EKS-TEN-00197

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00197

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TLK	603.6	4.9E-182	409	687	279

Status

Unreviewed

Ensembl Protein

ENSTNIP00000020050

UniProt Accession

H3DHQ6;

Protein Name

Protein Synonyms/Alias

Gene Name

TLK1 (2 of 2)

Gene Synonyms/Alias

TLK1 (2 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000016931	ENSTNIP00000020050	ENSTNIT00000020281

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

717

Protein Sequence
(FASTA)

SGIMEELHSL DPRRQELLEA RFMGGVSGST GGSTGSTTGG TKALINNECS NHSFGSLGSL 60

SDKESETPEK KQSETRGRKR KPDIQSESSQ GKLNVRGPKI SDYFDFQGGN GSSPVRGVPP 120

VIRSPQNSHS QSTQGTAVRQ NSSSPPSLTF GDHITHPKQQ ALKIVQTDLT VLKLAALEST 180

KNLDLEKKEG RIDDLLRANC DLRRQIDEQQ KLLEKYKERL NKCITMSKKL LIEKSTQEKQ 240

ACREKSMQDR LRLGHFTTVR HGASFTEQWT DGYAFQNLVK QQEWINQQRE DIERQRKLLA 300

KRKPPSSSNS QALTANSEPK QRKTKAMNGA ESDPFLKPSL PQLLTLAEYH EQEEIFKLRL 360

GHLKKEEAEI QAELERLERV RNLHIRELKR INNEDSSQFK DHPTLNERYL LLHLLGRGGF 420

SEVYKAFDLI EQRYAAVKVH QLNKNWREEK KENYHKHACR EYRIHKELDH PRIVKLYDYF 480

SLDTDSFCTV MEYCEGNDLD FYLKQHKLMS EKEARSIVMQ IVNALKYLNE IKPPIIHYDL 540

KPGNILLVNG TACGEIKITD FGLSKIMDDD NYGVDGMDLT SQGAGTYWYL PPECFVVGKE 600

PPKISNKVDV WSVGIIFFQC LYGRKPFGHN QSQQDILQEN TILKATDVQF PVKPVASNEA 660

KAFIRRCLAY RKEDRIDVHQ MSSDPYLLPH IRRSSSSGNL QTSAASSGLA SSSVTSY 717

Nucleotide Sequence
(FASTA)

TCAGGAATAA TGGAGGAGCT GCACAGTCTG GACCCCCGGA GACAAGAGTT GCTGGAGGCC 60

CGCTTCATGG GTGGGGTCAG CGGCAGCACA GGAGGCAGCA CCGGCAGCAC CACCGGGGGG 120

ACCAAAGCTT TGATTAATAA TGAATGTTCA AATCACAGTT TTGGAAGCCT TGGATCCCTA 180

AGCGACAAGG AATCAGAGAC CCCAGAGAAA AAACAGTCAG AAACAAGAGG CAGAAAAAGG 240

AAACCAGACA TCCAGTCAGA GAGCAGCCAA GGAAAGTTAA ATGTTCGAGG ACCCAAAATA 300

AGTGATTATT TTGATTTCCA GGGAGGAAAC GGGTCCAGTC CAGTGAGGGG TGTCCCGCCG 360

GTGATCCGCT CACCGCAGAA CTCACATTCC CAGTCCACTC AGGGCACAGC TGTTAGACAA 420

AATAGTTCTT CTCCCCCGAG CCTGACTTTT GGGGACCACA TAACTCATCC AAAGCAACAA 480

GCACTCAAAA TTGTACAGAC TGATCTTACC GTGTTGAAGT TGGCTGCCCT TGAAAGCACT 540

AAAAATTTAG ACCTTGAGAA GAAGGAGGGA AGAATAGACG ATTTGTTAAG GGCAAACTGT 600

GATCTCAGGA GACAGATAGA TGAACAACAA AAGTTACTTG AAAAGTACAA AGAACGCTTG 660

AATAAATGCA TCACCATGAG CAAAAAGTTG CTCATCGAAA AGAGCACCCA GGAAAAGCAG 720

GCATGTCGGG AGAAGAGCAT GCAGGACAGA CTTCGTTTAG GCCATTTCAC CACAGTCAGA 780

CACGGAGCGT CATTTACAGA ACAGTGGACT GATGGATATG CTTTCCAGAA TCTAGTGAAA 840

CAGCAAGAGT GGATAAACCA ACAGAGAGAG GACATCGAGA GGCAGAGAAA GCTGCTTGCC 900

AAGAGGAAAC CGCCATCTTC AAGCAACTCC CAAGCTCTGA CTGCTAATTC TGAGCCAAAG 960

CAACGCAAAA CCAAGGCGAT GAACGGAGCT GAAAGTGATC CTTTTCTAAA ACCCAGCCTA 1020

CCTCAGCTGC TGACACTAGC AGAGTACCAC GAGCAGGAGG AGATCTTTAA ACTGCGTCTG 1080

GGGCATCTTA AAAAGGAGGA AGCTGAAATC CAGGCAGAGC TGGAGCGTCT GGAGAGAGTG 1140

CGCAACCTTC ACATTCGAGA GCTGAAAAGA ATAAATAATG AAGACAGCTC GCAATTTAAG 1200

GATCACCCAA CGCTGAATGA GCGATATCTG CTCCTACACC TTCTAGGAAG AGGAGGATTT 1260

AGTGAAGTTT ACAAGGCTTT TGACTTGATT GAACAACGAT ACGCTGCTGT GAAAGTCCAC 1320

CAACTTAACA AGAACTGGAG GGAGGAGAAG AAGGAGAACT ATCACAAACA TGCGTGTCGC 1380

GAGTACAGAA TACACAAGGA ACTGGACCAC CCACGGATCG TGAAACTTTA TGACTACTTC 1440

TCACTGGACA CAGACTCGTT TTGCACTGTC ATGGAGTATT GTGAAGGCAA CGACTTGGAT 1500

TTCTACTTGA AGCAACATAA GCTCATGTCT GAAAAAGAGG CACGGTCCAT AGTCATGCAG 1560

ATTGTGAACG CATTAAAATA TCTGAATGAA ATCAAACCCC CCATCATCCA TTACGACCTC 1620

AAGCCAGGTA ATATCTTGTT GGTGAATGGA ACGGCATGTG GAGAGATCAA AATCACCGAC 1680

TTTGGTTTGT CCAAAATCAT GGATGATGAC AACTACGGCG TGGATGGGAT GGATCTGACA 1740

TCACAGGGTG CAGGAACATA TTGGTACCTT CCTCCTGAAT GCTTTGTGGT TGGTAAAGAG 1800

CCACCAAAGA TCTCCAACAA GGTGGATGTG TGGTCTGTGG GCATCATTTT CTTCCAGTGT 1860

CTGTACGGAA GGAAGCCTTT TGGCCACAAT CAGTCGCAAC AAGACATTCT GCAGGAGAAC 1920

ACCATATTAA AAGCTACAGA TGTCCAGTTC CCAGTCAAGC CAGTTGCCAG TAATGAAGCC 1980

AAAGCTTTTA TAAGACGCTG CCTGGCATAC AGGAAGGAGG ACCGCATCGA CGTTCACCAG 2040

ATGTCCAGCG ATCCCTACCT GCTCCCACAC ATACGGAGGT CGAGCTCGTC TGGAAATCTG 2100

CAGACGAGCG CCGCCAGCTC AGGACTCGCC TCATCTAGCG TCACCTCATA TTGA 2154

Domain Profile

S: 1     ylllkllgkggfsevykafdlkeqryvavkihqlnkdwkdekkenyvkhalreyrihkel  60

         ylll+llg+ggfsevykafdl eqry+avk+hqlnk+w++ekkeny+kha+reyrihkel

Q: 409   YLLLHLLGRGGFSEVYKAFDLIEQRYAAVKVHQLNKNWREEKKENYHKHACREYRIHKEL  468

         9***********************************************************

S: 61    dhprivklydllsldtdsfctvleyvegndldfylkqhkllsekearsiimqivsalkyl  120

         dhprivklyd++sldtdsfctv+ey+egndldfylkqhkl+sekearsi+mqiv+alkyl

Q: 469   DHPRIVKLYDYFSLDTDSFCTVMEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALKYL  528

         ************************************************************

S: 121   neikppiihydlkpgnillvegtacgeikitdfglskimdddsydsddgleltsqgagty  180

         neikppiihydlkpgnillv+gtacgeikitdfglskimddd+y++d g++ltsqgagty

Q: 529   NEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDNYGVD-GMDLTSQGAGTY  587

         *********************************************99.************

S: 181   wylppecfvvgkeppkisnkvdvwsvgvifyqclygkkpfghnqsqqdileentilkate  240

         wylppecfvvgkeppkisnkvdvwsvg+if+qclyg+kpfghnqsqqdil+entilkat+

Q: 588   WYLPPECFVVGKEPPKISNKVDVWSVGIIFFQCLYGRKPFGHNQSQQDILQENTILKATD  647

         ************************************************************

S: 241   vqfpskpvvsseakafirrclayrkedridvqqlakdeyl  280

         vqfp+kpv s+eakafirrclayrkedridv+q+++d+yl

Q: 648   VQFPVKPVASNEAKAFIRRCLAYRKEDRIDVHQMSSDPYL  687

         **************************************97

Domain Sequence
(FASTA)

YLLLHLLGRG GFSEVYKAFD LIEQRYAAVK VHQLNKNWRE EKKENYHKHA CREYRIHKEL 60

DHPRIVKLYD YFSLDTDSFC TVMEYCEGND LDFYLKQHKL MSEKEARSIV MQIVNALKYL 120

NEIKPPIIHY DLKPGNILLV NGTACGEIKI TDFGLSKIMD DDNYGVDGMD LTSQGAGTYW 180

YLPPECFVVG KEPPKISNKV DVWSVGIIFF QCLYGRKPFG HNQSQQDILQ ENTILKATDV 240

QFPVKPVASN EAKAFIRRCL AYRKEDRIDV HQMSSDPYL 279

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013