EPS-TAG-00011

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-TAG-00011

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	144.8	1.5E-42	137	281	145

Status

Unreviewed

Ensembl Protein

ENSTGUP00000013909

UniProt Accession

H0ZTG3;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP27

Gene Synonyms/Alias

DUSP27;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000013509	ENSTGUP00000013909	ENSTGUT00000014068

Organism

Taeniopygia guttata

Functional Description

Protein Length

1146

Protein Sequence
(FASTA)

MASGRDSDSE PALPEEEEEE EGPDVKAVQA HYLRSPSPSR YSVISDTNTE SIFMEPIHLS 60

SAVAAKQIIS EELKTKDVRV DSVCPRMLES AQQLMVEDLY NRVKEKIDDT SLFNTPCVMD 120

LQRALVKDRL ETPRDAVDEV WPNVFIAEKS VAVNKSRLKR LGITHVLNAA HGTGVYTGAN 180

FYNGLNIQYL GIEVDDFPDT DISKHFRPAA EFLDEALLTY RGRILVSSEM GISRSAVLVA 240

AYLMIYHHMT ILEALMTLRK KRAIYPNDGF LKQLRELNEQ LLEERELERS GDEDVTPSQT 300

GDSGSIKGAK AHSITVEEED TSSILGSFMS SSSVEKTSWV SKHSTLITEE EEEQLYEEWR 360

RKQGLSEKEA GVHHERKTSP KASGSGEDQS DEDVEWRIHD WQRRNEKYQM AGTAREENDE 420

CSIRGRPYPS GEFSDVESVS SFEIRTLKKQ LEASSFSRMR RSRTGSMSSE STWDMWNQRL 480

LEIEEEAAQR YHSRNKTRGE RQSPETGRKE RDVDEESVFS DSSCSSFYNF CQKNKDKLTP 540

LERWKVKRIQ FGFHKKDLEP SSAPSPAEDG SQAGKSLSDI DLTAYQAWKM KRQKKVGSES 600

SKEEFLEFAK TEDSASAKKK QRRVELLERS KKILEESQSM CSWETESTMS GSIPLSAFWA 660

SAPSASGADD AASALSMQTN HSSLSQTRSC TGAMQLQMPN IPLPNLPVGP GDTISMASIQ 720

NWIANVVSET IAQKQNEILM LSRPSSAMAS LSGDLGRRAD DDKASLLSAQ SGSSLAASQL 780

HQQDLRRAES QSVLSCNTSV SARTEGATSN MKMTQTSKPL YSLFADDVDL KKLRKKEKEM 840

QMEMREKMSD YQIEKVIRDN KRSTLFKKKV TKAEENETED DRESTTNSHR RPLQADFDRT 900

DAVFDLSSRP ATSGALKSEV DTDISKWLNG LKAEREPPSY YDQSEKAREK YSRSSKVRQM 960

DSETSSYRFC RSQRKEQDSC SSYESTGDSM RTTSRFSSAS AKEDKKMYKF TRSRVSETSS 1020

RGNSPELHVF SQSPEPPFES ESPEPSTQSR VRAHHVEACE EEARSDVSEC GAKRKFTQSF 1080

SKSEEDGKKE AKVEQSEERF ASRKVSQYRR STRKEEEEEM DDDAIIAAWR SRLEETTAKL 1140

QRRREE 1146

Nucleotide Sequence
(FASTA)

ATGGCCAGCG GCAGAGATTC GGACAGCGAG CCGGCGCTGC CCGAGGAGGA GGAGGAGGAG 60

GAGGGCCCGG ACGTGAAGGC CGTGCAGGCC CATTACCTGC GCAGCCCCTC GCCCAGCCGG 120

TATTCAGTGA TATCAGACAC TAATACAGAG AGCATCTTCA TGGAGCCGAT CCATCTGTCA 180

TCTGCTGTGG CTGCCAAACA AATCATCAGT GAAGAGCTGA AGACAAAGGA CGTCAGGGTA 240

GACTCAGTGT GTCCCAGGAT GTTGGAGTCT GCGCAGCAGC TGATGGTGGA AGACCTGTAC 300

AACCGAGTTA AGGAAAAGAT TGATGACACC AGCTTGTTTA ACACGCCGTG TGTGATGGAC 360

TTGCAGAGGG CACTTGTGAA GGACAGGCTG GAGACCCCCA GGGACGCTGT GGATGAAGTC 420

TGGCCTAATG TCTTCATAGC AGAAAAAAGT GTTGCAGTAA ACAAAAGCCG TTTGAAGAGA 480

CTGGGCATCA CCCATGTCCT GAATGCAGCT CATGGCACAG GTGTCTACAC AGGTGCAAAT 540

TTCTACAATG GTCTCAATAT CCAGTACCTA GGCATTGAAG TGGATGATTT TCCAGATACA 600

GATATCTCCA AACACTTCCG CCCAGCTGCA GAGTTCCTTG ACGAAGCCCT GCTGACTTAC 660

AGAGGCAGAA TCCTTGTCAG CAGTGAGATG GGGATCAGCC GCTCAGCTGT GCTGGTGGCT 720

GCCTACCTGA TGATCTACCA CCATATGACC ATTCTGGAGG CTCTGATGAC CCTGAGGAAG 780

AAACGTGCCA TCTACCCCAA CGACGGCTTC CTGAAGCAGC TGCGGGAGCT CAATGAGCAG 840

CTGTTGGAGG AGCGAGAGCT GGAGCGTTCT GGAGATGAGG ATGTGACTCC AAGCCAAACT 900

GGGGACTCAG GGAGCATCAA GGGAGCCAAA GCTCACTCCA TCACAGTAGA AGAAGAGGAC 960

ACCAGCAGCA TTCTGGGTAG TTTTATGAGC TCCTCATCAG TGGAAAAAAC TAGCTGGGTT 1020

TCCAAACACT CCACCCTGAT CACTGAGGAG GAAGAGGAAC AATTGTATGA GGAATGGAGG 1080

AGGAAACAAG GCCTATCTGA AAAGGAAGCA GGAGTTCACC ATGAAAGAAA AACATCTCCA 1140

AAAGCATCTG GATCAGGAGA GGATCAATCT GATGAGGATG TGGAATGGAG GATCCATGAC 1200

TGGCAGCGCA GAAATGAGAA ATACCAGATG GCGGGTACAG CCAGGGAGGA GAATGATGAA 1260

TGCAGCATTA GAGGAAGACC TTACCCATCA GGTGAATTCA GTGATGTTGA GAGTGTGAGC 1320

AGTTTTGAGA TTCGAACCCT AAAAAAACAG CTGGAAGCCA GTAGCTTTAG CAGGATGAGG 1380

AGGAGCCGCA CAGGCTCTAT GTCTTCTGAG AGCACCTGGG ACATGTGGAA TCAGAGGCTT 1440

CTGGAGATTG AGGAAGAAGC TGCTCAGAGG TATCATTCTA GGAATAAAAC CCGTGGGGAG 1500

AGACAATCCC CAGAAACGGG AAGAAAGGAG AGGGATGTGG ATGAGGAGAG TGTGTTTTCA 1560

GACTCCTCCT GTAGCTCCTT CTACAATTTC TGCCAAAAGA ACAAGGACAA GTTGACTCCT 1620

CTAGAAAGGT GGAAGGTCAA GAGGATCCAG TTTGGCTTTC ACAAGAAGGA TTTAGAACCA 1680

TCATCTGCAC CATCTCCAGC AGAGGATGGC AGTCAGGCAG GGAAGAGTTT GTCAGATATT 1740

GATCTGACTG CTTACCAGGC TTGGAAGATG AAGCGGCAGA AGAAGGTGGG CAGTGAAAGC 1800

AGCAAGGAGG AATTTCTGGA ATTTGCCAAA ACTGAGGATT CTGCTTCAGC TAAAAAGAAG 1860

CAGAGGCGTG TAGAACTCCT TGAACGTTCA AAGAAAATTT TAGAAGAAAG CCAGTCCATG 1920

TGCAGCTGGG AGACAGAGAG CACAATGAGT GGGAGTATTC CCCTGTCAGC TTTCTGGGCT 1980

TCAGCACCTT CTGCAAGCGG TGCCGACGAT GCAGCTTCTG CCCTGAGCAT GCAGACAAAT 2040

CATTCATCTT TGTCACAGAC CAGGAGTTGT ACTGGAGCAA TGCAGCTGCA AATGCCAAAT 2100

ATACCCCTTC CCAATCTCCC AGTTGGCCCA GGTGACACAA TATCTATGGC AAGCATTCAG 2160

AACTGGATCG CTAACGTGGT CAGTGAAACC ATTGCTCAAA AGCAAAATGA GATCCTGATG 2220

CTGTCCCGTC CATCGTCTGC CATGGCCTCC CTGTCAGGAG ACCTTGGCAG GCGTGCAGAT 2280

GATGACAAGG CTTCTCTTCT CAGTGCTCAG AGTGGCTCAT CCCTCGCTGC CTCTCAGCTC 2340

CACCAGCAGG ACCTGCGCAG GGCTGAGTCT CAGTCTGTGC TGTCTTGCAA CACCTCCGTG 2400

AGTGCAAGGA CAGAAGGGGC TACTTCAAAC ATGAAGATGA CCCAGACAAG CAAACCACTG 2460

TACAGCCTCT TTGCTGATGA TGTTGACCTA AAGAAACTCA GGAAGAAGGA GAAGGAGATG 2520

CAAATGGAAA TGAGAGAAAA AATGTCAGAC TATCAAATTG AAAAGGTGAT CCGAGACAAT 2580

AAACGCAGCA CTTTATTCAA AAAAAAGGTG ACCAAAGCAG AGGAAAATGA AACAGAAGAT 2640

GACAGAGAGA GTACAACAAA CAGCCACAGG CGTCCCTTGC AAGCAGATTT TGACAGAACT 2700

GATGCAGTCT TCGATCTGTC TAGTCGACCT GCAACCTCAG GTGCACTGAA GTCAGAGGTA 2760

GATACTGATA TTTCCAAGTG GCTAAATGGC CTGAAAGCAG AAAGAGAACC ACCATCATAT 2820

TATGATCAGT CTGAGAAAGC TAGAGAGAAA TACAGCAGAT CATCCAAAGT TAGACAGATG 2880

GATTCTGAGA CATCCAGTTA CAGATTCTGC AGATCCCAAA GAAAAGAGCA AGATAGCTGT 2940

TCTTCCTATG AGTCAACTGG AGATTCAATG AGAACCACGT CAAGATTTTC CTCTGCTTCT 3000

GCAAAAGAGG ACAAAAAGAT GTACAAGTTC ACAAGGTCCA GGGTCAGTGA GACAAGTTCC 3060

AGAGGAAACA GCCCAGAGCT GCATGTTTTC AGCCAGTCAC CTGAACCACC CTTTGAGTCT 3120

GAATCCCCCG AACCATCTAC ACAGAGCCGA GTTAGAGCTC ATCATGTGGA GGCATGTGAA 3180

GAGGAGGCCA GGTCAGACGT GTCAGAATGT GGAGCAAAGA GAAAGTTCAC CCAGAGCTTT 3240

TCAAAGTCTG AAGAGGATGG AAAGAAGGAG GCAAAAGTGG AGCAAAGTGA AGAAAGGTTT 3300

GCATCTAGGA AGGTCTCTCA GTACAGGCGA AGCACACGTA AAGAAGAGGA AGAAGAGATG 3360

GATGATGATG CCATTATTGC TGCTTGGAGA AGCCGACTAG AAGAAACTAC AGCAAAGCTG 3420

CAGCGGAGAA GGGAAGAGTG A 3441

Domain Profile

S: 2     vteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvd  61

         v+e++p+++++++ +a+++  L++lgit+v+na++++    ++ +++   +i+y++i+vd

Q: 137   VDEVWPNVFIAEKSVAVNKSRLKRLGITHVLNAAHGTGV-YTGANFYNGLNIQYLGIEVD  195

         89*********************************8765.7999****************

S: 62    Dsdvtdllqyfdeaaefidea.kekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAi  120

         D ++td++++f++aaef+dea  + +g++lv +++G+sRSa+lv aYLm+++++++ +A+

Q: 196   DFPDTDISKHFRPAAEFLDEAlLTYRGRILVSSEMGISRSAVLVAAYLMIYHHMTILEAL  255

         *********************8999***********************************

S: 121   eavkrkrpsiepnegfleQLlelekkl  147

         +++++kr +i+pn+gfl+QL+el+++l

Q: 256   MTLRKKR-AIYPNDGFLKQLRELNEQL  281

         *******.***************9987

Domain Sequence
(FASTA)

VDEVWPNVFI AEKSVAVNKS RLKRLGITHV LNAAHGTGVY TGANFYNGLN IQYLGIEVDD 60

FPDTDISKHF RPAAEFLDEA LLTYRGRILV SSEMGISRSA VLVAAYLMIY HHMTILEALM 120

TLRKKRAIYP NDGFLKQLRE LNEQL 145

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR020417	; Atypical_DUSP.
IPR020405	; Atypical_DUSP_famA.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR000387	; Tyr/Dual-specificity_Pase.

Pfam

PF00782

; DSPc; 1.

SMARTs

SM00195

; DSPc; 1.

Prosites

PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

PR01908	; ADSPHPHTASE.
PR01909	; ADSPHPHTASEA.

Created Date

20-Feb-2013