EKS-TEN-00189

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00189

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	500.5	1.6E-150	90	382	293

Status

Unreviewed

Ensembl Protein

ENSTNIP00000005419

UniProt Accession

H3CAZ7;

Protein Name

Protein Synonyms/Alias

Gene Name

STK38L

Gene Synonyms/Alias

STK38L;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000002853	ENSTNIP00000005419	ENSTNIT00000005565

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

462

Protein Sequence
(FASTA)

MAMTGGTAAA LPMSNHTRER VTVAKVTLEN FYSTLLTQHE EREMRQKKLE KAMDEEGLPD 60

EEKVMRRSQH ARKETEFLRL KRTRLGLDDF ESLKVIGRGA FGEVRLVQKK DTGHIYAMKI 120

LRKADMLEKE QCAHIRAERD ILVEADSAWV KMFYSFQDKR NLYLIMECLP GGDMMTLLMK 180

KDTLSEEATQ FYIAETVLAI DSIHQLGFIH RDIKPDNLLL DSRGHVKLSD FGLCTGLKKA 240

HRTEFYRNLT HNPPSDFSFQ NMNSKRKAET WKKNRRQLAY STVGTPDYIA PEVFMQTGYN 300

KLCDWWSLGV IMYEMLIGYP PFCSETPQET YRKVMNWKET LVFPPEVPIS ERAKDLILRY 360

CTDAENRIGA ANVEEIRSHQ FFELVDWEHI RERPAAISIE IKSIDDTSNF DDFPESDILQ 420

PASATEPDFK SKDWVFLNYT YKRFEGLTQR GTIPTYMKAG KA 462

Nucleotide Sequence
(FASTA)

ATGGCCATGA CGGGAGGGAC GGCAGCTGCC CTTCCCATGA GCAACCACAC CAGAGAGAGG 60

GTGACGGTGG CCAAAGTGAC GCTGGAGAAC TTCTACAGCA CCCTGCTCAC CCAGCACGAG 120

GAGCGGGAAA TGAGACAAAA GAAGCTGGAG AAAGCGATGG ATGAGGAGGG CTTACCGGAC 180

GAGGAGAAAG TAATGCGGCG CTCGCAGCAC GCCCGCAAGG AGACCGAGTT CCTGCGGCTG 240

AAGAGGACGC GACTCGGACT GGATGACTTC GAGTCCCTCA AAGTCATCGG ACGAGGTGCT 300

TTCGGAGAGG TGCGCCTGGT GCAGAAAAAA GACACGGGCC ACATCTACGC CATGAAAATC 360

CTGCGAAAAG CTGACATGCT GGAGAAAGAG CAGTGCGCTC ACATTCGCGC CGAGAGGGAC 420

ATCCTGGTGG AGGCGGACAG CGCCTGGGTC AAGATGTTCT ACAGCTTCCA GGATAAGAGA 480

AACCTTTACC TCATCATGGA GTGCCTGCCT GGAGGCGACA TGATGACGCT GCTGATGAAG 540

AAGGACACGC TGTCCGAGGA GGCCACCCAG TTCTACATCG CCGAGACGGT GTTGGCCATC 600

GACTCCATCC ACCAGCTGGG CTTCATCCAC CGGGACATCA AACCGGACAA CCTGCTGCTG 660

GACTCCAGGG GTCACGTGAA GCTGTCAGAT TTCGGCCTGT GCACGGGCCT CAAGAAAGCC 720

CATCGCACGG AGTTTTACAG GAACCTGACC CACAACCCGC CCAGCGATTT CTCGTTCCAG 780

AATATGAACT CCAAGAGGAA AGCGGAAACC TGGAAGAAGA ACCGGAGGCA GCTGGCCTAT 840

TCCACGGTGG GAACGCCCGA CTACATCGCT CCCGAAGTCT TCATGCAGAC CGGCTACAAC 900

AAGCTGTGCG ACTGGTGGTC CCTGGGGGTC ATCATGTACG AGATGCTCAT CGGCTACCCA 960

CCGTTTTGCT CCGAGACGCC ACAGGAGACC TACAGGAAGG TGATGAACTG GAAGGAGACC 1020

CTGGTCTTCC CGCCCGAAGT CCCCATCTCC GAGAGGGCCA AAGACCTGAT ATTAAGGTAC 1080

TGCACCGATG CCGAGAACAG GATCGGAGCT GCCAACGTGG AGGAGATCAG GAGTCATCAG 1140

TTCTTTGAGT TGGTGGACTG GGAGCACATC AGGGAACGCC CGGCGGCCAT CTCCATCGAA 1200

ATCAAGAGCA TAGACGACAC GTCCAACTTT GACGACTTCC CAGAGTCCGA CATCCTTCAG 1260

CCAGCCAGCG CAACAGAGCC AGACTTCAAG TCCAAGGACT GGGTCTTCCT GAACTACACC 1320

TACAAACGCT TCGAGGGTCT GACCCAGCGC GGCACCATCC CCACGTACAT GAAGGCGGGC 1380

AAGGCCTGA 1389

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt+++ya+kilrk+d+l+k+q ah++aerdil+eads+w

Q: 90    FESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQCAHIRAERDILVEADSAW  149

         899*********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtllikkeilkeelarfyiaelvlavesvhklGf  120

         v k++ysfqdk+nlyl+me lPGGd+mtll+kk++l+ee+++fyiae+vla++s+h+lGf

Q: 150   V-KMFYSFQDKRNLYLIMECLPGGDMMTLLMKKDTLSEEATQFYIAETVLAIDSIHQLGF  208

         5.9*********************************************************

S: 121   ihrdlkPdnllidakGhikltdfGlctGlkkthrseyykelekakeddleaseelkvler  180

         ihrd+kPdnll+d++Gh+kl+dfGlctGlkk+hr+e+y++l+++ ++d+++++  ++ +

Q: 209   IHRDIKPDNLLLDSRGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKA  268

         *************************************************65555555555

S: 181   rkkkknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypPflaetpq  240

            kknrr+lays+vGtpdyiapev++++gynklcdwWslGvi+yeml+GypPf++etpq

Q: 269   ETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQ  328

         555*********************************************************

S: 241   etykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpff  294

         ety+kv+nwketl fp+ev++se+akdli r+++dae+r+g+  v+ei++h+ff

Q: 329   ETYRKVMNWKETLVFPPEVPISERAKDLILRYCTDAENRIGAANVEEIRSHQFF  382

         *****************************************************9

Domain Sequence
(FASTA)

FESLKVIGRG AFGEVRLVQK KDTGHIYAMK ILRKADMLEK EQCAHIRAER DILVEADSAW 60

VKMFYSFQDK RNLYLIMECL PGGDMMTLLM KKDTLSEEAT QFYIAETVLA IDSIHQLGFI 120

HRDIKPDNLL LDSRGHVKLS DFGLCTGLKK AHRTEFYRNL THNPPSDFSF QNMNSKRKAE 180

TWKKNRRQLA YSTVGTPDYI APEVFMQTGY NKLCDWWSLG VIMYEMLIGY PPFCSETPQE 240

TYRKVMNWKE TLVFPPEVPI SERAKDLILR YCTDAENRIG AANVEEIRSH QFF 293

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013