EKS-TEN-00133

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00133

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MLCK	374.1	3.5E-112	2	241	240

Status

Unreviewed

Ensembl Protein

ENSTNIP00000005577

UniProt Accession

H3CBF5;

Protein Name

Protein Synonyms/Alias

Gene Name

MYLK

Gene Synonyms/Alias

MYLK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000003008	ENSTNIP00000005577	ENSTNIT00000005725

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

409

Protein Sequence
(FASTA)

FKLVEKATKK VWAGKFIKAY SAKEKDNVRQ EISIMNSLHH PKLVQCIDAF EGKSDIVMVL 60

EMISGGELFE RIIDEDFELT EREVIKYMLQ IIDGVNFIHK QGVVHLDLKP ENIMCVNKTG 120

SKIKLIDFGL ARRLENAGTL KVLFGTPEFV APEVINYEAI GYATDMWSIG VICYILLSGL 180

SPFMGDNDNE TLSNVTSATW DFEDEAFDEI SENAKDFITN LLKKDMKARL TCAQCFEHPW 240

LKQDTNTMKA KKLSKERMKK YILRRKWQKT GHAVRAIGRL SSMAMMAGVS AKKGSPTEED 300

NQFLECLEYE QKTECKPTFS NSHDVEVVEG SAARFDCKIE GYPDPEVVWY KDDQPIKETR 360

HFQIDYDEDG NCSLVISEVS GDDDAKYTVK AVNSLGEATC TADLLVEVM 409

Nucleotide Sequence
(FASTA)

TTTAAACTGG TGGAGAAGGC GACGAAGAAG GTCTGGGCAG GCAAGTTTAT TAAGGCCTAC 60

TCAGCAAAGG AGAAGGACAA CGTTCGGCAG GAGATCAGCA TCATGAACAG CCTTCATCAC 120

CCAAAACTTG TTCAGTGTAT TGACGCCTTC GAGGGCAAAT CCGACATCGT CATGGTCCTG 180

GAGATGATCT CCGGGGGGGA GCTCTTTGAG CGGATCATCG ATGAGGACTT TGAGTTAACA 240

GAAAGAGAAG TGATCAAATA CATGCTGCAG ATCATTGATG GCGTTAATTT CATTCACAAG 300

CAGGGCGTCG TTCACCTCGA TCTTAAGCCT GAGAACATTA TGTGTGTCAA CAAAACAGGC 360

AGCAAGATCA AACTCATCGA TTTTGGCCTT GCTAGACGAC TAGAAAATGC CGGAACTTTA 420

AAAGTTCTGT TTGGGACCCC GGAATTTGTT GCCCCAGAAG TGATCAACTA TGAAGCCATC 480

GGCTACGCCA CCGACATGTG GAGCATTGGA GTGATCTGCT ACATCCTGCT CAGTGGTCTG 540

TCTCCGTTCA TGGGGGACAA TGACAATGAA ACTTTGTCCA ACGTCACCTC GGCAACTTGG 600

GACTTTGAGG ATGAGGCCTT TGATGAAATC TCTGAAAATG CCAAAGATTT TATCACCAAC 660

CTACTTAAGA AAGACATGAA GGCTCGGCTA ACCTGTGCTC AGTGTTTTGA ACACCCTTGG 720

CTAAAACAGG ACACCAACAC CATGAAGGCC AAAAAACTCT CAAAGGAGAG GATGAAAAAG 780

TACATCCTGA GGAGGAAGTG GCAGAAAACC GGCCACGCTG TTCGAGCCAT CGGCAGGCTG 840

TCGTCCATGG CCATGATGGC CGGGGTCAGT GCCAAGAAGG GCTCGCCGAC TGAAGAAGAT 900

AACCAGTTTC TCGAGTGTTT GGAATATGAG CAGAAGACTG AGTGTAAGCC GACCTTTAGC 960

AACAGTCATG ACGTGGAGGT CGTAGAAGGT AGCGCCGCTC GTTTCGACTG TAAAATTGAA 1020

GGTTACCCAG ATCCAGAGGT GGTGTGGTAC AAAGACGATC AGCCAATCAA AGAGACACGG 1080

CATTTCCAAA TTGACTACGA TGAAGATGGA AACTGCAGTT TGGTCATTTC AGAGGTATCA 1140

GGTGACGACG ATGCCAAATA CACTGTGAAG GCCGTCAACA GTCTGGGCGA GGCAACCTGC 1200

ACAGCTGACC TGCTGGTGGA GGTGATG 1227

Domain Profile

S: 17    kavekstgkklaakivkvrkekdkeevkkEieilnqlrHekliqlydafeskeeivlvlE  76

         k vek+t+k++a+k++k+ ++k+k++v++Ei+i+n+l+H+kl+q++dafe k++iv+vlE

Q: 2     KLVEKATKKVWAGKFIKAYSAKEKDNVRQEISIMNSLHHPKLVQCIDAFEGKSDIVMVLE  61

         689*********************************************************

S: 77    lveggelferiveedyeltEeevvlfvrqvlealeylHkkgivHldlkpenillqskksk  136

         +++ggelferi++ed+eltE+ev++++ q++++++++Hk+g+vHldlkpeni++++k+++

Q: 62    MISGGELFERIIDEDFELTEREVIKYMLQIIDGVNFIHKQGVVHLDLKPENIMCVNKTGS  121

         ************************************************************

S: 137   qiKlidFGlarklkkkeklkvlfgtpefvaPEvvnkepvslatDmWsvGvityvLlsGls  196

         +iKlidFGlar+l+++ +lkvlfgtpefvaPEv+n+e +++atDmWs+Gvi+y+LlsGls

Q: 122   KIKLIDFGLARRLENAGTLKVLFGTPEFVAPEVINYEAIGYATDMWSIGVICYILLSGLS  181

         ************************************************************

S: 197   PFlgdndeetlenvssakydfdeeafkevseeakdFiskllvkekkkRmsaeeaLkhkwl  256

         PF+gdnd+etl+nv+sa++df++eaf+e+se+akdFi++ll+k++k+R++++++++h+wl

Q: 182   PFMGDNDNETLSNVTSATWDFEDEAFDEISENAKDFITNLLKKDMKARLTCAQCFEHPWL  241

         ***********************************************************8

Domain Sequence
(FASTA)

KLVEKATKKV WAGKFIKAYS AKEKDNVRQE ISIMNSLHHP KLVQCIDAFE GKSDIVMVLE 60

MISGGELFER IIDEDFELTE REVIKYMLQI IDGVNFIHKQ GVVHLDLKPE NIMCVNKTGS 120

KIKLIDFGLA RRLENAGTLK VLFGTPEFVA PEVINYEAIG YATDMWSIGV ICYILLSGLS 180

PFMGDNDNET LSNVTSATWD FEDEAFDEIS ENAKDFITNL LKKDMKARLT CAQCFEHPWL 240

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR007110	; Ig-like.
IPR013783	; Ig-like_fold.
IPR013098	; Ig_I-set.
IPR003598	; Ig_sub2.
IPR011009	; Kinase-like_dom.
IPR020675	; Myosin_light_ch_kinase-rel.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF07679	; I-set; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00408	; IGc2; 1.
SM00220	; S_TKc; 1.

Prosites

PS50835	; IG_LIKE; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013