EKS-TAG-00196

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00196

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TTK	444.0	1.7E-133	209	475	267

Status

Unreviewed

Ensembl Protein

ENSTGUP00000012948

UniProt Accession

H0ZQQ8;

Protein Name

Protein Synonyms/Alias

Gene Name

TTK

Gene Synonyms/Alias

TTK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000012578	ENSTGUP00000012948	ENSTGUT00000013096

Organism

Taeniopygia guttata

Functional Description

Protein Length

545

Protein Sequence
(FASTA)

SLQEKTALQL QMLDEGSSET ATNSTVTLKT KVDASLVTKR AENKVQHLEL KIPEPRSLDS 60

QQQPSSFGES YKKQLEQIKL NCVNARKKMT TQEVSQESCY GEGKQTNLEQ SGHPVSRRLS 120

PSDAVLKKNH PSHVYGTPST TTSNDYMACF STPVIKDKFV PGCQISTPYS QFPYYLPHTP 180

ATPFQNQVGL QVPASVPSHE CLVINGRVYT VLKQIGSGGS SKVFQVLNDK KQLYAVKYVN 240

LEEADQQTVE SYKNEIAHLS KLQQHSDKII RLYSYEITDQ HIYMVMECGN IDLNSWLKKK 300

KKMDPLERKS YWKNMLEAVH TIHEHGIIHS DLKPANFLIV DGMLKLIDFG IANQMQPDVT 360

SIIKDSQAGT MNYMPPEAIE DRSSYGENGK PRSKISPKSD VWSLGCILYC MTYGRTPFQH 420

ITSHINKMHA IVDPNYEIGF PDIAEKDLQD VLKRCLVRNP KERISVSELL VHPYVQIQSH 480

CQTGVPNAKG ATEEMKRILG QLVGLNSPNS ISRAARTLYE QCNSGKTLDV SAFAKPGSQK 540

TWTTK 545

Nucleotide Sequence
(FASTA)

TCCTTACAAG AAAAAACAGC TTTACAGTTG CAGATGTTGG ATGAGGGCAG CTCAGAAACA 60

GCTACCAATT CAACTGTAAC TCTCAAAACC AAAGTGGATG CAAGTCTTGT GACAAAAAGA 120

GCAGAAAATA AAGTTCAGCA TCTGGAGCTG AAGATACCAG AGCCGAGGAG TCTGGACAGT 180

CAACAGCAAC CATCTAGTTT TGGAGAAAGC TATAAAAAGC AGTTGGAACA GATTAAACTA 240

AACTGTGTTA ATGCCAGAAA AAAAATGACA ACTCAAGAAG TGTCACAGGA AAGCTGCTAT 300

GGAGAGGGAA AACAAACAAA CCTCGAACAG TCTGGTCATC CTGTTTCAAG ACGATTATCA 360

CCATCAGATG CTGTTTTGAA GAAAAATCAC CCATCACACG TTTATGGAAC ACCAAGCACC 420

ACCACATCTA ATGATTATAT GGCCTGTTTC AGCACACCAG TCATAAAGGA CAAGTTTGTA 480

CCAGGATGTC AAATTTCTAC TCCTTACAGC CAGTTCCCTT ATTATTTACC ACATACTCCA 540

GCAACTCCAT TTCAAAATCA AGTTGGCTTG CAGGTTCCAG CTTCTGTACC TTCGCATGAA 600

TGCCTTGTCA TCAATGGAAG AGTTTATACA GTGTTAAAGC AAATAGGTAG TGGAGGCTCA 660

AGTAAGGTAT TTCAAGTACT GAATGACAAG AAGCAGCTGT ATGCTGTCAA ATATGTGAAT 720

CTAGAGGAAG CTGATCAACA GACTGTTGAG AGCTATAAGA ATGAAATTGC TCATTTGAGT 780

AAACTGCAGC AACATAGTGA TAAGATCATC CGCCTTTATA GCTATGAAAT TACTGATCAA 840

CATATCTACA TGGTAATGGA GTGTGGAAAT ATTGATCTCA ATAGCTGGCT TAAAAAGAAA 900

AAAAAGATGG ATCCATTGGA ACGAAAGAGC TATTGGAAAA ATATGCTGGA AGCTGTTCAC 960

ACAATCCATG AACATGGCAT TATTCACAGT GATCTGAAAC CAGCAAACTT TCTGATAGTT 1020

GATGGAATGT TAAAACTAAT TGACTTTGGT ATTGCAAACC AAATGCAGCC AGATGTGACA 1080

AGTATCATTA AAGATTCTCA GGCTGGCACA ATGAATTACA TGCCTCCTGA AGCAATAGAA 1140

GATAGGTCTT CCTATGGAGA AAATGGCAAG CCTCGTTCTA AGATAAGTCC CAAAAGCGAT 1200

GTGTGGTCAC TGGGCTGCAT TTTGTACTGT ATGACATATG GAAGGACTCC ATTTCAGCAT 1260

ATAACAAGTC ACATCAATAA AATGCATGCT ATTGTTGATC CAAATTATGA AATAGGGTTC 1320

CCAGATATTG CTGAGAAGGA TCTTCAGGAT GTGCTGAAGC GCTGCTTAGT AAGAAATCCT 1380

AAAGAGAGAA TTTCTGTTTC GGAGTTGCTG GTACATCCCT ATGTTCAAAT TCAAAGTCAC 1440

TGTCAAACAG GTGTCCCAAA TGCAAAAGGA GCAACAGAGG AAATGAAACG TATCCTTGGC 1500

CAGCTTGTTG GCTTGAATTC TCCCAATTCT ATTTCTAGAG CTGCAAGGAC TTTATATGAA 1560

CAGTGCAACA GTGGTAAAAC TCTTGATGTA TCAGCATTTG CAAAACCTGG GAGTCAAAAA 1620

ACGTGGACAA CAAAA 1635

Domain Profile

S: 1     yeilkklGsGGsskvfkvksekkrvyalkvvdleaaddqtidgykneielleklqdqs.k  59

         y++lk++GsGGsskvf+v+++kk+ ya+k+v+le+ad+qt+++yknei+ l klq++s k

Q: 209   YTVLKQIGSGGSSKVFQVLNDKKQLYAVKYVNLEEADQQTVESYKNEIAHLSKLQQHSdK  268

         99********************************************************9*

S: 60    virlydyeledsllylvmecGdidlnkilkkkksiepdyelvsyykemleavkvihqhGi  119

         +irly ye++d+++y+vmecG+idln++lkkkk ++p  e++sy+k+mleav++ih+hGi

Q: 269   IIRLYSYEITDQHIYMVMECGNIDLNSWLKKKKKMDP-LERKSYWKNMLEAVHTIHEHGI  327

         *************************************.9*********************

S: 120   vhsdlkPanfllvdGilklidfGianavaedttsivkesqvGtvnylaPealkdmsssqs  179

         +hsdlkPanfl+vdG+lklidfGian++++d tsi+k+sq+Gt+ny++Pea++d ss

Q: 328   IHSDLKPANFLIVDGMLKLIDFGIANQMQPDVTSIIKDSQAGTMNYMPPEAIEDRSSY--  385

         ******************************************************9877..

S: 180   sereaekskikvsrksdvwslGcilylllygktPfgsirnqvskllaiinPdveiefPei  239

            e++k+++k+s+ksdvwslGcily ++yg+tPf++i + ++k++ai++P+ ei fP+i

Q: 386   --GENGKPRSKISPKSDVWSLGCILYCMTYGRTPFQHITSHINKMHAIVDPNYEIGFPDI  443

         ..89********************************************************

S: 240   tsniekslvellkaclkrnPkkrisvdellsspfv  274

         +   ek+l+++lk cl+rnPk+risv+ell +p+v

Q: 444   A---EKDLQDVLKRCLVRNPKERISVSELLVHPYV  475

         *...*****************************96

Domain Sequence
(FASTA)

YTVLKQIGSG GSSKVFQVLN DKKQLYAVKY VNLEEADQQT VESYKNEIAH LSKLQQHSDK 60

IIRLYSYEIT DQHIYMVMEC GNIDLNSWLK KKKKMDPLER KSYWKNMLEA VHTIHEHGII 120

HSDLKPANFL IVDGMLKLID FGIANQMQPD VTSIIKDSQA GTMNYMPPEA IEDRSSYGEN 180

GKPRSKISPK SDVWSLGCIL YCMTYGRTPF QHITSHINKM HAIVDPNYEI GFPDIAEKDL 240

QDVLKRCLVR NPKERISVSE LLVHPYV 267

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013