EKS-TEN-00034

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00034

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/Trio	329.1	2.2E-98	2745	3000	256

Status

Unreviewed

Ensembl Protein

ENSTNIP00000022321

UniProt Accession

H3DP71;

Protein Name

Protein Synonyms/Alias

Gene Name

TRIO (3 of 3)

Gene Synonyms/Alias

TRIO (3 of 3);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000019124	ENSTNIP00000022320	ENSTNIT00000022559
ENSTNIG00000019124	ENSTNIP00000022321	ENSTNIT00000022560

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

3047

Protein Sequence
(FASTA)

MKAIDVLPIL KEKVAFLSGG RDRRGGPVLT FPARSNHDRI RPEDLRRLIA YLATIPSEEV 60

ARHGFTVIVD MRGSKWDSIK PLLKILQESF PSCIHVALII KPDNFWQKQR TNFGSSKFEF 120

ETVMVSLEGL SKIVDPSQLT ADFEGSLEYN HDDWIEVRLS FETFASDAAR ALARLEELQD 180

TLSQRDLPRD LEGARRLMEE HAALKKRATK ASVEELDTQG RRLLQRLQAQ ASGGGSVNAD 240

AHNLIAKVSG LLDKLHGTRQ NLQQLWHMRK LKLDQCFQLR LFEQDAEKMF DWIMHNKGLF 300

LTSYTEIGGN HQHAVELQTQ HNHFAMNCMN VYVNINRIMS VGNRLLESGH YASQQIQQIS 360

GQLEQEWKAF AAALDERSTL LEMSASFHQK ADQYMSKVEP WCKACGEGEL PSELQDLEDT 420

IHHHQGLYEH ITTAYSEVSQ DGKSLLDKLQ RPLTPGSADS LMASANYSKA VHHVLDIIHE 480

VLHHQRQLEN IWQHRKVRLH QRLQLCVFQQ EVQQVLDWIE NHGEAFLSKH TGVGKSLHRA 540

RALQKRHEDF EEVAQNTYTN ADKLLEAAEQ LAQTGECDPE EIYQAAHQLE DRIQDFVRRV 600

EQRKVLLDMS VAFHTHVKEL WTWLEELQKE LLDDVYAESV EAVQDLIKRF GQQQQTTLQA 660

TVNVIKEGED LIQQLRDSAI SSNKTPHNSS MAHIESVLQQ LDEAQGQMEE LFQERKIKLE 720

LFLQLRIFER DAIDIISDLE SWNEELSQQM SDFDTEDLTL AEQRLQHHAD KALTMNNLTY 780

DVIHQGQELL QYVTEVQASG VELLCDRDVD MATRVQDLLE FLHEKQQELD LAAEQHRRHL 840

EQCVQLRHLQ AEVKQVLGWI RNGESMLNAG LITASSLQEA EQLQKEHEQF QHAIEENTSS 900

FQVYKFVLPL FSQLAHEMEL FLTLYPKVAD HWQQLMLKME DRLKLVNASV AFYKTSEQVC 960

SVLESLEQEY KREEDWCGGA DKLGPNSESD HVTPMISKHL EQKEAFLKAC TLARRNADVF 1020

LKYLHRNSVN MPGMLSHIKA PETQVKNILN ELLQRENRVL HFWTMRKRRL DQCQQYVVFE 1080

RSAKQALEWI HDTGEFYLST HTSTGSSIHH TQELLKEHED FQITAKQTKE RVKLLIQLAD 1140

GFCDKGHAHA LEIKKWVSSV DKRYRDFSLR MDKYRTSLET ALGISSDSNK ASKELQLDII 1200

PASAPGSEVK LRDAAHELNE EKRKSARRKE FIMAELIQTE KAYVRDLREC LDTYLWEMTS 1260

GVEEIPAGIV NKEHIIFGNM QDLYEFHHNI FLKELEKYEQ LPEDVGHCFV TWADKFQMYV 1320

SYCKNKPDST QLILEHAGAY FDEIQQRHRL ANSISSYLIK PVQRITKYQL LLKELLTCCE 1380

EGKGEIKDGL EVMLSVPKKA NDAMHLSMLE GFDGNIDSQG ELILQESFQV WDPKTLIRKG 1440

RDRHLFLFEM SLVFSKEVKD SNGRSKYLYK SKLFTSELGV TEHVEGDPCK FARATDPVNE 1500

SPLTRRRVLP QASSIENKQD WIKHIREVIQ ERTVHLRGAL KEPIHIPKTA TAKHKGRREG 1560

EELDSQGDAS SQPDTISIAS RTSQNTVDSD KLSGGCELTV VIHDFVASNG SSGELSVRRG 1620

QTVEVLERLH DKPDWCLVRT TDRSPAQEGI VPCSMLCIAH SRSSMEMEGL FNHKDTLSVS 1680

SNDGLQPGSS QTLGPHSSPG PKRPGNTLRK WLTSPVRRLS SGKADGHVKK LAHKHKKNRE 1740

GARKNMDAMH GSQKDSDDSA ATPQDETLEE RMRNEGLSSG TLSKSSSSGM QSCGEEEGEE 1800

GADAVPLPPP MAIQQHSLLQ PDSQDDKSGS RLSARPSSSE TPSAAELVSA IEELVKSKMS 1860

LEDRPSSLSV EQGDSSSPSL NPSDNSLLSS SSPMDEMDER KADFLKRRHY VLLELVETER 1920

DYVRDLGSVV EGYMCRMKEE GVPDDMRGKD KIVFGNIHQI YDWHKDFFLG ELEKCLENPD 1980

RLAPLFIKQE RRLHMYIVYC QNKPKSEHIV SEYIDTYFED LKQRLGHRLQ ITDLLIKPVQ 2040

RIMKYQLLLK DLLKMSKKAG LETAELEKAV EVMCVVPKRC NDMMNVGRLQ GFEGKIVAQG 2100

RLLLQDTFMV SDQDGGLLSR MKERRVFLFE QIVIFSEPLD KKKGFSTPGY LFKNSIKVSW 2160

LGLEEHSEDP CKFTLTSRSS SGNLERYTLH SMSPGVSQVW VLQVSQILEN QRNFLNALTS 2220

PIEYQRNHVG SGGPAALPSG SSTGGLPGGG SSTGSSSMGV GGGGGSGGPG NSSSSSLCGP 2280

RSRPSRIPQP SSRLPQPVHH HHPPGPDGPD RSAGMWSPRH QSLPSNSYSE SATNGELLGS 2340

DIPKMKRLEP HGSNSNNSNK SSESNEDTQK HTAAGIPQMV VAPLNLTLKS PRVGTVSPLI 2400

SPQSPSGGKE AFIPSSPAHK GNLFWAVVPP MPSSVPSRPS SLSYPSDSVG GGDSLGRGGH 2460

STPSHHHRHS THSKDIDRMS TCSSTSEQSV QSTQSNGSEN SSSSIVSTML VTQDYVAVKE 2520

DEISVVQGEV VQILASNQQN MFLHRAANEH SPAAEGWIPG YVLGHTSSSV TPELPEGTIK 2580

KSLSWHTALR IRRKSEKRDK EGRKMENGYR KSQDSLANKV SVKLLNPNFI PDASPEFLIP 2640

VADVACESGD TVTLRCKICS RPRATITWRG PDNSARSNNG RYSTAYSETE EATLRIVGVS 2700

AEDSGLYTCV ATNVAGSVTS SANLTVSASP DGNSEIWKSN FEFNYTEITE LGRGRFSVTK 2760

RCDQRGSKRT VAAKYVNKKL LRREQVLQEI RLLQTLDHPN LVKLLDTYEM ANSYVLVLEM 2820

ADQGRFLDYV VSWGNLTEEK VALYLREILE ALQYLHGWRV AHLDLKPENI VVEHASSQPV 2880

IKLTDFGDAV HLSPASSYIR PLLGSPEFSA PELVLGQPAS LMSDIWSLGV VTYVVLSGAS 2940

PFLDESLEET CLNICRLDFS FPEDYFQGVS LAAKDFVCLL LQSEPERRPT ASACLQELWL 3000

QPRGVINTGF LDTSRLISFI ERRKHQNDIR PIDTIAAFLH SRLLNSV 3047

Nucleotide Sequence
(FASTA)

ATGAAGGCCA TTGACGTACT TCCTATCCTC AAGGAGAAGG TTGCCTTTCT CTCAGGTGGC 60

AGAGACAGAC GTGGGGGTCC TGTTCTCACA TTTCCTGCAC GGAGCAACCA TGACAGAATA 120

CGACCTGAAG ACCTGCGCAG GCTTATCGCT TACCTGGCTA CCATTCCCAG CGAGGAGGTG 180

GCAAGGCATG GCTTCACGGT CATTGTGGAC ATGCGTGGCT CTAAATGGGA CAGCATCAAG 240

CCTTTACTGA AGATCCTTCA GGAGTCGTTT CCATCTTGCA TCCACGTCGC CCTCATCATC 300

AAGCCCGACA ACTTCTGGCA GAAGCAAAGG ACCAACTTTG GCAGCTCCAA GTTTGAATTC 360

GAGACAGTGA TGGTCTCTTT AGAGGGTTTG TCCAAAATTG TGGACCCATC ACAGCTGACG 420

GCTGACTTTG AGGGCAGCCT GGAGTACAAC CACGATGACT GGATCGAGGT GCGGCTGTCC 480

TTTGAGACCT TTGCCAGTGA TGCGGCACGT GCACTGGCAC GCCTGGAGGA GCTCCAGGAC 540

ACGTTGTCCC AGCGTGATCT CCCACGGGAC CTGGAGGGAG CTCGGCGGCT CATGGAAGAA 600

CATGCAGCAC TAAAGAAAAG GGCGACCAAA GCATCCGTGG AGGAGCTGGA CACGCAGGGA 660

CGAAGGCTGC TGCAGAGGCT GCAGGCACAG GCTTCGGGAG GAGGCAGCGT TAACGCTGAC 720

GCACACAACC TCATCGCTAA AGTGAGCGGC TTGTTGGATA AGCTTCATGG GACTCGGCAA 780

AATCTGCAGC AGCTGTGGCA CATGAGGAAG CTGAAACTGG ACCAGTGCTT CCAGCTGCGT 840

CTTTTCGAAC AGGACGCCGA GAAGATGTTC GACTGGATCA TGCACAACAA GGGGCTTTTT 900

CTCACCAGTT ACACAGAGAT TGGGGGGAAC CACCAGCATG CTGTTGAGCT GCAGACCCAG 960

CACAACCACT TTGCCATGAA CTGCATGAAC GTATATGTGA ACATTAACCG GATCATGTCA 1020

GTTGGGAACC GGCTGCTGGA GTCAGGCCAT TACGCCTCGC AGCAGATCCA GCAGATCTCT 1080

GGGCAGCTGG AGCAGGAGTG GAAGGCCTTT GCTGCGGCGC TGGATGAGCG TAGCACGCTG 1140

CTGGAGATGT CTGCCAGCTT CCACCAGAAA GCTGATCAGT ACATGAGTAA AGTGGAACCG 1200

TGGTGTAAGG CCTGTGGTGA AGGAGAGCTG CCCTCTGAAC TCCAGGATCT TGAAGACACA 1260

ATCCACCATC ATCAAGGCCT TTATGAGCAC ATCACCACCG CTTACTCTGA GGTAAGCCAG 1320

GATGGAAAGT CATTGTTGGA TAAGCTTCAG CGCCCTTTGA CCCCTGGGAG CGCTGATTCC 1380

TTAATGGCAT CGGCAAACTA CTCCAAGGCC GTGCATCACG TCTTAGACAT CATTCACGAG 1440

GTGCTGCACC ACCAGAGGCA GCTGGAAAAC ATCTGGCAGC ATCGCAAAGT TCGCCTGCAC 1500

CAACGACTGC AGCTTTGTGT TTTTCAGCAG GAGGTGCAGC AAGTACTGGA CTGGATAGAA 1560

AACCACGGGG AGGCCTTTCT TAGTAAACAC ACAGGTGTTG GCAAGTCTCT GCATAGAGCC 1620

AGAGCATTGC AGAAGAGGCA TGAGGATTTT GAAGAAGTTG CACAGAACAC CTACACTAAT 1680

GCTGACAAGC TGCTGGAAGC TGCGGAGCAG CTGGCTCAGA CCGGCGAATG TGATCCAGAG 1740

GAAATTTACC AGGCTGCCCA CCAGCTGGAA GATCGCATCC AGGACTTTGT GCGACGTGTT 1800

GAGCAGAGAA AAGTCCTCTT GGATATGTCC GTTGCTTTCC ACACGCACGT TAAAGAGCTG 1860

TGGACGTGGC TGGAGGAGTT GCAGAAGGAA TTGCTGGATG ACGTGTATGC AGAATCCGTG 1920

GAGGCGGTCC AGGACCTGAT CAAACGGTTC GGCCAGCAGC AGCAGACCAC TCTGCAGGCT 1980

ACTGTCAATG TCATCAAAGA GGGAGAGGAC CTTATCCAAC AGCTCAGAGA CTCTGCTATT 2040

TCAAGCAACA AAACGCCGCA CAACAGCTCC ATGGCCCACA TCGAAAGCGT GCTGCAGCAG 2100

CTGGACGAGG CCCAGGGCCA GATGGAGGAA CTGTTTCAAG AAAGGAAGAT CAAACTGGAG 2160

CTCTTTCTGC AGCTCCGCAT CTTTGAGAGG GACGCTATTG ATATCATCTC AGACCTAGAG 2220

TCATGGAACG AGGAGCTGTC CCAGCAGATG AGTGACTTTG ACACCGAGGA TCTGACGCTG 2280

GCCGAGCAGA GGCTGCAGCA CCACGCGGAC AAGGCGCTGA CCATGAACAA CCTGACCTAC 2340

GACGTCATCC ACCAGGGCCA GGAGCTGCTG CAGTACGTCA CCGAGGTCCA GGCGTCCGGT 2400

GTGGAGCTGT TGTGCGACAG AGATGTGGAC ATGGCCACGC GAGTGCAGGA CCTGCTGGAG 2460

TTCCTCCATG AGAAGCAGCA GGAGCTGGAC CTGGCGGCAG AGCAGCACAG GAGACACCTG 2520

GAGCAGTGTG TCCAACTGAG ACATCTCCAG GCAGAAGTCA AGCAGGTGCT GGGATGGATC 2580

CGTAATGGCG AGTCCATGCT GAATGCCGGT CTGATCACAG CCAGCTCGTT ACAGGAAGCT 2640

GAACAGCTGC AGAAGGAACA TGAACAATTT CAGCATGCAA TAGAGGAAAA CACAAGCTCC 2700

TTTCAGGTTT ACAAATTTGT ACTTCCCCTC TTCTCACAAT TAGCACATGA AATGGAATTA 2760

TTTTTAACCC TATATCCTAA GGTGGCAGAC CACTGGCAGC AGCTCATGCT GAAGATGGAG 2820

GACCGGCTCA AGCTGGTCAA CGCTTCTGTG GCTTTCTACA AAACCTCCGA ACAGGTTTGT 2880

AGCGTGTTAG AAAGCCTGGA GCAGGAGTAC AAGAGAGAAG AGGACTGGTG TGGCGGCGCT 2940

GATAAACTAG GCCCGAACAG CGAGTCAGAC CACGTCACTC CCATGATTAG TAAACACCTA 3000

GAGCAGAAAG AGGCCTTCCT TAAGGCATGC ACATTAGCCA GGCGGAATGC TGACGTCTTC 3060

TTGAAGTACC TGCACAGAAA CAGCGTCAAT ATGCCCGGCA TGCTGTCCCA TATCAAAGCC 3120

CCAGAGACTC AGGTTAAGAA TATCTTGAAT GAGCTGCTCC AGAGAGAAAA CAGAGTCCTT 3180

CACTTCTGGA CAATGAGGAA GAGGAGGCTC GACCAGTGTC AGCAATATGT CGTATTTGAA 3240

CGCAGTGCCA AACAGGCCCT GGAGTGGATA CATGACACAG GAGAGTTTTA CTTGTCCACA 3300

CACACATCCA CCGGTTCCAG CATTCATCAC ACACAGGAGC TCCTGAAGGA GCACGAGGAC 3360

TTCCAGATCA CAGCAAAACA AACCAAAGAG CGGGTAAAGC TGTTGATCCA GCTGGCAGAT 3420

GGGTTTTGTG ACAAGGGGCA CGCCCATGCT CTGGAAATAA AGAAATGGGT GTCTTCTGTG 3480

GACAAGCGCT ACCGGGACTT CTCTCTCCGC ATGGACAAAT ACCGAACCTC CCTGGAAACG 3540

GCGCTCGGCA TATCATCCGA CTCCAACAAG GCTAGTAAAG AGCTCCAGCT GGACATAATC 3600

CCAGCCAGTG CTCCGGGCTC AGAGGTCAAA CTCCGGGATG CTGCCCATGA GCTCAACGAG 3660

GAGAAGAGGA AATCGGCACG GAGGAAGGAA TTCATAATGG CCGAGCTGAT TCAGACAGAG 3720

AAGGCCTACG TCAGGGACCT ACGAGAGTGT CTAGATACGT ACCTGTGGGA GATGACCAGT 3780

GGCGTGGAGG AGATTCCCGC CGGAATTGTC AACAAGGAGC ACATTATCTT TGGCAATATG 3840

CAGGACCTCT ACGAGTTCCA CCACAACATC TTCCTGAAGG AGTTGGAGAA GTATGAGCAA 3900

CTTCCAGAAG ACGTTGGCCA TTGTTTTGTC ACTTGGGCTG ACAAGTTCCA GATGTACGTC 3960

AGTTACTGTA AGAACAAACC CGATTCCACG CAGCTCATTC TCGAACATGC CGGAGCATAC 4020

TTTGATGAAA TCCAGCAAAG ACATCGCCTT GCGAACTCTA TCTCCTCCTA CCTGATCAAA 4080

CCAGTGCAGA GAATCACAAA GTACCAGCTG CTTCTCAAAG AGTTGTTGAC ATGCTGTGAG 4140

GAAGGTAAAG GTGAGATCAA GGACGGCCTG GAAGTGATGC TTAGCGTTCC GAAGAAAGCC 4200

AACGACGCCA TGCACCTGTC TATGCTGGAG GGATTTGATG GAAACATAGA CTCCCAGGGA 4260

GAGCTGATAC TGCAGGAATC CTTCCAGGTC TGGGATCCCA AGACTCTGAT CCGAAAGGGT 4320

CGTGACCGAC ACCTCTTCCT GTTTGAGATG TCCCTGGTCT TTAGCAAAGA AGTCAAAGAT 4380

TCCAATGGGC GTAGCAAATA CCTCTACAAG AGCAAGCTCT TCACATCAGA ACTTGGAGTT 4440

ACGGAACATG TGGAGGGGGA TCCCTGTAAG TTCGCCCGTG CCACTGATCC TGTAAACGAA 4500

TCCCCTCTGA CCCGTCGACG TGTTCTGCCT CAGGCTTCCA GTATCGAGAA CAAACAGGAC 4560

TGGATCAAAC ACATCCGAGA GGTGATCCAG GAGCGCACCG TCCACCTGCG CGGAGCTCTG 4620

AAGGAGCCCA TCCACATCCC CAAAACCGCC ACAGCCAAAC ACAAAGGCAG ACGGGAGGGA 4680

GAAGAGCTGG ACAGCCAGGG GGATGCCAGC AGCCAACCTG ACACCATCTC CATTGCTTCA 4740

CGCACATCCC AAAACACAGT GGACAGCGAT AAGCTTTCCG GTGGCTGTGA ATTGACAGTG 4800

GTGATCCACG ACTTCGTAGC CAGTAATGGC AGCAGCGGTG AGCTGTCGGT GCGTCGAGGT 4860

CAGACTGTGG AGGTCCTGGA GCGGCTCCAC GACAAGCCTG ACTGGTGCCT GGTGCGGACC 4920

ACGGACCGTT CTCCAGCTCA GGAGGGCATT GTTCCCTGCT CCATGCTCTG CATCGCTCAC 4980

TCAAGGTCGT CCATGGAGAT GGAGGGGCTC TTTAACCACA AAGACACGTT ATCTGTATCC 5040

AGTAATGATG GCCTACAACC AGGCTCCAGC CAAACCCTGG GTCCGCACAG CTCCCCCGGC 5100

CCCAAACGCC CAGGGAACAC GCTGAGGAAG TGGCTGACCA GCCCCGTGCG GAGGCTCAGC 5160

TCTGGCAAAG CCGACGGCCA CGTGAAGAAA CTGGCCCACA AGCACAAGAA GAACCGCGAG 5220

GGAGCGAGAA AGAACATGGA CGCCATGCAC GGCTCTCAGA AAGACTCTGA TGACAGCGCT 5280

GCTACACCCC AGGATGAGAC GCTGGAGGAG CGTATGCGTA ACGAAGGCCT GAGCAGCGGC 5340

ACCCTGTCCA AGTCTTCCTC TTCTGGCATG CAGAGCTGTG GCGAGGAGGA AGGAGAGGAG 5400

GGAGCTGACG CTGTCCCTCT ACCGCCCCCT ATGGCCATCC AGCAGCACAG CCTGCTGCAG 5460

CCTGACTCCC AGGATGACAA GTCCGGATCT CGTTTGTCTG CTCGTCCGAG CAGTTCAGAG 5520

ACTCCCAGCG CTGCCGAATT GGTCAGCGCC ATTGAAGAGC TGGTAAAGAG TAAGATGTCC 5580

CTAGAGGATC GTCCCAGCTC TCTGTCTGTA GAACAAGGCG ATAGCAGCTC TCCATCCCTA 5640

AATCCCTCTG ACAACTCCCT CCTCTCCTCC TCCTCACCCA TGGACGAGAT GGACGAGCGC 5700

AAGGCCGACT TCCTCAAAAG AAGACATTAC GTGCTTCTGG AGCTGGTGGA GACCGAGAGG 5760

GATTACGTCA GAGATCTCGG ATCAGTGGTG GAGGGCTACA TGTGCAGGAT GAAAGAAGAG 5820

GGCGTTCCCG ACGACATGAG GGGAAAAGAT AAGATCGTCT TTGGGAATAT CCATCAGATC 5880

TACGACTGGC ACAAAGATTT TTTCCTGGGG GAGCTTGAGA AGTGTTTAGA GAATCCTGAC 5940

AGACTGGCTC CGTTATTCAT CAAACAGGAG CGGAGGCTGC ACATGTACAT CGTGTACTGC 6000

CAGAACAAAC CCAAGTCTGA GCACATCGTT TCAGAATACA TTGACACTTA TTTTGAGGAC 6060

TTAAAGCAGC GTTTGGGCCA CAGGCTGCAG ATCACCGACC TGCTAATTAA GCCTGTCCAG 6120

CGTATAATGA AGTACCAATT ACTGCTAAAA GATCTTCTAA AAATGTCCAA GAAGGCTGGC 6180

TTGGAAACAG CAGAGCTTGA GAAAGCTGTG GAGGTGATGT GTGTGGTTCC CAAACGCTGC 6240

AACGACATGA TGAATGTTGG ACGCCTTCAG GGCTTTGAAG GTAAAATTGT GGCACAGGGC 6300

AGATTGCTGC TCCAAGATAC CTTTATGGTG TCCGACCAGG ATGGAGGACT TCTGTCCAGG 6360

ATGAAGGAGA GAAGAGTGTT CCTGTTTGAA CAGATAGTTA TATTTAGCGA ACCTCTTGAC 6420

AAAAAGAAGG GCTTCTCCAC TCCAGGATAC CTCTTTAAGA ACAGCATCAA GGTGAGCTGG 6480

TTGGGCTTAG AAGAACATTC AGAAGATCCG TGCAAGTTCA CACTTACCTC CAGATCATCT 6540

AGTGGCAACT TAGAGAGATA CACCCTTCAT TCAATGAGTC CCGGAGTCAG TCAAGTCTGG 6600

GTGCTCCAGG TTAGCCAGAT ATTGGAGAAC CAGCGCAATT TCCTCAACGC TCTGACGTCT 6660

CCTATTGAGT ACCAGAGAAA CCATGTGGGG AGTGGAGGGC CAGCTGCTCT CCCCAGCGGC 6720

AGCAGTACTG GAGGCCTTCC AGGAGGCGGG AGCTCCACTG GGTCCTCTAG CATGGGAGTG 6780

GGTGGCGGCG GTGGCTCTGG GGGACCGGGG AACAGCTCAT CCTCCTCTCT TTGCGGTCCC 6840

CGTTCCCGGC CATCCCGCAT TCCACAGCCA TCATCACGGC TCCCACAACC CGTCCACCAC 6900

CACCATCCCC CGGGCCCTGA TGGGCCCGAC CGCTCAGCAG GTATGTGGTC ACCCCGCCAT 6960

CAGTCCCTCC CATCTAACTC TTATTCAGAG AGTGCCACAA ATGGAGAACT GTTAGGCTCA 7020

GACATCCCCA AGATGAAAAG ACTGGAGCCT CACGGAAGTA ACAGTAACAA CAGTAACAAG 7080

TCCTCAGAAA GCAACGAAGA CACTCAGAAA CACACAGCAG CTGGGATACC GCAGATGGTG 7140

GTTGCACCTC TGAACCTGAC ACTAAAAAGC CCTCGAGTTG GGACAGTTTC TCCTCTGATT 7200

TCACCTCAGT CTCCTTCAGG AGGAAAAGAA GCATTTATCC CCTCAAGTCC AGCTCATAAA 7260

GGCAACTTGT TCTGGGCTGT GGTCCCTCCT ATGCCTTCCT CTGTGCCGAG CCGGCCCAGT 7320

TCTCTCTCGT ACCCTAGCGA TAGTGTTGGT GGAGGGGATT CTTTGGGCCG AGGGGGGCAC 7380

AGTACACCCT CCCACCACCA TCGCCACTCC ACCCACAGTA AGGACATAGA CCGCATGAGC 7440

ACCTGCTCCT CCACCAGCGA GCAGTCCGTA CAGTCAACAC AGAGCAATGG GAGTGAAAAC 7500

AGTAGCAGCA GCATTGTGTC CACCATGTTG GTGACCCAGG ACTATGTGGC AGTGAAGGAG 7560

GATGAGATCA GTGTGGTGCA GGGTGAGGTG GTCCAAATAC TAGCCAGCAA CCAACAAAAC 7620

ATGTTCCTTC ACCGGGCAGC CAACGAGCAC TCTCCTGCTG CAGAGGGCTG GATCCCTGGC 7680

TATGTATTAG GACACACCTC ATCTTCTGTC ACACCTGAGC TCCCTGAAGG AACCATCAAA 7740

AAATCACTTT CATGGCACAC AGCACTTCGA ATTCGCCGGA AATCTGAAAA AAGGGACAAA 7800

GAGGGCAGAA AGATGGAAAA TGGTTACCGC AAATCTCAGG ACAGCCTGGC CAACAAAGTC 7860

TCTGTTAAGC TTCTGAATCC CAATTTCATT CCCGATGCTT CTCCAGAATT CCTCATCCCT 7920

GTCGCCGATG TAGCATGTGA GAGCGGCGAC ACTGTGACTC TGAGGTGTAA AATTTGTAGC 7980

CGGCCTCGCG CCACCATTAC CTGGCGAGGA CCTGACAACA GTGCCAGAAG CAACAACGGA 8040

CGCTACAGCA CCGCTTACAG TGAGACAGAA GAAGCAACTC TGCGTATTGT GGGGGTGTCT 8100

GCAGAGGACA GTGGCCTGTA CACCTGTGTC GCCACAAATG TTGCGGGCTC TGTCACGTCC 8160

TCCGCCAACC TCACAGTCTC AGCATCGCCT GATGGCAACA GTGAGATCTG GAAAAGCAAC 8220

TTTGAGTTCA ACTACACAGA GATCACGGAA CTAGGAAGGG GCCGCTTCTC GGTGACTAAA 8280

CGGTGCGACC AGAGAGGGAG CAAGCGCACA GTTGCGGCCA AATACGTTAA CAAGAAGCTG 8340

CTGCGCCGAG AACAGGTGCT GCAGGAGATC CGACTCCTGC AGACTCTGGA CCATCCCAAC 8400

CTGGTTAAGC TGCTGGACAC CTACGAGATG GCCAACAGCT ACGTACTTGT ACTGGAAATG 8460

GCAGACCAGG GGCGATTCTT GGATTATGTA GTGAGCTGGG GCAACCTGAC AGAGGAAAAA 8520

GTGGCACTGT ACCTCAGAGA AATTCTTGAA GCTCTTCAGT ACCTGCACGG ATGGCGGGTA 8580

GCGCACCTCG ACCTCAAACC CGAGAACATT GTGGTAGAAC ATGCGTCCTC GCAGCCGGTG 8640

ATCAAGCTGA CGGACTTCGG TGATGCTGTG CACCTGAGCC CTGCCTCCTC CTACATCCGT 8700

CCTCTGCTGG GGAGCCCAGA GTTCTCAGCT CCTGAGCTGG TCCTCGGGCA GCCCGCCTCG 8760

CTGATGTCCG ACATCTGGAG TTTAGGGGTA GTGACATATG TTGTCCTGAG TGGCGCTTCT 8820

CCCTTCCTGG ATGAGAGCTT GGAGGAGACA TGTCTGAACA TCTGTCGCCT GGACTTCAGC 8880

TTCCCGGAGG ACTACTTCCA GGGAGTGAGC CTGGCTGCCA AGGACTTCGT CTGCCTGCTG 8940

CTCCAGAGCG AGCCAGAGCG ACGGCCCACT GCGTCAGCCT GCCTGCAGGA GCTGTGGCTC 9000

CAGCCTCGAG GTGTAATCAA CACAGGATTC CTGGACACAT CCAGACTGAT TTCCTTCATT 9060

GAGAGGCGGA AACACCAGAA CGACATCCGG CCCATAGACA CGATCGCGGC CTTCCTCCAC 9120

AGCCGCCTGC TAAACAGCGT CTGA 9144

Domain Profile

S: 1     yevleeigRGrFsvvkkvrekatkravaakfvpkkakkkaqvlrEaeiLkrLqHpllvsl  60

         y++ +e+gRGrFsv k+++++++kr+vaak+v+kk  +++qvl+E ++L++L Hp+lv+l

Q: 2745  YTEITELGRGRFSVTKRCDQRGSKRTVAAKYVNKKLLRREQVLQEIRLLQTLDHPNLVKL  2804

         8999********************************************************

S: 61    hdayetprslvlilElcsdeeLLdrlaekeslsEsevkaylrqllealqYLHnsrvlHLD  120

         +d+ye  +s+vl+lE++++++ Ld+++++++l+E++v+ ylr++lealqYLH  rv+HLD

Q: 2805  LDTYEMANSYVLVLEMADQGRFLDYVVSWGNLTEEKVALYLREILEALQYLHGWRVAHLD  2864

         ************************************************************

S: 121   ikpenllv.laaaeeavkivDlgnAqeltpee.pqekllgtpEfvaPEiiegepvseatD  178

         +kpen++v +a +++ +k+ D+g+A++l+p++ ++  llg+pEf aPE++ g+p+s  +D

Q: 2865  LKPENIVVeHASSQPVIKLTDFGDAVHLSPASsYIRPLLGSPEFSAPELVLGQPASLMSD  2924

         ********66778899**************99899*************************

S: 179   iWavGvlayvlLsgvsPfldeskretllnilkgrvsfseelfaglseeAkeFlkkvLqed  238

         iW++Gv++yv+Lsg sPfldes +et+lni+++++sf+e++f+g+s +Ak+F++ +Lq++

Q: 2925  IWSLGVVTYVVLSGASPFLDESLEETCLNICRLDFSFPEDYFQGVSLAAKDFVCLLLQSE  2984

         ************************************************************

S: 239   prkRPsaaecLqhpWl  254

         p +RP+a+ cLq+ Wl

Q: 2985  PERRPTASACLQELWL  3000

         ***************8

Domain Sequence
(FASTA)

YTEITELGRG RFSVTKRCDQ RGSKRTVAAK YVNKKLLRRE QVLQEIRLLQ TLDHPNLVKL 60

LDTYEMANSY VLVLEMADQG RFLDYVVSWG NLTEEKVALY LREILEALQY LHGWRVAHLD 120

LKPENIVVEH ASSQPVIKLT DFGDAVHLSP ASSYIRPLLG SPEFSAPELV LGQPASLMSD 180

IWSLGVVTYV VLSGASPFLD ESLEETCLNI CRLDFSFPED YFQGVSLAAK DFVCLLLQSE 240

PERRPTASAC LQELWL 256

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Repeat; SH3 domain; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0005524	; F:ATP binding
GO:0005543	; F:phospholipid binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0005089	; F:Rho guanyl-nucleotide exchange factor activity
GO:0035023	; P:regulation of Rho protein signal transduction

KEGG

InterPros

IPR001251	; CRAL-TRIO_dom.
IPR000219	; DH-domain.
IPR007110	; Ig-like.
IPR013783	; Ig-like_fold.
IPR013098	; Ig_I-set.
IPR003598	; Ig_sub2.
IPR011009	; Kinase-like_dom.
IPR011993	; PH_like_dom.
IPR001849	; Pleckstrin_homology.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR001452	; SH3_domain.
IPR018159	; Spectrin/alpha-actinin.
IPR002017	; Spectrin_repeat.

Pfam

PF07679	; I-set; 1.
PF00069	; Pkinase; 1.
PF00621	; RhoGEF; 2.
PF00018	; SH3_1; 1.
PF00435	; Spectrin; 3.

SMARTs

SM00408	; IGc2; 1.
SM00233	; PH; 2.
SM00325	; RhoGEF; 2.
SM00220	; S_TKc; 1.
SM00516	; SEC14; 1.
SM00326	; SH3; 2.
SM00150	; SPEC; 6.

Prosites

PS50191	; CRAL_TRIO; 1.
PS50010	; DH_2; 2.
PS50835	; IG_LIKE; 1.
PS50003	; PH_DOMAIN; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50002	; SH3; 1.

Prints

Created Date

20-Feb-2013