EKS-TEN-00307

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00307

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	338.1	3.3E-101	26	278	253

Status

Unreviewed

Ensembl Protein

ENSTNIP00000010300

UniProt Accession

H3CPW6;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKAA1

Gene Synonyms/Alias

PRKAA1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000007491	ENSTNIP00000010300	ENSTNIT00000010481

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

581

Protein Sequence
(FASTA)

TLQQGHCGKM ATDKNKHEGR VKIGHYILGD TLGVGTFGKV KVGQHELTKH QVAVKILNRQ 60

KIRSLDVVGK IRREIQNLKL FRHPHIIKLY QVISTPTDIF MVMEYVSGGE LFDYICKNGK 120

LDEKESRRLF QQIISAVDYC HRHMVVHRDL KPENVLLDAH MNAKIADFGL SNMMSDGEFL 180

RTSCGSPNYA APEVISGRLY AGPEVDIWSS GVILYALLCG TLPFDDDHVP TLFKKICDGI 240

FFTPQYLNPS VISLLKHMLQ VDPMKRATIR EIREDEWFKQ DLPKYLFPED PSYSNNMIDD 300

EALKEVCEKF ECAEEEVLAC IYSRNHQDPL AVAYHLIIDN RRIMNEAKDF YLASSPPDSF 360

LDDQHLTSAG VVTGIVKPHP ERVPFLVAET LPRPRHKLEE LNPQKSKHQG VRRAKWHLGI 420

RSQSRPNDIM SEVCRAMKQL DYEWKVVNPY YLRVRRKNPI TGMQTKMSLQ LYQVDSRTYL 480

LDFRSIDDDM LETKSGTATP LRSGSVSNYR TTVRTDADAT DGPVTSNLVH SAKAAEGSLA 540

SSLASSTDST GGVDNTSVPR PGSHTIEFFE MCANLIKLLA R 581

Nucleotide Sequence
(FASTA)

ACTCTGCAGC AAGGCCACTG CGGGAAGATG GCGACGGATA AAAACAAACA TGAAGGAAGA 60

GTGAAAATTG GGCATTACAT TCTTGGGGAC ACACTTGGAG TTGGAACATT CGGAAAGGTT 120

AAAGTGGGCC AACATGAGCT AACTAAGCAC CAGGTAGCGG TGAAGATCCT GAACAGGCAG 180

AAGATCCGCA GTTTAGATGT GGTGGGAAAG ATCCGCAGAG AGATCCAGAA CCTCAAGCTT 240

TTTCGGCATC CTCATATAAT TAAACTGTAT CAGGTAATTA GCACCCCTAC TGATATCTTC 300

ATGGTGATGG AGTATGTCTC TGGAGGCGAG CTCTTTGATT ACATTTGCAA AAATGGAAAG 360

TTGGATGAGA AAGAGAGCCG TCGGCTGTTC CAGCAGATTA TTTCGGCTGT GGACTACTGC 420

CACAGACACA TGGTGGTACA CCGGGACCTC AAGCCTGAGA ACGTGCTGCT CGATGCACAC 480

ATGAATGCCA AAATTGCAGA CTTTGGTTTG TCAAACATGA TGTCCGATGG AGAGTTCTTG 540

CGTACAAGCT GCGGCTCTCC AAACTACGCT GCGCCTGAGG TTATCTCAGG AAGGTTATAC 600

GCTGGTCCAG AGGTGGACAT CTGGAGCAGC GGGGTCATTC TTTATGCCCT ACTGTGTGGG 660

ACGCTTCCAT TTGACGACGA CCACGTGCCA ACTCTCTTTA AGAAGATCTG CGATGGGATA 720

TTTTTCACTC CCCAGTATCT GAACCCTTCG GTAATCAGCC TCCTTAAGCA CATGCTGCAG 780

GTGGACCCCA TGAAGAGAGC CACCATCAGA GAGATCCGAG AGGACGAGTG GTTCAAACAG 840

GACCTACCCA AGTACCTGTT CCCCGAAGAC CCCTCCTACA GCAACAACAT GATCGACGAC 900

GAGGCCCTGA AGGAAGTGTG CGAGAAGTTC GAGTGCGCGG AGGAGGAGGT CCTGGCCTGC 960

ATCTACAGTC GCAACCACCA GGACCCCCTG GCCGTCGCCT ACCACCTCAT CATCGACAAC 1020

CGCCGCATCA TGAACGAAGC CAAGGACTTC TACCTGGCAT CCAGCCCCCC CGACTCCTTC 1080

CTGGACGACC AGCACCTGAC CTCAGCGGGA GTGGTCACGG GCATCGTCAA ACCCCACCCG 1140

GAGCGCGTCC CCTTCCTGGT GGCAGAGACG CTCCCCAGGC CTCGGCACAA GTTGGAGGAA 1200

CTGAACCCGC AGAAGTCGAA GCACCAGGGC GTCAGAAGGG CCAAGTGGCA CCTGGGCATC 1260

CGCAGCCAGA GCAGGCCCAA CGATATCATG TCGGAAGTGT GTCGCGCCAT GAAACAGTTG 1320

GATTATGAGT GGAAGGTCGT GAATCCATAT TATCTACGTG TCAGAAGGAA AAATCCCATC 1380

ACGGGCATGC AGACCAAGAT GAGCCTCCAG CTCTACCAGG TGGACAGTAG AACCTACCTC 1440

CTCGACTTCC GTAGCATAGA CGATGACATG TTGGAAACAA AATCGGGAAC TGCTACACCT 1500

CTGCGCTCCG GCTCTGTCAG CAACTACCGC ACCACTGTTA GGACCGACGC CGACGCGACG 1560

GACGGCCCGG TCACGTCCAA CCTGGTGCAC TCGGCCAAGG CCGCAGAAGG TTCCCTAGCG 1620

TCATCGCTCG CTTCATCCAC TGACTCGACG GGAGGCGTTG ACAACACATC AGTGCCACGA 1680

CCTGGAAGCC ACACCATTGA GTTCTTTGAG ATGTGCGCAA ACCTTATTAA GTTACTTGCA 1740

CGATAG 1746

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y l++tlG g+fgkVk+ +h++tk++vavKi++++k+ s + + ki+rEi+ lk ++hp+

Q: 26    YILGDTLGVGTFGKVKVGQHELTKHQVAVKILNRQKIrSLDVVGKIRREIQNLKLFRHPH  85

         8899********************************96667788****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         iikl++vi+t +++++v+ey+sggeLfdyi ++g+l+eke+r+lf+q++sav+Y+h++ +

Q: 86    IIKLYQVISTPTDIFMVMEYVSGGELFDYICKNGKLDEKESRRLFQQIISAVDYCHRHMV  145

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlKpeN+lld+++n kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp+v

Q: 146   VHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV  205

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D+Ws Gv+Lyal++g+lPfd++++ +l++ki +g + +p++l+++++sLl+++L+vdp k

Q: 206   DIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFFTPQYLNPSVISLLKHMLQVDPMK  265

         ************************************************************

S: 240   Ratieeilkhewl  252

         Rati+ei+++ew+

Q: 266   RATIREIREDEWF  278

         ************7

Domain Sequence
(FASTA)

YILGDTLGVG TFGKVKVGQH ELTKHQVAVK ILNRQKIRSL DVVGKIRREI QNLKLFRHPH 60

IIKLYQVIST PTDIFMVMEY VSGGELFDYI CKNGKLDEKE SRRLFQQIIS AVDYCHRHMV 120

VHRDLKPENV LLDAHMNAKI ADFGLSNMMS DGEFLRTSCG SPNYAAPEVI SGRLYAGPEV 180

DIWSSGVILY ALLCGTLPFD DDHVPTLFKK ICDGIFFTPQ YLNPSVISLL KHMLQVDPMK 240

RATIREIRED EWF 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013