EPS-TAG-00032

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-TAG-00032

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	169.6	9.9E-50	317	502	186

Status

Unreviewed

Ensembl Protein

ENSTGUP00000015134

UniProt Accession

H0ZWY3;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1G

Gene Synonyms/Alias

PPM1G;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTGUG00000014753	ENSTGUP00000015134	ENSTGUT00000015370

Organism

Taeniopygia guttata

Functional Description

Protein Length

542

Protein Sequence
(FASTA)

MGAYLSQPNT VKSSGDGAGL GPRPLHFGFS AMQGWRVSME DAHNCIPELD SETAMFSVYD 60

GHGGEEVALY CAKYLPEIIK DQKAYKEGQL QKALEDAFLA IDAKLTTEEV IKELSQMAGR 120

PQDDEDEKEK VADEDDVDNE EAALLHEEAT MTIEELLTRY GQNCTKNLRA KSGTGKQHDG 180

ESNMNGEADP GELPDHKERK NGKPDEEITG ISSTSDKASA GGNSPALQKP ELGKGDEAAG 240

PSCSSTGKPQ RTTKSKFFED SEDESDEVEE EEEDSEECSE DEDGYSSGEA ENEDDEDDTE 300

EAEEDEDEEE EMLLPGMEGK EEPGSDSGTT AVVALIRGKQ LIVANAGDSR CVVSEGGKAV 360

DMSYDHKPED EVELARIKNA GGKVTMDGRV NGGLNLSRAI GDHFYKRNKN LPPEEQMISA 420

LPDIKVLTIN DDHDFMVIAC DGIWNVMSSQ EVVDFIQSKI TQKDENGVLR PLSSIVEELL 480

DQCLAPDTSG DGTGCDNMTC IIISFKPRNT HPPAESGKRK LGEAMAPAEE NGGDSTKKSK 540

LE 542

Nucleotide Sequence
(FASTA)

ATGGGCGCCT ATTTGTCGCA GCCCAACACG GTGAAGAGCT CCGGGGACGG CGCCGGGCTC 60

GGGCCGCGCC CGCTGCACTT CGGGTTCAGC GCCATGCAGG GATGGCGCGT CTCCATGGAG 120

GATGCCCACA ACTGCATTCC TGAGCTGGAC AGTGAAACAG CCATGTTCTC TGTCTACGAT 180

GGACACGGAG GAGAAGAAGT TGCCCTGTAC TGTGCCAAGT ACCTCCCTGA GATCATCAAA 240

GACCAGAAGG CCTACAAGGA AGGCCAATTG CAAAAGGCCC TGGAAGATGC ATTCTTGGCC 300

ATTGATGCCA AGCTCACCAC AGAGGAGGTG ATTAAGGAGC TCTCTCAAAT GGCTGGGCGG 360

CCACAGGACG ATGAAGATGA GAAGGAGAAA GTTGCTGATG AAGATGATGT GGATAATGAG 420

GAAGCTGCTC TTCTGCACGA AGAAGCCACA ATGACCATCG AGGAGCTTCT CACACGTTAC 480

GGACAAAACT GCACCAAGAA CCTCAGAGCC AAGTCTGGGA CAGGCAAGCA GCATGATGGG 540

GAGTCAAATA TGAATGGAGA GGCTGACCCA GGGGAGCTTC CCGACCACAA GGAGAGGAAG 600

AACGGGAAGC CAGACGAAGA AATCACGGGT ATTTCCTCCA CCTCAGACAA AGCCAGCGCT 660

GGAGGCAACA GCCCTGCTCT GCAGAAGCCT GAACTAGGCA AAGGTGACGA GGCCGCCGGG 720

CCCTCCTGCT CCTCTACGGG AAAGCCCCAG CGCACAACCA AATCCAAATT TTTTGAGGAC 780

AGTGAGGATG AGTCAGATGA GGTTGAGGAA GAGGAGGAAG ACAGTGAGGA ATGTAGTGAG 840

GATGAGGACG GTTACAGCAG TGGAGAGGCA GAGAATGAAG ATGATGAAGA TGACACGGAA 900

GAAGCAGAGG AGGATGAGGA TGAAGAGGAG GAAATGTTGT TACCGGGCAT GGAGGGAAAG 960

GAGGAGCCTG GCTCAGACAG TGGGACCACG GCTGTGGTGG CGCTCATCCG TGGCAAGCAG 1020

CTGATCGTGG CCAACGCCGG GGACTCGCGC TGCGTCGTGT CAGAGGGCGG CAAGGCTGTC 1080

GACATGTCCT ACGACCACAA GCCAGAGGAT GAGGTGGAGC TGGCCAGGAT AAAGAATGCT 1140

GGTGGCAAGG TCACCATGGA CGGAAGGGTG AACGGCGGCC TCAACCTCTC CAGGGCCATC 1200

GGGGATCACT TCTACAAGCG GAACAAGAAC CTCCCTCCAG AAGAGCAGAT GATCTCTGCC 1260

TTGCCTGACA TCAAAGTGCT GACAATAAAC GATGACCACG ACTTCATGGT CATTGCCTGT 1320

GATGGAATCT GGAACGTGAT GAGCAGCCAG GAAGTGGTGG ATTTCATCCA GTCGAAGATC 1380

ACCCAAAAGG ATGAGAATGG AGTCCTGCGG CCACTCTCCT CCATTGTAGA AGAGCTGCTG 1440

GATCAGTGCT TGGCTCCAGA CACCTCCGGG GATGGCACCG GCTGTGATAA CATGACCTGC 1500

ATCATTATCA GCTTCAAACC CCGTAACACA CACCCACCTG CTGAGAGTGG GAAGCGGAAA 1560

CTAGGGGAGG CAATGGCACC AGCAGAGGAG AACGGTGGGG ACAGCACCAA GAAGTCCAAA 1620

CTGGAGTAG 1629

Domain Profile

S: 93    leeksldidksGstavvalikdsklyvanvGdSravLcrngkavelssdHkpsredEleR  152

         +e k++  + sG+tavvali++++l+van+GdSr+v + +gkav +s dHkp+ e El+R

Q: 317   MEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEGGKAVDMSYDHKPEDEVELAR  376

         4444445566**************************************************

S: 153   ieeaggsvilkdgaRvlGvLavsRalGdlylk.........pyvtpePevtshrltsede  203

         i++agg+v+ +   Rv+G L++sRa+Gd ++k         +++++ P++ + +++ +++

Q: 377   IKNAGGKVTMDG--RVNGGLNLSRAIGDHFYKrnknlppeeQMISALPDIKVLTINDDHD  434

         ***********9..**********************************************

S: 204   fliLasDGlwdvvsneeavslvrdvle......kkeaeqeaakkLvklalargsk.....  252

         f+++a+DG+w+v+s++e+v+++++ ++        ++++++ ++L++++la  ++

Q: 435   FMVIACDGIWNVMSSQEVVDFIQSKITqkdengVLRPLSSIVEELLDQCLAPDTSgdgtg  494

         ************************999888877778899999999999999999987888

S: 253   .dnvsaiv  259

          dn++ i+

Q: 495   cDNMTCII  502

88877776

Domain Sequence
(FASTA)

MEGKEEPGSD SGTTAVVALI RGKQLIVANA GDSRCVVSEG GKAVDMSYDH KPEDEVELAR 60

IKNAGGKVTM DGRVNGGLNL SRAIGDHFYK RNKNLPPEEQ MISALPDIKV LTINDDHDFM 120

VIACDGIWNV MSSQEVVDFI QSKITQKDEN GVLRPLSSIV EELLDQCLAP DTSGDGTGCD 180

NMTCII 186

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0007050	; P:cell cycle arrest
GO:0035970	; P:peptidyl-threonine dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 2.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013