EKS-TEN-00226

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00226

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/SRPK	744.5	6.6E-224	44	522	479

Status

Unreviewed

Ensembl Protein

ENSTNIP00000009581

UniProt Accession

H3CMV0;

Protein Name

Protein Synonyms/Alias

Gene Name

SRPK1 (2 of 2)

Gene Synonyms/Alias

SRPK1 (2 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000006793	ENSTNIP00000009581	ENSTNIT00000009756

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

524

Protein Sequence
(FASTA)

SPLPEQEEEI LGSDDDEQED PNDYCKGTGG YHHVKIGDFF NGRYHVIRKL GWGHFSTVWL 60

AWDIQEKRFV AMKVVKSAEH YTETALDEIK LLKSVRNTDP SDPNRERVVQ LLDDFKISGV 120

NGTHVCMVFE VLGYHLLKWI IKSNYQGLPL PCVKSIIRQV LQGLDYLHAK CKIIHTDIKP 180

ENILLTVNEP YIKKMAAEAT QWQKSGAAPP SGSAVSTAPA PKPVSHIFIV QRRGSRRSRE 240

EQQPNLSPDE QPQQKSELNN RSADAAVEVN CNGHASTPES GPTPEDKQGD LSTEQDQQQN 300

ANPSESSAES NDQLNNNAEH QSCNGSPGDA DPPQIPAASV SPGAVSLLVN PLDPLNADKL 360

QVKIADLGNA CWVHKHFTDD IQTRQYRSLE VLMGAGYSTP ADIWSTACMA FELATGDYLF 420

EPHSGDDYSR DEDHIALIIE LLGKVPRKLI LAGKYSKEFF TKKGDLRHIT KLKPWGLFDV 480

LVEKYEWSKE EAHNFSSFLL PMLDLVPERR ATAALCLSHP WLTS 524

Nucleotide Sequence
(FASTA)

TCTCCTCTTC CAGAGCAGGA AGAAGAGATC CTGGGCTCTG ATGATGACGA GCAGGAAGAC 60

CCCAATGATT ACTGCAAGGG GACAGGTGGA TATCACCATG TGAAGATTGG GGATTTTTTC 120

AATGGAAGAT ACCATGTGAT CCGTAAGCTG GGCTGGGGCC ACTTCTCCAC TGTGTGGCTG 180

GCCTGGGACA TCCAGGAAAA GCGATTTGTG GCTATGAAGG TTGTAAAAAG TGCTGAGCAT 240

TATACAGAGA CCGCTCTGGA TGAGATCAAG CTGCTGAAGT CTGTGAGGAA CACAGATCCC 300

AGTGACCCCA ACAGAGAGAG AGTGGTGCAG CTTTTGGATG ACTTCAAAAT TTCTGGTGTT 360

AATGGGACTC ATGTGTGTAT GGTGTTTGAA GTGCTGGGAT ATCACCTGCT CAAGTGGATC 420

ATCAAGTCTA ACTACCAGGG ACTGCCTCTG CCCTGTGTGA AAAGCATCAT ACGACAGGTT 480

CTGCAGGGCT TGGACTACCT TCACGCCAAG TGCAAGATCA TCCACACGGA CATTAAACCA 540

GAGAACATTC TACTGACTGT CAACGAGCCC TACATCAAGA AAATGGCTGC CGAAGCTACT 600

CAGTGGCAGA AGTCTGGCGC AGCTCCTCCC TCGGGTTCCG CAGTGAGCAC AGCCCCAGCA 660

CCCAAACCAG TAAGTCATAT TTTTATCGTC CAGAGAAGAG GATCCAGGAG ATCGAGGGAG 720

GAGCAGCAGC CGAACCTGAG TCCTGATGAG CAGCCCCAGC AAAAGTCAGA GCTAAATAAC 780

CGGAGTGCCG ATGCAGCCGT GGAGGTGAAC TGTAACGGAC ATGCCTCCAC CCCAGAGAGT 840

GGCCCCACTC CTGAGGACAA ACAGGGTGAC CTGTCGACGG AGCAGGACCA GCAGCAGAAC 900

GCCAACCCGT CAGAAAGCAG CGCCGAAAGC AACGACCAGC TGAATAACAA CGCCGAGCAT 960

CAGAGCTGTA ACGGTTCCCC AGGAGACGCC GACCCCCCGC AGATCCCTGC CGCCTCTGTC 1020

TCCCCAGGAG CTGTCAGTTT GTTAGTAAAC CCTCTGGACC CTCTTAATGC CGACAAGCTG 1080

CAGGTGAAGA TAGCTGACTT GGGCAATGCC TGCTGGGTGC ACAAACATTT CACAGATGAC 1140

ATCCAGACTC GGCAGTATCG TTCACTGGAG GTGCTGATGG GAGCTGGATA CAGCACCCCC 1200

GCAGATATCT GGAGCACCGC CTGCATGGCC TTTGAGCTGG CTACTGGAGA TTATCTGTTT 1260

GAACCTCACT CGGGGGATGA TTACTCCAGA GATGAAGATC ACATAGCCCT GATTATCGAG 1320

CTGCTGGGGA AAGTCCCCCG AAAGCTAATT CTGGCAGGCA AATACTCTAA GGAGTTTTTC 1380

ACCAAGAAAG GCGATTTGCG TCACATCACC AAGCTGAAGC CGTGGGGGTT GTTCGATGTT 1440

TTGGTAGAAA AGTACGAGTG GTCAAAGGAA GAAGCTCATA ACTTCAGCAG TTTTCTGCTG 1500

CCAATGCTGG ACCTGGTTCC TGAGAGAAGG GCCACAGCAG CCCTCTGCCT CTCTCACCCG 1560

TGGCTCACGT CCTAG 1575

Domain Profile

S: 1     yhvirkLGWGhfstvWLawdlqekrfvalkvvksaehytetaldeikllksvresdpsdp  60

         yhvirkLGWGhfstvWLawd+qekrfva+kvvksaehytetaldeikllksvr++dpsdp

Q: 44    YHVIRKLGWGHFSTVWLAWDIQEKRFVAMKVVKSAEHYTETALDEIKLLKSVRNTDPSDP  103

         9***********************************************************

S: 61    krekvvqllddfkisGvnGvhvclvfevLGenLlkliiksnyrGlpleqvkkiirqvLeg  120

         +re+vvqllddfkisGvnG+hvc+vfevLG +Llk+iiksny+Glpl++vk+iirqvL+g

Q: 104   NRERVVQLLDDFKISGVNGTHVCMVFEVLGYHLLKWIIKSNYQGLPLPCVKSIIRQVLQG  163

         ************************************************************

S: 121   LdylhekCkiihtdikPenvLlavddeyirrlaaeatewqkagakppsgsavstapqkka  180

         Ldylh kCkiihtdikPen+Ll+v++ yi+++aaeat+wqk+ga ppsgsavstap +k+

Q: 164   LDYLHAKCKIIHTDIKPENILLTVNEPYIKKMAAEATQWQKSGAAPPSGSAVSTAPAPKP  223

         ************************************************************

S: 181   ieklsknkkkklkkkqkrqaellekrl..qeleeleaaeanseaedqelkedaekgelee  238

         + ++   +++  ++ + +q+  l      q+  el+   a++ +e + + + ++ ++

Q: 224   VSHIFIVQRRGSRRSREEQQPNLSPDEqpQQKSELNNRSADAAVEVNCNGHASTPESGPT  283

         **********99999999999886555004555555333333333322222222222222

S: 239   ieadveeevanedeaseeee........essltsssdaesksgelseastellsesleql  290

          e d++ ++ +e++++++ +        + +l + ++++s +g+  +a  + +     ++

Q: 284   PE-DKQGDLSTEQDQQQNANpsessaesNDQLNNNAEHQSCNGSPGDADPPQIPA--ASV  340

         22.2222222222222222211111111223333333333333333333332222..222

S: 291   acgsvls......vnplepknadkikvkiadLGnaCwvhkhftediqtrqyrslevliGa  344

         +     +      vnpl+p nadk++vkiadLGnaCwvhkhft+diqtrqyrslevl+Ga

Q: 341   S-----PgavsllVNPLDPLNADKLQVKIADLGNACWVHKHFTDDIQTRQYRSLEVLMGA  395

         3.....2444445***********************************************

S: 345   gygtpadiWstaClafeLatGdyLfephsgedysrdedhiakiiellGkiPrklilkGky  404

         gy+tpadiWstaC+afeLatGdyLfephsg+dysrdedhia iiellGk+Prklil+Gky

Q: 396   GYSTPADIWSTACMAFELATGDYLFEPHSGDDYSRDEDHIALIIELLGKVPRKLILAGKY  455

         ************************************************************

S: 405   sreffnkkgeLrhitkLkpwsLlevLvekyewskeeaaefsdfLlPmleldpekrasaae  464

         s+eff+kkg+LrhitkLkpw+L++vLvekyewskeea++fs+fLlPml+l+pe+ra+aa

Q: 456   SKEFFTKKGDLRHITKLKPWGLFDVLVEKYEWSKEEAHNFSSFLLPMLDLVPERRATAAL  515

         ************************************************************

S: 465   clkhpwL  471

         cl hpwL

Q: 516   CLSHPWL  522

         ******8

Domain Sequence
(FASTA)

YHVIRKLGWG HFSTVWLAWD IQEKRFVAMK VVKSAEHYTE TALDEIKLLK SVRNTDPSDP 60

NRERVVQLLD DFKISGVNGT HVCMVFEVLG YHLLKWIIKS NYQGLPLPCV KSIIRQVLQG 120

LDYLHAKCKI IHTDIKPENI LLTVNEPYIK KMAAEATQWQ KSGAAPPSGS AVSTAPAPKP 180

VSHIFIVQRR GSRRSREEQQ PNLSPDEQPQ QKSELNNRSA DAAVEVNCNG HASTPESGPT 240

PEDKQGDLST EQDQQQNANP SESSAESNDQ LNNNAEHQSC NGSPGDADPP QIPAASVSPG 300

AVSLLVNPLD PLNADKLQVK IADLGNACWV HKHFTDDIQT RQYRSLEVLM GAGYSTPADI 360

WSTACMAFEL ATGDYLFEPH SGDDYSRDED HIALIIELLG KVPRKLILAG KYSKEFFTKK 420

GDLRHITKLK PWGLFDVLVE KYEWSKEEAH NFSSFLLPML DLVPERRATA ALCLSHPWL 479

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Caenorhabditis elegans"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Drosophila melanogaster"; ?>Gasterosteus aculeatus"; ?>Microcebus murinus"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>