EKS-TAR-00545

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00545

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/ULK	319.3	4.8E-95	15	267	253

Status

Unreviewed

Ensembl Protein

ENSTRUP00000009076

UniProt Accession

H2S9K0;

Protein Name

Protein Synonyms/Alias

Gene Name

ULK3

Gene Synonyms/Alias

ULK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000003848	ENSTRUP00000009076	ENSTRUT00000009130

Organism

Takifugu rubripes

Functional Description

Protein Length

415

Protein Sequence
(FASTA)

MASSPSFAPP KLADFLLTER LGSGTYATVY KAYRKGDSRE VVAVKVVAKK TLNKASTENL 60

LTEIEILKSI RHPHIVQLKD FQWDADNIYL ILEWCSGGDL SRFIRSRRML PEKVARRFLQ 120

QMACALQFLH ERNISHLDLK PQNILLCGSV LKLADFGFAQ YMSPWDEHSV LRGSPLYMAP 180

EMVCRRQYDS RVDLWSVGVI LYEALFGRAP FASSFAELEE KIRSDQAVEL PPGSRVSQDC 240

RDLLLRLLER RPDTRITFAD FFSHPFVDLE HMPSADSLAT AKKLVLRAVE EDQAGQWSAA 300

LSHYCSALEH FVPAIHYETE AQRKDALRQK VSQYVSRAEE LKALLASHHR LSFEEARTST 360

GVLREMSRDQ PRLLAALNMA SAAIANEENG LTHEALDLYQ QCLGELLLVL AGSYP 415

Nucleotide Sequence
(FASTA)

ATGGCTTCCA GCCCCAGCTT CGCCCCACCC AAACTGGCCG ACTTCCTCCT GACGGAGCGA 60

CTGGGCAGCG GGACCTACGC CACCGTCTAC AAGGCCTACA GGAAGGGGGA CAGTCGGGAG 120

GTGGTGGCAG TAAAGGTGGT GGCTAAGAAG ACCCTGAACA AGGCGTCTAC GGAGAACCTG 180

CTCACAGAGA TTGAAATCCT CAAGTCCATC CGGCACCCTC ATATAGTTCA GCTCAAGGAT 240

TTCCAGTGGG ACGCTGACAA CATCTACCTG ATCCTGGAGT GGTGTTCTGG AGGAGATCTG 300

TCCCGGTTCA TCCGCAGTCG CCGGATGCTC CCTGAGAAGG TGGCCCGGCG CTTCCTGCAG 360

CAGATGGCCT GTGCTCTCCA GTTCCTCCAT GAACGAAACA TCTCTCACCT GGACCTGAAA 420

CCCCAGAATA TTTTGCTCTG CGGCTCCGTC CTCAAACTAG CAGATTTTGG CTTCGCCCAG 480

TACATGTCCC CCTGGGACGA GCACAGCGTC CTCAGAGGGT CCCCCCTCTA CATGGCCCCA 540

GAGATGGTGT GTCGCCGCCA GTACGACTCA AGGGTGGACC TGTGGTCCGT GGGGGTCATT 600

CTCTACGAAG CGCTCTTTGG CCGGGCACCG TTTGCATCAT CATTTGCTGA ATTGGAGGAG 660

AAGATCCGGA GTGACCAGGC TGTTGAGCTC CCTCCAGGGT CCAGGGTGTC CCAGGACTGC 720

CGAGACCTGC TGCTGCGCCT GCTGGAGCGG CGTCCAGACA CCAGGATCAC CTTTGCTGAC 780

TTCTTCAGCC ACCCCTTCGT GGACCTGGAG CACATGCCCA GCGCAGACAG CCTAGCGACC 840

GCGAAGAAGC TGGTCCTGCG AGCGGTGGAG GAGGACCAGG CGGGGCAGTG GTCCGCCGCC 900

CTGTCCCACT ACTGCAGTGC CCTTGAGCAT TTTGTCCCAG CGATTCACTA CGAGACGGAG 960

GCACAGCGGA AAGATGCCCT CAGGCAGAAG GTGAGCCAGT ACGTGTCCAG AGCCGAGGAG 1020

CTGAAGGCCC TGCTGGCCTC CCACCACAGG CTGAGCTTCG AGGAGGCCCG GACCTCCACA 1080

GGGGTCCTGC GAGAAATGTC CCGGGACCAA CCGCGACTTC TGGCTGCCCT GAACATGGCC 1140

TCAGCGGCCA TCGCTAACGA GGAGAACGGC CTGACCCACG AGGCTCTGGA CCTGTACCAG 1200

CAGTGCCTGG GGGAGCTCCT GCTGGTGTTG GCAGGTAGTT ACCCC 1245

Domain Profile

S: 1     ysleeeiGkGsfavvykgrlrkktsqvvAikvvekkkl.kkslenlekeikilkelkhen  59

         + l+e++G+G++a+vyk++ + ++++vvA+kvv+kk+l k+s+enl +ei+ilk+++h++

Q: 15    FLLTERLGSGTYATVYKAYRKGDSREVVAVKVVAKKTLnKASTENLLTEIEILKSIRHPH  74

         67899**************999****************9999******************

S: 60    ivalldveetskevylvmeycaggdLakllkqkkeLsedtvreflqqlasalkaLhskki  119

         iv+l+d++++++++yl++e+c+ggdL++++++++ L+e+++r+flqq+a al++Lh+++i

Q: 75    IVQLKDFQWDADNIYLILEWCSGGDLSRFIRSRRMLPEKVARRFLQQMACALQFLHERNI  134

         ************************************************************

S: 120   vhrDlkPqniLlsyadakkelkkvtlkladFglarvlkeesmaatlkGsplYmaPEvvke  179

         +h DlkPqniLl+            lkladFg+a++++ +++++ l+GsplYmaPE+v++

Q: 135   SHLDLKPQNILLC---------GSVLKLADFGFAQYMSPWDEHSVLRGSPLYMAPEMVCR  185

         *************.........7789**********************************

S: 180   qqydakaDlWSiGtilyellvGkpPfaaesiseLvekiekndvleppipkeisselkdll  239

         +qyd+++DlWS+G+ilye+l+G++Pfa +s+ eL+eki++++++e+p  +++s++++dll

Q: 186   RQYDSRVDLWSVGVILYEALFGRAPFA-SSFAELEEKIRSDQAVELPPGSRVSQDCRDLL  244

         **************************6.689*****************************

S: 240   qsLLqrdpkkRisfeelfahpfl  262

          +LL+r p +Ri+f+++f+hpf+

Q: 245   LRLLERRPDTRITFADFFSHPFV  267

         *********************96

Domain Sequence
(FASTA)

FLLTERLGSG TYATVYKAYR KGDSREVVAV KVVAKKTLNK ASTENLLTEI EILKSIRHPH 60

IVQLKDFQWD ADNIYLILEW CSGGDLSRFI RSRRMLPEKV ARRFLQQMAC ALQFLHERNI 120

SHLDLKPQNI LLCGSVLKLA DFGFAQYMSP WDEHSVLRGS PLYMAPEMVC RRQYDSRVDL 180

WSVGVILYEA LFGRAPFASS FAELEEKIRS DQAVELPPGS RVSQDCRDLL LRLLERRPDT 240

RITFADFFSH PFV 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR007330	; MIT.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF04212	; MIT; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00745	; MIT; 1.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013