EKS-TEN-00320

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00320

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	285.1	5.0E-85	18	271	254

Status

Unreviewed

Ensembl Protein

ENSTNIP00000017678

UniProt Accession

H3DAY6;

Protein Name

Protein Synonyms/Alias

Gene Name

NUAK2

Gene Synonyms/Alias

NUAK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000014650	ENSTNIP00000017678	ENSTNIT00000017901

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

567

Protein Sequence
(FASTA)

KKQAVKRHHH KHNLKHRYEF LETLGKGTYG KVKKARESSG RLVAIKSIRK DKIKDEQDLV 60

HIRREIEIMS AICHPHIITI YEVFENKDKI VIVMEYASRG DLYDYILGTD AVSDREARHF 120

SRLIMEAPHV AHVVVQNGIV HRDLKLENIL LDGGGHVKIA DFGLSNLYRG DEYLQTFCGS 180

PLYASPEIVN GRPYRGPEVD TWSLGVLLYT LVHGTMPFDG QNHQTLVQQI STGTYRKPSH 240

PSDACGLIRW MLMVNPERRA TIEEIAGHWW LNWGYQQLLT VRDQGRPRRE PGLASWLRRT 300

SRPLLENGSK MRCLLRSQGG SADVVRQRSL RRSRKENNVS QTVHEAGADA PPSKSILKRR 360

SSAKQKAPAD SSSCSAGLAD SAAPAGVLST ASLPRKGILK KPAEESGYYS SSPENSDSGG 420

GAPEARPSAP THRKGILKRN GKFSSGRMQE FGSLDQLAAS LPRCRARPSG AISEDSILSS 480

ESFDQLDLPE RVGPPARLET PAQPSMRGCV SADNLLDIQE DGSLEDGLMG PWTCYRSRVA 540

DSAFSITDCD HVTEAYKQAM VLRGPAA 567

Nucleotide Sequence
(FASTA)

AAAAAGCAGG CGGTGAAGAG ACACCACCAC AAACACAACC TGAAGCACAG GTACGAGTTC 60

CTGGAAACCC TGGGGAAAGG AACCTACGGA AAAGTGAAGA AAGCCAGGGA GAGTTCCGGC 120

CGGCTGGTTG CCATAAAGTC CATCAGAAAG GACAAGATCA AGGATGAGCA GGACCTGGTT 180

CACATCCGCA GGGAGATCGA GATCATGTCG GCAATCTGCC ACCCGCACAT CATCACCATC 240

TACGAAGTCT TTGAAAATAA GGACAAAATC GTGATTGTGA TGGAGTACGC CAGCAGAGGG 300

GACCTGTACG ACTACATCCT GGGCACCGAT GCTGTCTCTG ATCGGGAGGC CAGGCACTTC 360

TCAAGGCTGA TTATGGAGGC TCCGCATGTC GCACATGTAG TCGTACAGAA CGGAATCGTG 420

CACCGGGACC TGAAGCTGGA GAACATTTTA CTGGATGGCG GCGGACATGT GAAGATCGCC 480

GATTTCGGCC TGTCCAACCT CTACCGCGGC GACGAGTACC TGCAGACGTT TTGCGGCAGC 540

CCTCTCTACG CGTCCCCAGA GATCGTCAAC GGGCGGCCGT ACAGGGGCCC CGAGGTGGAC 600

ACCTGGTCCC TGGGCGTGCT GCTGTACACC TTGGTTCACG GCACCATGCC CTTCGACGGG 660

CAGAACCACC AGACCCTGGT CCAGCAGATC AGCACAGGGA CCTACAGGAA GCCCAGCCAC 720

CCCTCCGATG CGTGTGGGCT GATCCGTTGG ATGCTGATGG TGAATCCTGA GCGCAGAGCC 780

ACCATCGAAG AGATCGCTGG CCACTGGTGG CTCAACTGGG GCTACCAGCA GCTGCTGACG 840

GTGCGAGACC AAGGCCGGCC CCGCCGCGAA CCAGGCCTCG CCAGTTGGCT CCGGCGCACG 900

TCCAGGCCTC TGCTGGAGAA CGGCTCCAAG ATGCGCTGCC TGCTGCGCTC GCAGGGAGGC 960

AGCGCGGACG TGGTCCGGCA GCGCTCCCTG CGGCGCTCCC GCAAGGAGAA CAACGTCTCG 1020

CAGACTGTGC ACGAGGCCGG CGCCGACGCT CCGCCCTCCA AAAGCATCCT GAAGAGACGC 1080

AGCAGCGCCA AGCAGAAGGC GCCGGCCGAC TCCTCCTCCT GCAGCGCCGG TTTGGCGGAT 1140

TCGGCAGCAC CGGCCGGCGT CCTTTCCACC GCCTCGTTGC CCCGCAAGGG AATCCTGAAG 1200

AAGCCGGCGG AGGAGTCCGG GTACTACTCT TCGTCCCCGG AGAACAGCGA CTCCGGCGGC 1260

GGTGCGCCTG AAGCGCGCCC TTCGGCGCCC ACCCACAGAA AGGGCATCTT GAAGCGCAAC 1320

GGCAAGTTCT CCTCAGGCAG GATGCAGGAG TTCGGCTCCC TGGACCAGCT GGCCGCGTCC 1380

CTGCCCCGCT GCCGGGCCAG GCCCAGCGGC GCCATCAGCG AGGACAGCAT TCTCTCCTCC 1440

GAGTCCTTCG ACCAGCTGGA CCTCCCGGAG CGCGTCGGAC CGCCGGCGCG GCTGGAGACG 1500

CCGGCCCAGC CCAGCATGAG AGGATGCGTG TCGGCGGACA ACCTTCTGGA CATCCAGGAG 1560

GACGGGAGCC TGGAGGACGG CCTGATGGGG CCCTGGACCT GCTACAGGTC CAGGGTGGCC 1620

GACAGCGCCT TCTCCATCAC CGACTGCGAC CACGTGACCG AGGCCTACAA ACAGGCCATG 1680

GTCCTCCGGG GGCCCGCAGC C 1701

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y++l+tlG+g++gkVk+a+++  ++ va+K i+k+k+ +e+ l +i+rEiei++ + hp+

Q: 18    YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIkDEQDLVHIRREIEIMSAICHPH  76

         99***************9986.799**********996777899****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlh...s  116

         ii ++ev+e+k+k+++v+eyas+g+L+dyi  +  ++ +ear++ + +++a +  h   +

Q: 77    IITIYEVFENKDKIVIVMEYASRGDLYDYILGTDAVSDREARHFSRLIMEAPHVAHvvvQ  136

         ***************************************************777776679

S: 117   kgivHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYeg  176

         +givHrDlK+eN+lld  +++kiaDFGl+nl++ ++ l+tfcGsp Ya+Pe+++g++Y+g

Q: 137   NGIVHRDLKLENILLDGGGHVKIADFGLSNLYRGDEYLQTFCGSPLYASPEIVNGRPYRG  196

         9***********************************************************

S: 177   pkvDvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvd  236

         p+vD WslGv+Ly+lv g++Pfd++n ++l+++i++g+++ p++ s ++  L+r +L+v+

Q: 197   PEVDTWSLGVLLYTLVHGTMPFDGQNHQTLVQQISTGTYRKPSHPS-DACGLIRWMLMVN  255

         ********************************************66.5668*********

S: 237   pekRatieeilkhewl  252

         pe+Ratieei  h wl

Q: 256   PERRATIEEIAGHWWL  271

         ***************7

Domain Sequence
(FASTA)

YEFLETLGKG TYGKVKKARE SSGRLVAIKS IRKDKIKDEQ DLVHIRREIE IMSAICHPHI 60

ITIYEVFENK DKIVIVMEYA SRGDLYDYIL GTDAVSDREA RHFSRLIMEA PHVAHVVVQN 120

GIVHRDLKLE NILLDGGGHV KIADFGLSNL YRGDEYLQTF CGSPLYASPE IVNGRPYRGP 180

EVDTWSLGVL LYTLVHGTMP FDGQNHQTLV QQISTGTYRK PSHPSDACGL IRWMLMVNPE 240

RRATIEEIAG HWWL 254

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013