EKS-TAR-00336

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00336

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PLK	411.1	4.2E-123	15	267	253

Status

Unreviewed

Ensembl Protein

ENSTRUP00000003764

UniProt Accession

H2RUE6;

Protein Name

Protein Synonyms/Alias

Gene Name

PLK3

Gene Synonyms/Alias

PLK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000001633	ENSTRUP00000003763	ENSTRUT00000003783
ENSTRUG00000001633	ENSTRUP00000003764	ENSTRUT00000003784

Organism

Takifugu rubripes

Functional Description

Protein Length

543

Protein Sequence
(FASTA)

ELAPVVSDSM TGRSYSKGKL LGKGGFARCY EMTDLSNNHM YAVKVIPQSR VSKPHQREKI 60

LNEIELHRNL SHKHVVKFSH HFEDQDNIYI FLELCSRKSL AHIWKARHTL TDPEVRYYLR 120

QIISGLKYLH SRGILHRDLK LGNFFVNENM ELRLGDFGLA AKLETVEQRK KTICGTPNYL 180

APEVLNRQGH GPESDVWSLG CVMYTLMCGN PPFETLDLKE TYRCIKEVQY HLPSTISHPA 240

QKLISGILQK NPSDRLSLDQ ILSHEFFKFQ GFTPDKLPPS SCAMVPELHP PSPAKKFFAK 300

MAKSLFGKKK SKAVEKTLCE DKDEKDISKL VSGIVKCSIN RQISYKTVGP NEVRVHVRVH 360

RRELPQFFLW VTKWVDYSNK YGFGYQLSNQ SVGVLFNEGT HLSLCDQRST VHYCLTNNKH 420

FTFPADALPE QLHSQKEIVE LMANYMEQNL MEGGDLLCGE QASGAPPLLL QWVKTEHALV 480

MLFNNGTLQV NFYTDHTKII LCRSADDSYL LTYITRERVS YTYLLSMLTE MGCTSELRHR 540

LRY 543

Nucleotide Sequence
(FASTA)

GAGCTGGCGC CGGTGGTGAG CGACTCCATG ACGGGCAGGT CCTACAGCAA AGGGAAGCTC 60

CTGGGGAAGG GCGGCTTTGC TCGATGCTAC GAGATGACGG ACCTCTCCAA CAACCATATG 120

TACGCGGTGA AGGTGATCCC GCAGAGCAGG GTGTCGAAGC CGCACCAGAG AGAGAAGATA 180

TTGAACGAGA TCGAGCTCCA CAGAAACCTG TCGCACAAGC ATGTGGTCAA ATTCTCACAC 240

CACTTTGAAG ATCAGGACAA CATCTACATC TTCCTGGAGC TCTGCAGTCG AAAGTCCCTG 300

GCACACATTT GGAAAGCGAG GCACACTCTG ACCGACCCAG AGGTCCGATA TTACCTCAGA 360

CAGATCATCT CCGGGCTCAA GTACCTCCAC AGCCGCGGGA TCCTGCACAG AGACCTCAAA 420

CTAGGCAACT TCTTTGTCAA CGAGAACATG GAGCTGCGGC TGGGCGACTT CGGTCTGGCC 480

GCCAAACTGG AGACGGTGGA GCAGCGAAAA AAAACAATCT GCGGAACGCC CAATTACCTG 540

GCTCCCGAGG TGCTCAACAG GCAAGGCCAC GGCCCCGAGT CCGACGTCTG GTCCCTGGGT 600

TGCGTCATGT ACACGCTGAT GTGCGGCAAC CCGCCCTTCG AGACCCTGGA CCTGAAGGAG 660

ACCTACAGGT GCATCAAGGA GGTCCAGTAC CACCTGCCGT CCACCATCTC CCACCCTGCG 720

CAGAAGCTCA TCTCGGGCAT CCTGCAGAAG AACCCCAGCG ACAGACTCTC CCTGGACCAG 780

ATCCTCAGCC ACGAGTTCTT CAAGTTTCAG GGCTTCACCC CCGATAAGCT CCCCCCGAGC 840

AGCTGCGCCA TGGTACCAGA GCTTCACCCT CCAAGTCCTG CCAAGAAGTT CTTTGCAAAA 900

ATGGCCAAAA GCCTGTTTGG AAAGAAGAAG TCAAAGGCAG TGGAAAAGAC TCTGTGTGAG 960

GACAAGGACG AGAAGGACAT CTCCAAGCTG GTGTCTGGGA TCGTCAAATG TTCGATTAAC 1020

CGACAGATCA GCTACAAGAC CGTGGGGCCC AACGAGGTAC GCGTGCACGT GCGTGTGCAC 1080

AGACGTGAAC TACCCCAGTT CTTCCTGTGG GTGACCAAAT GGGTCGACTA CTCCAACAAG 1140

TATGGCTTTG GCTACCAGCT CTCCAACCAG AGTGTGGGGG TGCTCTTCAA CGAGGGAACG 1200

CACCTCAGCC TCTGCGACCA GCGCAGCACT GTCCACTACT GCCTGACCAA CAACAAACAC 1260

TTCACCTTCC CCGCCGACGC CCTCCCGGAG CAGCTGCACA GTCAGAAGGA GATTGTGGAG 1320

CTGATGGCCA ACTACATGGA GCAGAACCTG ATGGAGGGTG GTGATCTTCT GTGTGGGGAG 1380

CAGGCCTCGG GTGCCCCCCC CCTGCTGCTC CAGTGGGTGA AGACTGAGCA TGCTCTGGTG 1440

ATGCTCTTCA ACAACGGCAC TCTGCAGGTG AACTTCTACA CGGACCACAC CAAGATCATC 1500

CTGTGCAGGT CGGCCGACGA CTCCTACCTG CTGACCTACA TCACCCGGGA ACGGGTCTCG 1560

TACACGTACC TCCTCAGCAT GCTGACCGAG ATGGGCTGCA CTTCGGAGCT CCGGCACCGG 1620

CTGCGGTAC 1629

Domain Profile

S: 1     yergkllGkGgfakcyelkdletkevfavkvvpksllakekqrekvekeieihrslkhkn  60

         y++gkllGkGgfa+cye++dl++++++avkv+p+s++ k++qrek+ +eie+hr+l+hk+

Q: 15    YSKGKLLGKGGFARCYEMTDLSNNHMYAVKVIPQSRVSKPHQREKILNEIELHRNLSHKH  74

         89**********************************************************

S: 61    ivklyeffedkenvylvlelcsrrslaellkrrkaltepevryylrqivsglkylhekri  120

         +vk++++fed++n+y++lelcsr+sla+++k+r++lt+pevryylrqi+sglkylh++ i

Q: 75    VVKFSHHFEDQDNIYIFLELCSRKSLAHIWKARHTLTDPEVRYYLRQIISGLKYLHSRGI  134

         ************************************************************

S: 121   lhrdlklgnlflneelevkigdfGlatrlekeeerkktlcGtPnyiaPevlskkghslev  180

         lhrdlklgn+f+ne++e+++gdfGla++le+ e+rkkt+cGtPny+aPevl+++gh+ e+

Q: 135   LHRDLKLGNFFVNENMELRLGDFGLAAKLETVEQRKKTICGTPNYLAPEVLNRQGHGPES  194

         ************************************************************

S: 181   diWslGcilytllvGkPPfetkelketyekikkaeyslPsslskeaksliakllkkePee  240

         d+WslGc++ytl++G+PPfet +lkety++ik+ +y+lPs++s++a++li+ +l+k+P++

Q: 195   DVWSLGCVMYTLMCGNPPFETLDLKETYRCIKEVQYHLPSTISHPAQKLISGILQKNPSD  254

         ************************************************************

S: 241   rpsleevlkdefl  253

         r+sl+++l++ef+

Q: 255   RLSLDQILSHEFF  267

         ************8

Domain Sequence
(FASTA)

YSKGKLLGKG GFARCYEMTD LSNNHMYAVK VIPQSRVSKP HQREKILNEI ELHRNLSHKH 60

VVKFSHHFED QDNIYIFLEL CSRKSLAHIW KARHTLTDPE VRYYLRQIIS GLKYLHSRGI 120

LHRDLKLGNF FVNENMELRL GDFGLAAKLE TVEQRKKTIC GTPNYLAPEV LNRQGHGPES 180

DVWSLGCVMY TLMCGNPPFE TLDLKETYRC IKEVQYHLPS TISHPAQKLI SGILQKNPSD 240

RLSLDQILSH EFF 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000959	; POLO_box_duplicated_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR020658	; Ser/Thr_kinase_Plk3.

Pfam

PF00069	; Pkinase; 1.
PF00659	; POLO_box; 2.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50078	; POLO_BOX; 2.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013