EKS-TEN-00371

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00371

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	463.2	2.9E-139	512	773	262

Status

Unreviewed

Ensembl Protein

ENSTNIP00000001242

UniProt Accession

H3C306;

Protein Name

Protein Synonyms/Alias

Gene Name

ERN1

Gene Synonyms/Alias

ERN1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000017990	ENSTNIP00000021154	ENSTNIT00000021387
ENSTNIG00000017990	ENSTNIP00000001242	ENSTNIT00000002275
ENSTNIG00000017990	ENSTNIP00000002624	ENSTNIT00000002041
ENSTNIG00000017990	ENSTNIP00000001254	ENSTNIT00000003430

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

919

Protein Sequence
(FASTA)

MSRPSGKTHR ICVPVDYLGV WCFLQGFCGA STVSLPESLL FVSTLDGNLH AVSKKSGSIK 60

WTLKEDPVLQ VPTHVAEPAF LPDPNDGSLY SLGGKNSEGL TKLPFTIPEL VQASPCRSSD 120

GVLYMGKKQD LWYVVDLLTG EKQQTLTSSF AEMLCPSSSL LYLGRTEYTI TMYDTKSREL 180

RWNATYADYA STLPDDDTKY KMAHFVSNGD GLVVTVDSDS GDVQWVQNYN SPVVAIYIWQ 240

REALRKVAHT NVAVETLRYL TFMSGEFVVI HASVCGQRTK SAFTSAKMKA TLYVGKYSTS 300

LYASPSLVHD GVTVVAQPRG STFPMLEGPD SQETEEDKEC VITPSTSVKF NAALRKRHRV 360

NFMRNYLLLI GHHETPPEAH TKILIRTDIL PLVQKVNDSG MDDAPPPPLP ETSIQEPGTA 420

GRSARPEAPV DTMLKDMATI IFSTFLLAGW VAFVIIYPKS PPAPPTTPTS LCPSSEALLM 480

SVKKEVLVQM TPRPVLPPEE ESSVVRVGNI SFRPKEVLGH GAEGTIVYKG QFDNRPVAVK 540

RILPECFSFA DREVQLLRES DEHPNVIRYF CTERDRQFQY IAIELCAASL QEYVERKDFE 600

RHGLEPVMLL QQTMSGLTHL HSLNIVHRDL KPHNILVSMP NAHGRVRAMI SDFGLCKKLA 660

VGRHSFSRRS GVPGTEGWIA PEVLSEDCKD NPTCAVDIFS AGCVFYYVVS QGSHPFGRSL 720

QRQANILLGT YSLDQLQTDK HGDIVARDLI ERMLSVEPCK RPSAESVLKH PFFWSLEKEL 780

QFFQDVSDRI EKEPLDGSIV RQLERGGRAV VKGDWREHIT VPLQTDLRKF RSYKGGSVRD 840

LLRAMRNKKH HYRELPAEVQ ETLGSIPDDF VSYFTSRFPH LLLHTCLAMR SCASERAFLP 900

YYCSAEQLAE ARGHNLRPP 919

Nucleotide Sequence
(FASTA)

ATGTCGCGGC CCAGTGGGAA GACTCACAGG ATTTGTGTAC CAGTCGATTA TCTCGGTGTT 60

TGGTGTTTTT TGCAGGGCTT CTGCGGCGCC AGCACCGTGT CCCTCCCTGA AAGCCTGCTT 120

TTTGTGTCCA CCCTGGACGG GAACCTACAT GCTGTCAGCA AGAAATCAGG CTCTATCAAA 180

TGGACCCTTA AAGAAGATCC AGTTCTTCAG GTCCCCACAC ATGTGGCAGA ACCAGCGTTT 240

CTTCCTGACC CCAATGATGG CAGCCTGTAC TCTCTGGGAG GAAAGAACAG CGAAGGCCTC 300

ACAAAATTGC CCTTCACCAT TCCCGAGCTG GTTCAAGCGT CTCCCTGTCG CAGTTCAGAC 360

GGCGTTCTTT ACATGGGTAA GAAGCAGGAC CTGTGGTACG TGGTGGACCT GCTGACTGGC 420

GAGAAGCAGC AGACCCTCAC CTCCTCCTTC GCTGAGATGT TGTGTCCGTC CTCCTCTCTT 480

CTCTACCTGG GACGCACAGA ATACACCATC ACCATGTATG ACACCAAGAG CAGAGAGCTG 540

CGCTGGAACG CCACCTATGC CGACTATGCC TCCACGCTTC CCGACGATGA CACCAAATAC 600

AAGATGGCTC ATTTTGTCTC CAACGGCGAC GGCCTCGTCG TGACGGTGGA CAGCGACTCC 660

GGAGATGTTC AGTGGGTGCA GAACTACAAC TCCCCCGTGG TGGCCATTTA TATCTGGCAG 720

CGCGAGGCCC TCCGCAAGGT AGCCCACACC AACGTGGCCG TGGAAACCCT GCGCTACCTC 780

ACCTTCATGT CTGGAGAGTT TGTTGTAATT CACGCCTCAG TCTGTGGCCA AAGGACCAAA 840

TCAGCCTTTA CATCCGCGAA AATGAAGGCT ACTCTCTATG TGGGGAAATA CTCCACCAGT 900

CTGTATGCGT CCCCTTCATT GGTGCACGAC GGTGTCACTG TGGTGGCGCA GCCTCGCGGC 960

AGCACCTTCC CCATGCTGGA GGGTCCCGAC AGCCAGGAGA CCGAAGAGGA CAAAGAGTGT 1020

GTCATCACCC CCAGCACCAG TGTCAAGTTC AACGCTGCGC TCCGAAAAAG ACACCGCGTC 1080

AACTTCATGA GGAACTACCT GCTCCTCATC GGTCATCACG AGACGCCTCC TGAGGCTCAC 1140

ACCAAGATTC TGATCCGTAC TGACATCCTT CCCCTGGTCC AGAAGGTGAA TGATAGCGGC 1200

ATGGATGATG CCCCGCCCCC TCCTCTGCCT GAAACCTCCA TCCAAGAGCC TGGGACTGCT 1260

GGGCGAAGCG CCCGTCCGGA GGCTCCTGTA GACACCATGC TAAAGGACAT GGCCACCATC 1320

ATCTTTTCCA CTTTCCTCCT GGCTGGCTGG GTAGCCTTTG TCATTATCTA CCCCAAATCA 1380

CCCCCCGCGC CTCCAACCAC TCCAACCTCT CTGTGTCCGA GCTCGGAGGC TCTCCTTATG 1440

AGCGTGAAGA AGGAGGTGCT GGTTCAGATG ACTCCCAGGC CGGTTCTACC ACCAGAGGAG 1500

GAGTCCAGTG TGGTCAGAGT CGGCAACATA TCGTTCCGTC CTAAAGAGGT GTTGGGTCAC 1560

GGTGCTGAGG GAACCATAGT GTACAAGGGA CAGTTTGACA ACCGTCCAGT GGCGGTGAAA 1620

AGGATCCTCC CCGAGTGCTT CAGCTTCGCA GACCGCGAAG TGCAGCTGCT GAGGGAGTCT 1680

GACGAACACC CCAACGTCAT TCGCTACTTC TGCACCGAGA GGGATCGACA GTTCCAGTAC 1740

ATCGCTATCG AGCTGTGTGC AGCCTCCCTG CAGGAGTATG TGGAACGGAA GGACTTTGAG 1800

CGTCACGGGC TGGAACCGGT GATGCTTCTT CAGCAGACCA TGTCGGGCCT GACCCACCTG 1860

CACTCTCTGA ACATCGTCCA CAGAGACCTG AAGCCCCACA ACATCCTGGT CTCCATGCCC 1920

AACGCTCACG GCAGGGTCCG GGCCATGATC TCAGACTTCG GCTTGTGTAA GAAGCTGGCG 1980

GTGGGCCGTC ACAGTTTCAG CAGGAGGTCC GGGGTTCCGG GCACCGAGGG CTGGATCGCT 2040

CCGGAGGTTC TCAGCGAGGA CTGCAAAGAC AACCCGACCT GTGCCGTGGA CATCTTCTCT 2100

GCCGGCTGCG TCTTTTACTA CGTGGTGTCC CAGGGAAGTC ATCCTTTTGG CAGGTCTCTG 2160

CAGAGACAGG CCAACATCTT GCTGGGGACA TACAGCCTGG ACCAGCTGCA AACAGACAAA 2220

CACGGAGACA TTGTAGCCAG AGATCTAATA GAGCGGATGC TGAGCGTGGA ACCTTGCAAG 2280

CGGCCCTCGG CTGAGAGTGT CCTCAAGCAT CCGTTCTTCT GGAGCTTGGA GAAGGAGCTG 2340

CAGTTCTTTC AGGATGTGAG CGACAGAATA GAGAAGGAGC CACTGGACGG CTCCATCGTT 2400

AGACAGCTGG AGAGAGGAGG CAGGGCCGTC GTCAAGGGCG ACTGGAGGGA ACACATCACC 2460

GTTCCGCTGC AAACAGATTT GAGGAAGTTT CGCTCCTACA AAGGCGGGTC GGTCCGAGAC 2520

CTGCTCCGAG CGATGAGGAA CAAGAAGCAC CACTACCGAG AGCTGCCTGC CGAGGTTCAG 2580

GAGACCCTCG GCTCCATCCC CGACGACTTT GTGTCCTACT TCACCTCCCG CTTCCCCCAC 2640

CTGCTGCTGC ACACCTGCCT GGCCATGCGG AGCTGTGCAT CCGAGAGAGC CTTCCTGCCT 2700

TATTACTGCA GCGCAGAGCA GCTCGCGGAA GCGCGGGGCC ACAACCTCAG GCCCCCG 2757

Domain Profile

S: 1     fspkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfc  60

         f pk+vlG+GaeGt+v++G+f++r+vavkr+l+e++++a+rev+llresdehpnviryfc

Q: 512   FRPKEVLGHGAEGTIVYKGQFDNRPVAVKRILPECFSFADREVQLLRESDEHPNVIRYFC  571

         679*********************************************************

S: 61    tekdrqfryialelcaaslqdyvedkdlelqkelepisllkqiasGlahlhslkivhrdl  120

         te+drqf+yia+elcaaslq+yve kd+e +++lep+ ll+q++sGl+hlhsl+ivhrdl

Q: 572   TERDRQFQYIAIELCAASLQEYVERKDFE-RHGLEPVMLLQQTMSGLTHLHSLNIVHRDL  630

         *****************************.99****************************

S: 121   kpqnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltke  180

         kp+nil+s+p+a+g++r++isdfGlckkl+vG++sfsrrsgv+GteGwiape+l+e++k+

Q: 631   KPHNILVSMPNAHGRVRAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEVLSEDCKD  690

         ************************************************************

S: 181   rltsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedli  240

         ++t avdifs+Gcvfyyv+s+G+hpfG sl+rqanil g++sld+l+++k+ +++a+dli

Q: 691   NPTCAVDIFSAGCVFYYVVSQGSHPFGRSLQRQANILLGTYSLDQLQTDKHGDIVARDLI  750

         ************************************************************

S: 241   skmidkdplkrpsakkvlkhplf  263

         ++m++++p krpsa+ vlkhp+f

Q: 751   ERMLSVEPCKRPSAESVLKHPFF  773

         **********************9

Domain Sequence
(FASTA)

FRPKEVLGHG AEGTIVYKGQ FDNRPVAVKR ILPECFSFAD REVQLLRESD EHPNVIRYFC 60

TERDRQFQYI AIELCAASLQ EYVERKDFER HGLEPVMLLQ QTMSGLTHLH SLNIVHRDLK 120

PHNILVSMPN AHGRVRAMIS DFGLCKKLAV GRHSFSRRSG VPGTEGWIAP EVLSEDCKDN 180

PTCAVDIFSA GCVFYYVVSQ GSHPFGRSLQ RQANILLGTY SLDQLQTDKH GDIVARDLIE 240

RMLSVEPCKR PSAESVLKHP FF 262

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR011047	; Quinonprotein_ADH-like.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 5.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013