EKS-TEN-00261

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TEN-00261

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	515.7	2.6E-155	4	287	284

Status

Unreviewed

Ensembl Protein

ENSTNIP00000022539

UniProt Accession

H3DPU0;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL1

Gene Synonyms/Alias

CDKL1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTNIG00000019336	ENSTNIP00000022539	ENSTNIT00000022778

Organism

Tetraodon nigroviridis

Functional Description

Protein Length

349

Protein Sequence
(FASTA)

MEKYEKIGKI GEGSYGVVFK CRNRDTGQIV AIKKFVESED DPVIKKIALR EIRMLKQLKH 60

ANLVNLIEVF RRKRKLHLVF EYCDHTVLNE LDRHPRGVPE ALVRSITRQT LQAVNFCHKQ 120

SCIHRDVKPE NILITKQQVI KLCDFGFARI LTGPCDYYTD YVATRWYRAP ELLVGDTQYG 180

PPVDVWAIGC VFAELLSGVP LWPGKSDMDQ LYLIRKTLGD LTPRHQQVFS SNQFFCGVSI 240

PEPQEREPLE QKYPGISSQA LSLMKGCLRM DPSERLTCEQ LLLHPYFDSL REKSESSSRE 300

QDRNRRTRFP RKHLPPAQYL PQLTSSSVFP AVDNRRSNLR KFNYHLPNI 349

Nucleotide Sequence
(FASTA)

ATGGAGAAAT ACGAGAAGAT CGGGAAGATC GGCGAGGGCT CCTACGGGGT GGTGTTCAAG 60

TGCAGGAACA GGGACACGGG CCAGATCGTC GCCATCAAGA AGTTCGTGGA GTCCGAAGAC 120

GACCCCGTCA TCAAAAAGAT CGCGCTGAGG GAGATCCGGA TGCTCAAGCA ACTCAAACAC 180

GCCAACCTGG TGAACCTGAT CGAGGTGTTC CGGCGCAAAC GAAAGCTGCA CCTGGTGTTC 240

GAGTACTGCG ACCACACGGT CCTCAACGAG CTGGACCGCC ATCCCAGAGG GGTTCCAGAG 300

GCCCTGGTCC GAAGTATAAC CCGGCAGACT CTTCAGGCCG TCAACTTCTG TCACAAACAG 360

AGCTGCATCC ACCGGGACGT CAAACCCGAG AACATCCTCA TCACCAAACA GCAGGTCATC 420

AAACTCTGCG ACTTCGGCTT CGCCAGGATT CTCACCGGAC CGTGCGACTA CTACACCGAC 480

TACGTGGCGA CGCGCTGGTA TCGGGCCCCC GAGCTGCTGG TGGGGGACAC TCAGTACGGC 540

CCTCCGGTGG ACGTGTGGGC CATCGGATGC GTGTTTGCGG AGCTGCTGTC GGGGGTTCCT 600

CTGTGGCCCG GGAAGTCGGA CATGGACCAG CTGTACCTGA TCCGAAAGAC TCTGGGAGAT 660

CTGACCCCTC GCCATCAGCA GGTCTTCAGC AGCAACCAGT TCTTCTGTGG CGTCTCCATC 720

CCAGAACCTC AGGAGAGGGA GCCTCTGGAG CAGAAATACC CAGGTATCTC CAGCCAGGCT 780

CTGAGTCTCA TGAAGGGTTG TCTGCGGATG GACCCGTCGG AGCGGCTGAC CTGCGAGCAG 840

CTGCTGCTGC ATCCCTACTT TGACAGCCTG CGGGAAAAGA GCGAGAGCAG CTCCCGGGAG 900

CAGGACCGCA ACAGGAGGAC ACGTTTTCCC CGGAAGCACC TCCCCCCCGC CCAGTATCTC 960

CCCCAGCTGA CCAGCAGCAG CGTCTTCCCG GCCGTGGACA ACCGGAGGTC CAACCTGCGC 1020

AAGTTCAACT ACCACCTCCC CAACATCTGA 1050

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yek+gk+GeGsyGvv+kcrn+dtgqivaikkf+esedd+++kkialrei++lkqlkh nl

Q: 4     YEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFVESEDDPVIKKIALREIRMLKQLKHANL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfrrk+kl+lvfey+d+tvl+el+r+p+Gv+e lv++i+ q+l+a++fchk+ +i

Q: 64    VNLIEVFRRKRKLHLVFEYCDHTVLNELDRHPRGVPEALVRSITRQTLQAVNFCHKQSCI  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenili+k++v+klcdfGfar+l++p d+ytdyvatrwyrapellvgdt+yG++v

Q: 124   HRDVKPENILITKQQVIKLCDFGFARILTGPCDYYTDYVATRWYRAPELLVGDTQYGPPV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGc++aell+G pl+pgksd+dqly+irktlG+l+prhq++fs+n++f Gv++pe+

Q: 184   DVWAIGCVFAELLSGVPLWPGKSDMDQLYLIRKTLGDLTPRHQQVFSSNQFFCGVSIPEP  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++e+le+kyp +++ +l+l+k+cl++dp+erl+ce+ll h+yf

Q: 244   QEREPLEQKYPGISSQALSLMKGCLRMDPSERLTCEQLLLHPYF  287

         *******************************************9

Domain Sequence
(FASTA)

YEKIGKIGEG SYGVVFKCRN RDTGQIVAIK KFVESEDDPV IKKIALREIR MLKQLKHANL 60

VNLIEVFRRK RKLHLVFEYC DHTVLNELDR HPRGVPEALV RSITRQTLQA VNFCHKQSCI 120

HRDVKPENIL ITKQQVIKLC DFGFARILTG PCDYYTDYVA TRWYRAPELL VGDTQYGPPV 180

DVWAIGCVFA ELLSGVPLWP GKSDMDQLYL IRKTLGDLTP RHQQVFSSNQ FFCGVSIPEP 240

QEREPLEQKY PGISSQALSL MKGCLRMDPS ERLTCEQLLL HPYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013