EKS-TEN-00023

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00023

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	480.4	1.7E-144	24	291	268

Status

Unreviewed

Ensembl Protein

ENSTNIP00000015809

UniProt Accession

H3D5M0;

Protein Name

Protein Synonyms/Alias

Gene Name

PHKG2

Gene Synonyms/Alias

PHKG2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000012834	ENSTNIP00000015809	ENSTNIT00000016019

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

390

Protein Sequence
(FASTA)

MTKDIVVGDE LPDWVGAKEF YQKYDPKEVI GRGVSSVVRR CVHRHTGQEL AVKIIEITAE 60

KMTAQQLAEV KTSTLKEIQV LNMVKGHASI ITLIDSYEST TFIFLVFDLM RRGELFDYLT 120

EKVTLSEKET RSIMRALLEA VHYLHSLHIV HRDLKPENIL LDDHGHIKLS DFGFSVQLQP 180

GEKLKELCGT PGYLAPEILK CSMDDMHAGY GKEVDLWACG VILFTLLAGS PPFWHRKQML 240

MLRMIMEGRY QFSSPEWDDR SDTVKDLISR LLVLEPAARL TAEQALAHPL FRLYQKEDVR 300

LFSPRKTFRV LIVSVLACIR IYSRYQRVRP LTRDVLSRDP YSIRGVRKLI DGCAFRIYGH 360

WVKKGEQQNR AALFQNTAKI MLLGLEDLDP 390

Nucleotide Sequence
(FASTA)

ATGACCAAAG ACATTGTTGT TGGAGATGAA CTGCCAGACT GGGTGGGGGC CAAAGAGTTC 60

TACCAGAAAT ATGACCCCAA GGAGGTCATT GGCAGGGGGG TGAGCAGTGT GGTGCGCAGG 120

TGTGTGCACA GGCACACGGG TCAGGAGCTG GCAGTGAAGA TCATCGAGAT CACGGCGGAG 180

AAGATGACTG CTCAGCAGCT GGCGGAGGTG AAGACCTCCA CCCTGAAGGA GATCCAGGTC 240

CTCAACATGG TGAAGGGCCA CGCCTCCATC ATAACTCTGA TCGATTCCTA CGAATCCACC 300

ACCTTCATAT TTTTAGTCTT TGACCTCATG AGGAGAGGAG AGCTGTTTGA CTACCTAACA 360

GAGAAGGTGA CGCTGAGCGA GAAGGAAACC AGGAGTATTA TGCGAGCCCT GCTGGAGGCT 420

GTTCACTACC TCCACTCTCT CCACATTGTC CACCGTGACC TAAAACCTGA GAATATCCTG 480

CTGGATGATC ACGGACACAT TAAACTCTCG GACTTTGGTT TCTCTGTGCA GCTGCAGCCC 540

GGCGAAAAAC TTAAAGAGCT CTGTGGGACG CCTGGTTATT TAGCCCCTGA AATACTGAAG 600

TGTTCCATGG ACGACATGCA CGCCGGCTAT GGAAAAGAAG TGGATCTCTG GGCCTGTGGC 660

GTGATCCTTT TCACCCTGCT GGCTGGCTCG CCACCCTTCT GGCACCGCAA ACAGATGCTG 720

ATGCTGAGGA TGATCATGGA AGGCCGATAC CAGTTCAGCT CCCCGGAGTG GGACGACCGG 780

TCCGACACCG TCAAAGACCT GATTTCCAGG CTGCTGGTTT TGGAACCAGC CGCCCGTCTT 840

ACTGCCGAAC AAGCTCTGGC TCATCCTCTC TTCAGGCTGT ATCAGAAGGA GGACGTGCGA 900

CTGTTCAGTC CAAGGAAGAC ATTCAGGGTG TTGATCGTCA GCGTGCTGGC CTGTATCAGG 960

ATCTACAGCC GTTACCAAAG GGTGCGTCCT CTGACCAGGG ACGTGCTGTC CAGAGATCCC 1020

TACTCCATCC GCGGCGTCCG CAAGCTCATC GACGGCTGTG CCTTCCGCAT CTACGGACAC 1080

TGGGTGAAAA AGGGGGAGCA GCAGAACCGA GCCGCCCTCT TCCAGAACAC AGCTAAGATC 1140

ATGCTTCTGG GCCTGGAGGA CCTGGACCCC TGA 1173

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvsaeklseeevkelreatlkeveilrq  60

         y+pke++GrGvssvvrrc++++tgqe avkii+++aek++ +++ e++ +tlke+++l+

Q: 24    YDPKEVIGRGVSSVVRRCVHRHTGQELAVKIIEITAEKMTAQQLAEVKTSTLKEIQVLNM  83

         9***********************************************************

S: 61    vsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleavey  120

         v Gh sii+l+d+yes++f+flvfdlm++Gelfdyltekvtlseketr+imralleav+y

Q: 84    VKGHASIITLIDSYESTTFIFLVFDLMRRGELFDYLTEKVTLSEKETRSIMRALLEAVHY  143

         ************************************************************

S: 121   lhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcsm  180

         lh+ +ivhrdlkpenilldd+ +iklsdfGfs+ql++Gekl+elcGtpgylapeilkcsm

Q: 144   LHSLHIVHRDLKPENILLDDHGHIKLSDFGFSVQLQPGEKLKELCGTPGYLAPEILKCSM  203

         ************************************************************

S: 181   deeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddisee  240

         d+ + Gy+kevdlwa+Gvil+tllaGsppfwhrkq+lmlr+imeG+yqf+spewdd+s++

Q: 204   DDMHAGYGKEVDLWACGVILFTLLAGSPPFWHRKQMLMLRMIMEGRYQFSSPEWDDRSDT  263

         ************************************************************

S: 241   vkdliskllvvdpekrltaeealahpff  268

         vkdlis+llv++p +rltae+alahp f

Q: 264   VKDLISRLLVLEPAARLTAEQALAHPLF  291

         **************************87

Domain Sequence
(FASTA)

YDPKEVIGRG VSSVVRRCVH RHTGQELAVK IIEITAEKMT AQQLAEVKTS TLKEIQVLNM 60

VKGHASIITL IDSYESTTFI FLVFDLMRRG ELFDYLTEKV TLSEKETRSI MRALLEAVHY 120

LHSLHIVHRD LKPENILLDD HGHIKLSDFG FSVQLQPGEK LKELCGTPGY LAPEILKCSM 180

DDMHAGYGKE VDLWACGVIL FTLLAGSPPF WHRKQMLMLR MIMEGRYQFS SPEWDDRSDT 240

VKDLISRLLV LEPAARLTAE QALAHPLF 268

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013