EKS-TEN-00080

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00080

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	410.1	4.8E-123	4	285	282

Status

Unreviewed

Ensembl Protein

ENSTNIP00000005755

UniProt Accession

H3CBY3;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK1

Gene Synonyms/Alias

CDK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000003176	ENSTNIP00000005755	ENSTNIT00000005903

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

300

Protein Sequence
(FASTA)

MDDYLKIEKI GEGTYGVVYK GRHKATGQVV AMKKIRLESE EEGVPSTAIR EVSLLQELKH 60

PNVVRLLEVL MHDSRLYLIF EFLSMDLKKY LDSIPSGQYM EPMLVKSYLY QILEGILFCH 120

CRRILHRDLK PQNLLIDNKG VIKLADFGLA RAFGVPVRVY THEVVTLWYR APEVLLGSPR 180

YSTPIDVWST GTIFAELATK KPLFHGDSEI DQLFRIFRTL GTPNNDVWPD VESLPDYKST 240

FPKWKSGNLS VKNLDKDALD LLAKMLTYNP PKRISAREAM KHPYFDDLDK STLPSATNQI 300

Nucleotide Sequence
(FASTA)

ATGGATGACT ATCTGAAGAT CGAGAAAATT GGTGAAGGTA CCTATGGGGT GGTGTACAAG 60

GGCAGACACA AGGCCACGGG GCAGGTGGTG GCCATGAAGA AGATCCGCCT GGAGAGCGAG 120

GAAGAGGGCG TTCCCAGCAC GGCCATCAGG GAGGTGTCCC TGCTGCAGGA GCTGAAGCAC 180

CCCAACGTTG TCCGGCTCCT GGAGGTGCTG ATGCACGACT CCCGCCTCTA CCTCATCTTT 240

GAGTTTCTGT CCATGGACCT GAAGAAGTAC CTGGACTCCA TCCCCTCAGG CCAGTACATG 300

GAGCCGATGC TGGTGAAGAG CTACCTCTAT CAGATCCTGG AGGGCATCCT CTTCTGCCAC 360

TGTCGCCGGA TTCTCCACCG GGACCTGAAG CCCCAGAACC TGCTGATCGA CAACAAGGGC 420

GTCATCAAAC TGGCTGACTT CGGCCTGGCT CGGGCCTTCG GCGTCCCGGT CAGGGTCTAC 480

ACCCACGAGG TGGTGACGCT GTGGTACCGC GCTCCCGAGG TTCTCCTGGG GTCCCCCCGC 540

TACTCCACCC CCATTGACGT GTGGAGCACC GGGACCATCT TTGCTGAGCT GGCAACCAAA 600

AAGCCTCTGT TTCATGGAGA CTCGGAGATC GATCAGCTCT TCAGGATCTT CAGGACTCTG 660

GGAACGCCAA ACAATGACGT GTGGCCTGAT GTGGAGAGCT TGCCTGACTA CAAAAGCACC 720

TTTCCCAAGT GGAAAAGTGG GAACTTGTCT GTGAAGAACC TGGACAAGGA CGCCCTGGAC 780

CTCCTGGCGA AAATGTTGAC CTACAACCCC CCGAAAAGGA TCTCTGCCCG CGAAGCCATG 840

AAGCATCCTT ATTTTGACGA CCTGGATAAA TCCACCCTCC CCTCTGCCAC CAACCAGATC 900

TAA 903

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y k+ekigeGtyg+vyk+++k tg+vvA+Kkirle+e+egvp+ta+rE+sll+elkh+n+

Q: 4     YLKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLESEEEGVPSTAIREVSLLQELKHPNV  63

         779*********************************************************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkk.klsleevkslllqlleglaylHsn  119

         v+Llev++ ++++lyL+fefl++dLkk+l++ ++  ++++  vks+l+q+leg+ ++H +

Q: 64    VRLLEVLM-HDSRLYLIFEFLSMDLKKYLDSIPSGqYMEPMLVKSYLYQILEGILFCHCR  122

         ********.99********************9876589999*******************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYs  179

         +ilHRDlKpqNlLi+++g++klaDfGlaraf++p++ yt+evvTlwYraPe+Llg+ +Ys

Q: 123   RILHRDLKPQNLLIDNKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGSPRYS  182

         ************************************************************

S: 180   tavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeykksfp  239

         t +D+Ws g i+ael+t+kplf+g+seidql+rif++lgtp+++vwp+v++lp+yk++fp

Q: 183   TPIDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNDVWPDVESLPDYKSTFP  242

         ************************************************************

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k+k+ +l+   k+l+++aldll k+l+++p kRisa+ea++h+yf

Q: 243   KWKSGNLSV--KNLDKDALDLLAKMLTYNPPKRISAREAMKHPYF  285

         **9999975..569******************************9

Domain Sequence
(FASTA)

YLKIEKIGEG TYGVVYKGRH KATGQVVAMK KIRLESEEEG VPSTAIREVS LLQELKHPNV 60

VRLLEVLMHD SRLYLIFEFL SMDLKKYLDS IPSGQYMEPM LVKSYLYQIL EGILFCHCRR 120

ILHRDLKPQN LLIDNKGVIK LADFGLARAF GVPVRVYTHE VVTLWYRAPE VLLGSPRYST 180

PIDVWSTGTI FAELATKKPL FHGDSEIDQL FRIFRTLGTP NNDVWPDVES LPDYKSTFPK 240

WKSGNLSVKN LDKDALDLLA KMLTYNPPKR ISAREAMKHP YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0009794	; P:regulation of mitotic cell cycle, embryonic

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013