EKS-TAG-00229

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAG-00229

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	461.1	9.3E-139	4	286	283

Status

Unreviewed

Ensembl Protein

ENSTGUP00000013570

UniProt Accession

H0ZSH4;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL1

Gene Synonyms/Alias

CDKL1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000013175	ENSTGUP00000013570	ENSTGUT00000013725

Organism

Taeniopygia guttata

Functional Description

Protein Length

351

Protein Sequence
(FASTA)

MERYEKLGKV GQGSYGVVFK CRNKDTGQIV AIKKFLESEE DPVIRKIALR EIRMLKQLKH 60

PNLVNLLEVI TWQTLQAVNF CHKHNVRSDM DSHLAVVPEY LVKSITWQTL QAVNFCHKHN 120

CIHRDVKPEN ILITKHSVIK LCDFGFARIL TGPSDYYTDY VATRWYRSPE LLVGDTQYGP 180

PVDVWAIGCV FAELLSGAPL WPGRSDADQL YLIRRTLGDL IPRHQQVFST NQFFSGVRIP 240

DPESMEPLEM KFPNISYSAL ALMKGCLRMD PAERQSCEQL LQQPYFDSFR AAAELGREHE 300

KSSRKAARLT RKHVPGLQHL PQLTCSKVLP ALDSKKNCCK TRKSNYHFPN I 351

Nucleotide Sequence
(FASTA)

ATGGAGCGCT ACGAGAAGCT GGGCAAGGTC GGCCAGGGCT CCTACGGCGT CGTTTTCAAG 60

TGCCGCAACA AAGACACGGG GCAGATTGTG GCCATCAAGA AGTTCCTGGA GTCCGAGGAG 120

GACCCGGTGA TCCGGAAGAT CGCGCTGAGG GAGATCCGCA TGCTCAAGCA ACTCAAACAC 180

CCCAACCTGG TGAACCTGCT GGAGGTCATA ACCTGGCAGA CCCTGCAGGC TGTGAACTTC 240

TGCCATAAAC ACAATGTGAG GTCTGATATG GACTCACACT TGGCTGTAGT GCCAGAGTAC 300

CTGGTGAAGA GCATAACCTG GCAGACCCTG CAGGCTGTGA ACTTCTGCCA TAAACACAAT 360

TGCATCCACC GGGATGTAAA GCCAGAGAAC ATCCTGATAA CAAAGCACTC GGTCATCAAA 420

CTCTGTGACT TCGGATTCGC TCGAATACTG ACCGGTCCCA GTGACTACTA CACCGACTAC 480

GTGGCCACCC GGTGGTACCG CTCCCCGGAG CTGCTGGTGG GGGACACCCA GTACGGGCCC 540

CCCGTGGACG TGTGGGCCAT CGGCTGCGTC TTCGCCGAGC TGCTCTCGGG GGCGCCGCTG 600

TGGCCGGGCA GGTCGGACGC GGACCAGCTG TACCTGATCC GCAGAACCCT GGGGGATCTC 660

ATTCCCAGGC ACCAGCAAGT GTTCAGCACC AACCAGTTCT TCAGTGGGGT AAGAATTCCA 720

GACCCAGAGA GCATGGAACC ACTGGAAATG AAATTCCCCA ATATTTCATA CTCTGCACTG 780

GCTCTCATGA AGGGCTGCCT TCGGATGGAC CCTGCGGAGA GGCAGAGCTG TGAGCAGCTG 840

CTGCAGCAGC CCTATTTTGA CAGCTTCAGG GCGGCAGCAG AGCTGGGCAG AGAGCACGAG 900

AAGAGCTCTC GGAAAGCAGC CAGGCTGACT CGGAAGCACG TGCCAGGGTT ACAGCACCTG 960

CCTCAGCTGA CCTGCAGCAA AGTTCTCCCA GCTTTGGACA GCAAGAAGAA CTGCTGCAAG 1020

ACAAGGAAAT CAAACTACCA CTTCCCAAAC ATCTGA 1056

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yeklgkvG+GsyGvv+kcrnkdtgqivaikkflese+d++++kialrei++lkqlkh+nl

Q: 4     YEKLGKVGQGSYGVVFKCRNKDTGQIVAIKKFLESEEDPVIRKIALREIRMLKQLKHPNL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllev+  +  l  v    +++v  +++ +   v+e lvk+i++q+l+a++fchk+n+i

Q: 64    VNLLEVITWQT-LQAVNFCHKHNVRSDMDSHLAVVPEYLVKSITWQTLQAVNFCHKHNCI  122

         *******8765.55554445799*************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenili+k++v+klcdfGfar+l++p+d+ytdyvatrwyr+pellvgdt+yG++v

Q: 123   HRDVKPENILITKHSVIKLCDFGFARILTGPSDYYTDYVATRWYRSPELLVGDTQYGPPV  182

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGc++aell+G pl+pg+sd dqly+ir+tlG+liprhq++fs+n++f+Gv++p++

Q: 183   DVWAIGCVFAELLSGAPLWPGRSDADQLYLIRRTLGDLIPRHQQVFSTNQFFSGVRIPDP  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         e++e+le k+p++++++l l+k+cl++dpaer sce+ll+++yf

Q: 243   ESMEPLEMKFPNISYSALALMKGCLRMDPAERQSCEQLLQQPYF  286

         ******************************************99

Domain Sequence
(FASTA)

YEKLGKVGQG SYGVVFKCRN KDTGQIVAIK KFLESEEDPV IRKIALREIR MLKQLKHPNL 60

VNLLEVITWQ TLQAVNFCHK HNVRSDMDSH LAVVPEYLVK SITWQTLQAV NFCHKHNCIH 120

RDVKPENILI TKHSVIKLCD FGFARILTGP SDYYTDYVAT RWYRSPELLV GDTQYGPPVD 180

VWAIGCVFAE LLSGAPLWPG RSDADQLYLI RRTLGDLIPR HQQVFSTNQF FSGVRIPDPE 240

SMEPLEMKFP NISYSALALM KGCLRMDPAE RQSCEQLLQQ PYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013