EKS-TEN-00485

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00485

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/MLK	276.9	1.8E-82	570	819	250

Status

Unreviewed

Ensembl Protein

ENSTNIP00000013614

UniProt Accession

H3CZC9;

Protein Name

Protein Synonyms/Alias

Gene Name

FPGT-TNNI3K

Gene Synonyms/Alias

FPGT-TNNI3K;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000010698	ENSTNIP00000013614	ENSTNIT00000013808

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

942

Protein Sequence
(FASTA)

CAKPASDPEE YATKLRAATR EKLKKFNSLR GRQVQPGEFW DVVVLTAVDG DQRGAYELQM 60

AEKVKRKELP RGPHYKIFSD PPGCKIGNGG STLYALQQLS DAYGEALSSL RVLLIHADEW 120

KKKVGESYAV IIERLDDDLQ LKDSELADLR LAFSSDEAFQ KVNLSYRTEK GLSLLHLCCV 180

CEGSKAHIRT LILKGLRPSR LSRNGFTALH LAAYKDNAEL VTALLHGGSD VQQVGYGALT 240

ALHVATLAGH HEATDILLQH GANVNVQDAV FFTPLHIASC YGHEQVAKLL LKFGADENVS 300

GEVGDRPLHL AAAKGFLSIV KLLVEEGSKA KVNAKDNEDH IPLHFSARFG HHEVVRFLLQ 360

GNFDVQPHAV NIYGDTPLHL ACYNGKFESV KEIVQLSGTD GLSKENIFSE TVLHRQCVHY 420

GKDLEMVKFL LSQNAMSINH QGRDGHTALH SACFHGHIRL VQFLLDNGAD MNLVACDPSR 480

SSGEKDEQTC LMWAYEKGHD AIVTLLKHYK RPDDSPCNEY SQPGGASDGS YVSVPSPLGK 540

IKSMTKEKAE VLLLRVSLPS HFHLQMSELE FNEIIGSGSF GRVYRGKCRN KIVAIKRYRA 600

NTYCSKSDVD MFCREVSILC CLNHPCIIQF VGACLDDPSQ FAIVTQYVSG GSLFSLLHEQ 660

KRLIDMQSKL IIAIDVAKGM EYLHNLTQPI IHRDLNSHNI LLYEDGHAGL ADFGESRFLQ 720

SVDEDNMTKQ PGNLRWMAPE VFTQCTRYSV KADMFSYALC LWELFTGEIP FAHLKPAAAA 780

ADMAYHHIRP PIGYSIPKPI STLLMRGWYA CPERREEFGE KEDVYNENEC EKQLMAPASS 840

NSSGSLSPSS SSDCLLGRGG PGRSHVAALR SRFELEYALN TRAYAYWSQS ERRRASGGLS 900

LEEVRKNMQR SPIDRNGYVS DPMSTMRCSS SFSSGGSFED SN 942

Nucleotide Sequence
(FASTA)

TGCGCAAAAC CCGCCTCAGA CCCGGAAGAA TATGCGACAA AGTTACGGGC TGCGACAAGA 60

GAAAAACTCA AAAAGTTTAA CTCTTTGCGA GGTCGACAGG TGCAACCTGG TGAGTTTTGG 120

GACGTGGTGG TTCTGACAGC AGTAGACGGG GACCAGCGAG GAGCCTACGA GCTGCAGATG 180

GCAGAGAAAG TGAAGAGGAA GGAGCTTCCA CGGGGCCCTC ACTACAAGAT CTTCTCAGAT 240

CCACCTGGGT GTAAAATCGG AAACGGCGGC TCGACCCTGT ACGCGCTGCA GCAGCTGAGT 300

GACGCCTACG GGGAGGCTCT GAGCAGCCTG AGAGTCCTTC TCATTCATGC AGATGAGTGG 360

AAGAAGAAGG TGGGGGAGTC GTACGCCGTG ATCATTGAGA GGCTGGACGA TGACCTCCAG 420

CTCAAAGACA GCGAGCTTGC GGACCTCAGA CTTGCTTTCA GTTCTGACGA GGCTTTCCAG 480

AAAGTGAATC TGAGCTACAG GACAGAGAAG GGGCTGTCGC TGCTGCACCT CTGCTGCGTG 540

TGTGAAGGCA GCAAGGCCCA TATCCGTACT TTAATTCTGA AAGGCCTCCG CCCGTCCCGT 600

CTGTCCAGGA ATGGTTTCAC CGCCCTTCAT CTTGCTGCCT ACAAGGATAA CGCTGAGCTG 660

GTGACCGCAC TTCTGCACGG GGGGTCAGAC GTGCAGCAGG TGGGCTACGG CGCCCTGACC 720

GCCCTGCATG TGGCCACACT GGCGGGTCAT CACGAGGCAA CAGATATCCT CCTGCAGCAC 780

GGAGCTAACG TGAACGTCCA GGATGCTGTG TTTTTCACCC CGCTGCATAT CGCCTCTTGT 840

TACGGCCATG AGCAGGTTGC AAAGCTGCTG CTGAAGTTTG GGGCTGACGA GAACGTGAGT 900

GGCGAGGTAG GCGATCGTCC TCTTCACCTG GCCGCGGCCA AAGGCTTCCT GAGCATCGTC 960

AAACTGCTGG TGGAGGAGGG AAGCAAAGCC AAAGTAAACG CCAAGGACAA CGAGGATCAC 1020

ATTCCTCTCC ACTTCAGCGC CCGCTTCGGT CATCACGAGG TGGTCCGCTT CCTCCTGCAG 1080

GGCAACTTTG ACGTGCAGCC ACACGCTGTC AACATCTATG GAGACACACC GTTACACTTG 1140

GCCTGTTATA ACGGCAAATT CGAGTCAGTG AAGGAGATCG TGCAGCTCTC TGGTACAGAC 1200

GGCCTCTCAA AGGAGAACAT ATTCAGTGAG ACAGTGCTTC ACAGACAGTG CGTGCACTAC 1260

GGAAAAGACC TGGAGATGGT CAAGTTCCTG TTGAGCCAGA ACGCTATGAG CATCAACCAC 1320

CAGGGCAGAG ATGGACACAC AGCTCTGCAC AGCGCCTGTT TTCACGGACA CATCCGCCTG 1380

GTGCAGTTCC TGCTGGATAA CGGAGCAGAC ATGAACCTGG TCGCCTGTGA CCCCAGCAGG 1440

TCCAGTGGGG AGAAAGACGA GCAGACCTGC CTGATGTGGG CTTATGAAAA AGGTCACGAC 1500

GCTATCGTCA CCTTACTGAA ACACTACAAA CGTCCCGATG ACTCTCCCTG CAATGAGTAC 1560

TCCCAGCCAG GAGGGGCCTC AGATGGTTCC TATGTTTCCG TCCCATCTCC TCTGGGAAAG 1620

ATCAAAAGCA TGACAAAAGA GAAAGCCGAA GTGCTCCTCC TCAGGGTCAG CCTTCCGTCT 1680

CATTTCCATC TTCAGATGTC CGAGCTGGAG TTTAATGAGA TTATCGGTTC AGGCTCCTTC 1740

GGCCGAGTCT ACCGAGGCAA GTGCCGAAAT AAAATAGTTG CCATCAAACG GTACCGAGCC 1800

AACACCTACT GCTCCAAGTC CGACGTTGAT ATGTTCTGCA GAGAGGTCTC CATCCTGTGT 1860

TGCCTCAATC ACCCCTGCAT CATCCAGTTT GTGGGGGCCT GTTTGGATGA CCCCAGCCAG 1920

TTTGCCATCG TGACCCAGTA TGTCTCTGGA GGCTCGTTGT TCTCTCTGCT ACATGAACAG 1980

AAGAGGCTCA TCGACATGCA GTCCAAGCTC ATCATTGCCA TTGACGTGGC CAAGGGTATG 2040

GAGTACCTGC ACAATCTCAC CCAGCCCATC ATCCACAGGG ACCTCAACAG CCACAATATT 2100

CTGCTGTATG AAGACGGACA CGCAGGGTTG GCTGATTTTG GGGAATCTAG ATTTCTACAG 2160

TCCGTGGACG AGGACAACAT GACCAAGCAG CCAGGGAACC TCCGCTGGAT GGCTCCTGAA 2220

GTGTTTACGC AGTGTACCCG TTACTCTGTG AAGGCAGACA TGTTCAGCTA TGCCCTCTGC 2280

CTCTGGGAGC TGTTCACTGG AGAGATTCCC TTTGCTCACT TGAAACCTGC TGCTGCAGCA 2340

GCAGACATGG CCTACCACCA CATCCGGCCT CCAATTGGCT ATTCCATCCC CAAACCCATC 2400

TCCACGCTCC TGATGAGAGG CTGGTACGCC TGCCCAGAGA GAAGGGAGGA ATTCGGTGAG 2460

AAAGAGGATG TGTACAATGA GAATGAATGT GAAAAGCAGC TGATGGCGCC AGCCTCCAGC 2520

AACAGCAGCG GCTCCCTGTC TCCCTCCTCC TCCTCCGACT GCCTGCTCGG CCGCGGTGGG 2580

CCCGGGCGGA GTCATGTGGC CGCCTTGCGC TCTCGTTTTG AGCTGGAGTA CGCCCTCAAC 2640

ACTCGGGCCT ACGCGTACTG GTCCCAGAGC GAGCGGCGTC GTGCTTCCGG GGGGCTTTCA 2700

CTGGAGGAAG TCCGGAAGAA CATGCAACGT TCTCCGATTG ATCGCAACGG CTACGTGTCT 2760

GATCCCATGA GCACAATGAG GTGTTCTTCG TCTTTCAGCA GCGGTGGCAG CTTTGAGGAC 2820

AGTAACTAA 2829

Domain Profile

S: 2     eleeligsgafgkvykakwrkkevavKklreeaee.kekleklereakllsklshpniie  60

         e++e+igsg+fg vy++k+r+k va+K++r+++++ k+++++++re+++l+ l+hp+ii+

Q: 570   EFNEIIGSGSFGRVYRGKCRNKIVAIKRYRANTYCsKSDVDMFCREVSILCCLNHPCIIQ  629

         789****************************99998999*********************

S: 61    llGvcleepn.lllvmeyveggsLsnvlhekskreidlevlvswalqiArGmaYLhseap  119

         ++G+cl++p+ +++v++yv+ggsL+++lhe +kr id++  + +a+++A+Gm+YLh+ ++

Q: 630   FVGACLDDPSqFAIVTQYVSGGSLFSLLHE-QKRLIDMQSKLIIAIDVAKGMEYLHNLTQ  688

         **********99******************.99*************************66

S: 120   kkiihrdLksknvLlseekktlkicdFGtarelsk..stkmsaa.gtlawmaPEvl.kee  175

          +iihrdL+s+n+Ll  e+ ++ ++dFG++r+l++  +++m+++ g+l+wmaPEv+ +++

Q: 689   -PIIHRDLNSHNILL-YEDGHAGLADFGESRFLQSvdEDNMTKQpGNLRWMAPEVFtQCT  746

         .9*************.******************99877777777***************

S: 176   kvseksDvwSygvvLWelltrevPykdlselaiaykvalkglrlpipsscpeklkkLmke  235

         ++s k+D++Sy+++LWel t+e+P+++l+++a+a+++a++++r+pi+ s+p+++++L+ +

Q: 747   RYSVKADMFSYALCLWELFTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISTLLMR  806

         ************************************************************

S: 236   cwnedpekRpsfs  248

          w ++pe+R +f

Q: 807   GWYACPERREEFG  819

         *********9986

Domain Sequence
(FASTA)

EFNEIIGSGS FGRVYRGKCR NKIVAIKRYR ANTYCSKSDV DMFCREVSIL CCLNHPCIIQ 60

FVGACLDDPS QFAIVTQYVS GGSLFSLLHE QKRLIDMQSK LIIAIDVAKG MEYLHNLTQP 120

IIHRDLNSHN ILLYEDGHAG LADFGESRFL QSVDEDNMTK QPGNLRWMAP EVFTQCTRYS 180

VKADMFSYAL CLWELFTGEI PFAHLKPAAA AADMAYHHIR PPIGYSIPKP ISTLLMRGWY 240

ACPERREEFG 250

Keyword

ANK repeat; Complete proteome; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Equus caballus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity

KEGG

InterPros

IPR002110	; Ankyrin_rpt.
IPR020683	; Ankyrin_rpt-contain_dom.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.

Pfam

PF12796	; Ank_2; 4.
PF07714	; Pkinase_Tyr; 1.

SMARTs

SM00248

; ANK; 10.

Prosites

PS50297	; ANK_REP_REGION; 1.
PS50088	; ANK_REPEAT; 7.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

PR01415

; ANKYRIN.

Created Date

20-Feb-2013