EKS-TEN-00540

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00540

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	502.7	2.8E-151	22	279	258

Status

Unreviewed

Ensembl Protein

ENSTNIP00000014976

UniProt Accession

H3D388;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK2

Gene Synonyms/Alias

SGK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000012015	ENSTNIP00000014976	ENSTNIT00000015178

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

351

Protein Sequence
(FASTA)

SSSHDDVNLG PSANPHARPT DFDFLAVIGK GTFGKVLLAK HKTDSSFYAV KVLQKKVILK 60

KKEQKNIMAE RNVLLKSLKH PFLVRLHYSF QTAEKLYFVL DYVNGGELFF HLQRERCFSE 120

PRARFYAAEV ASAIGYLHSL NIVYRDLKPE NILLDSQGHV VLTDFGLCKE GVEPEGTTST 180

FCGTPEYLAP EVLRKEPYDR TVDWWCLGAV LYEMIYSLPP FYSRDVGVMY DGILHKPLQL 240

PPGKSDAVCS LLVGLLQKDQ HRRLGAIADF LEIKNHVFFT PINWDDLYHK RITPPYNPNV 300

RGPADTQHID PEFTREMVSS SVSQTPEFTA SASASNAFNG FSFVATEDSF L 351

Nucleotide Sequence
(FASTA)

TCTTCCTCCC ACGATGACGT TAACCTGGGA CCTTCAGCAA ACCCACATGC CCGGCCCACT 60

GACTTTGACT TCTTGGCTGT CATTGGAAAA GGCACTTTTG GAAAGGTCCT GCTCGCCAAG 120

CATAAAACAG ATAGCAGCTT CTACGCTGTC AAAGTGCTGC AGAAGAAGGT CATCCTGAAG 180

AAAAAAGAGC AAAAGAACAT CATGGCTGAG AGGAATGTGC TCCTGAAAAG CCTCAAACAC 240

CCTTTCTTGG TCCGGCTCCA TTACTCCTTT CAGACTGCAG AGAAGCTTTA CTTTGTCCTT 300

GACTATGTCA ATGGAGGAGA GCTGTTCTTT CATTTGCAAA GAGAACGGTG CTTCTCTGAG 360

CCGAGAGCGA GGTTCTACGC TGCAGAGGTG GCGAGCGCCA TCGGCTATCT TCACTCTCTC 420

AACATTGTCT ACAGAGATTT GAAGCCAGAG AATATTCTCC TGGACTCTCA GGGCCACGTG 480

GTGCTTACAG ATTTTGGCCT GTGCAAAGAA GGTGTTGAGC CAGAGGGAAC CACCTCCACA 540

TTCTGTGGGA CTCCAGAGTA TTTGGCCCCG GAGGTTCTTC GTAAGGAGCC GTATGACAGG 600

ACGGTGGACT GGTGGTGTCT GGGAGCTGTG CTCTATGAGA TGATCTACAG TCTCCCTCCG 660

TTCTACAGCC GGGACGTGGG GGTGATGTAC GACGGAATCC TCCACAAGCC GCTGCAGCTG 720

CCGCCAGGGA AGTCTGACGC CGTCTGCTCG CTCCTGGTGG GTCTCCTGCA GAAGGACCAG 780

CACAGGCGTC TCGGGGCCAT CGCCGACTTT TTAGAAATAA AGAACCATGT CTTTTTCACT 840

CCAATCAACT GGGACGACCT TTATCACAAA AGAATCACTC CTCCTTACAA CCCAAACGTT 900

AGAGGTCCAG CCGACACCCA GCACATCGAT CCAGAGTTCA CCAGAGAAAT GGTCTCCAGC 960

TCCGTGAGTC AGACCCCAGA GTTCACCGCC AGCGCCAGCG CCAGCAACGC CTTCAACGGC 1020

TTCTCCTTCG TGGCCACCGA GGACAGCTTT CTGTGA 1056

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdfl vigkg+fgkvllak+k+d  fyavkvlqkk ilkkke+k imaernvllk +khp

Q: 22    FDFLAVIGKGTFGKVLLAKHKTDSSFYAVKVLQKKVILKKKEQKNIMAERNVLLKSLKHP  81

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flv lhysfqtaeklyfvldyvnggelffhlqrer+f+eprarfyaae+asa+gylhsln

Q: 82    FLVRLHYSFQTAEKLYFVLDYVNGGELFFHLQRERCFSEPRARFYAAEVASAIGYLHSLN  141

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenillds+ghvvltdfglcke++e e ttstfcgtpeylapevlrk+pydrt

Q: 142   IVYRDLKPENILLDSQGHVVLTDFGLCKEGVEPEGTTSTFCGTPEYLAPEVLRKEPYDRT  201

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyem+y lppfysrdv  myd il+kplql+pg s a+++ll +ll+kd++

Q: 202   VDWWCLGAVLYEMIYSLPPFYSRDVGVMYDGILHKPLQLPPGKSDAVCSLLVGLLQKDQH  261

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlga +dfleiknhvff

Q: 262   RRLGAIADFLEIKNHVFF  279

         *****************9

Domain Sequence
(FASTA)

FDFLAVIGKG TFGKVLLAKH KTDSSFYAVK VLQKKVILKK KEQKNIMAER NVLLKSLKHP 60

FLVRLHYSFQ TAEKLYFVLD YVNGGELFFH LQRERCFSEP RARFYAAEVA SAIGYLHSLN 120

IVYRDLKPEN ILLDSQGHVV LTDFGLCKEG VEPEGTTSTF CGTPEYLAPE VLRKEPYDRT 180

VDWWCLGAVL YEMIYSLPPF YSRDVGVMYD GILHKPLQLP PGKSDAVCSL LVGLLQKDQH 240

RRLGAIADFL EIKNHVFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013