EKS-TAR-00376

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00376

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	464.0	3.3E-139	577	838	262

Status

Unreviewed

Ensembl Protein

ENSTRUP00000002435

UniProt Accession

H2RQM0;

Protein Name

Protein Synonyms/Alias

Gene Name

ERN1 (1 of 3)

Gene Synonyms/Alias

ERN1 (1 of 3);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000001041	ENSTRUP00000002435	ENSTRUT00000002447
ENSTRUG00000001041	ENSTRUP00000002434	ENSTRUT00000002446
ENSTRUG00000001041	ENSTRUP00000002437	ENSTRUT00000002449
ENSTRUG00000001041	ENSTRUP00000002436	ENSTRUT00000002448

Organism

Takifugu rubripes

Functional Description

Protein Length

983

Protein Sequence
(FASTA)

VTLNSLKLLL SCLFNHHPPP SFSGLCSATT VSLPESLLFV STLDGNLHAV SKKSGSIKWT 60

LKEDPVLQVP THVAEPAFLP DPNDGSLYSL GGKNSEGLTK LPFTIPELVQ ASPCRSSDGV 120

LYMGKKQDLW YVVDLLTGEK QQTLTSSFAE MLCPSSSLLY LGRTEYTITM YDTKSRELRW 180

NATYSDYAST LPDDDTKYKM AHFASNGDGL VVTVDSDSGD VQWVQNYNSP VVAIYIWQRE 240

GLRKVAHTNV AVETLRYLTF MSGEVGRITQ WKYPFPKEKK PKNKFLATLY VGKYSTSLYA 300

SPSLVHDGVT VVTQPRGSTF PMLGGPDSQE TEEDKECVIT PSTSVKFNAA LRKRNRVNFM 360

SNYLLLIGHH ETPPEAHTKI LEKFPDSFPR AQGNIIPPTT DKKAEEKVND SGMDDAPPPP 420

LPDTSIQEPG TAGRSVRPEA PVDSMLKDMA TIIFSTFLLA GWVAFVITYP KLPQSVHKQQ 480

QLQHQEFQRQ MEERLELLQR QQPFLSADIG LGLGQDSDYL EVVRARSESS DHSSPNVTPR 540

ASNHSNLSVS EHGSSPYEHE EGAEEESSVV RVGNVSFRPK EVLGHGAEGT IVYKGQFDNR 600

AVAVKRILPE CFSFADREVQ LLRESDEHPN VIRYFCTERD RQFQYIAIEL CAASLQEYVE 660

RKDFERRGLE PVMLLQQTMS GLAHLHSLNI VHRDLKPHNI LVSMPNAHGR VRAMISDFGL 720

CKKLAVGRHS FSRRSGVPGT EGWIAPEVLS EDCKDNPTCA VDIFSAGCVF YYVVSQGSHP 780

FGKSLQRQAN ILLGTYSLDY LQTDKHGDIV ARDLIEQMLS VEPYKRPSAE SLLKHPFFWS 840

LEKELQFFQD VSDRIEKEPL DGPIVRQLER GGRAVVKGDW REHITVPLQT DLRKFRSYKG 900

GSVRDLLRAM RNKKHHYREL PADVQETLGS IPDDFVSYFT SRFPHLLLHT YLAMRSCASE 960

RPFLPYYSHT PTSPSQPQDP THC 983

Nucleotide Sequence
(FASTA)

GTCACGTTAA ACTCTTTAAA GCTCCTTCTC TCTTGCCTGT TTAATCACCA CCCCCCTCCA 60

TCCTTTTCGG GCCTCTGCAG CGCCACCACT GTCTCCCTCC CCGAAAGCTT GCTGTTTGTG 120

TCCACCCTGG ACGGGAACCT ACATGCCGTC AGCAAGAAGT CGGGCTCCAT CAAATGGACC 180

CTTAAAGAAG ATCCAGTTCT TCAGGTCCCC ACACATGTGG CCGAACCGGC GTTCCTCCCT 240

GACCCCAATG ATGGCAGCCT GTACTCTCTG GGAGGAAAGA ACAGCGAAGG CCTCACAAAA 300

TTGCCGTTCA CCATCCCTGA GCTGGTGCAA GCGTCTCCCT GTCGCAGCTC CGACGGCGTT 360

CTTTACATGG GCAAGAAGCA GGACCTGTGG TACGTCGTGG ATCTGCTGAC TGGCGAGAAA 420

CAGCAGACCC TGACCTCCTC CTTCGCCGAG ATGCTGTGTC CGTCCTCCTC CCTCCTCTAC 480

CTGGGACGCA CAGAATACAC CATCACCATG TACGACACAA AGAGCAGAGA GCTGCGCTGG 540

AATGCCACCT ACTCCGACTA CGCCTCCACC CTTCCCGATG ATGACACCAA ATACAAGATG 600

GCTCATTTTG CCTCCAATGG CGACGGCCTG GTGGTGACGG TGGACAGCGA CTCCGGAGAC 660

GTTCAGTGGG TGCAGAACTA CAATTCCCCC GTGGTGGCCA TTTATATCTG GCAGCGCGAG 720

GGCCTCCGCA AAGTTGCCCA CACCAACGTG GCCGTGGAAA CCCTGCGCTA CCTCACCTTC 780

ATGTCTGGAG AGGTCGGCCG CATCACGCAG TGGAAATACC CGTTTCCCAA AGAGAAGAAA 840

CCCAAAAACA AGTTCCTGGC TACTCTCTAT GTGGGGAAAT ATTCCACCAG TCTGTATGCA 900

TCCCCCTCAT TGGTGCATGA CGGCGTCACC GTGGTGACGC AGCCTCGCGG CAGCACCTTC 960

CCCATGCTGG GGGGTCCGGA CAGCCAGGAG ACCGAAGAGG ACAAAGAGTG TGTCATCACC 1020

CCCAGCACCA GTGTCAAGTT CAATGCTGCA CTCAGAAAAA GAAATCGGGT CAACTTCATG 1080

AGCAACTATC TGCTCCTCAT CGGTCATCAT GAGACACCTC CTGAGGCTCA CACCAAGATC 1140

CTGGAGAAGT TCCCTGACAG TTTTCCTCGT GCTCAAGGCA ATATCATCCC ACCTACAACA 1200

GACAAGAAGG CAGAAGAGAA GGTGAACGAT AGCGGCATGG ATGATGCCCC GCCGCCTCCC 1260

CTGCCTGACA CGTCTATCCA GGAACCCGGG ACTGCTGGCC GAAGCGTGCG TCCGGAGGCT 1320

CCCGTTGACA GTATGCTGAA GGACATGGCC ACCATCATCT TCTCCACTTT CCTCCTGGCT 1380

GGCTGGGTGG CCTTTGTCAT TACCTACCCC AAACTGCCAC AGAGTGTTCA CAAGCAGCAA 1440

CAGCTGCAGC ATCAGGAATT CCAGAGGCAG ATGGAGGAGA GGCTGGAGCT GCTCCAGAGA 1500

CAGCAGCCAT TCCTCTCTGC AGACATTGGT TTGGGTTTAG GCCAAGACAG CGACTATCTG 1560

GAGGTGGTGC GCGCTCGTTC TGAAAGTTCA GACCACAGCA GCCCAAACGT CACCCCCCGC 1620

GCCTCCAACC ACTCCAACCT CTCCGTGTCG GAGCACGGAA GCTCTCCTTA CGAGCATGAG 1680

GAAGGAGCAG AGGAAGAATC AAGTGTTGTC CGAGTGGGAA ACGTATCATT CCGTCCTAAA 1740

GAGGTGTTGG GTCACGGCGC CGAGGGCACC ATAGTGTACA AGGGGCAGTT TGACAACCGT 1800

GCAGTGGCGG TGAAAAGGAT CCTCCCAGAG TGCTTCAGCT TCGCCGATCG GGAAGTCCAG 1860

CTGCTGAGAG AGTCAGACGA ACACCCGAAC GTCATTCGCT ACTTCTGCAC AGAGAGGGAC 1920

CGACAGTTCC AGTACATCGC CATCGAGCTG TGTGCAGCCT CGCTGCAGGA GTATGTAGAA 1980

AGGAAGGACT TTGAGCGTCG CGGGCTAGAA CCGGTGATGC TTCTTCAACA GACCATGTCA 2040

GGACTGGCCC ATCTGCACTC TCTTAACATA GTCCACAGAG ACCTGAAGCC CCACAACATA 2100

CTGGTCTCGA TGCCCAACGC TCACGGTCGG GTTCGGGCCA TGATCTCCGA CTTTGGCTTG 2160

TGTAAGAAGT TGGCAGTGGG CCGTCACAGT TTCAGTAGAA GGTCTGGGGT TCCAGGCACC 2220

GAGGGCTGGA TCGCTCCTGA GGTTCTCAGC GAGGACTGCA AAGACAACCC GACCTGCGCC 2280

GTCGACATCT TCTCTGCCGG TTGTGTGTTT TATTACGTGG TGTCCCAGGG AAGCCACCCT 2340

TTTGGGAAGT CCCTGCAGAG ACAGGCCAAC ATCTTGCTGG GAACGTACAG CCTCGACTAC 2400

CTACAAACGG ACAAACATGG AGACATTGTA GCCAGAGATC TAATAGAGCA GATGTTGAGC 2460

GTGGAACCAT ACAAGCGACC CTCAGCCGAG AGTCTTCTCA AACATCCATT CTTCTGGAGC 2520

TTGGAGAAGG AGCTGCAGTT CTTTCAGGAC GTGAGCGACA GGATCGAAAA GGAACCGCTG 2580

GACGGACCGA TTGTTAGACA GCTGGAGAGA GGAGGGAGGG CCGTTGTCAA GGGCGACTGG 2640

AGGGAACACA TCACTGTGCC ACTGCAGACA GACTTGAGGA AGTTTCGCTC CTACAAAGGC 2700

GGGTCGGTCA GAGACCTGCT GCGTGCGATG AGAAACAAGA AGCATCATTA CCGAGAGCTG 2760

CCTGCTGATG TCCAGGAGAC TCTGGGCTCC ATCCCCGATG ACTTTGTCTC CTACTTCACC 2820

TCCCGCTTCC CTCACCTGTT GCTGCACACC TACCTGGCCA TGAGGAGCTG TGCATCTGAA 2880

AGACCCTTCC TGCCTTATTA CTCTCACACG CCCACATCCC CCTCACAACC CCAGGACCCA 2940

ACACACTGT 2949

Domain Profile

S: 1     fspkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfc  60

         f pk+vlG+GaeGt+v++G+f++r+vavkr+l+e++++a+rev+llresdehpnviryfc

Q: 577   FRPKEVLGHGAEGTIVYKGQFDNRAVAVKRILPECFSFADREVQLLRESDEHPNVIRYFC  636

         679*********************************************************

S: 61    tekdrqfryialelcaaslqdyvedkdlelqkelepisllkqiasGlahlhslkivhrdl  120

         te+drqf+yia+elcaaslq+yve kd+e + +lep+ ll+q++sGlahlhsl+ivhrdl

Q: 637   TERDRQFQYIAIELCAASLQEYVERKDFE-RRGLEPVMLLQQTMSGLAHLHSLNIVHRDL  695

         *****************************.99****************************

S: 121   kpqnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltke  180

         kp+nil+s+p+a+g++r++isdfGlckkl+vG++sfsrrsgv+GteGwiape+l+e++k+

Q: 696   KPHNILVSMPNAHGRVRAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEVLSEDCKD  755

         ************************************************************

S: 181   rltsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedli  240

         ++t avdifs+Gcvfyyv+s+G+hpfG+sl+rqanil g++sld l+++k+ +++a+dli

Q: 756   NPTCAVDIFSAGCVFYYVVSQGSHPFGKSLQRQANILLGTYSLDYLQTDKHGDIVARDLI  815

         ************************************************************

S: 241   skmidkdplkrpsakkvlkhplf  263

         ++m++++p krpsa+ +lkhp+f

Q: 816   EQMLSVEPYKRPSAESLLKHPFF  838

         **********************9

Domain Sequence
(FASTA)

FRPKEVLGHG AEGTIVYKGQ FDNRAVAVKR ILPECFSFAD REVQLLRESD EHPNVIRYFC 60

TERDRQFQYI AIELCAASLQ EYVERKDFER RGLEPVMLLQ QTMSGLAHLH SLNIVHRDLK 120

PHNILVSMPN AHGRVRAMIS DFGLCKKLAV GRHSFSRRSG VPGTEGWIAP EVLSEDCKDN 180

PTCAVDIFSA GCVFYYVVSQ GSHPFGKSLQ RQANILLGTY SLDYLQTDKH GDIVARDLIE 240

QMLSVEPYKR PSAESLLKHP FF 262

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR011047	; Quinonprotein_ADH-like.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 5.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013