EKS-TEN-00061

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00061

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/VRK	372.9	8.4E-112	36	302	267

Status

Unreviewed

Ensembl Protein

ENSTNIP00000016397

UniProt Accession

H3D7A6;

Protein Name

Protein Synonyms/Alias

Gene Name

VRK2

Gene Synonyms/Alias

VRK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000013404	ENSTNIP00000016397	ENSTNIT00000016610

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

327

Protein Sequence
(FASTA)

FRFCSNSVGM APPKKGSLPE PLPEGFILSD TQKKQWRLGK IIGQGGFGLI YLASKDVDRP 60

VAADTAFVIK VEYLENGPLF SELKFYQRAA KPENIQKWQR SRGLHFLGIP TYWGTGVAEY 120

NNLSYRFMAM DRLGSDLQKI CERSGGQMKK ATVLQLGQRL VSVLEYIHEN EYVHGDIKAA 180

NLMLGYTDPE QVYLADYGLS YRYCPSGVHK EYKENPKKGH NGTIEYTSLD AHSGLDPSRR 240

GDLQILGFCL LHWLCGSLPW DDVLKDPIKV QKAKERLMDH LPHSVQHLST HSVSTDEVAK 300

FLLHVKTLAY HDKPDYQHLQ DVLSCGI 327

Nucleotide Sequence
(FASTA)

TTCCGTTTTT GCTCAAACTC AGTTGGAATG GCTCCACCAA AGAAGGGCTC GTTACCCGAA 60

CCGCTACCAG AGGGCTTCAT ATTGAGCGAC ACTCAGAAGA AGCAATGGAG GCTGGGCAAA 120

ATCATTGGTC AAGGGGGCTT TGGCCTGATC TATCTGGCCT CCAAGGATGT GGACAGACCT 180

GTTGCTGCAG ACACTGCCTT TGTCATAAAA GTGGAGTACT TAGAGAATGG GCCCCTGTTT 240

TCAGAGCTCA AGTTCTACCA GAGGGCAGCC AAACCAGAGA ACATTCAAAA ATGGCAGAGA 300

AGCAGAGGAC TGCACTTTCT GGGTATCCCG ACATACTGGG GAACTGGGGT GGCTGAATAT 360

AATAACTTGA GTTATCGTTT TATGGCCATG GACCGTCTGG GAAGCGACCT TCAGAAAATT 420

TGTGAGCGCA GCGGAGGTCA AATGAAAAAG GCCACAGTGC TTCAGCTGGG TCAAAGATTG 480

GTGAGTGTAC TGGAGTACAT CCATGAGAAC GAGTACGTCC ATGGGGACAT TAAAGCTGCC 540

AACCTGATGC TGGGCTACAC GGACCCTGAA CAGGTTTACC TGGCTGATTA TGGGCTGTCA 600

TACAGATACT GTCCCTCTGG GGTCCACAAA GAATACAAGG AAAATCCAAA GAAGGGCCAC 660

AATGGAACTA TTGAATACAC CAGCCTGGAT GCCCACAGTG GCCTTGATCC ATCCAGACGT 720

GGGGACCTCC AAATTTTGGG TTTTTGTCTT CTTCACTGGT TATGCGGCTC TCTGCCCTGG 780

GACGATGTAC TCAAAGACCC GATCAAGGTC CAGAAGGCCA AGGAGAGACT GATGGATCAT 840

TTGCCACACT CGGTCCAGCA CTTGTCGACA CACAGCGTCA GCACAGATGA GGTGGCCAAA 900

TTCCTCCTCC ATGTGAAAAC CCTGGCCTAC CATGATAAGC CAGACTACCA GCATCTCCAA 960

GACGTGCTGT CCTGCGGCAT C 981

Domain Profile

S: 1     wklgkkigkggfGeiyla..ltckkeekdaklvvkvepkenGpLfvelkfyqraakkeqi  58

         w+lgk ig+ggfG iyla   + + +  d+ +v+kve+ enGpLf+elkfyqraak+e+i

Q: 36    WRLGKIIGQGGFGLIYLAskDVDRPVAADTAFVIKVEYLENGPLFSELKFYQRAAKPENI  95

         9*****************7656667889999*****************************

S: 59    kkwkkkkklkllgiPtliasGlhefegekyRflvlprlgrdLqklleqngkrlsektvlq  118

         +kw++ + l++lgiPt++++G+ e+++ +yRf+ ++rlg+dLqk+ e++g+++++ tvlq

Q: 96    QKWQRSRGLHFLGIPTYWGTGVAEYNNLSYRFMAMDRLGSDLQKICERSGGQMKKATVLQ  155

         ************************************************************

S: 119   lavrlldvleylHeneYvHgdikAanllleeeeasqvyLvdyGlayrycpegkhkeyked  178

         l+ rl+ vley+HeneYvHgdikAanl+l++++++qvyL+dyGl+yrycp+g+hkeyke+

Q: 156   LGQRLVSVLEYIHENEYVHGDIKAANLMLGYTDPEQVYLADYGLSYRYCPSGVHKEYKEN  215

         ************************************************************

S: 179   krraHdGtleftslDaHkGvapsrRsDleiLgYcllkWltgkLPWeallkdpekvqkake  238

         +++ H+Gt+e+tslDaH G  psrR+Dl+iLg+cll+Wl+g+LPW + lkdp kvqkake

Q: 216   PKKGHNGTIEYTSLDAHSGLDPSRRGDLQILGFCLLHWLCGSLPWDDVLKDPIKVQKAKE  275

         ************************************************************

S: 239   kfldelpellkkllkkkssseelakyl  265

         +++d+lp+++++l ++++s+ e+ak+l

Q: 276   RLMDHLPHSVQHLSTHSVSTDEVAKFL  302

         *************************97

Domain Sequence
(FASTA)

WRLGKIIGQG GFGLIYLASK DVDRPVAADT AFVIKVEYLE NGPLFSELKF YQRAAKPENI 60

QKWQRSRGLH FLGIPTYWGT GVAEYNNLSY RFMAMDRLGS DLQKICERSG GQMKKATVLQ 120

LGQRLVSVLE YIHENEYVHG DIKAANLMLG YTDPEQVYLA DYGLSYRYCP SGVHKEYKEN 180

PKKGHNGTIE YTSLDAHSGL DPSRRGDLQI LGFCLLHWLC GSLPWDDVLK DPIKVQKAKE 240

RLMDHLPHSV QHLSTHSVST DEVAKFL 267

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>