EKS-TEN-00425

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00425

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	310.9	7.7E-93	28	281	254

Status

Unreviewed

Ensembl Protein

ENSTNIP00000019287

UniProt Accession

H3DFJ3;

Protein Name

Protein Synonyms/Alias

Gene Name

TAOK1

Gene Synonyms/Alias

TAOK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000016195	ENSTNIP00000019287	ENSTNIT00000019516

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

998

Protein Sequence
(FASTA)

MPNSSRAGSL KDPEIADLFF KEDPEKLFTD LREIGHGSFG AVYFARNGRT NEVVAIKKMS 60

YSGKQSNEKW QDIIKEVKYL QKIQHPNCIE YKGCYLREHT AWLVMEYCLG SASDLLEVHK 120

KPLQEVEIAA ITHGALRGLA YLHSHNMIHR DIKAGNILLT EPGQVKLADF GSASIACPAN 180

SFVGTPYWMA PEVILAMDEG QYEGKVDIWS LGITCIELAE RKPPLFNMNA MSALYHIAQN 240

DSPMLQSSEW TEYFRNFVDS CLQKISQDRP NSEELLKHAF VQRERPESVL VDLINRTKDA 300

VRELDNLQYR KMKKILFQEA HNGPTTEAQD EEEEPEHVVG RTGTVNSAGS NQSIPSMSIS 360

ASSQSSSVNS LTDAGDDKSE ADMEGDHTVM SVIHLKPEEQ INNEETEPNN RPTEPQSQPA 420

QTPRPKRNRE HFATIRTASV LTRQIKEHEQ DSELREQILG YKRMRRQHQK QLMALENKLK 480

AEMDEHRLRL DKELENQRNT FAQEMEKLIK KHQAAMEKYA KTFSNDEKKF QQHIQSQQKK 540

ELNSFLESQK REYKLRKEQL KVELNENQST PKKEKQEWLS KQKENFQHYQ AEEEANLQRR 600

QRQYLELECR RFKRRILIAR HNIEQDLVRE ELNKRQTQKD LEHAMLLRHH ESMQELEFRQ 660

LNNIQKTRTE LVRLQHQTEL TNQQEYNKRR ERELRRKHAM EVRQQPKSLK SKELQIKKQF 720

QDTCKIQTRQ YKALRNQLLE TMPKSEHKAI LKRMKQEQHR KLAILAEQYD HSINEMLSTQ 780

ALRLDETQEA QCQALRIQLQ QELELLNAYQ SKIKMQTDAQ HDRERKDLEQ RVSLRRALLE 840

HKIEEEMMSL QNERLARIQS LLERQAREVE AFGSESIRLG FSNMVLSNIS PEALSHSFPG 900

APGGWSPHQQ QQSGSPQGPH WGSPGGASMQ QGWGPGLQGD GGPSPLGHSS AVSRLSGGLQ 960

NNPQAMGRTP TGARSEQGMS RSTSVTSQIS NGSHLSYT 998

Nucleotide Sequence
(FASTA)

ATGCCCAACA GCAGCCGGGC GGGGAGCCTG AAGGACCCCG AAATCGCTGA CCTCTTCTTT 60

AAGGAAGACC CAGAAAAGCT CTTCACAGAC CTTCGTGAGA TCGGGCATGG CAGCTTTGGC 120

GCTGTTTATT TTGCACGAAA TGGGCGGACA AATGAGGTGG TGGCCATCAA GAAGATGTCT 180

TACAGTGGAA AGCAGTCCAA CGAGAAATGG CAGGACATCA TCAAAGAAGT GAAATACCTG 240

CAGAAAATAC AACACCCAAA CTGCATAGAA TACAAAGGAT GTTACCTACG GGAGCACACC 300

GCCTGGCTGG TCATGGAATA TTGCCTTGGC TCCGCTTCGG ATCTGTTAGA AGTTCACAAG 360

AAACCTTTGC AGGAAGTGGA AATCGCTGCA ATTACTCACG GCGCTCTTCG AGGGTTGGCT 420

TACTTACACT CCCACAACAT GATTCACCGC GATATCAAGG CAGGGAACAT CTTACTGACG 480

GAGCCAGGGC AAGTCAAACT AGCAGATTTT GGATCTGCGT CCATCGCCTG TCCGGCAAAC 540

TCCTTCGTCG GGACGCCATA TTGGATGGCC CCAGAAGTCA TTTTAGCCAT GGATGAGGGT 600

CAGTATGAAG GAAAGGTGGA CATTTGGTCT TTGGGAATCA CATGCATTGA ATTAGCTGAG 660

AGGAAGCCTC CCCTCTTCAA CATGAATGCG ATGAGTGCCT TATACCACAT AGCACAGAAC 720

GACAGCCCTA TGCTGCAGTC TAGTGAATGG ACGGAGTATT TCCGAAACTT TGTAGATTCT 780

TGCCTTCAGA AAATTTCTCA GGACAGACCA AACTCTGAGG AGTTGTTAAA GCACGCATTT 840

GTCCAACGCG AAAGACCAGA ATCGGTTCTG GTCGATCTGA TCAATCGGAC CAAGGACGCC 900

GTGCGGGAGC TGGACAATCT TCAGTATCGC AAAATGAAGA AGATCCTGTT TCAGGAAGCT 960

CATAATGGCC CGACGACGGA GGCACAAGAC GAGGAGGAGG AGCCAGAACA CGTTGTGGGC 1020

AGGACTGGTA CGGTGAACAG CGCAGGAAGC AACCAGTCTA TTCCCAGTAT GTCGATCAGC 1080

GCCAGCTCCC AGAGCAGTTC TGTCAACAGT CTGACGGATG CAGGCGACGA CAAGAGCGAG 1140

GCGGACATGG AGGGAGACCA CACCGTCATG TCTGTCATAC ACCTCAAACC AGAGGAACAG 1200

ATAAATAATG AAGAGACGGA ACCCAACAAC AGGCCGACGG AGCCTCAGTC CCAACCAGCG 1260

CAAACTCCAC GACCCAAACG CAACCGCGAG CATTTTGCTA CGATACGCAC GGCCTCAGTG 1320

CTCACTCGCC AGATAAAAGA ACACGAGCAG GATTCTGAGT TAAGGGAGCA GATACTGGGC 1380

TACAAGCGGA TGAGACGGCA GCACCAGAAA CAGCTGATGG CTCTGGAAAA CAAGCTGAAG 1440

GCGGAGATGG ACGAGCACAG ACTGCGTCTA GACAAGGAGC TGGAGAACCA GAGGAACACC 1500

TTTGCCCAAG AGATGGAGAA GCTGATAAAG AAGCACCAGG CAGCCATGGA GAAATATGCA 1560

AAGACATTTA GCAACGATGA AAAGAAGTTT CAACAGCACA TTCAGAGTCA GCAGAAGAAG 1620

GAACTGAATA GTTTCCTTGA ATCTCAGAAG CGAGAGTACA AACTCCGTAA GGAACAACTT 1680

AAAGTGGAGC TGAACGAAAA CCAGTCAACA CCCAAGAAAG AAAAGCAGGA GTGGTTGTCA 1740

AAGCAGAAGG AGAACTTCCA ACACTACCAA GCAGAGGAGG AGGCCAACCT GCAGCGCAGA 1800

CAGAGACAGT ATCTGGAACT GGAATGTCGC AGGTTCAAAC GGAGGATCCT GATCGCGCGC 1860

CACAACATTG AGCAGGATTT AGTACGAGAG GAGCTGAACA AACGTCAGAC CCAGAAGGAT 1920

CTGGAACACG CCATGCTGCT CCGGCACCAC GAATCTATGC AAGAGCTGGA GTTCCGCCAG 1980

CTCAACAACA TCCAAAAGAC GAGGACCGAG CTGGTCCGTC TGCAGCACCA GACCGAGCTC 2040

ACCAACCAGC AGGAGTACAA CAAGAGGAGG GAGCGGGAAC TCCGACGCAA GCACGCCATG 2100

GAGGTCCGCC AACAGCCCAA GAGCCTTAAG TCCAAAGAGC TACAGATCAA GAAGCAGTTT 2160

CAGGATACTT GTAAGATCCA GACCAGGCAG TACAAGGCGC TGAGAAACCA ACTGTTGGAG 2220

ACCATGCCCA AATCAGAGCA CAAGGCTATC CTGAAACGGA TGAAGCAGGA GCAGCACCGC 2280

AAGCTGGCCA TCTTGGCCGA GCAGTACGAC CACTCCATCA ACGAGATGCT GTCAACTCAG 2340

GCGCTACGTT TGGATGAGAC TCAGGAGGCT CAGTGCCAAG CCCTACGGAT TCAACTGCAA 2400

CAGGAGCTGG AACTTCTCAA TGCCTACCAG AGCAAGATCA AGATGCAGAC GGATGCTCAA 2460

CACGATCGCG AGAGGAAGGA CCTGGAGCAG AGGGTGTCGC TCCGGAGGGC CCTGCTGGAA 2520

CACAAGATTG AAGAGGAGAT GATGTCTCTG CAAAACGAAC GACTGGCGCG AATCCAGAGC 2580

CTGCTGGAGC GCCAGGCCCG CGAAGTTGAA GCTTTCGGTT CGGAGAGCAT TCGCCTGGGC 2640

TTCAGCAACA TGGTGCTATC TAACATCTCC CCAGAGGCCC TGAGCCACAG CTTTCCTGGG 2700

GCTCCGGGTG GGTGGAGTCC TCATCAGCAG CAGCAGTCCG GGAGCCCTCA GGGGCCACAC 2760

TGGGGCAGTC CAGGAGGGGC ATCTATGCAG CAGGGCTGGG GTCCGGGTCT GCAGGGAGAT 2820

GGAGGCCCGT CGCCATTAGG CCATTCGTCA GCAGTCTCCC GCCTCAGCGG AGGTTTACAA 2880

AACAACCCTC AAGCGATGGG ACGGACACCC ACAGGGGCTC GCAGCGAGCA GGGCATGAGC 2940

AGGAGTACGA GCGTCACCTC TCAGATATCT AACGGATCCC ACCTCTCCTA CACATAG 2997

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq...ekleelqkeisvlkklkhpn  57

         ++ l+eig+G++g+vy ar+ +t+e+vaikk++++ +   ek+++++ke++ l+k++hpn

Q: 28    FTDLREIGHGSFGAVYFARNGRTNEVVAIKKMSYSGKqsnEKWQDIIKEVKYLQKIQHPN  87

         67899*****************************988899********************

S: 58    iveylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHsk  117

          +ey +++l+e++ wlvmey+  Gs+sdl++ ++k++l+E +ia+i++++l++L+ylHs+

Q: 88    CIEYKGCYLREHTAWLVMEYCL-GSASDLLE-VHKKPLQEVEIAAITHGALRGLAYLHSH  145

         *********************7.********.****************************

S: 118   kviHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqe.ekg  176

         ++iHrdika+niLlte g+VkL+dfg+a+         +++vgtpywmAPEvi ++ e +

Q: 146   NMIHRDIKAGNILLTEPGQVKLADFGSASIACP----ANSFVGTPYWMAPEVILAMdEGQ  201

         **************************9998888....69**************9887999

S: 177   YdekaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvek  236

         Y+ k+DiwslGIt+ielae++pP++++++++al++i++n++p l+s+ ++++ f++fv++

Q: 202   YEGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPMLQSS-EWTEYFRNFVDS  260

         ********************************************777.************

S: 237   clqknpekRpsasellkhkFl  257

         clqk  ++Rp+++ellkh+F+

Q: 261   CLQKISQDRPNSEELLKHAFV  281

         ********************7

Domain Sequence
(FASTA)

FTDLREIGHG SFGAVYFARN GRTNEVVAIK KMSYSGKQSN EKWQDIIKEV KYLQKIQHPN 60

CIEYKGCYLR EHTAWLVMEY CLGSASDLLE VHKKPLQEVE IAAITHGALR GLAYLHSHNM 120

IHRDIKAGNI LLTEPGQVKL ADFGSASIAC PANSFVGTPY WMAPEVILAM DEGQYEGKVD 180

IWSLGITCIE LAERKPPLFN MNAMSALYHI AQNDSPMLQS SEWTEYFRNF VDSCLQKISQ 240

DRPNSEELLK HAFV 254

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013