EKS-TAR-00217

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00217

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TTK	414.9	3.2E-124	28	290	263

Status

Unreviewed

Ensembl Protein

ENSTRUP00000006500

UniProt Accession

H2S275;

Protein Name

Protein Synonyms/Alias

Gene Name

TTK (1 of 2)

Gene Synonyms/Alias

TTK (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000002794	ENSTRUP00000006495	ENSTRUT00000006537
ENSTRUG00000002794	ENSTRUP00000006494	ENSTRUT00000006536
ENSTRUG00000002794	ENSTRUP00000006493	ENSTRUT00000006535
ENSTRUG00000002794	ENSTRUP00000006500	ENSTRUT00000006542
ENSTRUG00000002794	ENSTRUP00000006499	ENSTRUT00000006541
ENSTRUG00000002794	ENSTRUP00000006498	ENSTRUT00000006540
ENSTRUG00000002794	ENSTRUP00000006497	ENSTRUT00000006539
ENSTRUG00000002794	ENSTRUP00000006496	ENSTRUT00000006538

Organism

Takifugu rubripes

Functional Description

Protein Length

302

Protein Sequence
(FASTA)

CALKFNQNSS LTSISNESIT IKGKQFFVLK MIGRGGSSKV YQVLGHKNQL FAVKYVDLEE 60

ADAQTIESYK NEIEHLNHLQ QYSDQIIKLY DYEITNSYIY MLMECGNLDL NTWLRNRKTV 120

NPLERKFYWN NMLEAVQTIH NHGIVHSDLK PANFVIVNAS LKLIDFGIAN RIQPDVTSIM 180

KDSQVGTLNY MPPEAIKDTS SKPGKARSKI SPKGDVWSLG CILYCMTYGK TPFQSITNQI 240

AKLQAIIDPS HKIDFPDIPE KDLLDVLKRC LIRNPRERIC IAELLEHPYL QLKPQMSPQR 300

GI 302

Nucleotide Sequence
(FASTA)

TGTGCGTTAA AGTTCAATCA AAATTCTTCA TTAACTTCAA TTTCAAATGA ATCCATCACC 60

ATTAAGGGCA AACAGTTCTT TGTTCTTAAG ATGATTGGAC GTGGTGGTTC CAGCAAGGTC 120

TACCAGGTTC TTGGCCACAA GAACCAGCTT TTTGCTGTGA AATATGTTGA CCTGGAGGAA 180

GCGGATGCTC AGACTATAGA GAGCTACAAG AATGAGATCG AGCATCTGAA TCACCTGCAG 240

CAATACAGCG ATCAAATTAT TAAGCTATAC GACTATGAGA TAACCAACAG CTACATCTAT 300

ATGCTGATGG AATGTGGGAA CTTGGATCTG AACACTTGGC TGAGAAACCG CAAAACTGTG 360

AATCCCCTGG AGAGAAAGTT TTACTGGAAT AACATGCTGG AGGCTGTGCA AACTATCCAC 420

AATCATGGTA TTGTCCACAG TGACTTGAAG CCAGCGAACT TTGTCATTGT GAATGCTTCA 480

CTGAAGTTGA TTGACTTTGG CATTGCCAAC AGAATCCAGC CTGATGTTAC AAGTATTATG 540

AAGGATTCAC AGGTTGGAAC CCTGAACTAC ATGCCTCCAG AAGCCATCAA AGACACTTCG 600

TCCAAGCCAG GAAAAGCCCG TTCAAAGATA AGTCCCAAAG GAGATGTGTG GTCCCTTGGA 660

TGCATCCTGT ACTGCATGAC GTATGGGAAA ACACCATTCC AAAGCATCAC AAATCAGATT 720

GCCAAGCTGC AGGCCATAAT TGATCCTTCC CACAAGATTG ACTTTCCAGA TATACCAGAG 780

AAGGACCTGC TGGATGTTCT GAAGCGGTGT CTGATACGAA ACCCCAGAGA GAGAATTTGT 840

ATTGCTGAAC TGCTGGAGCA TCCATACCTT CAGCTAAAAC CACAAATGTC ACCGCAACGA 900

GGTATA 906

Domain Profile

S: 3     ilkklGsGGsskvfkvksekkrvyalkvvdleaaddqtidgykneielleklqdqs.kvi  61

         +lk +G+GGsskv++v+++k++ +a+k+vdle+ad qti++ykneie l+ lq+ s ++i

Q: 28    VLKMIGRGGSSKVYQVLGHKNQLFAVKYVDLEEADAQTIESYKNEIEHLNHLQQYSdQII  87

         6899**************************************************999***

S: 62    rlydyeledsllylvmecGdidlnkilkkkksiepdyelvsyykemleavkvihqhGivh  121

         +lydye+++s++y++mecG+ dln +l+++k+++p  e++ y+++mleav++ih+hGivh

Q: 88    KLYDYEITNSYIYMLMECGNLDLNTWLRNRKTVNP-LERKFYWNNMLEAVQTIHNHGIVH  146

         ***********************************.9***********************

S: 122   sdlkPanfllvdGilklidfGianavaedttsivkesqvGtvnylaPealkdmsssqsse  181

         sdlkPanf++v+  lklidfGian++++d tsi+k+sqvGt+ny++Pea+kd+ss

Q: 147   SDLKPANFVIVNASLKLIDFGIANRIQPDVTSIMKDSQVGTLNYMPPEAIKDTSSK----  202

         *****************************************************987....

S: 182   reaekskikvsrksdvwslGcilylllygktPfgsirnqvskllaiinPdveiefPeits  241

            +k+++k+s+k dvwslGcily ++ygktPf+si nq++kl+aii+P+++i+fP+i+

Q: 203   --PGKARSKISPKGDVWSLGCILYCMTYGKTPFQSITNQIAKLQAIIDPSHKIDFPDIP-  259

         ..8999*****************************************************.

S: 242   niekslvellkaclkrnPkkrisvdellsspfv  274

           ek+l ++lk cl rnP++ri + ell++p++

Q: 260   --EKDLLDVLKRCLIRNPRERICIAELLEHPYL  290

         ..*****************************95

Domain Sequence
(FASTA)

VLKMIGRGGS SKVYQVLGHK NQLFAVKYVD LEEADAQTIE SYKNEIEHLN HLQQYSDQII 60

KLYDYEITNS YIYMLMECGN LDLNTWLRNR KTVNPLERKF YWNNMLEAVQ TIHNHGIVHS 120

DLKPANFVIV NASLKLIDFG IANRIQPDVT SIMKDSQVGT LNYMPPEAIK DTSSKPGKAR 180

SKISPKGDVW SLGCILYCMT YGKTPFQSIT NQIAKLQAII DPSHKIDFPD IPEKDLLDVL 240

KRCLIRNPRE RICIAELLEH PYL 263

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR011990	; TPR-like_helical.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013