EKS-TEN-00082

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00082

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	384.6	2.9E-115	141	422	282

Status

Unreviewed

Ensembl Protein

ENSTNIP00000010184

UniProt Accession

H3CPK1;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK18

Gene Synonyms/Alias

CDK18;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000007379	ENSTNIP00000010184	ENSTNIT00000010365

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

471

Protein Sequence
(FASTA)

TMNKMKNFKR RFSLSVPRTE TIEENDFTGQ INQLNIQHIQ DPAPDRLGPP SQDVSPVSPE 60

PTTPGAQSPS HLLYHSKTQH RRFSMEDVSK RMSLPMDIRL PPEFLKKLQP ENENSPLCKP 120

LSRMSRRASL SDIGFGKLET YVKLGKLGEG TYATVFKGRS KLTENLVALK EIRLEHDEGA 180

PCTAIREVSL LKNLKHANIV TLHDIIHTER CLTLVFEYLD SDLKHYLDNC GNLMSMHNVK 240

IFMFQLLRGL SYCHKRKILH RDLKPQNLLI NDKGELKLAD FGLARAKSVP TKTYSNEVVT 300

LWYRPPDVLL GSTEYSTPID MWGVGCILYE MATGRPMFPG ATVKEELHLI FRLMGTPTED 360

SWPGVSSNEE FRSYLFPQYR AQNLINHVPR LDTEGIDLLC ALLKFDTRSR ISSEAALRHS 420

YFLSLGENIH NLPDTASVFS LREVQLQKDP GHRSSVFQPL VRGKNRRQSI F 471

Nucleotide Sequence
(FASTA)

ACCATGAACA AGATGAAGAA CTTTAAACGT CGTTTTTCTC TCTCGGTTCC CCGCACCGAG 60

ACCATCGAGG AGAACGACTT CACTGGCCAG ATCAACCAGC TCAACATCCA GCACATTCAG 120

GACCCAGCAC CGGACAGACT GGGCCCTCCG TCCCAGGACG TCAGCCCGGT CAGTCCAGAG 180

CCAACAACGC CGGGGGCCCA GTCTCCGTCC CACCTCCTCT ATCACAGCAA GACGCAGCAC 240

AGGCGCTTCT CCATGGAGGA CGTCAGCAAG CGTATGTCTC TGCCCATGGA CATCCGGCTG 300

CCTCCAGAGT TCCTGAAGAA GCTGCAGCCG GAGAACGAAA ACTCGCCGCT CTGCAAACCT 360

CTCAGTCGCA TGTCTCGGCG CGCCTCGCTG TCTGACATAG GCTTCGGAAA ACTGGAGACG 420

TATGTGAAGC TGGGGAAACT GGGAGAAGGG ACGTACGCCA CGGTCTTCAA AGGGAGGAGC 480

AAACTCACCG AGAACCTGGT GGCCTTGAAG GAGATCAGGC TGGAGCATGA CGAGGGGGCC 540

CCCTGCACCG CCATCAGAGA AGTGTCGCTG CTGAAGAACC TGAAACACGC CAACATCGTC 600

ACGCTTCACG ACATCATCCA CACCGAACGC TGCCTCACTC TGGTGTTTGA GTACCTGGAC 660

AGCGACCTCA AACACTACCT GGACAACTGT GGGAATCTGA TGAGCATGCA CAACGTCAAG 720

ATTTTCATGT TCCAGCTCCT ACGTGGTCTC TCCTACTGCC ACAAGAGGAA GATCCTGCAC 780

CGGGACCTGA AGCCTCAGAA CCTGCTCATC AACGACAAAG GGGAGCTGAA ACTGGCCGAC 840

TTCGGTCTGG CCCGAGCCAA GTCTGTTCCC ACAAAGACCT ACTCCAATGA GGTGGTGACT 900

CTGTGGTACC GGCCCCCCGA TGTGCTCCTG GGCTCCACAG AGTACTCCAC GCCCATCGAC 960

ATGTGGGGCG TGGGGTGTAT CCTCTACGAA ATGGCCACCG GCCGTCCGAT GTTTCCTGGA 1020

GCCACAGTGA AGGAGGAGCT GCACTTGATC TTCAGGCTGA TGGGAACCCC CACGGAGGAC 1080

AGCTGGCCTG GGGTCAGCAG TAACGAGGAG TTCAGGTCCT ACCTCTTCCC TCAGTACAGA 1140

GCGCAGAACC TCATCAACCA CGTGCCCAGG TTGGACACGG AGGGGATCGA CCTGCTGTGT 1200

GCGCTGCTGA AGTTTGACAC CAGGAGCCGA ATCAGCTCTG AGGCGGCGCT GCGACACTCC 1260

TACTTCCTGA GTCTGGGGGA GAACATTCAC AATCTGCCAG ACACTGCTTC AGTATTTTCC 1320

CTCAGAGAGG TGCAGCTCCA GAAGGACCCG GGACATCGCA GCTCCGTCTT CCAGCCTTTA 1380

GTTCGAGGAA AAAACCGAAG ACAAAGTATT TTCTAG 1416

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y kl k+geGty++v+k+++k t+++vAlK+irle++ eg p+ta+rE+sllk+lkh+ni

Q: 141   YVKLGKLGEGTYATVFKGRSKLTENLVALKEIRLEHD-EGAPCTAIREVSLLKNLKHANI  199

         78999******************************99.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++++ +++ l+Lvfe+l++dLk++l+++ +  +s+++vk +++qll+gl+y+H++k

Q: 200   VTLHDIIH-TERCLTLVFEYLDSDLKHYLDNCGN-LMSMHNVKIFMFQLLRGLSYCHKRK  257

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         ilHRDlKpqNlLi+++g+lklaDfGlara s+p+kty++evvTlwYr+P++Llg++eYst

Q: 258   ILHRDLKPQNLLINDKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST  317

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

          +D+W+vgcil e++t +p+f+g + +++l+ if+l+gtp+e++wp+vs+ +e++ + fp

Q: 318   PIDMWGVGCILYEMATGRPMFPGATVKEELHLIFRLMGTPTEDSWPGVSSNEEFRsYLFP  377

         *******************************************************899**

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         ++++++l ++v++l+++++dll  ll++d ++Ris+++al+h+yf

Q: 378   QYRAQNLINHVPRLDTEGIDLLCALLKFDTRSRISSEAALRHSYF  422

         ********************************************9

Domain Sequence
(FASTA)

YVKLGKLGEG TYATVFKGRS KLTENLVALK EIRLEHDEGA PCTAIREVSL LKNLKHANIV 60

TLHDIIHTER CLTLVFEYLD SDLKHYLDNC GNLMSMHNVK IFMFQLLRGL SYCHKRKILH 120

RDLKPQNLLI NDKGELKLAD FGLARAKSVP TKTYSNEVVT LWYRPPDVLL GSTEYSTPID 180

MWGVGCILYE MATGRPMFPG ATVKEELHLI FRLMGTPTED SWPGVSSNEE FRSYLFPQYR 240

AQNLINHVPR LDTEGIDLLC ALLKFDTRSR ISSEAALRHS YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013