWSIGVIAYILLCGYPPFYDENDAKLFEQILQAEYEFDSPYWDDISDSAKDFIQHLMEK  260

         ************************************************************

S: 240   dpekrytieqaledpWi  256

         dp kr+t+eqal++pWi

Q: 261   DPGKRFTCEQALQHPWI  277

         ****************8

Domain Sequence
(FASTA)

YDFRDVLGTG AFSEVVLAEE KATRKLVAIK CIAKKALEGK ETSIENEIAV LHKIKHPNIV 60

ALDDIYESGT HLYLIMQLVS GGELFDRIVE KGFYTERDAS ALIRQILDAV KYLHDMGIVH 120

RDLKPENLLY YSMDEDSKIM ISDFGLSKIE GCGSVMSTAC GTPGYVAPEV LAQKPYSKAV 180

DCWSIGVIAY ILLCGYPPFY DENDAKLFEQ ILQAEYEFDS PYWDDISDSA KDFIQHLMEK 240

DPGKRFTCEQ ALQHPWI 257

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006913	; P:nucleocytoplasmic transport
GO:0051149	; P:positive regulation of muscle cell differentiation
GO:0046827	; P:positive regulation of protein export from nucleus
GO:0071902	; P:positive regulation of protein serine/threonine kinase activity
GO:0043393	; P:regulation of protein binding
GO:0007165	; P:signal transduction

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013