EKS-TEN-00559

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00559

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/DMPK	357.8	4.0E-107	98	362	265

Status

Unreviewed

Ensembl Protein

ENSTNIP00000007046

UniProt Accession

H3CFL9;

Protein Name

Protein Synonyms/Alias

Gene Name

CIT (2 of 3)

Gene Synonyms/Alias

CIT (2 of 3);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000004410	ENSTNIP00000007046	ENSTNIT00000007203

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

455

Protein Sequence
(FASTA)

MLKFKYVSQG NQPSLSPLDP ITIRSSRLNQ VFQGRVSLCG QQGGCTLGRE GLLEALLMLY 60

RECSSPALMK IHNVANFVNK FSEAVAELQA LQPCVKDFDV RAVVGRGHFS EVQLVREKAT 120

GDLCALKVMK KAVLGAKEKV VFYEEERRVL ALNSSPWIPQ LLYAFQDKEH VYLAMEYLPG 180

GDLMSLLNRY EDQFDESMAQ FYLAELVEAI NSVHQLGYVH RDIKPENVLI DRTGHIKLAD 240

FGSAARLTAN KTVAVPTLPV GTQDFLSPEI LTALNGGPNC TYGIECDWWS LGVIAYEMVY 300

ARSPFSEGTS AKTINNILNY QRFLKFPEEP RASKQFVDLL QKLLCGAKER LGFQGLRCHS 360

FFSSVDWNNL RQVRHRTSFV PQLHTEDDTS NFEEPEQAAP RPGSAAHQGA LPVGFQGQDL 420

PFLGWFFSRP LATLAKAEST STGLNSPAKA NSMEK 455

Nucleotide Sequence
(FASTA)

ATGTTGAAGT TTAAATACGT TAGCCAGGGA AACCAACCGT CACTTTCTCC GCTGGACCCA 60

ATCACCATCC GCAGCTCGCG GCTCAATCAA GTATTTCAGG GCCGGGTCAG TCTCTGCGGG 120

CAGCAGGGAG GATGCACCCT TGGTCGGGAA GGGCTTCTGG AGGCTCTGCT GATGCTGTAC 180

CGAGAGTGCT CCTCCCCAGC ACTCATGAAA ATCCACAACG TGGCAAACTT TGTCAATAAG 240

TTTTCTGAGG CGGTTGCAGA GCTGCAGGCG TTGCAGCCGT GCGTTAAAGA CTTCGACGTG 300

CGCGCAGTTG TGGGTCGGGG TCATTTTTCT GAAGTCCAAC TTGTCCGGGA GAAAGCCACT 360

GGTGACCTTT GTGCCCTAAA GGTCATGAAA AAGGCAGTTT TAGGAGCCAA AGAAAAGGTG 420

GTCTTTTATG AGGAAGAAAG GAGGGTTCTG GCTCTAAACA GCAGTCCCTG GATCCCCCAG 480

CTTCTCTATG CATTTCAAGA CAAAGAACAT GTCTACCTGG CAATGGAGTA TTTGCCTGGA 540

GGTGATTTGA TGTCCCTGCT AAATCGATAC GAGGATCAGT TTGATGAGTC CATGGCGCAG 600

TTCTACTTGG CCGAGCTGGT GGAAGCCATT AACAGTGTTC ACCAGCTGGG TTACGTCCAC 660

AGAGACATCA AACCAGAGAA TGTGCTCATT GATCGTACCG GACACATTAA GCTGGCAGAC 720

TTTGGATCGG CTGCCAGGCT CACTGCAAAC AAAACTGTGG CAGTTCCCAC ACTACCTGTC 780

GGCACTCAGG ACTTCCTTTC CCCTGAGATT CTGACAGCCT TAAATGGGGG GCCGAATTGT 840

ACGTACGGGA TTGAATGTGA CTGGTGGTCC CTTGGGGTCA TTGCCTATGA AATGGTTTAT 900

GCCAGGTCGC CATTTTCTGA AGGCACTTCT GCTAAAACAA TTAACAACAT TCTTAACTAT 960

CAGCGATTTC TCAAGTTTCC AGAGGAGCCA CGGGCCAGTA AACAGTTTGT AGACTTGCTA 1020

CAAAAATTAT TGTGTGGAGC CAAAGAACGT CTGGGTTTTC AGGGACTTCG TTGTCACTCG 1080

TTCTTCTCCA GTGTTGACTG GAACAACTTA AGACAAGTTA GACACAGAAC CAGCTTTGTG 1140

CCTCAGCTGC ACACCGAAGA TGACACCTCT AATTTTGAGG AGCCGGAGCA GGCAGCCCCC 1200

CGACCAGGCT CAGCAGCTCA TCAAGGAGCT CTGCCAGTGG GCTTCCAGGG CCAGGACCTT 1260

CCGTTTTTAG GCTGGTTCTT CAGTCGACCA TTAGCCACAT TGGCGAAAGC TGAGTCCACA 1320

TCTACAGGCC TCAACTCTCC TGCTAAGGCT AACTCAATGG AAAAG 1365

Domain Profile

S: 1     feilkviGrGafgevavvrekatekvyamkilkklellkraesaffreerdvlvkadsew  60

         f+++ v+GrG+f+ev++vrekat+++ a+k++kk  l +++++ f++eer vl+ + s+w

Q: 98    FDVRAVVGRGHFSEVQLVREKATGDLCALKVMKKAVLGAKEKVVFYEEERRVLALNSSPW  157

         8999********************************************************

S: 61    ivqlqyafqdekylylvmeylvGGdlltllskyedklpeelarfylaelvlaldsvhelg  120

         i ql yafqd++++yl meyl+GGdl++ll++yed+++e++a+fylaelv a++svh+lg

Q: 158   IPQLLYAFQDKEHVYLAMEYLPGGDLMSLLNRYEDQFDESMAQFYLAELVEAINSVHQLG  217

         ************************************************************

S: 121   yvhrdikpdnilldksGhikladfGsclklnedgtvks.svavGtpdyispevlkalee.  178

         yvhrdikp+n+l+d++GhikladfGs+++l++++tv+  + +vGt d++spe+l+al+

Q: 218   YVHRDIKPENVLIDRTGHIKLADFGSAARLTANKTVAVpTLPVGTQDFLSPEILTALNGg  277

         ************************************873679***************995

S: 179   gkgeygkecdwwslGvilyellvgetpfyaeslvetyskilnhkeslkfpedekvseeak  238

          + +yg ecdwwslGvi+ye+++ ++pf + ++++t ++iln++++lkfpe+ + s+++

Q: 278   PNCTYGIECDWWSLGVIAYEMVYARSPFSEGTSAKTINNILNYQRFLKFPEEPRASKQFV  337

         6889********************************************************

S: 239   dlikklltsreerlgregiedlkkhpff  266

         dl++kll+ ++erlg++g+   ++h+ff

Q: 338   DLLQKLLCGAKERLGFQGL---RCHSFF  362

         ******************9...999998

Domain Sequence
(FASTA)

FDVRAVVGRG HFSEVQLVRE KATGDLCALK VMKKAVLGAK EKVVFYEEER RVLALNSSPW 60

IPQLLYAFQD KEHVYLAMEY LPGGDLMSLL NRYEDQFDES MAQFYLAELV EAINSVHQLG 120

YVHRDIKPEN VLIDRTGHIK LADFGSAARL TANKTVAVPT LPVGTQDFLS PEILTALNGG 180

PNCTYGIECD WWSLGVIAYE MVYARSPFSE GTSAKTINNI LNYQRFLKFP EEPRASKQFV 240

DLLQKLLCGA KERLGFQGLR CHSFF 265

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR017405	; Citron_Rho-interacting_kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013