EKS-TAR-00313

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00313

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	336.6	2.0E-100	31	283	253

Status

Unreviewed

Ensembl Protein

ENSTRUP00000009424

UniProt Accession

H2SAJ6;

Protein Name

Protein Synonyms/Alias

Gene Name

MARK2

Gene Synonyms/Alias

MARK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000003975	ENSTRUP00000009423	ENSTRUT00000009478
ENSTRUG00000003975	ENSTRUP00000009422	ENSTRUT00000009477
ENSTRUG00000003975	ENSTRUP00000009425	ENSTRUT00000009480
ENSTRUG00000003975	ENSTRUP00000009424	ENSTRUT00000009479
ENSTRUG00000003975	ENSTRUP00000009427	ENSTRUT00000009482
ENSTRUG00000003975	ENSTRUP00000009426	ENSTRUT00000009481
ENSTRUG00000003975	ENSTRUP00000009428	ENSTRUT00000009483
ENSTRUG00000003975	ENSTRUP00000009419	ENSTRUT00000009474
ENSTRUG00000003975	ENSTRUP00000009421	ENSTRUT00000009476
ENSTRUG00000003975	ENSTRUP00000009420	ENSTRUT00000009475

Organism

Takifugu rubripes

Functional Description

Protein Length

753

Protein Sequence
(FASTA)

ESKSSGRSSM SRCRNSVSTT TSEDQPHIGN YRLLKTIGKG NFAKVKLARH VLTGKEVAVK 60

IIDKTQLNSS SLQKLFREVR IMKLLNHPNI VKLFEVIETE KTLYLVMEYA SGGEVFDYLV 120

AHGRMKEKEA RAKFRLSVVN VSFSPLCLLV HVEVKAENLL LDADMNIKIA DFGFSNEFTL 180

GNKLDTFCGS PPYAAPELFQ GKKYDGPEVD VWSLGVILYT LVSGSLPFDG QNLKELRERV 240

LRGKYRIPFY MSTDCENLLK KFLILNPSKR GSLEQQIMRD RWMNVGYEDE ELKPYIEPQP 300

DYKDPKKTDI MLQMGFSLEE IQDSLVNQKY NDVMAAYLLL DYRNSELEEG CIKPRPGSEV 360

SNINAPSAPH KVQRSVSSNQ NPKNRRATEQ GHRCDAPGSS YSKRGGQADN RTAAEDSGRK 420

GSSGSSTTKV PASPAVSADR KKSATPSTNS ILSTGTGRSR NSPLNERATL GQGIQNGKDS 480

PTAASAARSQ TLATRARGRA SWPRQTQSSS CQGWSGHSGS FSNLGQTSKR GEAEQQSQRL 540

QKCPHTSRCV NNVANGAAAP AASPAPASEI SRSGFQEELS RKKTKQKELK VTLTTAPPGG 600

RGAYRNLFPI YDLTFLSRSP FEGEGQDEGS SPPPPPPGGT GTPPAIASQK DAAKPRSLRF 660

TWSMKTTSSM EPTEMMREIR KVLDSNSCEY EQRERYMLLC VSGNPAHDDF VQWEMEVCKL 720

PRLSLNGVRF KRISGTSIAF KNIASKVANE LKL 753

Nucleotide Sequence
(FASTA)

GAGTCCAAGT CATCCGGCCG CTCCAGCATG TCGCGGTGTC GGAACTCGGT CTCCACGACC 60

ACGTCGGAGG ACCAGCCGCA CATCGGCAAC TACCGGCTGC TGAAAACCAT CGGCAAAGGC 120

AACTTCGCCA AGGTCAAACT GGCACGACAC GTCCTCACGG GGAAGGAGGT GGCCGTGAAG 180

ATCATCGACA AGACGCAGCT CAACTCGTCC AGTTTGCAGA AGCTCTTCAG GGAGGTGAGG 240

ATCATGAAGC TGTTGAATCA CCCCAACATA GTGAAGCTCT TTGAGGTCAT AGAGACAGAG 300

AAGACTTTGT ACCTGGTAAT GGAGTACGCC AGTGGAGGTG AGGTCTTCGA CTACCTGGTG 360

GCCCACGGCC GGATGAAGGA AAAAGAAGCC CGCGCCAAAT TCCGACTGTC TGTGGTAAAT 420

GTCTCATTCT CCCCTTTGTG TTTATTAGTT CACGTGGAGG TCAAAGCCGA GAACCTGCTG 480

CTGGACGCAG ACATGAACAT CAAAATCGCC GACTTCGGCT TCAGCAACGA GTTCACTCTG 540

GGGAACAAGC TGGACACGTT CTGCGGCTCC CCGCCGTACG CCGCCCCCGA GCTCTTCCAG 600

GGCAAAAAAT ACGACGGGCC TGAGGTGGAC GTGTGGAGCC TGGGGGTCAT CCTCTACACG 660

CTGGTCAGCG GCTCGCTGCC CTTCGACGGG CAGAACCTCA AGGAACTGCG GGAGCGCGTC 720

CTGCGCGGCA AATACAGGAT CCCTTTCTAC ATGTCCACCG ACTGCGAGAA CCTGCTCAAG 780

AAGTTCCTCA TCCTGAACCC TTCCAAAAGA GGCAGCCTCG AGCAGCAGAT CATGAGGGAC 840

CGGTGGATGA ACGTGGGCTA CGAGGACGAG GAACTCAAGC CGTACATCGA ACCCCAGCCG 900

GATTATAAAG ACCCCAAAAA AACCGATATT ATGCTACAAA TGGGATTCTC CCTGGAGGAG 960

ATCCAGGACT CACTGGTGAA CCAGAAGTAC AACGACGTGA TGGCCGCGTA TCTGCTTCTC 1020

GACTACAGGA ACTCCGAGTT GGAGGAAGGT TGCATCAAGC CTAGACCAGG AAGTGAAGTA 1080

AGCAACATAA ACGCCCCTTC TGCGCCTCAC AAGGTACAGC GCAGCGTGTC GTCCAACCAG 1140

AACCCTAAGA ACCGCAGAGC CACCGAACAG GGACATCGTT GTGATGCACC AGGGTCTTCC 1200

TACTCCAAGA GGGGCGGACA AGCGGACAAC AGGACCGCAG CAGAGGATTC TGGGAGGAAA 1260

GGCTCGTCGG GCAGCTCCAC CACGAAGGTG CCGGCCAGCC CCGCGGTCTC AGCCGACCGT 1320

AAGAAGAGCG CCACGCCTTC CACCAACAGC ATCCTGTCCA CCGGCACCGG TCGCAGTCGA 1380

AACTCGCCTC TCAACGAGAG AGCCACGCTG GGTCAGGGCA TCCAGAACGG CAAGGACAGT 1440

CCCACAGCTG CCTCAGCGGC CCGATCCCAG ACGTTGGCCA CCAGGGCCCG GGGCCGTGCC 1500

AGCTGGCCCC GACAGACCCA GAGCTCTTCC TGCCAGGGCT GGTCAGGCCA CTCGGGCTCC 1560

TTCTCAAATT TAGGCCAAAC CTCAAAACGC GGCGAAGCAG AGCAACAAAG CCAACGGCTG 1620

CAGAAGTGTC CTCACACTTC GAGGTGTGTC AATAATGTCG CAAACGGCGC CGCCGCTCCA 1680

GCGGCCTCGC CAGCGCCGGC CTCCGAAATC TCTCGTTCAG GTTTCCAAGA AGAACTTTCG 1740

AGGAAAAAAA CCAAACAAAA GGAGCTCAAA GTGACCTTGA CCACAGCGCC CCCTGGCGGC 1800

CGTGGGGCGT ATCGCAATTT ATTCCCAATT TATGATCTGA CATTTCTCTC AAGGAGTCCA 1860

TTTGAGGGAG AGGGTCAGGA TGAGGGGAGC AGTCCCCCCC CCCCCCCTCC AGGCGGCACC 1920

GGCACCCCTC CGGCCATCGC CAGCCAGAAG GACGCCGCCA AGCCGCGCTC GCTCCGCTTC 1980

ACCTGGTCCA TGAAGACCAC CTCCTCCATG GAGCCCACGG AGATGATGCG CGAGATCCGC 2040

AAGGTGCTCG ACTCCAACAG CTGCGAGTAC GAGCAGCGCG AGCGCTACAT GCTGCTGTGC 2100

GTGTCGGGCA ACCCGGCGCA CGACGACTTC GTCCAGTGGG AGATGGAGGT GTGCAAGCTG 2160

CCGCGGCTCT CCCTCAACGG CGTGCGCTTC AAGCGCATCT CGGGGACCTC CATCGCCTTC 2220

AAGAACATTG CCTCAAAGGT CGCCAACGAG CTCAAACTGT GA 2262

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpni  60

         y+llkt+G+g+f+kVkla+h +t+++vavKii+k++l+++sl+k++rE++i+k l+hpni

Q: 31    YRLLKTIGKGNFAKVKLARHVLTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKLLNHPNI  90

         99**********************************************************

S: 61    ikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgiv  120

         +kl+eviet+k+lylv+eyasgge+fdy++++gr+kekear+ f+  v  v++   + +v

Q: 91    VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRLSVVNVSFSPLCLLV  150

         ************************************************************

S: 121   HrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvD  180

         H ++K+eNllld+++nikiaDFG++n+f+ g++l+tfcGsppYaaPel++gkkY+gp+vD

Q: 151   HVEVKAENLLLDADMNIKIADFGFSNEFTLGNKLDTFCGSPPYAAPELFQGKKYDGPEVD  210

         ************************************************************

S: 181   vWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpekR  240

         vWslGv+Ly+lv+g+lPfd++nlkel+e++l+gk++ip+++s+++e+Ll+k+L  +p+kR

Q: 211   VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKR  270

         ************************************************************

S: 241   atie.eilkhewl  252

          ++e +i++++w+

Q: 271   GSLEqQIMRDRWM  283

         **9637******7

Domain Sequence
(FASTA)

YRLLKTIGKG NFAKVKLARH VLTGKEVAVK IIDKTQLNSS SLQKLFREVR IMKLLNHPNI 60

VKLFEVIETE KTLYLVMEYA SGGEVFDYLV AHGRMKEKEA RAKFRLSVVN VSFSPLCLLV 120

HVEVKAENLL LDADMNIKIA DFGFSNEFTL GNKLDTFCGS PPYAAPELFQ GKKYDGPEVD 180

VWSLGVILYT LVSGSLPFDG QNLKELRERV LRGKYRIPFY MSTDCENLLK KFLILNPSKR 240

GSLEQQIMRD RWM 253

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pteropus vampyrus"; ?>Sus scrofa"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR001772	; Kinase-assoc_KA1.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR015940	; UBA/transl_elong_EF1B_N_euk.

Pfam

PF02149	; KA1; 1.
PF07714	; Pkinase_Tyr; 1.

SMARTs

SM00220	; S_TKc; 1.
SM00165	; UBA; 1.

Prosites

PS50032	; KA1; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS50030	; UBA; 1.

Prints

Created Date

20-Feb-2013