EKS-TAR-00449

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00449

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Ack	427.5	4.0E-128	115	375	261

Status

Unreviewed

Ensembl Protein

ENSTRUP00000003681

UniProt Accession

H2RU61;

Protein Name

Protein Synonyms/Alias

Gene Name

Tru.1895

Gene Synonyms/Alias

Tru.1895;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000001594	ENSTRUP00000003681	ENSTRUT00000003701
ENSTRUG00000001594	ENSTRUP00000003680	ENSTRUT00000003700
ENSTRUG00000001594	ENSTRUP00000003683	ENSTRUT00000003703
ENSTRUG00000001594	ENSTRUP00000003682	ENSTRUT00000003702
ENSTRUG00000001594	ENSTRUP00000003685	ENSTRUT00000003705
ENSTRUG00000001594	ENSTRUP00000003684	ENSTRUT00000003704
ENSTRUG00000001594	ENSTRUP00000003679	ENSTRUT00000003699
ENSTRUG00000001594	ENSTRUP00000003678	ENSTRUT00000003698
ENSTRUG00000001594	ENSTRUP00000003686	ENSTRUT00000003706
ENSTRUG00000001594	ENSTRUP00000003677	ENSTRUT00000003697

Organism

Takifugu rubripes

Functional Description

Protein Length

661

Protein Sequence
(FASTA)

MQCEEGTDWL LELLLEVQLQ QYFLRIRDDL NVTRLSHFDY VKNEDLEKIG MGRPGQRRLW 60

EAVKRRKAMC KRKSWMSKVT HTHTHTHTVF PPVFWRDLSG PEGLLTCLIP EKDLTLFEKL 120

GDGSFGVVKR GEWLTPTGKV LNVAVKCLKT DVLSQPDALE DFICEVNAMH SLDHQNLIRL 180

YGVVLTHPMK MVTELAPLGS LLERLRCVHP QGPVLIHTLC QYAVQVSCGM AYLEQRRFIH 240

RDLAARNILL ASAHKIKIGD FGLMRALPNN HEHYVMQEHR KVPFAWCAPE SLKTRTFSHA 300

TDTWMFGVTL WEMFTHGQEP WLGLNGSQIL HKIDKEGERL PKPEDCPQDI YNVMLQCWAQ 360

KPDDRPTFVA LREFLLETMP TDMCALEDFD EPDKLHIQLN DVITIIEGRA ENYWWRGQNK 420

RTLKVGQFPR NVVTSVAGLS AHDISRPLKN SFIHTGHGDS NPRRCWGFPD RIDDPAAAPA 480

SGLRRRGPGR RRHGEVCSIN SVEPLGEIKG SEQSSSEGDV RLPYSAQDQP PQVPPRDPLS 540

QPGSRTPSPR GPVVGSPHQR VYSVSPTAMQ APATTYGSYL STSPGRRRIC PWVQEAVHGV 600

TLEECQAALQ NHSWNVQKAT HYLKVEQLFC LGLRSRSECL KLLETCDWNL EVASTQMLDS 660

Y 661

Nucleotide Sequence
(FASTA)

ATGCAGTGTG AGGAGGGGAC GGACTGGCTG CTGGAGCTGC TGCTGGAGGT GCAGCTGCAG 60

CAGTACTTCC TGAGGATCCG GGACGACCTC AACGTCACCC GGCTGTCGCA CTTCGACTAC 120

GTCAAGAATG AAGACCTGGA GAAGATCGGC ATGGGGCGAC CCGGACAGAG AAGACTGTGG 180

GAAGCCGTCA AAAGGAGGAA AGCCATGTGC AAACGCAAGT CCTGGATGAG CAAGGTGACA 240

CACACACACA CACACACACA CACTGTTTTC CCACCAGTGT TTTGGCGTGA CCTCTCTGGG 300

CCTGAGGGTC TTCTGACGTG CCTCATCCCA GAGAAGGACC TGACTCTGTT TGAGAAGCTG 360

GGGGACGGCT CCTTCGGGGT TGTGAAGAGA GGGGAGTGGC TGACCCCCAC AGGGAAGGTG 420

CTGAACGTGG CCGTCAAGTG TCTGAAGACG GACGTTCTCA GCCAGCCCGA CGCTCTGGAG 480

GACTTCATCT GTGAGGTCAA CGCCATGCAC TCCCTGGACC ACCAGAACCT GATCCGCCTC 540

TATGGTGTGG TGCTCACACA CCCAATGAAG ATGGTGACGG AGCTGGCTCC TCTGGGTTCC 600

CTGCTGGAGC GTCTCCGGTG CGTGCATCCT CAGGGCCCCG TGCTGATCCA CACCCTGTGC 660

CAGTACGCGG TGCAGGTGTC CTGCGGCATG GCCTACCTGG AGCAGAGGAG GTTCATCCAC 720

AGAGACCTGG CAGCCAGGAA CATCCTTCTG GCCTCAGCCC ACAAAATAAA GATCGGGGAC 780

TTTGGCCTGA TGAGGGCGCT GCCCAACAAC CACGAGCACT ACGTCATGCA GGAGCACCGG 840

AAGGTTCCCT TTGCATGGTG CGCTCCAGAG AGTCTGAAGA CCAGGACGTT CTCCCACGCC 900

ACGGACACGT GGATGTTCGG CGTGACCCTG TGGGAGATGT TCACGCACGG CCAGGAGCCC 960

TGGCTGGGCC TCAACGGGAG CCAGATTCTG CACAAGATCG ATAAAGAAGG GGAACGCCTC 1020

CCGAAGCCTG AAGACTGTCC GCAGGACATC TACAACGTCA TGCTGCAGTG CTGGGCTCAG 1080

AAACCAGACG ACAGGCCGAC CTTCGTGGCC CTGCGCGAGT TCCTGCTCGA GACCATGCCC 1140

ACGGACATGT GTGCGCTGGA GGACTTTGAC GAGCCCGACA AACTCCACAT CCAGCTCAAC 1200

GACGTCATCA CCATTATCGA GGGCAGGGCG GAGAACTACT GGTGGCGCGG CCAAAACAAA 1260

CGCACCCTAA AGGTCGGCCA GTTCCCCCGA AACGTGGTGA CATCGGTCGC AGGCCTGTCG 1320

GCTCACGACA TCAGCCGGCC GCTCAAGAAC AGCTTCATCC ACACGGGACA CGGAGACAGC 1380

AACCCCCGGC GCTGCTGGGG CTTCCCCGAC AGGATTGACG ACCCGGCCGC TGCCCCCGCC 1440

TCCGGCCTAC GACGACGTGG CCCAGGACGA AGAAGACATG GAGAGGTTTG CTCCATCAAT 1500

AGTGTGGAGC CCCTGGGCGA GATCAAGGGT TCCGAGCAGT CGTCTTCGGA GGGGGACGTT 1560

CGCCTCCCAT ACTCAGCCCA GGACCAACCG CCCCAGGTCC CTCCCAGGGA CCCTCTGTCC 1620

CAGCCAGGCT CCAGGACTCC GAGCCCACGG GGCCCGGTGG TGGGTTCCCC CCATCAGAGG 1680

GTCTACTCTG TCAGCCCCAC CGCCATGCAA GCTCCAGCCA CCACCTACGG CTCCTACCTC 1740

TCCACCTCTC CAGGGAGGCG GAGAATCTGC CCCTGGGTGC AGGAGGCGGT TCATGGGGTC 1800

ACCCTGGAGG AGTGTCAGGC CGCCCTGCAG AACCACAGCT GGAACGTCCA GAAAGCCACG 1860

CATTACCTGA AGGTGGAGCA GTTGTTCTGT TTGGGTTTGA GGAGCCGCTC AGAGTGTCTG 1920

AAGCTGCTGG AGACGTGTGA CTGGAACCTG GAAGTCGCCA GCACTCAGAT GTTGGACAGC 1980

TAC 1983

Domain Profile

S: 2     klleklGeGsfgvvkrgeWsapsgksvqvavkvlksdkllstel.ddflrevsvllkleh  60

         +l eklG+GsfgvvkrgeW +p+gk+++vavk+lk+d+l+++++ +df+ ev+++++l+h

Q: 115   TLFEKLGDGSFGVVKRGEWLTPTGKVLNVAVKCLKTDVLSQPDAlEDFICEVNAMHSLDH  174

         7899***************************************99***************

S: 61    enlvrlyGvvltqplklvtelaelgslldrlrkeakrdsllvallleyavqiaeglayle  120

         +nl+rlyGvvlt+p+k+vtela+lgsll+rlr  + + ++l+++l++yavq++ g+ayle

Q: 175   QNLIRLYGVVLTHPMKMVTELAPLGSLLERLRCVHPQGPVLIHTLCQYAVQVSCGMAYLE  234

         ************************************************************

S: 121   skrlvhrdlaarnlllaskklvkisdfGlvralgeeedlyvlaenkkvPfaWcaPeslrt  180

         ++r++hrdlaarn+llas +++ki+dfGl+ral++++++yv++e++kvPfaWcaPesl+t

Q: 235   QRRFIHRDLAARNILLASAHKIKIGDFGLMRALPNNHEHYVMQEHRKVPFAWCAPESLKT  294

         ************************************************************

S: 181   rkfssasdvWafGvtlWemfsyGeePWvglsglqilkkidkekerlekPeacpediysll  240

         r+fs+a+d+W+fGvtlWemf++G+ePW gl+g+qil+kidke+erl+kPe+cp+diy+++

Q: 295   RTFSHATDTWMFGVTLWEMFTHGQEPWLGLNGSQILHKIDKEGERLPKPEDCPQDIYNVM  354

         ************************************************************

S: 241   lkcWakkpadrpkfsalkekl  261

         l+cWa+kp+drp+f+al+e+l

Q: 355   LQCWAQKPDDRPTFVALREFL  375

         *****************9976

Domain Sequence
(FASTA)

TLFEKLGDGS FGVVKRGEWL TPTGKVLNVA VKCLKTDVLS QPDALEDFIC EVNAMHSLDH 60

QNLIRLYGVV LTHPMKMVTE LAPLGSLLER LRCVHPQGPV LIHTLCQYAV QVSCGMAYLE 120

QRRFIHRDLA ARNILLASAH KIKIGDFGLM RALPNNHEHY VMQEHRKVPF AWCAPESLKT 180

RTFSHATDTW MFGVTLWEMF THGQEPWLGL NGSQILHKID KEGERLPKPE DCPQDIYNVM 240

LQCWAQKPDD RPTFVALREF L 261

Keyword

Complete proteome; G-protein coupled receptor; Membrane; Receptor; Reference proteome; Transducer; Transmembrane.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016021	; C:integral to membrane
GO:0005524	; F:ATP binding
GO:0004930	; F:G-protein coupled receptor activity
GO:0004713	; F:protein tyrosine kinase activity

KEGG

InterPros

IPR000276	; GPCR_Rhodpsn.
IPR017452	; GPCR_Rhodpsn_7TM.
IPR021619	; Inhibitor_Mig-6.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.
IPR009060	; UBA-like.
IPR015940	; UBA/transl_elong_EF1B_N_euk.

Pfam

PF00001	; 7tm_1; 1.
PF11555	; Inhibitor_Mig-6; 1.
PF07714	; Pkinase_Tyr; 1.

SMARTs

SM00219	; TyrKc; 1.
SM00165	; UBA; 2.

Prosites

PS00237	; G_PROTEIN_RECEP_F1_1; 1.
PS50262	; G_PROTEIN_RECEP_F1_2; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.
PS50030	; UBA; 1.

Prints

PR00237	; GPCRRHODOPSN.
PR00109	; TYRKINASE.

Created Date

20-Feb-2013