EKS-TEN-00288

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00288

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	323.1	1.6E-96	158	408	251

Status

Unreviewed

Ensembl Protein

ENSTNIP00000012420

UniProt Accession

H3CVY6;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP2K5

Gene Synonyms/Alias

MAP2K5;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000009547	ENSTNIP00000012420	ENSTNIT00000012611

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

436

Protein Sequence
(FASTA)

SLWEMDAVPI VIRIKTPTGD MDSSVDCPSL LNFNDLLVAI RDVMPEATVT AFEYEDEVGD 60

RITVRSDEEL KAMLSYYCNT MNEQRMNGLL PDPLQIFPRA GKTPGIRNIH GLKVNTRPNP 120

ECNALPEPMS NNSLKKSSAE LKRILTNGQI NAQDIYYQEQ LGHGNGGAVY KAYHVLTRRV 180

FAVKVIPLDI TVELQKQIMS ELEILYKCDS PYIITFFSAF FVENRISICT EFMDGGSLDV 240

YKKIPEHVLG RIAVAVVKGL TYLWSLKILH RDVKPSNMLV NTRGQVKLCD FGVSTQLVNS 300

IAKTYVGTNA YMAPERISGE QYGIHADVWS VGISFMELAL GMFPYPQIQK NQGSLMPLQL 360

LQCIVDEDPP VLPVGQFSDK FIHFITQCMR RQPKERPAPN NLMDHSFIVQ YNDGNAEVVS 420

MWVCRCLEER RAQGPA 436

Nucleotide Sequence
(FASTA)

AGCCTGTGGG AAATGGACGC CGTGCCAATC GTGATTCGTA TCAAAACGCC GACAGGAGAC 60

ATGGATTCGT CCGTAGACTG TCCATCTCTT CTGAACTTCA ACGATTTGCT GGTCGCTATT 120

CGAGATGTCA TGCCCGAAGC CACCGTGACG GCCTTTGAGT ATGAAGATGA GGTGGGAGAC 180

AGAATCACTG TAAGGAGCGA TGAAGAGCTG AAAGCCATGT TGTCCTATTA CTGCAACACG 240

ATGAATGAGC AGCGCATGAA CGGACTGCTT CCAGACCCTC TGCAGATTTT TCCACGAGCC 300

GGCAAGACTC CAGGGATCCG GAACATACAT GGCCTGAAGG TGAATACAAG GCCTAACCCA 360

GAGTGTAATG CTCTTCCAGA GCCCATGAGC AACAACAGTT TAAAGAAATC GTCGGCCGAA 420

CTGAAGAGGA TCCTTACAAA TGGACAAATA AACGCACAGG ATATCTACTA CCAAGAGCAG 480

CTCGGTCACG GGAATGGAGG CGCCGTTTAC AAAGCATACC ATGTTCTTAC TAGGCGGGTT 540

TTCGCAGTCA AGGTTATTCC CCTGGATATC ACAGTGGAAT TACAGAAGCA GATTATGTCT 600

GAATTAGAAA TCCTCTACAA GTGTGATTCG CCGTACATCA TCACTTTTTT CAGTGCCTTT 660

TTTGTAGAGA ACAGGATATC GATATGCACA GAATTTATGG ATGGTGGGTC TCTGGATGTG 720

TACAAAAAAA TTCCAGAGCA CGTACTGGGG AGAATTGCAG TGGCAGTGGT CAAAGGCCTG 780

ACGTATTTGT GGAGCCTGAA AATACTTCAT CGAGACGTCA AGCCATCCAA TATGCTGGTG 840

AACACCCGGG GACAAGTCAA GCTTTGTGAC TTTGGTGTCA GCACGCAGTT GGTAAATTCC 900

ATTGCCAAAA CATACGTGGG GACAAATGCA TACATGGCGC CTGAGAGGAT ATCAGGAGAG 960

CAGTATGGCA TCCACGCAGA TGTCTGGAGC GTGGGGATCT CTTTCATGGA GTTGGCCCTA 1020

GGTATGTTCC CTTATCCACA GATTCAGAAA AACCAAGGAT CTTTAATGCC TCTCCAGTTA 1080

CTGCAATGCA TCGTTGATGA GGATCCTCCC GTGCTCCCGG TCGGACAGTT CAGCGACAAG 1140

TTCATTCACT TCATCACTCA GTGTATGCGG CGGCAACCCA AAGAGAGACC TGCCCCAAAT 1200

AACCTCATGG ACCATTCCTT CATCGTGCAG TACAACGACG GTAACGCCGA GGTGGTGTCC 1260

ATGTGGGTTT GCCGCTGTCT GGAGGAGAGA CGAGCTCAGG GACCTGCCTG A 1311

Domain Profile

S: 4     leelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyivkf  63

          e+lG+Gngg+V+k+ h  + +++avK i l+i+ e qkqi++ele+l k+ +spyi++f

Q: 158   QEQLGHGNGGAVYKAYHVLTRRVFAVKVIPLDITVELQKQIMSELEILYKC-DSPYIITF  216

         689************************************************.********

S: 64    yGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylkeklk  123

         + af+ e+++sic+e+mdg+sld v+kk       ipe+vlg+iavavvk+l+yl+ +lk

Q: 217   FSAFFVENRISICTEFMDGGSLD-VYKK-------IPEHVLGRIAVAVVKGLTYLW-SLK  267

         ***********************.6886.......9********************.78*

S: 124   iiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksavGtksYmaPEriegkkkYsvks  183

         i+HRDvKPsN+Lvn++G+vKlCDFGvs+qlv+siAk++vGt++YmaPEri+g ++Y +++

Q: 268   ILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISG-EQYGIHA  326

         ****************************************************.*******

S: 184   dvWslGltlvelatgrypyeklke......ilellkaivneeppklpeeefseefqefvs  237

         dvWs+G++++ela g +py++ ++      +l+ll++iv+e+pp+lp  +fs++f++f++

Q: 327   DVWSVGISFMELALGMFPYPQIQKnqgslmPLQLLQCIVDEDPPVLPVGQFSDKFIHFIT  386

         **********************9999**********************************

S: 238   kClkkdekeRpklkellkhafi  259

         +C+++++keRp  ++l++h+fi

Q: 387   QCMRRQPKERPAPNNLMDHSFI  408

         ********************97

Domain Sequence
(FASTA)

QEQLGHGNGG AVYKAYHVLT RRVFAVKVIP LDITVELQKQ IMSELEILYK CDSPYIITFF 60

SAFFVENRIS ICTEFMDGGS LDVYKKIPEH VLGRIAVAVV KGLTYLWSLK ILHRDVKPSN 120

MLVNTRGQVK LCDFGVSTQL VNSIAKTYVG TNAYMAPERI SGEQYGIHAD VWSVGISFME 180

LALGMFPYPQ IQKNQGSLMP LQLLQCIVDE DPPVLPVGQF SDKFIHFITQ CMRRQPKERP 240

APNNLMDHSF I 251

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>