EKS-TEN-00497

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00497

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	311.6	5.8E-93	614	878	265

Status

Unreviewed

Ensembl Protein

ENSTNIP00000010372

UniProt Accession

H3CQ38;

Protein Name

Protein Synonyms/Alias

Gene Name

YSK4

Gene Synonyms/Alias

YSK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000007562	ENSTNIP00000010372	ENSTNIT00000010553

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

901

Protein Sequence
(FASTA)

MFRRIKVLHA QDILPTLSPK LLEPISRRAE EHAGLPVLRD RAPLKFIRNI SLSSWTHPRT 60

ERPRGRPRTG PLATKGGSEE SGSSSSSIDL EDEGDSEAGD GGLVRMTVGK IPLNHRSAYS 120

GKAISASRLS PEQGPDFLCG GKVSNPKQPA HRQTLRSTVE RGKTGNFNAS ATSEFEEEVK 180

SNAGQTPEAE VSHEEKHEAQ GEPDECCEGN LRRDLLTKPD FQVESREDVK LQTEEKSPSS 240

NLSESNTGVS GDSRKVASQK ERRMRAACSQ RSNTGTNQRS FNKNSRSPSS HCDISSPLPK 300

KKGSDKTRRL KVKVSSNRVP QLPALRQLKD SHLLKRPSFA GLTRSKSAVD VITYNDMFQR 360

IQNGGGGPAI YEMFAGPLYD NLRASSSCDQ VQDRKVQSAM AACRPLKHTH EGKSQAAQVE 420

RTVASANDRP KHGSSRRKNI TVSCKKTKKI NSTNKHDGRE KAESALPGGP DYSHAQEKGK 480

EEMLSTIEES ATFKSDIRTL TVAAGSSRNI LETKGNTWEP LRGSSPAIMS PVYQKFLDDV 540

GDGPLTDDLL QCLAEELISL DERDASTGTC ETEGPSQEKP DTENDPGSGK QEPSKPEPSA 600

AGCDPALADD AITWTKGEVL GKGAYGIVYC GLTSHGQLVA VKQVSLDASD PDAAEGEYAR 660

LQGEVELLKT LRHANIVGFL GTSFHQQVVS IFMEYIPGGS IASILHRFGP LPERVLALYT 720

KQILEGVAYL HLNKVIHRDL KGNNIMLMPT GIVKLIDFGC ARRLSCLSHN ASNSADLLKS 780

VHGTPYWMAP EVINDSGYGR KSDIWSVGCT VFEMATGKPP LAHMDKMAAL FYIGAQRGIM 840

PSLPNGFSET AKDFVETCLI RDQRLRPPAK HLLKHPFIHQ NTAIVNTSQA LKIRCSGPTC 900

S 901

Nucleotide Sequence
(FASTA)

ATGTTCAGGC GTATAAAAGT TCTTCATGCA CAGGATATCT TGCCGACTTT GAGTCCCAAG 60

TTGTTGGAAC CAATAAGCAG GAGGGCTGAG GAACATGCAG GTCTACCAGT GCTCAGAGAT 120

CGCGCTCCTC TGAAGTTCAT CAGGAACATC TCGCTCTCCT CCTGGACCCA TCCAAGGACT 180

GAAAGGCCAA GGGGTCGCCC GCGGACTGGA CCCCTGGCTA CGAAGGGCGG CAGCGAGGAG 240

AGCGGTTCCA GCAGCAGTTC CATCGATCTG GAAGACGAAG GGGACAGCGA AGCTGGAGAT 300

GGAGGTCTGG TTCGGATGAC AGTTGGGAAA ATTCCACTAA ACCACAGATC AGCATATAGT 360

GGAAAAGCCA TCAGTGCTTC AAGACTCAGT CCAGAACAAG GGCCAGACTT TCTGTGTGGA 420

GGCAAAGTGT CAAATCCAAA GCAGCCTGCT CACAGGCAGA CCCTCAGAAG TACTGTTGAA 480

CGAGGAAAAA CTGGGAATTT TAATGCCTCT GCAACATCCG AGTTTGAGGA GGAGGTCAAG 540

AGCAACGCAG GCCAAACACC AGAGGCGGAG GTTAGCCACG AGGAAAAACA CGAGGCTCAG 600

GGTGAACCTG ACGAATGCTG TGAAGGAAAT CTGAGACGTG ATCTTCTCAC AAAACCGGAT 660

TTTCAGGTTG AGAGCCGAGA GGATGTCAAG TTACAAACAG AGGAAAAATC CCCATCGTCA 720

AACCTTTCAG AATCGAACAC AGGAGTCTCA GGAGACAGCA GGAAAGTTGC CAGCCAGAAG 780

GAGAGAAGAA TGCGGGCAGC CTGTTCACAA AGGTCAAATA CTGGAACCAA CCAGCGGTCC 840

TTCAACAAGA ACAGCAGGAG CCCCAGCAGT CACTGTGACA TCAGCTCACC TCTCCCGAAA 900

AAGAAGGGCT CTGATAAGAC CAGAAGGTTA AAGGTCAAGG TCAGCAGCAA CAGGGTTCCA 960

CAGCTTCCAG CGCTGAGGCA GCTGAAGGAC AGCCATCTGT TGAAAAGACC CAGTTTTGCG 1020

GGGTTAACGA GGTCCAAGTC TGCCGTGGAC GTCATTACCT ACAACGACAT GTTTCAGCGG 1080

ATACAGAACG GGGGCGGCGG ACCGGCGATC TATGAGATGT TTGCCGGTCC TCTCTACGAC 1140

AACCTGAGAG CCTCCAGCTC CTGCGACCAA GTCCAGGACA GGAAGGTTCA ATCTGCGATG 1200

GCCGCGTGCA GACCTTTGAA ACACACGCAC GAGGGGAAAA GCCAAGCCGC TCAAGTGGAG 1260

AGGACAGTGG CTTCGGCTAA CGACAGACCA AAACATGGAT CTTCCAGGCG GAAAAACATC 1320

ACAGTTTCAT GCAAAAAAAC CAAGAAAATT AATTCTACCA ATAAACACGA TGGGCGTGAA 1380

AAGGCTGAGT CGGCTCTCCC CGGGGGTCCT GATTACTCTC ATGCCCAAGA AAAGGGTAAA 1440

GAAGAGATGT TATCAACCAT AGAGGAGTCT GCTACATTCA AATCTGACAT CAGGACACTA 1500

ACGGTTGCAG CAGGTTCCTC TAGAAACATT CTAGAAACCA AGGGCAACAC CTGGGAACCT 1560

TTAAGGGGCA GCAGCCCCGC CATCATGTCG CCAGTTTACC AGAAGTTCCT GGATGACGTG 1620

GGTGACGGGC CGCTGACCGA TGACCTGCTG CAATGCCTGG CAGAAGAGCT GATTTCTCTG 1680

GATGAGAGGG ACGCGTCCAC TGGTACGTGC GAAACCGAGG GACCAAGTCA AGAAAAGCCT 1740

GATACGGAAA ACGATCCAGG ATCTGGAAAA CAAGAACCTT CTAAGCCTGA ACCAAGCGCG 1800

GCTGGCTGTG ACCCCGCGTT GGCCGATGAT GCGATCACCT GGACGAAGGG CGAAGTGCTC 1860

GGCAAAGGAG CCTACGGGAT AGTCTACTGT GGTCTGACCA GCCACGGCCA GCTGGTCGCC 1920

GTGAAGCAGG TGAGCCTGGA TGCCTCGGAC CCAGACGCCG CGGAGGGAGA ATACGCTCGT 1980

CTGCAGGGGG AAGTGGAGCT CCTGAAAACC CTTAGACACG CCAACATTGT GGGCTTTTTG 2040

GGGACCTCGT TTCATCAGCA GGTGGTGTCC ATCTTCATGG AGTACATCCC CGGAGGCTCC 2100

ATCGCGAGCA TCCTTCACAG GTTTGGTCCC CTGCCAGAGC GCGTCCTGGC TCTCTACACC 2160

AAGCAGATTC TGGAGGGAGT CGCCTACCTT CACCTGAACA AGGTGATTCA CCGCGACTTG 2220

AAGGGGAACA ACATCATGCT GATGCCCACG GGAATCGTCA AATTGATAGA CTTCGGCTGC 2280

GCGCGCCGCC TCAGCTGCCT CAGCCACAAC GCCAGCAACA GTGCAGACCT GCTGAAGTCT 2340

GTCCATGGCA CCCCCTACTG GATGGCACCG GAGGTTATCA ACGACTCGGG ATACGGCAGA 2400

AAGTCGGACA TATGGAGCGT CGGCTGTACA GTGTTTGAGA TGGCTACAGG GAAGCCACCA 2460

CTGGCACACA TGGACAAGAT GGCCGCCTTG TTCTACATCG GGGCTCAGAG GGGTATCATG 2520

CCCTCCCTGC CAAATGGGTT TTCAGAAACG GCCAAGGACT TTGTCGAGAC CTGTCTGATA 2580

CGTGACCAGA GACTGCGGCC GCCTGCCAAA CATCTGCTGA AACATCCTTT CATCCACCAA 2640

AACACGGCCA TCGTGAACAC AAGCCAAGCG CTAAAAATCC GCTGCTCCGG TCCAACATGC 2700

AGCTGA 2706

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikpekksekk.evkalkeEikllkelk  59

         w+k+ev+gkG++g vy++l+ + g+l+avK+v+++  + ++ + e+  l+ E++llk+l+

Q: 614   WTKGEVLGKGAYGIVYCGLT-SHGQLVAVKQVSLDASDPDAAEgEYARLQGEVELLKTLR  672

         89*****************9.7899*********9877666666****************

S: 60    HenivkyyGveveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLHe  119

         H niv ++G++ +++ ++if+Ey++gGs++s+l+++g+l e+v+  ytkqileg+ayLH

Q: 673   HANIVGFLGTSFHQQVVSIFMEYIPGGSIASILHRFGPLPERVLALYTKQILEGVAYLHL  732

         ************************************************************

S: 120   kkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaae....lesltGtlaymaPEv  175

         +k++HRD+Kg+Ni+l+ +g+vkl DFG+++rl+ l+++a++    l+s++Gt+++maPEv

Q: 733   NKVIHRDLKGNNIMLMPTGIVKLIDFGCARRLSCLSHNASNsadlLKSVHGTPYWMAPEV  792

         ********************************999888777778889*************

S: 176   ikkkekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakk.tkPeipeklse  234

         i+ +  gygrk+DiWs+gc+v+em+tgk+P a++ +++a++f +ga++ ++P++p+ +se

Q: 793   INDS--GYGRKSDIWSVGCTVFEMATGKPPLAHM-DKMAALFYIGAQRgIMPSLPNGFSE  849

         *888..****************************.99********99989**********

S: 235   egkdflekcleldpkkrpsaeeLLkhefl  263

         ++kdf+e+cl +d++ rp a++LLkh+f+

Q: 850   TAKDFVETCLIRDQRLRPPAKHLLKHPFI  878

         ***************************96

Domain Sequence
(FASTA)

WTKGEVLGKG AYGIVYCGLT SHGQLVAVKQ VSLDASDPDA AEGEYARLQG EVELLKTLRH 60

ANIVGFLGTS FHQQVVSIFM EYIPGGSIAS ILHRFGPLPE RVLALYTKQI LEGVAYLHLN 120

KVIHRDLKGN NIMLMPTGIV KLIDFGCARR LSCLSHNASN SADLLKSVHG TPYWMAPEVI 180

NDSGYGRKSD IWSVGCTVFE MATGKPPLAH MDKMAALFYI GAQRGIMPSL PNGFSETAKD 240

FVETCLIRDQ RLRPPAKHLL KHPFI 265

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013