EKS-TEN-00120

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00120

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	335.2	5.1E-100	1938	2268	331

Status

Unreviewed

Ensembl Protein

ENSTNIP00000006118

UniProt Accession

H3CCZ5;

Protein Name

Protein Synonyms/Alias

Gene Name

ATM (1 of 2)

Gene Synonyms/Alias

ATM (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000003530	ENSTNIP00000006118	ENSTNIT00000006266

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

2313

Protein Sequence
(FASTA)

QVLLQELSGF VYSAKVKMAE NQRMSTLRTV IRLCTQSSGR NRKDGVSLVS CRLWATLLPS 60

SLLSELAEVS KVLSSGPSER APAVDDGDRA DEDWDASRTP RSEEVDLFDE GTSPSGSSGS 120

SGQKTEAGDG AGGPGARSPL SEEHLTQGDL ALLAVVDFLC ECGSVQPVHR LHFKPQEVRR 180

KLLLLLEQVD FSRALHLHYL VLLRKLPAGD SLAPEEFTSL LRPLADLCSD YRQDQDVCAA 240

VLLALLPSVR SLGGCPHPPE DLTHVRGMLL HMVSGFCYLS QTGKCVAPVR VALVRCLVAL 300

LEADPRCRWA VLSLKGQDGR EKDVSAVLSS HLADAHHQVR MLVATSVERF FLEVGPDRKM 360

LPLKQQQEAF EHVYLRAQEG MLLPKNCSPD DQRDESSNRK AALLRSLCVV LCCSPVCEKQ 420

ALFALFQSYK ENSIEEQLIK KILGSVCGVL GYSSVRTFVG SHLYYLVAEW LAQRQSDDRY 480

TLGSFPYSVL DQETVAGFYR RSSYQVLVPH LVLLDDFEQV KSIGRCLGKD WKELLADCFP 540

KIMVNILPYF ALGGQEALVA QQREKAHRVY DLLTDSSYLG KQEIDSLIHS NLADIVVELL 600

MTLYEGSGPE GDLRRFVGEL DPAPNPPYFS SSVIKATLDY LSRCHSTSRR SLVAVLSKTP 660

ISIQRILLAV CERGAGTTNG YERHRILLVY HLFVSLLLAE VEDGLGGAWA FVLRDVVYTL 720

VHHINSSPLR PVEVSDRSVA LCCDLLTSVC RAALRFCDGA LDCHLQVIVG TLMAQVTSRP 780

PPISQQMLGL LQFLIIENQQ KLKEVISKLE PFPNLPEFAE LRSVQKKLQP GTSTLSQEVM 840

RFLSVTSCDS VLLTRLEGLK QLSRQLRDNR AQIRELLRQC HAEHGDSLPV KLVLSLLQLC 900

KLAVHQPGGA DILEAVGSCL GELGPVDLST IALLHGRDPL YKRSADLFDS PELQQLYVAL 960

SCMNDALTQP SIEVRSAAAL CVKNLLAAQS GVDFWEKYKD SQDPLLIYLN PLRKAKKKVE 1020

ALSAEQSPEA RDKLEDRSLW VVQAGSHRPW LKTLCTALLD SGGVRSEALL LSRPLCLVWA 1080

DCCQRLLPLM HSVLQHDPDG SWRCSLSSCF QEFFRFCCRR PQASSRSTTP LSCDSESDAS 1140

SQGVHDKNSL RTMLAVLDYL RHQKRASSDG SDGTVCDSNF WLELNYLEVA KAAQSCSAHF 1200

TALLYAEIYV DKLKADLEDA HRSTSRATRR LTFEDTSQTF SISSLNKKSV EDAQISLQEL 1260

LFEVYRSIGE PDSLYGCGGE TVTSPLTRIR TYEHEALWGK ALTSYDLHTS LPEVTRHVGI 1320

VEGLQNFGLS GILATYMRGL ESEGVELGWE LRELRFQAAW RNSQWDCELP ERDELQPGFH 1380

QSVFCSLQAL RDREFSVFEQ MVKQARTALV EELCRGSLEA VSSLYPALRD LQSIRQLEDI 1440

HPLFSRPFSG VGLEDVCRQW RQQSQLLGDS DFALVEPILA ARSVGLHSLM TRMGDPDSRQ 1500

HVGSMLTEHL LDMCQLARKA GNTQLAERAV FQMKQHASAG SWVLTPVSSW QLEEAQVFWA 1560

KGDQELALGL LRRIVSNLEE TVDLNPALVP VYTESLRLCG NWLAETCLES PGVILENYLE 1620

RVYPDVLALL PRAAFKDARL LRQRTEAFLS LARFSDMQYQ IIGKYMSSSE FENKQALLQK 1680

AKEEVGLLRE HNVVGRYTTK VQKELELDEK ALSNLQADRR RFLCKAVENY VQCLEEGEEH 1740

DTWVFRLASL WLENGHVAAV NATMENGVKK IPSHKFLPLM YQLAARMGTK TVSEDRGFHG 1800

VLFELISRAC LEHPHHTLFI ILALVNANKD KAFCEVPVSK GVPWEPSPLD LERSDKAQMI 1860

VNVVRKKRSQ LVRGMERLSD AYITLAYMDA SRHKTEKREI PIPADQPIVK IRDLDEVVIP 1920

TLELKVDPSG RYDNLVTIRS FMPRYKLVGG VNLPKIIHCV GSDGESRRQL VKGKDDLRQD 1980

AVMQQVFGMC SMLLQRNSDT RKRKLNIRRY KVVPFSQKSG VLEWCSETVP ISLFLVDPKQ 2040

GAHRRFRPQD WTSMECRVKM MVRLRNAVGF DEKLQAYAEV CRNFRPVFRF FCMERFQDPA 2100

VWMEKRLAYT RSVATSSIVG YIVGLGDRHI NNILIDEQSA ELIHIDLGVA FEQGKILPTP 2160

ETVPFRLSRD IVDGMGITGV EGVFRRCCEK TLEVMRSSLE ALLTIVEVLL YDPLFDWTMN 2220

PLKALYLQRD EQQELNATLG STMGRDHLDS QRKLRDSQSF NKVAERLLRL QEKLKGVEEG 2280

AVLSVGGQVN LLIQQALDPR NLSRLFPGWQ AWV 2313

Nucleotide Sequence
(FASTA)

CAGGTGCTGC TGCAGGAGCT GAGCGGTTTC GTTTATTCTG CCAAAGTGAA GATGGCAGAG 60

AACCAACGCA TGAGCACGCT GAGGACCGTC ATCAGGCTGT GCACGCAGTC GTCCGGCAGA 120

AACAGGAAGG ACGGAGTTTC CCTGGTCTCC TGCCGGTTGT GGGCGACGCT GCTGCCGTCC 180

AGCCTCCTCA GCGAGCTGGC CGAAGTCAGC AAAGTCCTCT CAAGCGGCCC TTCGGAGCGA 240

GCTCCTGCGG TGGACGACGG GGATCGCGCG GACGAGGACT GGGACGCCAG CAGAACCCCC 300

CGGAGCGAGG AGGTGGACCT CTTTGACGAG GGGACCAGCC CCAGTGGATC CAGCGGGTCC 360

AGTGGGCAGA AGACGGAGGC CGGCGACGGC GCGGGTGGTC CAGGGGCCCG AAGTCCACTT 420

TCAGAGGAGC ACCTGACCCA AGGGGACCTG GCTCTGCTGG CCGTGGTGGA CTTCCTGTGT 480

GAGTGCGGTT CCGTCCAGCC CGTCCACCGT CTGCACTTCA AGCCGCAGGA GGTGCGGCGC 540

AAGCTGCTGC TGCTGCTGGA GCAGGTGGAC TTCAGCAGGG CTCTGCATCT CCACTACCTG 600

GTCCTGCTGA GGAAGCTGCC TGCTGGAGAC TCTCTGGCCC CAGAAGAGTT CACCTCCCTG 660

CTCCGCCCTC TTGCCGACCT GTGTTCGGAC TACCGCCAGG ACCAAGACGT CTGCGCCGCT 720

GTCCTGCTGG CCCTGCTGCC CTCCGTCAGG AGTCTGGGCG GGTGCCCCCA CCCGCCCGAG 780

GACCTGACCC ACGTTCGGGG AATGCTGCTC CATATGGTGT CTGGATTCTG CTACCTGAGC 840

CAGACGGGGA AATGCGTGGC CCCCGTCCGC GTGGCCCTGG TGCGATGTCT GGTGGCTCTG 900

CTGGAGGCCG ACCCGCGCTG TCGCTGGGCC GTTTTGAGCC TGAAGGGCCA GGACGGCAGA 960

GAAAAGGACG TGTCGGCCGT GCTCTCGTCC CACCTGGCGG ATGCCCACCA TCAGGTTCGC 1020

ATGCTGGTGG CCACGTCGGT GGAGAGGTTC TTCCTGGAGG TTGGGCCCGA CCGGAAGATG 1080

CTGCCCCTGA AGCAGCAGCA GGAGGCCTTC GAGCACGTTT ACCTGAGGGC TCAGGAGGGG 1140

ATGCTCCTCC CGAAGAACTG CTCCCCGGAC GACCAGCGGG ACGAGTCCTC CAACCGCAAG 1200

GCGGCCCTGT TGAGGAGTCT GTGCGTGGTG CTCTGCTGCA GCCCCGTCTG TGAGAAGCAG 1260

GCGCTCTTCG CCCTCTTCCA GTCCTACAAG GAGAACAGCA TAGAGGAGCA GCTCATCAAG 1320

AAGATACTGG GCAGTGTGTG TGGAGTGCTG GGCTACAGCA GTGTGAGGAC CTTCGTGGGC 1380

TCCCATCTCT ACTACCTGGT GGCGGAGTGG TTGGCGCAGA GGCAGTCGGA CGACCGCTAC 1440

ACCCTGGGCT CCTTTCCCTA CAGCGTCCTG GACCAGGAGA CGGTTGCAGG CTTCTACAGA 1500

AGGTCCTCCT ACCAGGTCCT GGTCCCTCAC CTGGTCCTCC TGGATGACTT TGAGCAGGTG 1560

AAGTCCATCG GCAGGTGTCT GGGGAAGGAC TGGAAGGAGC TACTGGCCGA CTGTTTCCCT 1620

AAAATCATGG TGAACATCCT GCCCTACTTC GCCCTGGGCG GCCAGGAGGC GCTGGTGGCG 1680

CAGCAGCGGG AGAAGGCCCA CAGGGTGTAC GACCTGCTGA CGGACAGCAG CTACCTGGGC 1740

AAACAGGAGA TCGACTCCCT GATCCACAGC AACCTGGCAG ACATCGTGGT GGAGCTGCTG 1800

ATGACGCTGT ACGAAGGGAG TGGACCCGAA GGGGACCTGC GGCGCTTTGT GGGGGAATTG 1860

GACCCCGCGC CCAACCCGCC CTATTTCAGC TCCTCCGTGA TCAAAGCCAC CCTGGACTAC 1920

CTGAGCCGAT GCCACAGCAC CAGCCGCAGG TCCCTGGTGG CCGTCCTGTC CAAAACTCCG 1980

ATCTCCATCC AGAGGATCCT GCTGGCCGTG TGCGAGAGGG GGGCGGGAAC CACCAACGGC 2040

TACGAGCGCC ACCGCATCCT CCTCGTGTAC CACCTGTTTG TGAGCCTGCT GCTGGCGGAG 2100

GTGGAGGACG GTCTGGGAGG AGCCTGGGCC TTCGTCCTCA GGGACGTCGT GTACACGCTC 2160

GTTCACCACA TCAACAGCAG CCCGCTTCGC CCCGTCGAGG TTTCCGACAG AAGCGTCGCT 2220

CTCTGCTGCG ACCTCTTGAC ATCCGTGTGC CGCGCGGCTC TGCGGTTCTG CGACGGCGCT 2280

CTAGACTGCC ATCTACAGGT CATCGTGGGG ACTCTGATGG CCCAGGTGAC CAGCCGGCCC 2340

CCTCCCATCT CGCAGCAGAT GCTCGGACTG CTGCAGTTCC TCATCATAGA GAATCAGCAG 2400

AAACTGAAAG AGGTCATCAG CAAGTTGGAG CCGTTTCCGA ACCTCCCTGA GTTCGCGGAG 2460

CTGCGATCTG TGCAGAAGAA GCTCCAGCCG GGGACCTCCA CACTGAGCCA GGAGGTGATG 2520

CGCTTCCTGT CGGTCACCTC CTGCGACTCC GTGCTCCTGA CCAGACTGGA GGGCCTGAAG 2580

CAGCTGAGCC GACAGCTCCG TGACAACAGG GCGCAGATCA GGGAGCTCCT CCGCCAATGC 2640

CACGCGGAGC ATGGCGACAG CCTGCCGGTA AAGCTGGTGC TCAGCCTGCT GCAGCTGTGT 2700

AAACTGGCGG TCCACCAGCC CGGAGGAGCC GACATCCTCG AGGCCGTGGG CAGCTGTCTG 2760

GGAGAACTGG GACCTGTGGA CCTGTCCACC ATCGCCCTGC TGCACGGCAG AGACCCCCTC 2820

TATAAGAGGT CGGCCGATCT CTTCGACTCC CCCGAGCTGC AGCAGCTCTA CGTCGCCCTC 2880

AGCTGCATGA ACGACGCGCT CACTCAGCCC AGCATCGAAG TGAGATCGGC TGCTGCTCTG 2940

TGCGTGAAGA ACCTCCTGGC TGCTCAGTCT GGTGTGGATT TCTGGGAGAA GTACAAAGAC 3000

AGCCAGGACC CCCTGCTGAT CTACCTGAAT CCCCTCAGGA AGGCCAAGAA AAAGGTGGAA 3060

GCGCTCAGTG CTGAGCAGAG CCCGGAGGCC CGGGACAAGC TGGAGGACCG GTCGTTGTGG 3120

GTGGTCCAGG CAGGCAGCCA CAGGCCCTGG CTGAAGACGC TGTGCACCGC CCTGCTGGAC 3180

AGCGGAGGGG TCAGGAGCGA AGCGCTGCTG CTGTCCCGGC CCTTGTGTCT GGTGTGGGCA 3240

GACTGCTGTC AGCGGCTGCT GCCCCTCATG CACTCCGTCC TCCAGCACGA CCCTGACGGT 3300

TCCTGGAGGT GCTCGCTCTC CTCCTGCTTC CAGGAGTTCT TCCGCTTCTG CTGCAGGAGG 3360

CCTCAGGCCT CCAGCCGCTC CACCACGCCG CTCAGCTGCG ACTCGGAGTC GGATGCTTCC 3420

AGTCAGGGTG TGCACGACAA GAACTCCCTG CGCACCATGT TGGCTGTTCT GGACTACCTG 3480

AGACACCAGA AACGAGCGTC CTCTGACGGC TCTGACGGGA CCGTGTGTGA CTCAAACTTC 3540

TGGCTGGAGC TGAACTACCT GGAGGTGGCC AAAGCTGCTC AGTCCTGCTC GGCGCATTTC 3600

ACCGCCCTGC TGTACGCGGA GATCTACGTG GACAAGCTCA AGGCTGACCT GGAGGACGCC 3660

CACAGGTCCA CGTCCAGGGC AACGCGCAGA CTCACCTTTG AAGACACCAG CCAGACCTTC 3720

AGCATCTCCA GCCTCAACAA GAAGAGCGTG GAAGACGCCC AAATCAGCCT GCAGGAGCTG 3780

CTGTTCGAGG TCTACCGGAG CATCGGAGAA CCCGACAGCC TGTACGGCTG CGGCGGCGAG 3840

ACCGTGACCA GCCCCCTGAC CAGGATCCGG ACCTATGAAC ACGAGGCCCT GTGGGGGAAG 3900

GCCCTGACCT CCTACGACCT CCACACCTCT CTGCCCGAAG TCACCCGACA CGTTGGGATC 3960

GTAGAGGGCC TGCAGAACTT CGGCCTGAGC GGCATCCTGG CCACCTACAT GAGGGGCCTG 4020

GAGAGCGAAG GGGTGGAGCT GGGATGGGAG CTGAGGGAGC TCCGCTTCCA GGCTGCCTGG 4080

AGGAACTCCC AGTGGGACTG CGAGCTGCCA GAGAGGGACG AGCTCCAGCC CGGCTTCCAC 4140

CAATCGGTCT TCTGTTCCCT GCAAGCGCTG AGGGACCGGG AGTTCAGCGT GTTTGAGCAG 4200

ATGGTGAAGC AGGCTCGGAC TGCGCTGGTG GAGGAGCTGT GCAGGGGAAG TCTGGAGGCT 4260

GTGTCCTCCT TGTACCCGGC TCTCAGGGAC CTCCAGAGCA TCCGGCAGCT GGAGGACATC 4320

CATCCGCTCT TCTCCAGGCC CTTCTCGGGC GTGGGTCTGG AAGACGTCTG CCGCCAGTGG 4380

CGCCAGCAGT CGCAGCTGCT CGGTGACAGC GACTTTGCCC TGGTGGAGCC CATCCTGGCG 4440

GCGCGCTCGG TGGGCCTGCA CTCCCTGATG ACCAGGATGG GAGACCCCGA CAGCAGGCAG 4500

CACGTCGGCT CCATGCTGAC CGAGCATCTC CTGGACATGT GTCAGCTGGC TCGCAAGGCT 4560

GGGAACACAC AGCTGGCGGA GCGTGCAGTC TTCCAGATGA AACAGCACGC TTCGGCAGGG 4620

TCGTGGGTGT TGACCCCGGT GTCGTCATGG CAACTAGAGG AAGCCCAAGT GTTCTGGGCA 4680

AAGGGCGACC AGGAGCTGGC TCTGGGTCTG CTGAGGCGGA TCGTAAGCAA TTTGGAGGAA 4740

ACGGTGGACC TAAACCCCGC CCTGGTGCCA GTCTACACCG AGAGCCTCCG GCTGTGTGGT 4800

AACTGGCTGG CAGAGACGTG CCTGGAAAGT CCTGGAGTGA TCCTGGAAAA CTACCTGGAG 4860

AGGGTATACC CAGATGTTCT TGCTCTGCTG CCTCGTGCAG CGTTTAAGGA TGCCCGGCTG 4920

CTGCGCCAAC GGACAGAGGC CTTCCTGTCC CTGGCGCGCT TCTCCGACAT GCAGTACCAG 4980

ATTATCGGCA AGTACATGAG CTCCTCGGAG TTTGAGAACA AGCAGGCGCT GCTGCAGAAG 5040

GCCAAGGAGG AAGTGGGCTT GTTGCGGGAG CACAACGTGG TCGGCAGGTA CACCACGAAG 5100

GTGCAGAAGG AGCTGGAGCT GGACGAGAAG GCCTTGTCCA ACCTGCAGGC GGACAGGCGG 5160

CGCTTCCTCT GCAAGGCGGT GGAGAACTAC GTCCAGTGCC TGGAGGAGGG AGAGGAGCAC 5220

GACACCTGGG TGTTCCGCCT GGCCTCGCTC TGGCTGGAGA ACGGCCACGT GGCCGCCGTA 5280

AACGCCACCA TGGAGAACGG GGTGAAGAAG ATCCCCTCCC ACAAGTTTCT GCCTCTGATG 5340

TACCAGCTGG CCGCTCGTAT GGGCACGAAG ACGGTGTCCG AGGACAGGGG CTTCCACGGC 5400

GTCCTCTTCG AGCTGATCAG TAGAGCGTGT TTGGAGCACC CTCACCACAC GCTCTTCATC 5460

ATCCTAGCCC TGGTCAACGC CAACAAGGAC AAGGCCTTCT GCGAGGTGCC CGTGTCCAAG 5520

GGCGTCCCCT GGGAGCCCTC GCCCCTCGAC CTGGAGCGCT CCGACAAAGC CCAGATGATC 5580

GTCAACGTGG TCAGGAAGAA GAGAAGCCAG CTGGTGCGAG GGATGGAGCG CCTGAGCGAT 5640

GCCTACATCA CCCTGGCCTA CATGGACGCC AGCAGGCACA AAACCGAGAA GAGGGAGATT 5700

CCCATCCCTG CCGATCAGCC CATCGTGAAG ATCCGGGATC TGGACGAGGT GGTCATCCCC 5760

ACCCTGGAGC TGAAGGTGGA TCCATCCGGT CGCTACGACA ACCTGGTGAC GATCAGGTCC 5820

TTCATGCCTC GATATAAACT GGTGGGCGGA GTCAACCTGC CGAAGATCAT CCACTGCGTG 5880

GGCTCGGATG GGGAAAGTAG GAGGCAGCTG GTGAAGGGCA AGGACGACCT GCGGCAGGAT 5940

GCGGTGATGC AGCAGGTCTT CGGCATGTGC TCCATGCTGC TGCAGCGCAA CAGCGACACC 6000

CGCAAGAGGA AGCTCAACAT CAGGCGCTAC AAGGTGGTGC CCTTCTCCCA GAAGAGCGGT 6060

GTTCTGGAGT GGTGCTCCGA GACGGTGCCG ATCAGCCTCT TCCTGGTGGA CCCGAAGCAG 6120

GGAGCCCACC GGCGTTTCCG ACCGCAGGAC TGGACCAGCA TGGAGTGCCG CGTGAAGATG 6180

ATGGTGCGGC TGCGGAATGC CGTTGGCTTT GACGAGAAGC TCCAGGCCTA CGCCGAGGTG 6240

TGCCGCAACT TCCGGCCCGT CTTCCGGTTT TTCTGCATGG AGCGCTTTCA GGACCCGGCG 6300

GTGTGGATGG AGAAGCGGCT GGCCTACACC CGCAGCGTGG CCACCTCCTC CATAGTGGGC 6360

TACATCGTGG GCCTGGGGGA CCGCCACATC AACAACATCC TGATCGACGA GCAGAGCGCC 6420

GAGCTGATCC ACATCGACCT GGGCGTGGCC TTTGAGCAGG GGAAGATTCT CCCCACCCCC 6480

GAGACCGTCC CCTTCAGGCT GTCCAGGGAC ATCGTGGACG GCATGGGCAT CACCGGCGTG 6540

GAGGGCGTCT TCCGGAGGTG CTGTGAGAAG ACCCTGGAGG TGATGCGGAG CTCCCTGGAA 6600

GCTCTGCTGA CCATTGTGGA GGTGCTGCTC TACGACCCCC TGTTTGACTG GACCATGAAC 6660

CCCCTGAAGG CCTTGTACCT GCAGCGGGAC GAGCAGCAGG AGCTCAACGC CACCCTGGGC 6720

TCCACCATGG GCAGAGACCA CCTGGACAGC CAGCGCAAAC TCAGGGACAG TCAGAGCTTC 6780

AACAAGGTGG CGGAGCGCCT GCTGCGGCTG CAGGAGAAGC TGAAGGGGGT GGAGGAGGGC 6840

GCGGTGCTCA GCGTCGGGGG GCAGGTCAAC CTCCTGATCC AGCAGGCCCT GGACCCCAGG 6900

AACCTGAGCA GGCTGTTCCC AGGCTGGCAG GCCTGGGTGT AG 6942

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         i +f++r +++   + pk +   Gsdg ++++Lvkgk+Dlrqd++++q+f+++  lL+++

Q: 1938  IRSFMPRYKLVGGVNLPKIIHCVGSDGESRRQLVKGKDDLRQDAVMQQVFGMCSMLLQRN  1997

         6799********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdl  120

         + t++rkL+ir+ykVvp s++sg++ew+ +tv++  +l   v+ k++++    + r++d+

Q: 1998  SDTRKRKLNIRRYKVVPFSQKSGVLEWCSETVPISLFL---VDPKQGAHR---RFRPQDW  2051

         ***********************************999...799999997...9******

S: 121   stvqarkpklkhlkls......levfkevlenlvpkdllkklllekfpspeewfelrkay  174

           + +r +++  l         l+ + ev+ n+ p  +++ +++e f +p++w e+r ay

Q: 2052  TSMECRVKMMVRLRNAvgfdekLQAYAEVCRNFRP--VFRFFCMERFQDPAVWMEKRLAY  2109

         ******9999999888999999*************..9**********************

S: 175   trslAvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLT  234

         trs+A++s+vgyi+gLgdrh +n+lid++++e++hid+gvafe++k+ l++pe+vPFRL

Q: 2110  TRSVATSSIVGYIVGLGDRHINNILIDEQSAELIHIDLGVAFEQGKI-LPTPETVPFRLS  2168

         ***********************************************.************

S: 235   rnivnalgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk........k  286

         r+iv+++g+tgveGvfr++ce++l+v+r+s e llti+ev+lydpl+dw++        +

Q: 2169  RDIVDGMGITGVEGVFRRCCEKTLEVMRSSLEALLTIVEVLLYDPLFDWTMnplkalylQ  2228

         *****************************************************9998665

S: 287   kktsketeeelaekakaealkikkllskvekaenavatrdl  327

         + +++e + +l ++   ++l+++++l++ ++++n+va+r l

Q: 2229  RDEQQELNATLGSTMGRDHLDSQRKLRD-SQSFNKVAERLL  2268

         5566666667778888889999999966.678888888755

Domain Sequence
(FASTA)

IRSFMPRYKL VGGVNLPKII HCVGSDGESR RQLVKGKDDL RQDAVMQQVF GMCSMLLQRN 60

SDTRKRKLNI RRYKVVPFSQ KSGVLEWCSE TVPISLFLVD PKQGAHRRFR PQDWTSMECR 120

VKMMVRLRNA VGFDEKLQAY AEVCRNFRPV FRFFCMERFQ DPAVWMEKRL AYTRSVATSS 180

IVGYIVGLGD RHINNILIDE QSAELIHIDL GVAFEQGKIL PTPETVPFRL SRDIVDGMGI 240

TGVEGVFRRC CEKTLEVMRS SLEALLTIVE VLLYDPLFDW TMNPLKALYL QRDEQQELNA 300

TLGSTMGRDH LDSQRKLRDS QSFNKVAERL L 331

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0000077	; P:DNA damage checkpoint
GO:0006281	; P:DNA repair
GO:0016572	; P:histone phosphorylation
GO:0090399	; P:replicative senescence
GO:0010212	; P:response to ionizing radiation
GO:0000723	; P:telomere maintenance

KEGG

InterPros

IPR015519	; ATM/Tel1.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013