EKS-TEN-00239

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00239

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Ryk	463.6	2.0E-139	278	543	266

Status

Unreviewed

Ensembl Protein

ENSTNIP00000021849

UniProt Accession

H3DMV1;

Protein Name

Protein Synonyms/Alias

Gene Name

RYK

Gene Synonyms/Alias

RYK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000018673	ENSTNIP00000021849	ENSTNIT00000022085

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

554

Protein Sequence
(FASTA)

PSYLPDNNSG PSVNIYMSLE EVKKLLGLDA ELYYVRNNIV NHQALSFPLP VPSETNSLHF 60

TWHSRTKVDY RLGFHTENPE AMSQPRSNIS AHGELPQSPS VFRVDLVCSG KVDEEAVLTV 120

QLNLTTPTSN YMVLNFKRSK MCYKMVNVIW CAVLLTSALF ALVDGAMAPT TSTQVFYISV 180

SVCCIVIFLV AIFLAIMHLH SMKRVEVEES VSDSGSSQGL SQPSTHTTQY LRADTPNNAA 240

PVTNPPSLRI EKNDLRSVTL LEAKARVKDL SVSRDRVTLG DVLQEGTFGQ IFHGVLLDEK 300

DPSKEKQVFV KTVKDHASEV QVTMMLTESL KLRGLHHRNL LPISHVCTED GEKPMVLLPF 360

VAWGNLKLFL RQCKLAEANN PQSVSQQDLV SMAIQIACGM SYLSRREVIH KDLAARNCVI 420

DDSMQVKISD NALARDLFPM DYHCLGDNEN RPVRWMALES LLHNDFSSLS DVWAFGVTLW 480

ELMTLGQTPY VDIDPFEMSA YLKDGYRIAQ PINCPDELFA VMACCWALDP EERPKFQQLV 540

QCLTEFHSAL GAYV 554

Nucleotide Sequence
(FASTA)

CCGAGTTACC TTCCCGACAA CAACAGCGGC CCGAGTGTGA ACATCTACAT GAGCCTGGAG 60

GAGGTGAAGA AACTTCTGGG TCTGGATGCG GAGCTGTATT ATGTACGCAA CAACATCGTC 120

AATCATCAAG CTCTCTCCTT CCCGCTGCCT GTGCCCAGTG AGACCAACAG CCTCCACTTC 180

ACCTGGCATT CCAGAACCAA GGTGGACTAC AGGCTGGGCT TTCACACGGA GAACCCGGAG 240

GCCATGAGCC AACCCCGGAG CAACATCTCC GCCCACGGGG AGCTGCCCCA GAGTCCTTCT 300

GTGTTCAGGG TGGACCTGGT CTGCTCCGGG AAGGTGGACG AAGAGGCGGT CCTCACGGTG 360

CAGCTCAACC TGACCACCCC CACCAGCAAC TACATGGTGC TCAACTTCAA GAGGAGCAAA 420

ATGTGCTACA AAATGGTGAA TGTCATCTGG TGTGCTGTCC TCCTAACATC TGCTCTGTTT 480

GCACTAGTCG ATGGCGCGAT GGCACCCACC ACCTCCACCC AGGTCTTCTA CATCAGCGTC 540

AGTGTGTGCT GCATCGTCAT TTTCCTCGTG GCCATCTTCT TAGCCATCAT GCATCTACAC 600

AGCATGAAGC GGGTGGAGGT GGAGGAGAGC GTCAGTGACA GCGGCAGCTC CCAGGGGCTG 660

TCGCAGCCGT CCACACACAC CACCCAGTAC CTGAGGGCCG ACACCCCCAA CAACGCAGCC 720

CCCGTCACCA ACCCCCCGTC CCTCCGGATA GAGAAGAACG ACCTGAGGAG CGTGACTCTG 780

CTGGAGGCCA AGGCCAGGGT GAAGGACCTG TCCGTGTCCC GGGACAGGGT CACCCTGGGG 840

GACGTTCTGC AGGAAGGAAC CTTTGGCCAG ATCTTTCATG GTGTGCTGTT GGACGAGAAG 900

GACCCCAGCA AGGAGAAGCA GGTGTTTGTG AAGACGGTGA AAGATCACGC GTCCGAGGTG 960

CAGGTGACCA TGATGTTGAC GGAAAGCCTC AAGCTGCGTG GTCTCCACCA CAGAAACCTG 1020

CTGCCGATCA GTCACGTTTG TACTGAAGAC GGGGAGAAGC CCATGGTGCT CCTGCCCTTC 1080

GTGGCCTGGG GCAATCTCAA GCTTTTCCTG CGGCAGTGCA AGTTAGCGGA GGCCAACAAT 1140

CCCCAGTCTG TCTCCCAGCA GGACCTGGTT TCCATGGCCA TCCAGATTGC TTGTGGAATG 1200

AGCTACTTGT CCCGCAGGGA GGTGATCCAC AAGGACCTGG CAGCCAGGAA CTGTGTCATC 1260

GACGATAGCA TGCAGGTGAA GATTAGCGAC AACGCCCTGG CCAGAGACCT GTTTCCCATG 1320

GACTACCACT GCCTGGGCGA CAACGAGAAC CGCCCGGTGC GCTGGATGGC CCTGGAGAGC 1380

CTGCTCCACA ACGACTTCTC CAGCCTGAGC GACGTGTGGG CCTTCGGCGT GACGCTGTGG 1440

GAGCTGATGA CTCTGGGCCA GACGCCCTAC GTGGACATCG ACCCCTTCGA GATGTCGGCC 1500

TACCTGAAGG ACGGCTACAG AATAGCTCAA CCCATCAACT GTCCGGACGA GTTGTTCGCG 1560

GTGATGGCGT GCTGCTGGGC CCTGGACCCG GAGGAAAGGC CCAAGTTCCA GCAGCTGGTT 1620

CAGTGTCTGA CCGAGTTCCA CTCCGCTCTG GGCGCCTACG TCTGA 1665

Domain Profile

S: 2     rlkellqeGtfGriyrGkledekdtnkekavlvktvkdqaseiqvalllqealllygvsh  61

         +l ++lqeGtfG+i++G l dekd++kek+v+vktvkd+ase+qv+++l+e+l+l+g++h

Q: 278   TLGDVLQEGTFGQIFHGVLLDEKDPSKEKQVFVKTVKDHASEVQVTMMLTESLKLRGLHH  337

         67799*******************************************************

S: 62    rnilsvllvsieeaekPlvvypalnkgnlkkflricklkdkekaqalstkqlvelaiqia  121

         rn+l++ +v++e+ ekP+v++p  ++gnlk flr+ckl +++++q++s+++lv++aiqia

Q: 338   RNLLPISHVCTEDGEKPMVLLPFVAWGNLKLFLRQCKLAEANNPQSVSQQDLVSMAIQIA  397

         ************************************************************

S: 122   salaylhkrevvhkdiaarncviddelqvkltdsalsrdlfPadydclGdnenrPlkWls  181

         ++++yl +rev+hkd+aarncvidd +qvk++d+al+rdlfP+dy+clGdnenrP++W++

Q: 398   CGMSYLSRREVIHKDLAARNCVIDDSMQVKISDNALARDLFPMDYHCLGDNENRPVRWMA  457

         ************************************************************

S: 182   lealqkeeyssasdvWalGvllWelvtlgksPyaeidpfeleaylkdGyrlaqPvncPde  241

         le+l ++ +ss sdvWa+Gv+lWel+tlg++Py++idpfe++aylkdGyr+aqP+ncPde

Q: 458   LESLLHNDFSSLSDVWAFGVTLWELMTLGQTPYVDIDPFEMSAYLKDGYRIAQPINCPDE  517

         ************************************************************

S: 242   lftvmaccWallpeerPsfeqlvscl  267

         lf+vmaccWal+peerP+f+qlv+cl

Q: 518   LFAVMACCWALDPEERPKFQQLVQCL  543

         *************************8

Domain Sequence
(FASTA)

TLGDVLQEGT FGQIFHGVLL DEKDPSKEKQ VFVKTVKDHA SEVQVTMMLT ESLKLRGLHH 60

RNLLPISHVC TEDGEKPMVL LPFVAWGNLK LFLRQCKLAE ANNPQSVSQQ DLVSMAIQIA 120

CGMSYLSRRE VIHKDLAARN CVIDDSMQVK ISDNALARDL FPMDYHCLGD NENRPVRWMA 180

LESLLHNDFS SLSDVWAFGV TLWELMTLGQ TPYVDIDPFE MSAYLKDGYR IAQPINCPDE 240

LFAVMACCWA LDPEERPKFQ QLVQCL 266

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.
IPR003306	; WIF.

Pfam

PF07714	; Pkinase_Tyr; 1.
PF02019	; WIF; 1.

SMARTs

SM00219

; TyrKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.
PS50814	; WIF; 1.

Prints

PR00109

; TYRKINASE.

Created Date

20-Feb-2013