EPS-TEN-00038

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-TEN-00038

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	170.5	6.4E-50	719	965	247

Status

Unreviewed

Ensembl Protein

ENSTNIP00000004642

UniProt Accession

H3CVC4;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000009340	ENSTNIP00000012208	ENSTNIT00000012399
ENSTNIG00000009340	ENSTNIP00000004642	ENSTNIT00000004785

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

1224

Protein Sequence
(FASTA)

STSTTVEELC AQRDGRSLYV QLHGDLVRRL EASERPLQMV YDYLAAMGYA DPARVQQEAA 60

NSDLSCLIRF YRECPANADQ QERTLLKGVF SVRKGKSQLH KWAERQVILC GTCLIVASVK 120

DSLTGKMHIL PLVGGKVEEV KRRQHCLMFS SAGSQAQTYF VNFDTLAEYQ RWQRQASKVV 180

SQTVSMVDLS CYSLEEVPEY LFYSQDVTHL NLRHNFMSHQ GPGGLLNLPR FSQLKSLNLS 240

HNRLGVFPEC VCEIPTLSEL NLSCNNLKNI PVKIGNLQSL QTLSLDGNHL SFLPDEVGDL 300

AQLNSLGLSF NNFSHIPTVL ERLAAVDRLA MAGNRVESLH LCALARMSHL KSVDLRLNGL 360

KWVKNDSLEV VSQVTQMDLR DNCLDTLDLS SVSNLEALHC QRNQLGSLAL SGFTLRTINV 420

SGNRLTTVNV YPVPNQLTHM DLSQNLLEYL PDWVSDCRKI EMLDITHNLL SELPSRLLNS 480

LSLRKLLAGN NHLQRVPDLL DHIPLEVLDL QHNRLVELPD SLFSKALNLK YLNVSANALG 540

KIPPSSESEE SLSTLQELYL TGNSLTENCG ALLVGHRNLR VLHIAYNQLL SFPASKLSRL 600

EQLEELNLSG NKLKTIPSTV SSCKRLHTLI AHSNHLTVFP EILTLPEIKF VDLSCNELTE 660

IQVPDSLPAT LQELDLTGNS SLMLEHNTLN LFSNIATLKL DQKSAATAAD VLSASTPWSH 720

GYSEMSGHRN KLCVSVLAVD HFGDGAEACY GVFDGDRNEE VPRLLQCTMG DVLCEELQHS 780

GVDSVYMCNT FLTSHRKLGM AGQKLGASAL LCYLHREQSD SGANFSLTVA NVGACQAVLC 840

RDGRPVPLSK VYSLENSTEE MERVKLSKAI ITEDNKVSGV TCCSRLLGCS YLSPWVLPKP 900

WVHTEHLRPQ DEFLIMGNRA LFERVSHQEA VRTVQAVQDP RAAAKKLCTL AQSYGCKDNI 960

QALVVSLHIS EDGCTCEPPF SVPDPRCPPP ASVPVSAASA STSADAATLS SSSGVVSEFS 1020

SETSASEVGS EAGSTASDEH SGRPERRCSL HPAPTLCGIM IPGSAGAGPH QGLFQRQPSS 1080

ATFSSNQSDN GLDSDDEAPL EGVISNGSRL EVEVDIHCCA FQLRSECPKD LKLETQGCDY 1140

GCLMAVCGRE IADLKKSPST FSLFGKKLSN GSVVAPEDSH NIIEVALEAP KKKSGYFTAP 1200

AQPDPEDQLV VPPSLEQEVR EQLR 1224

Nucleotide Sequence
(FASTA)

TCCACGAGCA CCACGGTGGA GGAGCTGTGT GCCCAGAGGG ACGGACGGAG CCTCTACGTC 60

CAGCTTCACG GAGACCTCGT GAGGAGGCTG GAAGCCAGCG AGCGTCCCCT CCAGATGGTG 120

TACGACTACC TGGCTGCCAT GGGCTATGCG GACCCCGCGC GAGTGCAGCA GGAGGCGGCC 180

AACTCGGACC TGAGCTGCCT GATTCGCTTC TACAGGGAAT GTCCGGCGAA TGCGGACCAG 240

CAGGAGCGGA CCCTGCTGAA GGGCGTTTTC AGCGTCCGGA AGGGCAAGTC GCAGCTGCAC 300

AAGTGGGCGG AGCGGCAGGT CATCCTCTGC GGCACCTGTC TCATCGTGGC CTCCGTCAAG 360

GACAGCTTGA CAGGGAAGAT GCACATCCTG CCCCTGGTGG GGGGAAAGGT GGAAGAGGTG 420

AAGCGGAGGC AGCACTGCCT GATGTTCAGC TCCGCCGGTT CCCAGGCGCA GACCTACTTT 480

GTCAACTTTG ACACACTGGC TGAGTATCAG AGGTGGCAGC GGCAGGCGTC AAAAGTGGTT 540

TCTCAGACAG TCAGCATGGT TGACCTGTCC TGTTACAGCC TGGAGGAGGT GCCTGAATAT 600

CTCTTTTACA GCCAGGATGT CACCCACCTC AACCTGCGAC ACAATTTCAT GAGCCATCAG 660

GGACCCGGAG GTCTACTCAA CCTGCCCAGG TTTTCCCAGC TGAAGAGCCT GAACTTGTCT 720

CACAACCGAC TGGGTGTTTT CCCCGAGTGT GTGTGTGAGA TCCCCACCCT GAGTGAACTC 780

AACCTGTCCT GTAATAATCT GAAGAACATT CCTGTTAAGA TAGGAAACCT CCAAAGCCTG 840

CAGACGCTGT CTTTGGATGG AAACCACCTC AGCTTCCTGC CTGATGAGGT GGGCGACCTG 900

GCCCAGCTCA ACAGTCTGGG CCTGTCTTTC AACAACTTCT CCCACATCCC CACTGTGCTG 960

GAGAGGCTGG CCGCCGTGGA CAGACTCGCC ATGGCCGGAA ACAGGGTGGA GAGTCTGCAC 1020

TTGTGCGCTC TAGCGAGAAT GAGCCACCTG AAGAGCGTTG ACCTCCGATT AAATGGGCTG 1080

AAGTGGGTGA AAAATGACAG TCTGGAGGTC GTGAGTCAGG TGACGCAAAT GGACCTTCGG 1140

GACAACTGCT TGGACACGCT AGACCTGAGC TCTGTCAGTA ATCTGGAGGC TCTTCACTGC 1200

CAGCGCAACC AGCTGGGCTC CCTGGCGCTC AGCGGCTTCA CCCTGCGCAC CATTAATGTC 1260

AGCGGCAACC GCCTCACGAC TGTTAATGTC TACCCAGTCC CTAACCAGTT GACTCACATG 1320

GACCTATCAC AGAACCTGCT GGAATACCTT CCTGACTGGG TGTCCGACTG CAGAAAAATT 1380

GAGATGCTGG ATATAACGCA CAACCTTCTG TCCGAGCTTC CGTCTAGGCT GCTCAACAGC 1440

CTGAGTTTGA GAAAGCTGCT GGCGGGGAAC AATCATTTGC AGAGAGTGCC TGACCTACTT 1500

GACCACATCC CTCTGGAAGT CCTGGACCTT CAGCACAACA GGCTCGTGGA GCTTCCAGAC 1560

AGCTTGTTTT CTAAGGCCTT AAACTTAAAA TATTTAAACG TCTCAGCCAA TGCCCTGGGA 1620

AAGATTCCTC CCAGCAGCGA ATCAGAGGAG AGCCTCAGCA CCCTCCAGGA GCTCTACCTG 1680

ACGGGGAACA GTCTGACGGA GAACTGCGGC GCTCTGTTGG TTGGACATCG GAACCTGCGG 1740

GTCCTTCACA TTGCCTACAA CCAGTTGCTC TCCTTCCCTG CCAGTAAGCT GAGCAGGCTG 1800

GAGCAGCTGG AGGAGCTGAA TCTGAGTGGG AACAAGCTAA AGACCATCCC CTCCACTGTG 1860

TCCAGCTGCA AAAGGCTGCA TACACTCATA GCACACTCCA ATCACCTCAC AGTCTTCCCT 1920

GAGATCCTCA CCCTGCCCGA GATCAAGTTT GTGGATTTGA GCTGCAACGA GCTGACGGAG 1980

ATCCAGGTGC CCGACTCGCT TCCTGCCACT CTGCAGGAGC TGGATCTGAC AGGCAACAGC 2040

AGCCTGATGC TGGAACACAA CACTCTCAAC CTCTTCAGCA ACATCGCCAC CCTGAAACTA 2100

GACCAGAAAT CAGCTGCGAC AGCAGCAGAC GTGCTGAGTG CATCCACCCC ATGGAGCCAT 2160

GGCTATTCTG AGATGAGCGG CCACAGAAAC AAGCTGTGTG TGTCTGTCTT GGCTGTTGAC 2220

CATTTTGGAG ACGGCGCGGA AGCGTGCTAC GGCGTCTTTG ACGGAGACCG CAACGAGGAA 2280

GTGCCTCGGC TGCTCCAGTG CACCATGGGA GACGTCCTGT GTGAGGAGCT GCAGCACTCC 2340

GGCGTCGACA GCGTGTACAT GTGCAACACC TTTCTCACCT CACACAGAAA ACTGGGCATG 2400

GCCGGTCAGA AGCTCGGGGC TTCGGCCCTG CTGTGTTATC TTCACCGTGA GCAGTCAGAC 2460

TCCGGAGCCA ACTTCAGCCT TACCGTTGCC AACGTGGGCG CCTGCCAGGC AGTGTTGTGC 2520

AGGGACGGCC GACCCGTACC TCTGTCCAAG GTTTACAGTT TGGAGAACAG CACGGAGGAG 2580

ATGGAGAGGG TTAAGCTCAG TAAAGCCATC ATTACGGAGG ATAACAAAGT GAGCGGGGTG 2640

ACATGCTGCT CCCGCCTGCT GGGATGCTCT TATCTGTCTC CCTGGGTGCT TCCGAAGCCC 2700

TGGGTGCACA CCGAGCATCT CCGTCCCCAG GATGAGTTCT TGATCATGGG GAACCGAGCC 2760

CTGTTCGAAC GAGTGTCTCA CCAGGAGGCC GTCCGCACCG TTCAGGCCGT GCAGGACCCT 2820

CGTGCCGCTG CCAAGAAGCT GTGTACCCTT GCCCAGAGCT ACGGCTGCAA GGACAACATC 2880

CAGGCTCTGG TGGTGTCCTT GCACATCAGT GAGGACGGCT GCACCTGCGA GCCGCCCTTC 2940

TCCGTCCCTG ACCCACGCTG TCCTCCTCCA GCAAGCGTGC CCGTCTCGGC GGCCTCCGCT 3000

TCGACCTCGG CCGACGCGGC CACCCTCTCG TCCAGCAGCG GCGTTGTCTC CGAGTTCAGC 3060

AGCGAAACCT CCGCCTCGGA GGTGGGCAGC GAAGCGGGAT CCACCGCCTC GGATGAGCAC 3120

TCGGGCCGCC CAGAGAGACG CTGCAGCCTG CACCCTGCCC CCACCCTGTG TGGGATCATG 3180

ATCCCGGGCT CGGCGGGGGC CGGGCCACAC CAGGGTCTCT TCCAGAGACA GCCGTCCTCT 3240

GCCACTTTCT CCAGCAACCA GTCCGACAAC GGCCTGGACA GCGACGACGA GGCTCCTCTG 3300

GAGGGCGTCA TCTCCAACGG CAGCAGGTTG GAAGTTGAAG TCGACATTCA CTGCTGCGCC 3360

TTCCAGCTTC GATCCGAATG CCCCAAAGAC CTGAAACTGG AAACACAAGG CTGCGATTAT 3420

GGCTGCTTGA TGGCCGTGTG CGGGAGGGAG ATTGCGGACC TAAAAAAATC TCCCTCCACA 3480

TTCAGTCTGT TTGGGAAAAA GCTTTCCAAC GGCTCCGTGG TCGCCCCTGA GGATAGTCAT 3540

AATATTATTG AGGTGGCTCT GGAGGCTCCC AAGAAGAAGT CCGGATACTT CACTGCCCCG 3600

GCTCAGCCGG ACCCCGAGGA CCAGCTGGTC GTGCCGCCGA GCCTGGAGCA GGAAGTTAGG 3660

GAGCAGCTGC GG 3672

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++++g rn+++ +v ++++f++  e+      +gv+DG++++ev + +++++ ++l

Q: 719   SHGYSEMSGHRNKLCVSVLAVDHFGDGAEA-----CYGVFDGDRNEEVPRLLQCTMGDVL  773

         789***********************8764.....8************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          eel+    ++   + ++ ++Fl+ +++l       ++ +k G++a+++++  +

Q: 774   CEELQ----HSGVDSVYMCNTFLTSHRKL------GMAGQKLGASALLCYLHREqsdsga  823

         ***99....6677778899**********......89**************988889999

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcr+g +v+ls+ ++ +++ +E+eR++  ++ +++++  +v Gv+

Q: 824   nfSLTVANVGACQAVLCRDGRPVPLSKVYSLENStEEMERVKLSKAIITEDN--KVSGVT  881

         9******************************99879*********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         ++sR lG+ yl+p+v p+P v+   l+++defli++   l++ vs +eav+ v+ v +

Q: 882   CCSRLLGCSYLSPWVLPKPWVHTEHLRPQDEFLIMGNRALFERVSHQEAVRTVQAVQD--  939

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           +++aakkL++la+++g+kdn++a+vv

Q: 940   --PRAAAKKLCTLAQSYGCKDNIQALVV  965

         ..**********************9997

Domain Sequence
(FASTA)

SHGYSEMSGH RNKLCVSVLA VDHFGDGAEA CYGVFDGDRN EEVPRLLQCT MGDVLCEELQ 60

HSGVDSVYMC NTFLTSHRKL GMAGQKLGAS ALLCYLHREQ SDSGANFSLT VANVGACQAV 120

LCRDGRPVPL SKVYSLENST EEMERVKLSK AIITEDNKVS GVTCCSRLLG CSYLSPWVLP 180

KPWVHTEHLR PQDEFLIMGN RALFERVSHQ EAVRTVQAVQ DPRAAAKKLC TLAQSYGCKD 240

NIQALVV 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>