EKS-TEN-00092

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00092

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	347.6	5.5E-104	54	339	286

Status

Unreviewed

Ensembl Protein

ENSTNIP00000013536

UniProt Accession

H3CZ51;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK15

Gene Synonyms/Alias

CDK15;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000010623	ENSTNIP00000013536	ENSTNIT00000013730

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

388

Protein Sequence
(FASTA)

LSQPDPPRPP QPHWFHTLQV RQRRGRRGRS NSDPVGEEAF SWRPALGFGA AHSYLSLEKL 60

GQGAYASVYK GISRINGQLV ALKVIRMRTE EGVPFTAIRE ASLLKRLKHA NVVLLHDIVH 120

TSQTLTLVFE YVQTDLGQYL SQHPGGLRPH NVQIFLFQLL RALSYIHSRR VLHRDLKPQN 180

LLVSHRGELK LADFGLARSR SVPSQTFSSE VVTLWYRPPD VLLGSTDYST ALDIWGAGCV 240

FVEMLQGAPA FPGEAAELQQ LQTICKVLGV PSEENWPGIS QLPNYQPDSF VESERKPLGT 300

VWKRLKQLPG RTEELVQEML KMPPAGRISA QQALRHPYFS TLPPLIMHLK DTVSIFKVPG 360

VHLEPEAGDV SNPGRRLRWT LLPAAKFW 388

Nucleotide Sequence
(FASTA)

CTGTCCCAGC CGGACCCGCC CCGCCCCCCC CAGCCTCACT GGTTCCACAC GCTGCAGGTC 60

CGCCAGCGGC GAGGGCGGCG TGGGCGCAGC AACAGCGACC CTGTGGGCGA GGAGGCCTTC 120

TCCTGGAGAC CGGCGCTGGG CTTCGGCGCC GCCCACTCCT ACCTGAGCCT GGAGAAGCTG 180

GGCCAAGGAG CCTACGCCTC CGTCTACAAG GGCATCAGCA GGATCAACGG ACAGTTGGTG 240

GCGCTGAAGG TGATCCGGAT GAGGACGGAG GAGGGCGTCC CCTTCACCGC CATCAGAGAA 300

GCTTCTCTGC TCAAACGCCT GAAACACGCC AACGTGGTCC TCCTGCACGA CATCGTCCAC 360

ACCAGCCAGA CTCTCACCTT GGTCTTCGAA TACGTGCAGA CGGACCTGGG CCAGTACCTG 420

AGCCAGCACC CCGGCGGACT GCGGCCCCAC AACGTCCAGA TCTTCCTGTT CCAGCTGCTG 480

CGAGCGCTGA GCTACATCCA CAGCCGGAGG GTCCTCCACC GGGACCTGAA GCCCCAGAAC 540

CTGCTCGTCA GCCACCGGGG GGAGCTGAAG CTGGCTGACT TTGGTCTGGC CCGGTCCAGG 600

TCCGTCCCCA GTCAGACCTT CTCCTCGGAG GTGGTGACGC TGTGGTACCG CCCCCCCGAT 660

GTCCTGCTGG GATCCACTGA TTACTCCACG GCTCTGGACA TCTGGGGAGC CGGGTGCGTC 720

TTTGTTGAGA TGCTGCAGGG GGCGCCGGCG TTTCCAGGAG AGGCTGCTGA GCTCCAGCAG 780

CTGCAGACCA TCTGCAAGGT GCTGGGCGTG CCCTCGGAGG AGAACTGGCC TGGGATCAGC 840

CAGCTCCCCA ACTATCAGCC AGACTCGTTC GTGGAGTCGG AGCGGAAGCC GCTGGGGACG 900

GTCTGGAAAA GGTTGAAGCA GCTGCCCGGC CGGACCGAAG AGCTGGTCCA GGAGATGCTG 960

AAGATGCCCC CTGCTGGCAG GATCTCGGCG CAGCAGGCGC TGCGACACCC GTACTTCAGC 1020

ACGCTCCCTC CTCTCATCAT GCACCTCAAA GACACCGTGT CCATTTTTAA GGTTCCTGGG 1080

GTCCACCTGG AGCCGGAGGC CGGAGACGTC TCCAACCCTG GACGGAGGCT GAGATGGACG 1140

CTGCTGCCTG CTGCCAAATT CTGGTGA 1167

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y +lek+g+G+y+ vyk+ ++ +g++vAlK ir+ +e egvp+ta+rE sllk+lkh+n+

Q: 54    YLSLEKLGQGAYASVYKGISRINGQLVALKVIRMRTE-EGVPFTAIREASLLKRLKHANV  112

         6789*******************************99.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v L+++v+ ++++l+Lvfe++++dL ++l++++  +l++++v+ +l+qll++l+y+Hs++

Q: 113   VLLHDIVH-TSQTLTLVFEYVQTDLGQYLSQHPG-GLRPHNVQIFLFQLLRALSYIHSRR  170

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlL+s++g+lklaDfGlar+ s+p++t+++evvTlwYr+P++Llg+++Yst

Q: 171   VLHRDLKPQNLLVSHRGELKLADFGLARSRSVPSQTFSSEVVTLWYRPPDVLLGSTDYST  230

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgks.eidqlerifkllgtpsekvwpevsklpeyk.ksf  238

         a+DiW++gc+++e+l+  p f+g+  e +ql++i k+lg pse++wp++s+lp+y+  sf

Q: 231   ALDIWGAGCVFVEMLQGAPAFPGEAaELQQLQTICKVLGVPSEENWPGISQLPNYQpDSF  290

         ***********************86379****************************8899

S: 239   pkkkkkklkekvkklk...ekaldllekllaldpkkRisakealqhkyf  284

          ++++k l +++k+lk    ++ +l++++l++ p+ Risa++al+h+yf

Q: 291   VESERKPLGTVWKRLKqlpGRTEELVQEMLKMPPAGRISAQQALRHPYF  339

         99999999999988883324689*************************9

Domain Sequence
(FASTA)

YLSLEKLGQG AYASVYKGIS RINGQLVALK VIRMRTEEGV PFTAIREASL LKRLKHANVV 60

LLHDIVHTSQ TLTLVFEYVQ TDLGQYLSQH PGGLRPHNVQ IFLFQLLRAL SYIHSRRVLH 120

RDLKPQNLLV SHRGELKLAD FGLARSRSVP SQTFSSEVVT LWYRPPDVLL GSTDYSTALD 180

IWGAGCVFVE MLQGAPAFPG EAAELQQLQT ICKVLGVPSE ENWPGISQLP NYQPDSFVES 240

ERKPLGTVWK RLKQLPGRTE ELVQEMLKMP PAGRISAQQA LRHPYF 286

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013