EKS-TEN-00362

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00362

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	429.5	6.6E-129	226	513	288

Status

Unreviewed

Ensembl Protein

ENSTNIP00000021866

UniProt Accession

H3DMW8;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR1A (1 of 2)

Gene Synonyms/Alias

BMPR1A (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000018688	ENSTNIP00000021866	ENSTNIT00000022102

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

524

Protein Sequence
(FASTA)

KATLLYCLLI FSLFRELRSA AGQNPDYVLQ GTGVKAEDST IAPEDAARFL SCYCSGHCPE 60

DATNNTCQTN GQCFAIIEED EHGEPLLTSG CMKYEGSHFQ CKDSPNAQSR RTIECCNTDF 120

CNRELQPTLP PLAPIGNAAW GSPNWLAFLI SMTVCCCMLI CVAVVCYYRY KWQSERQRYH 180

KDHRDLEQEV FIPAGESLRD LIHQSQSSGS GSGLPLLVQR TIAKQIQMMR QIGKGRYGEV 240

WLGRWRGEKV AVKVFFTREE ASWFRETEIY QTVLMRHDNI LGFIAADIKG TGAFTQLFLI 300

TDYHENGSLY DYLKLSTLDT HMLLRLAYSA ACGLCHLHTE IYGTQGKPAI AHRDLKSKNI 360

LIKKNGSCCI ADLGLAVKFN SDTNEVDVPL STRVGTRRYM APEVLNESLN KNHFQAYIMA 420

DIYSYGLVIW EMARRCVTGG MVEDYQLPYY DMVPPDPSYE DMLEVVCVKG LRPTVSNRWN 480

SDECLRAMLK LMSECWALNP ASRLTILRVK KTLAKMVESQ DIKV 524

Nucleotide Sequence
(FASTA)

AAAGCCACGC TTCTTTACTG CCTATTGATC TTCAGCCTGT TCAGGGAGCT TAGATCAGCT 60

GCGGGTCAGA ACCCCGACTA CGTCCTACAG GGGACGGGGG TCAAGGCCGA GGACTCCACC 120

ATCGCCCCGG AGGACGCCGC CCGCTTCCTG AGCTGCTACT GCTCTGGACA CTGTCCCGAG 180

GACGCCACCA ACAACACCTG CCAGACCAAC GGACAGTGTT TCGCCATCAT CGAGGAGGAC 240

GAGCACGGAG AACCGCTGCT GACCTCAGGC TGCATGAAGT ACGAAGGCTC CCACTTCCAG 300

TGCAAGGACT CTCCCAACGC CCAGAGCAGG AGGACCATCG AGTGCTGCAA CACTGACTTC 360

TGCAACCGGG AGCTGCAGCC AACGCTGCCC CCGCTGGCCC CCATCGGTAA CGCAGCCTGG 420

GGCAGTCCCA ACTGGCTGGC CTTCCTCATC TCCATGACCG TCTGCTGCTG CATGCTCATC 480

TGTGTGGCCG TGGTCTGTTA CTACAGGTAC AAGTGGCAGA GTGAGCGTCA GCGCTACCAC 540

AAGGATCACA GGGACCTGGA GCAGGAGGTC TTCATCCCTG CTGGGGAGTC TCTCAGGGAC 600

CTGATCCACC AATCGCAGAG CTCCGGCAGC GGCTCGGGGC TCCCCCTGCT GGTGCAGCGA 660

ACCATCGCCA AGCAGATTCA GATGATGCGT CAGATCGGTA AGGGGCGTTA CGGCGAGGTG 720

TGGCTGGGCC GCTGGCGGGG CGAGAAGGTG GCCGTCAAGG TGTTCTTCAC GCGCGAAGAG 780

GCCAGCTGGT TCAGAGAGAC GGAGATCTAC CAGACGGTCC TGATGAGACA TGACAACATT 840

CTGGGCTTCA TCGCGGCGGA CATCAAGGGC ACAGGCGCCT TCACGCAGCT CTTCCTCATC 900

ACCGACTACC ACGAGAACGG CTCGCTGTAC GACTACCTGA AGCTGAGCAC GCTGGACACG 960

CACATGCTGC TGCGGCTGGC GTACTCGGCG GCGTGCGGCC TCTGCCACCT GCACACGGAG 1020

ATCTACGGCA CGCAGGGGAA GCCCGCCATC GCCCACCGAG ACCTGAAGAG CAAGAACATC 1080

CTGATCAAGA AGAACGGGAG CTGCTGCATC GCCGACCTGG GCCTGGCCGT CAAGTTCAAC 1140

AGCGACACCA ATGAAGTGGA CGTCCCTCTG AGCACGCGTG TGGGGACGCG GCGCTACATG 1200

GCCCCCGAGG TCCTGAACGA GAGCCTGAAC AAGAACCACT TCCAGGCCTA CATCATGGCC 1260

GACATCTACA GCTACGGACT CGTCATCTGG GAGATGGCCA GGCGCTGCGT GACAGGAGGG 1320

ATGGTGGAGG ACTACCAGCT GCCCTACTAC GACATGGTCC CACCCGACCC GTCCTACGAG 1380

GACATGCTGG AGGTGGTGTG TGTCAAAGGT CTGAGGCCCA CCGTGTCCAA CCGCTGGAAC 1440

AGTGACGAGT GTCTCCGTGC CATGCTGAAG CTGATGTCCG AGTGCTGGGC TCTTAACCCC 1500

GCCTCCCGCC TCACCATCCT GCGAGTGAAG AAGACGCTGG CGAAGATGGT GGAGTCCCAG 1560

GACATCAAAG TCTGA 1575

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         ++++++igkGrygeVw +++rge+vAvK+f+t++easw+rE+eiyqtvl+rh+nil+fia

Q: 226   IQMMRQIGKGRYGEVWLGRWRGEKVAVKVFFTREEASWFRETEIYQTVLMRHDNILGFIA  285

         799*********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k ++  t+l+l+t+yhe+gsL+dyLk +tld++ llrla+s+a+Gl+hLH+ei gt+

Q: 286   ADIKGTGAFTQLFLITDYHENGSLYDYLKLSTLDTHMLLRLAYSAACGLCHLHTEIYGTQ  345

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  KpaiaHRDlkskNil+kk+++cciaDlGLa+k++++++e+d+  +++vGt+RYmaPE

Q: 346   G--KPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDVPLSTRVGTRRYMAPE  403

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vl+e+ln ++f+a+ +aD+Ys gLv+WE+a+Rc + +++ve+y+lp++++v+ dPs+e+m

Q: 404   VLNESLNKNHFQAYIMADIYSYGLVIWEMARRCVT-GGMVEDYQLPYYDMVPPDPSYEDM  462

         ***********************************.************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

          evv++k lrP+++++w+++e+l+++ kl++ecW+ +p++Rlt lrvkk+l

Q: 463   LEVVCVKGLRPTVSNRWNSDECLRAMLKLMSECWALNPASRLTILRVKKTL  513

         *************************************************97

Domain Sequence
(FASTA)

IQMMRQIGKG RYGEVWLGRW RGEKVAVKVF FTREEASWFR ETEIYQTVLM RHDNILGFIA 60

ADIKGTGAFT QLFLITDYHE NGSLYDYLKL STLDTHMLLR LAYSAACGLC HLHTEIYGTQ 120

GKPAIAHRDL KSKNILIKKN GSCCIADLGL AVKFNSDTNE VDVPLSTRVG TRRYMAPEVL 180

NESLNKNHFQ AYIMADIYSY GLVIWEMARR CVTGGMVEDY QLPYYDMVPP DPSYEDMLEV 240

VCVKGLRPTV SNRWNSDECL RAMLKLMSEC WALNPASRLT ILRVKKTL 288

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013