EKS-TEN-00134

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00134

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MLCK	357.7	3.8E-107	235	490	256

Status

Unreviewed

Ensembl Protein

ENSTNIP00000014650

UniProt Accession

H3D2B2;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000011699	ENSTNIP00000014650	ENSTNIT00000014850

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

605

Protein Sequence
(FASTA)

LPVNVIQFKN PPQLVQLQAG QAARVTCSFS GSPPVVSCWI RNKEQIVDGP ELWVETTDLS 60

STLVIAEVTA QHAGRYTIVV RDRRSSAQHT LTLSVIERPQ PPASCPVISL VSATSLALSW 120

SGPCYDGGSA VLGYVVEIKN PGGADSADWR KLTDQCTSTS YIVTELQAHQ EYCFRVSAYN 180

AVGISQPGPV SPLVRMEQKA IVSLFVDLDK PEKEEDPQNF TFVTIDSAHK VSDHYILQEK 240

LGMGKFGQVF KLIHKETGHV CAGKFYKGRR SKEREAARNE IELMNYLHHP KLVQCLAAYD 300

QKPEMVMVME FIAGGELFER IVDDNFEHTE PASVNYMQQI LEGVAFMHQQ NIVHLDLKPE 360

NIVCVDTTGT SIKIIDFGLA SRLDNTTPLK VMQGTPEFVA PEVINYEPVC AATDMWSIGV 420

ICYILLSGES PFQGDNDVET LALVTAAQWE FDEESFEEIT QEAKDFISSL VIKETRKRMT 480

CKQALAHPWM AAFDSGKLET KNLSKEKMKK FLARQKWKKA GKALLALKRM ALLSKSESTA 540

SPTSSGEGKT SSSGFVDSSL HHKTLEHKMQ GAPHFTQSLQ DQTVTSGSSV RLSCHLTGYP 600

DPEVV 605

Nucleotide Sequence
(FASTA)

CTGCCTGTAA ATGTAATACA GTTCAAGAAC CCCCCGCAGC TTGTCCAGCT GCAGGCGGGG 60

CAAGCTGCAC GTGTGACATG TTCCTTCAGC GGCAGCCCTC CCGTAGTCTC CTGTTGGATC 120

AGGAATAAAG AACAGATTGT TGATGGTCCG GAATTGTGGG TAGAAACCAC AGACCTGAGC 180

AGCACATTGG TGATAGCAGA GGTGACGGCG CAGCACGCAG GTCGCTACAC GATAGTAGTG 240

AGAGATCGCA GGAGCTCCGC ACAGCACACA CTTACTCTGT CTGTGATAGA AAGACCCCAA 300

CCTCCGGCCT CCTGTCCTGT CATCTCCCTG GTTTCGGCCA CGAGCCTCGC GCTGTCCTGG 360

TCCGGGCCCT GTTATGATGG TGGCAGTGCC GTTCTGGGCT ACGTGGTGGA GATAAAGAAC 420

CCAGGAGGAG CTGATTCTGC AGACTGGAGG AAGCTGACCG ATCAGTGTAC GAGCACCTCC 480

TACATAGTGA CCGAGCTGCA AGCTCACCAG GAGTACTGTT TCCGAGTGAG TGCCTACAAC 540

GCGGTGGGAA TAAGCCAGCC GGGACCAGTT TCACCGCTGG TTAGGATGGA GCAGAAAGCT 600

ATTGTGTCTT TATTTGTAGA TTTAGACAAA CCAGAGAAAG AGGAGGACCC TCAAAACTTC 660

ACCTTTGTCA CCATTGACTC CGCCCACAAA GTCAGCGACC ACTATATTTT ACAGGAAAAA 720

CTGGGAATGG GAAAGTTTGG CCAGGTATTC AAGTTAATCC ACAAGGAAAC AGGGCATGTG 780

TGTGCTGGTA AGTTTTACAA AGGTCGACGA TCCAAAGAGA GAGAGGCTGC CCGTAACGAG 840

ATAGAGCTGA TGAACTACCT CCACCACCCA AAACTGGTTC AGTGCCTGGC CGCCTATGAT 900

CAGAAACCAG AAATGGTCAT GGTTATGGAA TTTATTGCAG GCGGAGAGCT ATTTGAGCGC 960

ATTGTGGATG ACAACTTTGA GCACACCGAG CCTGCAAGTG TGAACTACAT GCAGCAGATC 1020

CTAGAGGGTG TCGCCTTCAT GCACCAGCAG AACATTGTGC ATCTGGACCT TAAACCTGAA 1080

AACATCGTGT GTGTTGACAC GACCGGCACC TCTATTAAGA TCATTGATTT CGGATTAGCA 1140

AGCAGACTAG ATAACACCAC GCCTCTTAAG GTGATGCAAG GCACTCCAGA GTTTGTTGCA 1200

CCAGAGGTGA TTAACTATGA GCCTGTGTGT GCAGCCACTG ATATGTGGAG CATCGGGGTC 1260

ATCTGTTACA TCTTACTCAG CGGTGAGTCT CCCTTCCAGG GCGACAATGA TGTAGAAACT 1320

CTGGCCTTGG TCACTGCCGC ACAGTGGGAG TTTGATGAGG AAAGCTTTGA GGAGATCACG 1380

CAGGAGGCCA AAGATTTCAT CAGTTCCTTG GTTATCAAAG AGACAAGGAA GAGAATGACC 1440

TGTAAACAGG CCCTGGCTCA TCCTTGGATG GCAGCGTTTG ACTCTGGAAA GTTGGAGACC 1500

AAAAATCTGT CAAAGGAGAA GATGAAGAAG TTTCTGGCTC GGCAAAAGTG GAAGAAAGCC 1560

GGCAAGGCTT TGTTGGCCCT GAAAAGAATG GCTCTGCTGT CTAAAAGTGA AAGCACCGCA 1620

TCTCCTACCA GCTCTGGAGA AGGTAAAACG AGTTCATCTG GCTTTGTAGA CTCTTCTTTA 1680

CACCACAAGA CCCTGGAGCA CAAGATGCAG GGGGCACCCC ACTTCACCCA GAGCCTGCAG 1740

GACCAGACCG TGACCTCAGG ATCCAGCGTA CGTCTGTCCT GTCACCTCAC GGGATACCCG 1800

GACCCGGAGG TGGTG 1815

Domain Profile

S: 1     ysikeelgkGkfgvvvkavekstgkklaakivkvrkekdkeevkkEieilnqlrHekliq  60

         y  +e+lg Gkfg+v+k + k+tg++ a+k+ k r++k++e +++Eie +n l+H+kl+q

Q: 235   YILQEKLGMGKFGQVFKLIHKETGHVCAGKFYKGRRSKEREAARNEIELMNYLHHPKLVQ  294

         56789*******************************************************

S: 61    lydafeskeeivlvlElveggelferiveedyeltEeevvlfvrqvlealeylHkkgivH  120

         + +a+++k e+v+v+E+++ggelferiv++++e tE + v++++q+le+++++H+++ivH

Q: 295   CLAAYDQKPEMVMVMEFIAGGELFERIVDDNFEHTEPASVNYMQQILEGVAFMHQQNIVH  354

         ************************************************************

S: 121   ldlkpenillqskkskqiKlidFGlarklkkkeklkvlfgtpefvaPEvvnkepvslatD  180

         ldlkpeni+++++++++iK+idFGla +l++++ lkv+ gtpefvaPEv+n+epv  atD

Q: 355   LDLKPENIVCVDTTGTSIKIIDFGLASRLDNTTPLKVMQGTPEFVAPEVINYEPVCAATD  414

         ************************************************************

S: 181   mWsvGvityvLlsGlsPFlgdndeetlenvssakydfdeeafkevseeakdFiskllvke  240

         mWs+Gvi+y+LlsG sPF gdnd etl+ v++a+++fdee+f+e+++eakdFis l++ke

Q: 415   MWSIGVICYILLSGESPFQGDNDVETLALVTAAQWEFDEESFEEITQEAKDFISSLVIKE  474

         ************************************************************

S: 241   kkkRmsaeeaLkhkwl  256

          +kRm++++aL+h+w+

Q: 475   TRKRMTCKQALAHPWM  490

         ***************7

Domain Sequence
(FASTA)

YILQEKLGMG KFGQVFKLIH KETGHVCAGK FYKGRRSKER EAARNEIELM NYLHHPKLVQ 60

CLAAYDQKPE MVMVMEFIAG GELFERIVDD NFEHTEPASV NYMQQILEGV AFMHQQNIVH 120

LDLKPENIVC VDTTGTSIKI IDFGLASRLD NTTPLKVMQG TPEFVAPEVI NYEPVCAATD 180

MWSIGVICYI LLSGESPFQG DNDVETLALV TAAQWEFDEE SFEEITQEAK DFISSLVIKE 240

TRKRMTCKQA LAHPWM 256

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Repeat; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Caenorhabditis elegans"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Gasterosteus aculeatus"; ?>Ornithorhynchus anatinus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR003961	; Fibronectin_type3.
IPR007110	; Ig-like.
IPR013783	; Ig-like_fold.
IPR013098	; Ig_I-set.
IPR003599	; Ig_sub.
IPR011009	; Kinase-like_dom.
IPR020675	; Myosin_light_ch_kinase-rel.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00041	; fn3; 1.
PF07679	; I-set; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00060	; FN3; 1.
SM00409	; IG; 1.
SM00220	; S_TKc; 1.

Prosites

PS50853	; FN3; 1.
PS50835	; IG_LIKE; 2.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013