EKS-TAR-00058

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00058

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/VRK	368.8	3.1E-110	24	287	264

Status

Unreviewed

Ensembl Protein

ENSTRUP00000005455

UniProt Accession

H2RZ84;

Protein Name

Protein Synonyms/Alias

Gene Name

VRK2

Gene Synonyms/Alias

VRK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000002366	ENSTRUP00000005454	ENSTRUT00000005487
ENSTRUG00000002366	ENSTRUP00000005453	ENSTRUT00000005486
ENSTRUG00000002366	ENSTRUP00000005455	ENSTRUT00000005488

Organism

Takifugu rubripes

Functional Description

Protein Length

404

Protein Sequence
(FASTA)

PKKGSLPKPL PEGFILSDSQ KKKWRLGKVI GQGGFGLIYL ASEDVGRPVA SDAAFVIKME 60

YLENGPLFTE LKFYQRAAKP DKIKSWKRSR RLDFLGIPTY WGAGLAEYDN ASYRFMVIDR 120

LGSDLQKVCE RSGGRMKKAT VLQLGQRLVS VLEYIHENEY VHADIKAANL LLGYRNPEQV 180

YLADYGLSYR YCPAGVHKEY KECPKKGHNG TIEYTSLDAH RGLAPSRRGD LQILGFCLLH 240

WLCGTLPWDN VLKDPIQVQK AKESLMDHLP HSVKHLSANT GKEVAKFLLH VKTLAYQEKP 300

DYQHLQDLLS SGASGGLDFS LSTGPTAGPL NESPEMSSSD EKDQLADDRA DSALPTSSRS 360

LRPRARITYK EHTSEEAEEE EEEEEAAAEE EEESEDEARP QPIS 404

Nucleotide Sequence
(FASTA)

CCAAAGAAAG GGTCGCTTCC CAAACCGCTG CCAGAGGGCT TCATTTTGAG CGACAGCCAG 60

AAGAAGAAAT GGCGTCTGGG GAAGGTCATC GGCCAAGGAG GGTTTGGCCT GATCTATCTG 120

GCCTCCGAGG ACGTGGGCAG ACCCGTCGCA TCAGATGCTG CCTTTGTCAT AAAAATGGAG 180

TACCTGGAGA ATGGACCCCT GTTTACAGAG CTCAAGTTCT ACCAGAGGGC AGCCAAACCA 240

GACAAGATTA AATCATGGAA GAGAAGCAGG AGACTGGACT TCCTGGGCAT CCCAACATAC 300

TGGGGAGCTG GGCTGGCTGA ATACGATAAT GCCAGTTATC GTTTTATGGT CATCGACCGT 360

CTGGGAAGTG ACCTCCAGAA AGTCTGTGAG CGCAGCGGAG GTCGAATGAA AAAGGCCACT 420

GTGCTCCAGC TCGGACAAAG ATTGGTGAGC GTGCTGGAGT ACATCCATGA GAACGAGTAC 480

GTCCACGCCG ACATCAAAGC TGCCAACCTT CTGCTGGGCT ACAGAAACCC TGAACAGGTT 540

TACCTGGCTG ATTATGGGCT GTCATACAGA TACTGTCCTG CTGGGGTCCA CAAAGAATAT 600

AAGGAATGCC CAAAGAAGGG CCACAATGGA ACCATTGAAT ACACCAGCCT TGATGCTCAC 660

AGAGGCCTTG CTCCATCCAG ACGTGGAGAC CTACAAATTT TGGGCTTTTG TCTTCTTCAC 720

TGGTTGTGTG GCACTCTCCC CTGGGACAAT GTCCTCAAAG ACCCGATTCA GGTCCAGAAG 780

GCCAAGGAGA GTCTGATGGA TCATCTGCCA CACTCGGTAA AGCACTTGTC TGCAAACACA 840

GGTAAGGAGG TGGCCAAATT CCTCCTTCAT GTGAAAACGC TGGCCTACCA AGAAAAGCCA 900

GACTACCAGC ATCTACAAGA CCTGCTGTCC AGTGGTGCCA GTGGGGGACT TGATTTCTCC 960

CTGTCCACGG GGCCCACAGC TGGGCCCCTA AACGAGTCCC CAGAGATGTC CAGCAGCGAT 1020

GAGAAAGATC AACTTGCCGA TGATAGAGCA GATTCAGCTT TACCTACAAG CAGCAGATCA 1080

CTGAGGCCAC GAGCTAGGAT CACTTATAAA GAGCATACCA GTGAGGAGGC GGAGGAGGAG 1140

GAGGAGGAGG AGGAGGCGGC GGCGGAGGAG GAGGAGGAGA GCGAGGATGA AGCCAGGCCA 1200

CAGCCCATCT CT 1212

Domain Profile

S: 1     wklgkkigkggfGeiyla..ltckkeekdaklvvkvepkenGpLfvelkfyqraakkeqi  58

         w+lgk ig+ggfG iyla   + + + +da +v+k+e+ enGpLf+elkfyqraak+++i

Q: 24    WRLGKVIGQGGFGLIYLAseDVGRPVASDAAFVIKMEYLENGPLFTELKFYQRAAKPDKI  83

         9*****************88889999**********************************

S: 59    kkwkkkkklkllgiPtliasGlhefegekyRflvlprlgrdLqklleqngkrlsektvlq  118

         k+wk+ ++l++lgiPt+++ Gl e+++ +yRf+v++rlg+dLqk+ e++g+r+++ tvlq

Q: 84    KSWKRSRRLDFLGIPTYWGAGLAEYDNASYRFMVIDRLGSDLQKVCERSGGRMKKATVLQ  143

         ************************************************************

S: 119   lavrlldvleylHeneYvHgdikAanllleeeeasqvyLvdyGlayrycpegkhkeyked  178

         l+ rl+ vley+HeneYvH+dikAanlll++++++qvyL+dyGl+yrycp g+hkeyke

Q: 144   LGQRLVSVLEYIHENEYVHADIKAANLLLGYRNPEQVYLADYGLSYRYCPAGVHKEYKEC  203

         ************************************************************

S: 179   krraHdGtleftslDaHkGvapsrRsDleiLgYcllkWltgkLPWeallkdpekvqkake  238

         +++ H+Gt+e+tslDaH+G apsrR+Dl+iLg+cll+Wl+g+LPW + lkdp +vqkake

Q: 204   PKKGHNGTIEYTSLDAHRGLAPSRRGDLQILGFCLLHWLCGTLPWDNVLKDPIQVQKAKE  263

         ************************************************************

S: 239   kfldelpellkkllkkkssseelaky  264

          ++d+lp+++k+l  ++ ++  +ak+

Q: 264   SLMDHLPHSVKHLSANTGKE--VAKF  287

         ***********998766544..5555

Domain Sequence
(FASTA)

WRLGKVIGQG GFGLIYLASE DVGRPVASDA AFVIKMEYLE NGPLFTELKF YQRAAKPDKI 60

KSWKRSRRLD FLGIPTYWGA GLAEYDNASY RFMVIDRLGS DLQKVCERSG GRMKKATVLQ 120

LGQRLVSVLE YIHENEYVHA DIKAANLLLG YRNPEQVYLA DYGLSYRYCP AGVHKEYKEC 180

PKKGHNGTIE YTSLDAHRGL APSRRGDLQI LGFCLLHWLC GTLPWDNVLK DPIQVQKAKE 240

SLMDHLPHSV KHLSANTGKE VAKF 264

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>