EKS-TAG-00378

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00378

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	240.0	2.6E-71	27	275	249

Status

Unreviewed

Ensembl Protein

ENSTGUP00000009474

UniProt Accession

H0ZFW2;

Protein Name

Protein Synonyms/Alias

Gene Name

TAOK3

Gene Synonyms/Alias

TAOK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000009171	ENSTGUP00000009474	ENSTGUT00000009575

Organism

Taeniopygia guttata

Functional Description

Protein Length

892

Protein Sequence
(FASTA)

MRKGVPKDPE IADLFYKDDP EEIFVGLHEI GHGSFGAVYF ATNSHTNEVV AVKKMSYSGK 60

QTNEKWQDII KEVKFLQQLK HPNTIEYKGC YLKEHTAWLV MEYCLGSASD LLEVHKKPLQ 120

EVEIAAITHG ALQGLAYLHS HCRIHRDIKA GNILLTEPGQ VKLADFGSAS IVSPANSFVG 180

TPYCEQQFSL NGCPGLTWNI KIIGLSVMTT ALTERKPPLF NMNAMSALYH IAQNDSPRLQ 240

SNEWSDSFRG FVDYCLQKIP QERPSSTDLL RHDFVRRERP PRVLLDLIQR TKDAVRELDN 300

LQYRKMKKIL FQETRNGPLN ESQEEEEDSE HGSNLSRKMD SLGSNHSIPS MSVSTGSQSS 360

SVSSMQEVLD ESSPELVMMH SDESTINSTS SVVHKKDHVF IRDEVGHRDR RPEVRPTQSV 420

QNQALHYRNR ERFATIKSAS LVTRQIHEHE QENELREQMS GYKRMRRQHQ KQLIALENKL 480

KAEMDEHRLK LQKEVETHAN NSSIELEKLA KKQVAVMEKE AKAAAADEKK FQQQILAQQK 540

KDLATFLESQ KKQYKLCKEK IKEARNIFGA KGDHSTPKKE KQERISKHKE NLQHTQAEEE 600

AQLLSQQRLY YDKNCRFFKR KTMIKRHEME QQNIREVWHS SLPLPAFFNC LSFNCEKCKK 660

IGFGKWFFLQ LTRPEPENQL EYNKRREREL HRKHFMELRQ QPKNLKAMEM QIKKQFQDTC 720

KVQTKQYKAL KNHQLEVTPK SEHKTILKSL KDEQTRKLAI LAEQYEQSIN EMMASQALRL 780

DEAQEAECQA LRLQLQQEME LLNAYQSKIK MQTEAQHERE LQKLEQRVSL RRAHLEQKIR 840

RRSSSALQKE RKREDLVFCL ERQEREIETF DMESRMGFGN LVSFEFLKED YR 892

Nucleotide Sequence
(FASTA)

ATGCGCAAAG GGGTGCCAAA GGACCCAGAA ATAGCTGACC TCTTCTACAA AGATGATCCT 60

GAGGAAATAT TCGTGGGTTT ACATGAAATT GGACATGGAA GCTTTGGAGC AGTTTACTTT 120

GCTACGAATT CCCACACTAA TGAGGTGGTG GCAGTCAAGA AGATGTCGTA CAGTGGAAAG 180

CAAACAAATG AGAAATGGCA GGATATCATC AAAGAAGTCA AGTTTCTCCA ACAGCTGAAG 240

CACCCCAACA CCATAGAGTA CAAGGGCTGT TACCTGAAGG AGCACACGGC GTGGTTGGTT 300

ATGGAGTACT GTTTAGGATC AGCTTCTGAT TTGCTAGAAG TTCACAAGAA ACCACTCCAG 360

GAAGTGGAGA TTGCTGCCAT CACCCACGGT GCCTTGCAGG GGCTGGCCTA CCTGCACTCC 420

CACTGTAGGA TCCACAGGGA TATTAAAGCT GGAAATATTC TTCTAACAGA ACCAGGTCAG 480

GTGAAACTCG CTGATTTTGG GTCTGCATCT ATAGTTTCCC CTGCCAACTC TTTTGTGGGA 540

ACGCCTTACT GTGAACAGCA GTTTTCCTTG AATGGGTGTC CTGGTCTAAC TTGGAATATT 600

AAAATAATTG GCTTAAGTGT GATGACAACA GCACTGACTG AAAGGAAGCC TCCACTTTTC 660

AACATGAATG CAATGAGTGC CTTATATCAC ATAGCCCAGA ACGATTCCCC TAGGTTACAA 720

TCAAATGAAT GGTCAGACTC CTTTAGGGGA TTTGTTGATT ACTGCTTACA GAAAATACCT 780

CAGGAAAGGC CATCATCAAC AGATTTGTTA CGGCACGATT TTGTCCGCCG GGAGCGACCA 840

CCCAGGGTGC TGCTAGACCT GATCCAGAGG ACCAAGGACG CAGTGAGGGA GCTGGACAAC 900

CTGCAGTACC GCAAAATGAA GAAAATCCTC TTCCAGGAGA CACGCAACGG CCCCCTCAAC 960

GAGTCCCAGG AGGAGGAGGA GGACAGTGAG CATGGATCAA ACCTGAGTAG GAAGATGGAC 1020

AGTCTGGGCA GCAACCATTC CATCCCCAGC ATGTCTGTGA GCACAGGCAG CCAGAGCAGC 1080

AGTGTGAGCA GCATGCAGGA GGTCCTGGAT GAGAGCAGCC CTGAGCTGGT CATGATGCAT 1140

AGTGACGAGA GCACCATTAA TTCCACCTCC TCCGTTGTTC ACAAGAAGGA TCATGTATTT 1200

ATAAGGGATG AGGTGGGCCA CAGGGATCGC AGGCCTGAGG TGCGGCCTAC CCAGTCAGTG 1260

CAGAATCAGG CCCTCCACTA CCGGAACCGA GAGCGCTTTG CCACAATCAA ATCAGCATCT 1320

TTGGTTACAA GACAGATCCA TGAGCATGAG CAGGAGAACG AGCTGCGGGA ACAGATGTCA 1380

GGATATAAGC GGATGCGGCG CCAGCACCAG AAGCAGCTGA TCGCCCTGGA GAACAAGTTG 1440

AAGGCCGAGA TGGACGAGCA CCGCCTCAAG CTGCAGAAGG AGGTGGAGAC ACACGCCAAC 1500

AACTCGTCCA TTGAGCTGGA GAAGCTGGCC AAGAAGCAAG TGGCTGTGAT GGAGAAGGAG 1560

GCAAAGGCAG CTGCAGCAGA TGAAAAGAAA TTCCAGCAAC AGATTTTGGC TCAGCAAAAG 1620

AAAGACCTGG CGACCTTTTT AGAAAGTCAG AAGAAACAAT ACAAGCTTTG CAAGGAAAAG 1680

ATTAAAGAGG CAAGAAACAT TTTTGGGGCT AAAGGGGACC ACAGCACACC CAAGAAAGAG 1740

AAACAAGAAA GGATATCCAA ACACAAAGAG AACCTGCAGC ACACACAGGC TGAAGAGGAG 1800

GCCCAGCTTC TCAGCCAGCA GAGACTCTAC TACGACAAAA ACTGCCGTTT CTTCAAGAGA 1860

AAAACGATGA TCAAGAGGCA CGAGATGGAG CAGCAGAACA TTCGGGAAGT ATGGCACTCC 1920

TCACTTCCTC TCCCAGCCTT TTTTAACTGC CTTAGCTTCA ACTGTGAAAA ATGTAAGAAA 1980

ATAGGTTTTG GGAAATGGTT TTTCCTGCAG CTCACCAGAC CTGAGCCCGA GAACCAGCTG 2040

GAGTACAACA AGCGGCGCGA GCGGGAGCTG CACAGGAAGC ATTTCATGGA GCTCCGGCAG 2100

CAACCAAAGA ACCTGAAGGC TATGGAAATG CAGATCAAAA AGCAGTTCCA GGACACATGC 2160

AAAGTGCAAA CTAAGCAGTA CAAAGCACTG AAGAATCACC AGCTGGAAGT AACTCCAAAG 2220

AGTGAGCACA AGACAATTCT GAAGAGCCTG AAGGACGAGC AGACACGGAA GCTCGCCATC 2280

CTGGCCGAGC AGTACGAGCA GAGCATCAAT GAGATGATGG CCTCGCAGGC GCTCCGGCTG 2340

GACGAGGCCC AGGAAGCAGA ATGCCAAGCC CTGAGACTGC AACTCCAGCA GGAGATGGAG 2400

CTGCTCAACG CCTACCAGAG CAAAATAAAG ATGCAGACAG AAGCACAGCA CGAAAGGGAA 2460

CTCCAGAAGC TGGAGCAACG GGTGTCGCTG CGCAGGGCAC ACCTGGAACA GAAGATTCGA 2520

AGAAGGAGCT CGTCCGCCCT CCAGAAGGAA CGCAAGCGAG AGGATCTAGT TTTCTGTTTG 2580

GAAAGGCAGG AGCGAGAGAT TGAGACGTTT GACATGGAGA GCCGGATGGG CTTTGGGAAT 2640

TTGGTCTCAT TTGAGTTTCT CAAGGAGGAC TATAGATGA 2679

Domain Profile

S: 4     leeigkGalgkvylarekktgelvaikkinlekq...ekleelqkeisvlkklkhpnive  60

         l+eig+G++g+vy a++ +t+e+va+kk++++ +   ek+++++ke+++l++lkhpn +e

Q: 27    LHEIGHGSFGAVYFATNSHTNEVVAVKKMSYSGKqtnEKWQDIIKEVKFLQQLKHPNTIE  86

         689****************************988899***********************

S: 61    ylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkvi  120

         y +++lke++ wlvmey+  Gs+sdl++ ++k++l+E +ia+i++++l++L+ylHs+  i

Q: 87    YKGCYLKEHTAWLVMEYCL-GSASDLLE-VHKKPLQEVEIAAITHGALQGLAYLHSHCRI  144

         ******************7.********.*******************************

S: 121   HrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgYdek  180

         Hrdika+niLlte g+VkL+dfg+a+ ++      +++vgtpy      ++    g +

Q: 145   HRDIKAGNILLTEPGQVKLADFGSASIVSP----ANSFVGTPYCEQQFSLN-GCPGLTWN  199

         *************************99999....69******976555555.48899999

S: 181   aDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekclqk  240

         + i +l +++  l e++pP++++++++al++i++n++p+l+s+ ++s++f+ fv+ clqk

Q: 200   IKIIGLSVMTTALTERKPPLFNMNAMSALYHIAQNDSPRLQSN-EWSDSFRGFVDYCLQK  258

         99**************************************888.****************

S: 241   npekRpsasellkhkFl  257

          p++Rps+++ll+h F+

Q: 259   IPQERPSSTDLLRHDFV  275

         ***************97

Domain Sequence
(FASTA)

LHEIGHGSFG AVYFATNSHT NEVVAVKKMS YSGKQTNEKW QDIIKEVKFL QQLKHPNTIE 60

YKGCYLKEHT AWLVMEYCLG SASDLLEVHK KPLQEVEIAA ITHGALQGLA YLHSHCRIHR 120

DIKAGNILLT EPGQVKLADF GSASIVSPAN SFVGTPYCEQ QFSLNGCPGL TWNIKIIGLS 180

VMTTALTERK PPLFNMNAMS ALYHIAQNDS PRLQSNEWSD SFRGFVDYCL QKIPQERPSS 240

TDLLRHDFV 249

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005739	; C:mitochondrion
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0031572	; P:G2/M transition DNA damage checkpoint
GO:0000165	; P:MAPK cascade
GO:0046329	; P:negative regulation of JNK cascade
GO:0046330	; P:positive regulation of JNK cascade
GO:0043507	; P:positive regulation of JUN kinase activity
GO:0046777	; P:protein autophosphorylation

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013