EKS-TEN-00303

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00303

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	378.0	2.1E-113	26	277	252

Status

Unreviewed

Ensembl Protein

ENSTNIP00000002019

UniProt Accession

H3DNS2;

Protein Name

Protein Synonyms/Alias

Gene Name

MARK4

Gene Synonyms/Alias

MARK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000018983	ENSTNIP00000022171	ENSTNIT00000022409
ENSTNIG00000018983	ENSTNIP00000002019	ENSTNIT00000002446

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

781

Protein Sequence
(FASTA)

SSRSLGARCR NSIALCSDET PHIGNYRLLK TIGKGNFAKV KLARHILTGR EVAIKIIDKT 60

QLNPTSLQKL FREVRIMKTL NHPNIVQLFE VIETEKTLYL IMEYASGGEV FDYLVAHGRM 120

KEKEARAKFR QIVSAVHYCH QKNIVHRDLK AEMLLLDADS NIKIADFGFS NEFSVGSKLD 180

TSCGSPPYAA PELFQGKKYD GPEVDIWSLG VILYTLVSGS LPFDGQNLKE LRERVLRGKY 240

RIPFYMSTDC EGILRRFLVL NPAKRCSLEQ IMKDKWINIG YEGDELTAHI EPVEDFNDTS 300

RIDVMVGMGF TREEIRDSLN TQKYNEVTAT YLLLGRKNDT ENVVTRSSSS LSLARVRPGT 360

VTNGTAASSS AGAKAQRSAS TYHRQRRHSD FCGPGVSTST HPKRSPSGVS EGVGLKEERL 420

SVRKPSTSTI GSRNIPTPSS PMVSSAHNPN KAEIPDRRKD MTSTTNNIPA SAMTRRNTYV 480

CTDRANADRH SLLQNGKETR IKDLKHGRVA SSVPSMSPRR DETLSAHDVT TARPCIKYPR 540

CSDSDAAYVP ACGFISLSHR LPPASPSTHS IAGASGASSS SSTPSSRLSR GTTVRSTFHG 600

GQIRDRRPPS HAPPGSPTPS HDASPLPHAR TRATTNLLSK LTSKLTRRVT LDPTKRQSSS 660

HTDTTALRSS SRHLPGHQKA SEPRTPRCGW DVRVRSPRDP AEVVLALREA AQGCGCQVHL 720

AGPFLLSCTH GVAGARVAFE AEVCQLPSGL GQSSGVRFKR LWGAPLAFRD IATKVSKELE 780

L 781

Nucleotide Sequence
(FASTA)

TCCAGCCGCT CTCTCGGCGC ACGATGTCGC AACTCCATCG CTTTGTGTTC AGACGAGACG 60

CCGCACATCG GGAACTACCG GCTCCTGAAG ACCATCGGCA AGGGAAACTT TGCCAAGGTC 120

AAACTGGCAC GGCACATCCT GACTGGTCGA GAGGTTGCAA TAAAGATCAT CGATAAAACC 180

CAGCTTAACC CCACCAGTCT GCAGAAGTTG TTTCGAGAGG TACGCATCAT GAAGACTCTG 240

AATCATCCAA ACATAGTTCA ATTGTTTGAG GTGATCGAGA CTGAGAAGAC TTTATATCTG 300

ATCATGGAGT ATGCCAGCGG AGGTGAAGTG TTTGACTACC TCGTGGCTCA TGGCAGAATG 360

AAGGAGAAAG AGGCCAGAGC CAAGTTCCGA CAGATTGTTT CTGCTGTGCA CTACTGTCAT 420

CAGAAGAACA TTGTTCACAG AGACTTGAAG GCAGAAATGT TGCTGTTAGA TGCTGATTCC 480

AACATCAAAA TAGCTGACTT TGGTTTCAGT AACGAGTTTT CCGTGGGCAG TAAACTGGAC 540

ACCTCCTGCG GCTCCCCTCC ATATGCTGCT CCAGAGCTCT TTCAGGGAAA AAAGTACGAT 600

GGTCCAGAGG TGGACATCTG GAGCCTGGGT GTCATCTTAT ACACACTGGT CAGCGGCTCT 660

TTGCCCTTTG ATGGACAAAA CCTAAAGGAA CTGCGGGAGC GTGTCTTGAG AGGGAAGTAC 720

CGTATACCGT TCTACATGTC TACAGACTGT GAAGGAATCC TGCGTCGCTT CCTGGTTCTT 780

AACCCTGCCA AACGCTGCTC GCTCGAGCAA ATAATGAAAG ATAAGTGGAT CAATATTGGG 840

TATGAAGGTG ACGAGCTCAC GGCCCACATT GAGCCGGTTG AGGACTTCAA CGACACCAGT 900

CGCATCGATG TCATGGTTGG GATGGGGTTC ACCAGGGAGG AGATCAGAGA TTCACTCAAC 960

ACTCAGAAGT ATAATGAAGT CACCGCTACG TACCTGCTGC TGGGACGCAA GAACGACACT 1020

GAGAACGTGG TGACTCGGTC GAGCAGCAGC CTGAGTCTCG CTCGGGTCCG ACCCGGCACC 1080

GTCACCAACG GTACCGCAGC GTCTTCTTCG GCGGGCGCCA AGGCGCAGCG CAGTGCCTCC 1140

ACCTACCATC GCCAGAGACG CCACTCGGAT TTCTGCGGTC CTGGAGTTTC CACCTCCACC 1200

CATCCCAAGC GGAGTCCCAG TGGTGTCAGC GAAGGCGTAG GCCTGAAAGA GGAGCGCCTG 1260

TCGGTCCGCA AACCCAGCAC CAGCACCATC GGATCGCGAA ACATCCCCAC CCCCTCCAGT 1320

CCCATGGTTA GCTCCGCCCA CAACCCCAAC AAGGCGGAGA TACCGGACCG CCGAAAGGAC 1380

ATGACCTCCA CCACAAATAA CATCCCGGCC AGTGCCATGA CGCGAAGGAA CACCTATGTG 1440

TGTACCGACC GAGCCAACGC TGACAGGCAC TCCTTGCTTC AGAACGGCAA GGAAACCAGG 1500

ATAAAGGACT TAAAGCACGG ACGAGTGGCC TCGTCTGTGC CCTCTATGAG CCCACGGAGG 1560

GATGAAACAC TGAGTGCACA TGACGTGACC ACAGCGCGCC CTTGCATTAA ATATCCTCGG 1620

TGCAGTGATT CAGATGCCGC CTATGTGCCC GCGTGTGGCT TCATCTCCTT ATCCCACCGT 1680

CTCCCTCCCG CCTCCCCTTC GACGCACAGC ATCGCTGGTG CCTCCGGAGC CTCCTCCTCC 1740

TCCTCGACGC CATCCTCCCG CCTGTCCAGG GGAACCACGG TGAGGAGCAC CTTCCACGGG 1800

GGGCAGATCC GGGACCGCAG GCCTCCCTCC CACGCCCCCC CTGGCTCCCC GACACCCTCC 1860

CATGACGCCA GCCCGCTGCC CCACGCCAGG ACTCGGGCCA CCACTAACTT ATTAAGCAAA 1920

CTGACTTCCA AGTTGACCCG CAGGGTCACT CTTGACCCTA CTAAACGTCA GAGCTCAAGC 1980

CATACAGACA CGACCGCTCT CCGCTCTTCC AGTCGCCATC TACCTGGGCA TCAGAAAGCG 2040

TCCGAGCCCC GGACCCCCCG ATGCGGCTGG GATGTGAGGG TGCGGAGTCC CCGCGACCCA 2100

GCCGAGGTGG TGCTAGCGCT CCGCGAGGCG GCTCAGGGTT GCGGCTGCCA GGTCCACCTG 2160

GCGGGGCCCT TTCTCCTGTC CTGCACCCAC GGAGTCGCCG GGGCCCGTGT GGCATTTGAG 2220

GCGGAGGTCT GCCAGCTGCC CAGCGGGCTG GGCCAGAGCA GCGGTGTGAG GTTCAAGCGT 2280

CTGTGGGGGG CACCTTTAGC CTTTAGAGAC ATTGCCACCA AAGTGTCCAA GGAGCTGGAA 2340

CTCTGA 2346

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpni  60

         y+llkt+G+g+f+kVkla+h +t+++va+Kii+k++l+ +sl+k++rE++i+k+l+hpni

Q: 26    YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKTLNHPNI  85

         99**********************************************************

S: 61    ikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgiv  120

         ++l+eviet+k+lyl++eyasgge+fdy++++gr+kekear+ f+q+vsav+Y+h+k+iv

Q: 86    VQLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVHYCHQKNIV  145

         ************************************************************

S: 121   HrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvD  180

         HrDlK+e llld+++nikiaDFG++n+f+ g++l+t+cGsppYaaPel++gkkY+gp+vD

Q: 146   HRDLKAEMLLLDADSNIKIADFGFSNEFSVGSKLDTSCGSPPYAAPELFQGKKYDGPEVD  205

         ************************************************************

S: 181   vWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpekR  240

         +WslGv+Ly+lv+g+lPfd++nlkel+e++l+gk++ip+++s+++e +lr++Lv +p+kR

Q: 206   IWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEGILRRFLVLNPAKR  265

         ************************************************************

S: 241   atieeilkhewl  252

         +++e+i+k++w+

Q: 266   CSLEQIMKDKWI  277

         ***********7

Domain Sequence
(FASTA)

YRLLKTIGKG NFAKVKLARH ILTGREVAIK IIDKTQLNPT SLQKLFREVR IMKTLNHPNI 60

VQLFEVIETE KTLYLIMEYA SGGEVFDYLV AHGRMKEKEA RAKFRQIVSA VHYCHQKNIV 120

HRDLKAEMLL LDADSNIKIA DFGFSNEFSV GSKLDTSCGS PPYAAPELFQ GKKYDGPEVD 180

IWSLGVILYT LVSGSLPFDG QNLKELRERV LRGKYRIPFY MSTDCEGILR RFLVLNPAKR 240

CSLEQIMKDK WI 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Canis familiaris"; ?>Danio rerio"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Pongo abelii"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR001772	; Kinase-assoc_KA1.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR015940	; UBA/transl_elong_EF1B_N_euk.

Pfam

PF02149	; KA1; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220	; S_TKc; 1.
SM00165	; UBA; 1.

Prosites

PS50032	; KA1; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS50030	; UBA; 1.

Prints

Created Date

20-Feb-2013