EPS-TEN-00071

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-TEN-00071

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	242.7	3.4E-72	192	366	175

Status

Unreviewed

Ensembl Protein

ENSTNIP00000012851

UniProt Accession

H3CX66;

Protein Name

Protein Synonyms/Alias

Gene Name

TPTE

Gene Synonyms/Alias

TPTE;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000009958	ENSTNIP00000012851	ENSTNIT00000013043

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

517

Protein Sequence
(FASTA)

MSSVYFSPGS DSVPVSNVAK MEDAEVKIDD GKEDHVVPDT LYHNVRKKIT PVVMSFGFRV 60

FGVALILVDF VLVIVDISLY DRSREVGDAL EAVSLLISFF FLADVLLRVY VEGFQVYFSS 120

RLNIVDACVV AVTLVVTMIY TFSDLSGASL IPRAVSFLRF LRIIILVRVF RLASQKKELE 180

KVTRRMVSEN KRRYQKDGFD LDLTYVTDRV IAMSFPSSGK QSFYRNPIKE VARFLDTKHE 240

GHYKVYNLCS EKGYDPQFFH YRVERVFIDD HNVPSLEDML KYTASVREWM TAHPENIIAI 300

HCKGGKGRTG TMICTWLIDS DQFESAQDSL EYFGERRTDK SRSSKFQGVE TPSQSRYVGY 360

YEIMKNTFDR QLPPPKRLGI KSIRIHSIAV NEGVGKGDGS DLKIKIISKK ELIFQCVCTK 420

QENCTVRKVF PDVGSNAAVI SLHSGPVVEG DVKVMFESSA GLPKGYEDVP FYFWFNTSFI 480

ENNKLFLPRE ELDNPHKPKT WDLYKEDFGV TVFFSEP 517

Nucleotide Sequence
(FASTA)

ATGTCCTCTG TGTATTTCAG TCCAGGCTCG GATTCTGTGC CTGTTAGTAA CGTTGCAAAG 60

ATGGAGGATG CTGAAGTGAA GATTGATGAC GGGAAGGAGG ACCACGTGGT CCCAGACACC 120

TTGTACCACA ACGTGCGGAA GAAGATCACG CCCGTGGTCA TGTCTTTTGG GTTTCGGGTG 180

TTTGGCGTGG CGCTGATCCT GGTGGACTTT GTGCTGGTGA TCGTGGACAT CTCCCTGTAC 240

GACCGGAGCA GAGAGGTGGG GGATGCCTTA GAGGCCGTCT CCCTCCTCAT CTCCTTCTTC 300

TTCCTCGCCG ATGTCCTCCT GCGGGTCTAT GTGGAGGGGT TCCAGGTGTA CTTCAGCTCC 360

AGGCTGAACA TTGTGGATGC CTGTGTCGTC GCAGTCACAC TGGTGGTCAC CATGATTTAC 420

ACCTTCAGCG ACTTGTCAGG AGCCAGCCTC ATACCCAGGG CAGTCTCGTT CCTTCGCTTC 480

CTGAGGATAA TAATCCTGGT GAGGGTTTTC AGGCTGGCGT CTCAGAAGAA AGAACTGGAG 540

AAGGTCACCA GGAGGATGGT TTCTGAGAAC AAGCGGCGTT ATCAGAAGGA CGGGTTTGAC 600

CTTGACCTCA CCTATGTCAC AGATCGAGTC ATCGCTATGT CATTTCCATC CTCTGGGAAA 660

CAGTCGTTCT ACAGGAATCC TATCAAGGAG GTGGCAAGGT TCCTGGACAC AAAACACGAG 720

GGACACTATA AAGTTTACAA TCTGTGCAGT GAGAAAGGCT ACGACCCCCA GTTCTTCCAC 780

TACAGGGTTG AACGGGTGTT CATCGACGAC CACAACGTGC CCTCGTTGGA GGACATGCTG 840

AAATACACGG CGAGCGTGAG GGAGTGGATG ACCGCCCATC CTGAAAACAT CATCGCTATA 900

CACTGCAAAG GAGGGAAAGG GCGCACAGGC ACCATGATCT GCACCTGGCT TATTGACAGT 960

GACCAGTTTG AGAGCGCACA GGACAGCCTG GAATACTTTG GCGAGAGGAG GACAGATAAG 1020

AGCCGCAGCT CCAAGTTTCA GGGAGTGGAG ACCCCGTCTC AGAGTCGGTA TGTGGGGTAC 1080

TACGAGATTA TGAAGAACAC GTTCGACAGA CAGCTGCCCC CGCCGAAAAG ACTGGGCATC 1140

AAAAGCATCC GTATTCACTC CATCGCAGTC AATGAAGGTG TGGGCAAAGG TGACGGCAGC 1200

GACCTGAAGA TTAAGATCAT TTCAAAGAAA GAGCTGATAT TTCAGTGTGT GTGTACCAAA 1260

CAGGAGAACT GCACGGTGAG AAAGGTCTTC CCCGATGTGG GCAGCAACGC AGCCGTCATC 1320

AGCCTGCACA GCGGGCCTGT GGTTGAAGGG GACGTGAAGG TCATGTTTGA ATCGAGTGCT 1380

GGTCTGCCGA AAGGCTACGA GGATGTGCCC TTCTACTTCT GGTTCAACAC CTCCTTCATT 1440

GAGAACAACA AGCTGTTTCT ACCTCGAGAA GAGCTGGACA ACCCTCACAA GCCGAAGACC 1500

TGGGACCTCT ACAAGGAGGA CTTTGGAGTG ACCGTGTTCT TTTCAGAGCC ATAA 1554

Domain Profile

S: 1     rrltedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcse  60

         rr+++dgfdldltyvt+r+ia+sfP+++++++yrn+++ev+r+ld kh+++yk+ynlcse

Q: 192   RRYQKDGFDLDLTYVTDRVIAMSFPSSGKQSFYRNPIKEVARFLDTKHEGHYKVYNLCSE  251

         79**********************************************************

S: 61    rrydltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGv  120

         + yd++ ++ +v+++ i+d+n+P+le +  ++  + eW+++ +en++++hckggkgr+G+

Q: 252   KGYDPQFFHYRVERVFIDDHNVPSLEDMLKYTASVREWMTAHPENIIAIHCKGGKGRTGT  311

         ************************************************************

S: 121   ivcayllaseisakadealdtfgerr...tredkvagvkqPsqrryvsyfsqllk  172

         ++c++l+ s+ + +a+++l++fgerr    r+ k++gv++Psq ryv y+  +++

Q: 312   MICTWLIDSDQFESAQDSLEYFGERRtdkSRSSKFQGVETPSQSRYVGYYEIMKN  366

         **************************6666899*****************98775

Domain Sequence
(FASTA)

RRYQKDGFDL DLTYVTDRVI AMSFPSSGKQ SFYRNPIKEV ARFLDTKHEG HYKVYNLCSE 60

KGYDPQFFHY RVERVFIDDH NVPSLEDMLK YTASVREWMT AHPENIIAIH CKGGKGRTGT 120

MICTWLIDSD QFESAQDSLE YFGERRTDKS RSSKFQGVET PSQSRYVGYY EIMKN 175

Keyword

Complete proteome; Ion transport; Ionic channel; Membrane; Reference proteome; Transmembrane; Transport.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016021	; C:integral to membrane
GO:0005216	; F:ion channel activity
GO:0016314	; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation
GO:0046856	; P:phosphatidylinositol dephosphorylation

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR005821	; Ion_trans_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR014020	; Tensin_phosphatase_C2-dom.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782	; DSPc; 1.
PF00520	; Ion_trans; 1.
PF10409	; PTEN_C2; 1.

SMARTs

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS00383	; TYR_PHOSPHATASE_1; 1.

Prints

Created Date

20-Feb-2013