EKS-TAR-00258

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00258

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	491.4	1.8E-147	4	284	281

Status

Unreviewed

Ensembl Protein

ENSTRUP00000012445

UniProt Accession

H2SJ58;

Protein Name

Protein Synonyms/Alias

Gene Name

MAK

Gene Synonyms/Alias

MAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000005187	ENSTRUP00000012441	ENSTRUT00000012501
ENSTRUG00000005187	ENSTRUP00000012442	ENSTRUT00000012502
ENSTRUG00000005187	ENSTRUP00000012443	ENSTRUT00000012503
ENSTRUG00000005187	ENSTRUP00000012445	ENSTRUT00000012505
ENSTRUG00000005187	ENSTRUP00000012444	ENSTRUT00000012504
ENSTRUG00000005187	ENSTRUP00000012447	ENSTRUT00000012507
ENSTRUG00000005187	ENSTRUP00000012446	ENSTRUT00000012506

Organism

Takifugu rubripes

Functional Description

Protein Length

611

Protein Sequence
(FASTA)

MNRYTTLKQL GDGTYGSVLM GRSNESGELV AIKRMKRKFY SWEECMNLRE VKALKKLNHA 60

NVVKLKEVIR ENDHLYFVFE YMKENLYQLM KDRKKLFPES VSRNISFQIL QGLSFIHKHG 120

FFHRDMKPEN LLCMGPELVK IADFGLAREI RSKPPYTDYV STRWYRAPEV LLRSSNYSSA 180

IDLWAVGCIM AELYTLRPLF PGNSEVDEIF KICQVLGTVK KTDWPEGYQL ASAMNFRFPQ 240

CVPTHLKTLI PHASNEAIAL MRDLLQWDPK KRPTAVQSLR YPYFQVGQIL GPHPQSQEVK 300

NARPVPQKQL SEPKPTESKV FTDTRKQQQH PHQPLQQIPL PQTEKPGGVS NAKPSPTGSE 360

NTIGGGTGTL KNGRRRWGQS KTRESREELD PPEMSVSTSK KEQRSLKEHQ PLCSNAQTPA 420

FPSVCRPKVQ EPLYSFSTLT KLPSHVKISQ PDCNLPTSAA RQHYLSQSRY LPDLSGMTLR 480

DLWDNSSNNV NKPLAPPLGL SVSRANVGKA VIKEIRNTGN FVSAKYNLSS AYMPSFQKKE 540

VGSVGQRIQL APLVGQHTNY EAWKKRADRT EVKGSNYSVL GRTAGNLLSS AAAVQPVHGR 600

VDWTSKYGGN R 611

Nucleotide Sequence
(FASTA)

ATGAATCGCT ACACCACCCT GAAGCAGCTG GGTGACGGCA CATACGGCAG CGTGCTGATG 60

GGGAGAAGCA ACGAGTCTGG TGAACTAGTC GCTATAAAGA GAATGAAGAG GAAGTTTTAT 120

TCATGGGAGG AATGTATGAA TCTAAGAGAG GTGAAGGCAC TTAAGAAGCT GAACCATGCC 180

AATGTGGTGA AACTGAAAGA GGTTATCCGA GAAAACGATC ATCTGTATTT TGTCTTTGAG 240

TATATGAAGG AAAACCTCTA CCAGCTCATG AAGGACAGAA AAAAACTGTT CCCTGAGTCA 300

GTGAGTCGAA ATATAAGCTT TCAGATTTTA CAAGGCCTGT CATTTATTCA CAAACATGGT 360

TTCTTCCATC GAGACATGAA ACCTGAGAAT CTGTTGTGCA TGGGGCCAGA GCTGGTCAAA 420

ATAGCAGATT TTGGCCTGGC CCGAGAGATC CGCTCCAAAC CTCCGTATAC AGACTACGTA 480

TCGACTAGAT GGTACCGAGC TCCAGAGGTG CTGCTCCGCT CTTCTAACTA CAGCTCTGCC 540

ATTGACCTGT GGGCTGTGGG CTGCATCATG GCTGAGCTCT ACACTCTTAG GCCTCTTTTC 600

CCTGGAAACA GTGAAGTCGA TGAGATCTTT AAGATCTGCC AAGTCCTGGG CACTGTCAAA 660

AAGACAGATT GGCCAGAAGG TTACCAGCTC GCTTCTGCTA TGAATTTCCG GTTCCCCCAA 720

TGTGTTCCAA CCCATCTGAA GACCCTCATC CCTCATGCCA GTAATGAGGC CATTGCCTTG 780

ATGAGGGACC TGCTGCAATG GGACCCCAAA AAAAGACCCA CTGCAGTACA GTCCCTGCGT 840

TACCCATATT TCCAAGTGGG CCAGATCTTA GGACCCCATC CTCAGAGCCA GGAGGTTAAA 900

AACGCTAGGC CGGTCCCGCA GAAGCAGCTC TCCGAGCCCA AGCCCACTGA ATCCAAAGTG 960

TTCACCGACA CCAGGAAGCA ACAGCAACAT CCTCACCAGC CTCTTCAGCA GATCCCACTT 1020

CCTCAAACTG AGAAACCTGG AGGAGTCAGC AATGCAAAAC CATCACCTAC AGGCAGTGAG 1080

AATACCATCG GTGGTGGGAC GGGGACGCTA AAGAATGGGC GTCGTCGCTG GGGACAATCG 1140

AAAACCAGAG AAAGCAGGGA GGAGCTTGAC CCCCCCGAAA TGTCTGTTTC TACCTCCAAG 1200

AAGGAGCAGA GGAGCCTCAA GGAGCACCAG CCACTGTGTA GCAATGCTCA GACACCTGCC 1260

TTCCCTTCTG TGTGTAGGCC CAAGGTCCAG GAACCTCTCT ATTCATTCAG CACCCTCACA 1320

AAGTTACCCA GCCATGTTAA GATCAGCCAG CCAGACTGCA ACCTTCCAAC ATCTGCTGCT 1380

CGACAGCACT ACCTAAGCCA GTCCCGATAT TTACCAGATT TGAGTGGTAT GACGCTTCGA 1440

GATCTATGGG ATAATTCCTC CAACAATGTA AATAAACCAC TTGCTCCTCC ATTAGGATTA 1500

TCTGTCAGCA GAGCCAATGT TGGAAAGGCT GTCATTAAAG AAATACGTAA TACAGGGAAC 1560

TTTGTAAGCG CCAAATACAA CCTCTCTAGT GCTTATATGC CTTCATTCCA AAAGAAAGAG 1620

GTGGGCTCCG TGGGGCAGAG AATCCAACTT GCCCCCTTGG TTGGCCAGCA TACAAATTAT 1680

GAGGCCTGGA AGAAAAGGGC AGATCGGACA GAGGTGAAAG GGAGCAACTA CTCAGTTCTG 1740

GGGAGAACTG CTGGGAACCT GCTGAGCAGT GCTGCTGCTG TACAGCCGGT CCACGGCAGG 1800

GTGGACTGGA CCTCCAAATA TGGTGGAAAT AGATAG 1836

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++k+lGdGt+g+vl+++s+++gelvaik+mkrkf+s+ee++nlrevk+lkkln h+n+

Q: 4     YTTLKQLGDGTYGSVLMGRSNESGELVAIKRMKRKFYSWEECMNLREVKALKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         +klkevi  rend+ly+v+e+m+enlyql+kdr+kl++es+ ++i +qil+gl+fihkhg

Q: 63    VKLKEVI--RENDHLYFVFEYMKENLYQLMKDRKKLFPESVSRNISFQILQGLSFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrd+kPen+l++g+elvk+adfGlare+rsk+PytdyvstrwyraPevllrs++yss

Q: 121   FFHRDMKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSSNYSSA  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +dlwavGc++ae+++lrplfPG se+d+ifki++vlGt kk++w+e+y+lasa+n++fpq

Q: 181   IDLWAVGCIMAELYTLRPLFPGNSEVDEIFKICQVLGTVKKTDWPEGYQLASAMNFRFPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         ++++ lktl+++as+ea+ l++dll++dP++r+ta q+l+ypyf

Q: 241   CVPTHLKTLIPHASNEAIALMRDLLQWDPKKRPTAVQSLRYPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTLKQLGDG TYGSVLMGRS NESGELVAIK RMKRKFYSWE ECMNLREVKA LKKLNHANVV 60

KLKEVIREND HLYFVFEYMK ENLYQLMKDR KKLFPESVSR NISFQILQGL SFIHKHGFFH 120

RDMKPENLLC MGPELVKIAD FGLAREIRSK PPYTDYVSTR WYRAPEVLLR SSNYSSAIDL 180

WAVGCIMAEL YTLRPLFPGN SEVDEIFKIC QVLGTVKKTD WPEGYQLASA MNFRFPQCVP 240

THLKTLIPHA SNEAIALMRD LLQWDPKKRP TAVQSLRYPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013