EKS-TEN-00087

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00087

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	371.5	2.8E-111	19	316	298

Status

Unreviewed

Ensembl Protein

ENSTNIP00000021832

UniProt Accession

Q4RH34;

Protein Name

Protein Synonyms/Alias

Chromosome undetermined SCAF15070, whole genome shotgun sequence.;

Gene Name

CDK9 (2 of 2)

Gene Synonyms/Alias

CDK9 (2 of 2); GSTENG00034533001;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000018657	ENSTNIP00000021832	ENSTNIT00000022068

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

372

Protein Sequence
(FASTA)

MSKYYDGVEF PFCDEFSKYE KMAKIGQGTF GEVFKAKHRQ TGKKVALKKV LMENEKEGFP 60

ITALREIKIL QLLKHENVVN LIEICRTKAT LYNRYKGSIY LVFDFCEHDL AGLLSNSNVK 120

FTLAEIKKVM QMLLNGLYYI HRNKILHRDM KAANVLITRD GVLKLADFGL ARAFSLAKNS 180

QGNRYTNRVV TLWYRPPELL LGERDYGPPI DLWGAGCIMA EMWTRSPIMQ GNTEQHQLTL 240

ISQLCGSITT EVWPTVDKKY ELYQKMELPK GQKRKVKDRL KAYVKDPYAL DLIDKLLVLD 300

PAQRTDSDDA LNHDFFWTDP MPSDLKSMLS THNTSMFEYL APPRRRGHMP QQQPNQNRNP 360

ATTSQTEFDR VF 372

Nucleotide Sequence
(FASTA)

ATGTCGAAGT ATTACGACGG AGTTGAATTC CCCTTTTGTG ATGAATTCTC CAAATATGAA 60

AAAATGGCTA AAATTGGACA AGGGACGTTC GGGGAGGTTT TCAAAGCCAA GCACAGGCAG 120

ACGGGCAAGA AGGTCGCCCT GAAGAAAGTC CTGATGGAAA ACGAGAAAGA AGGGTTCCCA 180

ATCACAGCTC TGAGAGAAAT CAAGATCCTG CAGCTGCTCA AACACGAGAA CGTGGTCAAC 240

CTGATCGAGA TCTGCAGAAC CAAAGCGACG CTGTACAACC GCTACAAAGG CAGCATCTAC 300

CTGGTGTTTG ACTTCTGCGA GCACGACCTG GCCGGCCTGT TGAGCAACTC CAACGTCAAG 360

TTCACCCTGG CCGAGATCAA GAAGGTCATG CAGATGCTGC TCAACGGCCT CTACTACATC 420

CACCGGAACA AGATCCTCCA CAGAGACATG AAAGCCGCCA ACGTGCTCAT CACCCGGGAC 480

GGCGTGCTGA AGCTGGCCGA CTTCGGCCTG GCCCGGGCCT TCAGCCTGGC CAAGAACAGC 540

CAGGGGAACC GCTACACCAA CCGCGTGGTG ACGCTGTGGT ACCGACCTCC GGAGCTGCTG 600

CTGGGCGAGC GCGACTACGG CCCCCCCATC GACCTGTGGG GGGCCGGCTG CATCATGGCC 660

GAGATGTGGA CTCGGAGCCC CATCATGCAA GGCAACACGG AGCAGCACCA GCTGACTCTG 720

ATCAGCCAGC TGTGCGGCTC CATCACCACC GAGGTGTGGC CCACGGTGGA TAAGAAGTAT 780

GAGCTCTACC AGAAGATGGA GCTGCCCAAA GGACAGAAGA GGAAGGTGAA GGACCGGCTG 840

AAGGCCTACG TGAAGGACCC GTACGCCCTG GACCTGATCG ACAAGCTGCT GGTGCTGGAC 900

CCGGCCCAGC GCACCGACAG CGACGACGCG CTCAACCACG ACTTCTTCTG GACCGACCCC 960

ATGCCCTCAG ACCTGAAGAG CATGCTGTCC ACTCACAACA CCTCCATGTT TGAGTACCTG 1020

GCCCCGCCCA GGAGGAGGGG CCACATGCCG CAGCAGCAGC CCAACCAGAA CCGGAACCCC 1080

GCCACCACCA GCCAGACGGA GTTTGACCGC GTCTTTTAG 1119

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         yek++kig+Gt+g+v+kak+++tg++vAlKk+ +e+ekeg+pitalrEi++l+ lkh+n+

Q: 19    YEKMAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENV  78

         99**********************************************************

S: 61    vkLlevva.......kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqllegl  113

         v+L+e++        + k ++yLvf+f+e+dL+ ll++++  k++l+e+k+++++ll+gl

Q: 79    VNLIEICRtkatlynRYKGSIYLVFDFCEHDLAGLLSNSNV-KFTLAEIKKVMQMLLNGL  137

         ********99999988889**********************.******************

S: 114   aylHsnkilHRDlKpqNlLiskegklklaDfGlaraf....ssplktytkevvTlwYraP  169

          y+H+nkilHRD+K++N+Li+++g+lklaDfGlaraf    +s+ ++yt++vvTlwYr+P

Q: 138   YYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFslakNSQGNRYTNRVVTLWYRPP  197

         *************************************7665555558*************

S: 170   elLlgakeYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevs  229

         elLlg+++Y+  +D+W++gci+ae++tr+p++qg++e++ql+ i++l+g+++++vwp+v

Q: 198   ELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLTLISQLCGSITTEVWPTVD  257

         **********************************************************97

S: 230   k.lpeyk.ksfpkkkkkklkekvkklkek..aldllekllaldpkkRisakealqhkyf  284

         k ++ y+ +++pk +k+k+k+++k++ ++  aldl++kll ldp++R+++++al+h++f

Q: 258   KkYELYQkMELPKGQKRKVKDRLKAYVKDpyALDLIDKLLVLDPAQRTDSDDALNHDFF  316

         526777789999*9999******988766579*************************98

Domain Sequence
(FASTA)

YEKMAKIGQG TFGEVFKAKH RQTGKKVALK KVLMENEKEG FPITALREIK ILQLLKHENV 60

VNLIEICRTK ATLYNRYKGS IYLVFDFCEH DLAGLLSNSN VKFTLAEIKK VMQMLLNGLY 120

YIHRNKILHR DMKAANVLIT RDGVLKLADF GLARAFSLAK NSQGNRYTNR VVTLWYRPPE 180

LLLGERDYGP PIDLWGAGCI MAEMWTRSPI MQGNTEQHQL TLISQLCGSI TTEVWPTVDK 240

KYELYQKMEL PKGQKRKVKD RLKAYVKDPY ALDLIDKLLV LDPAQRTDSD DALNHDFF 298

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013