EKS-TAR-00360

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00360

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	442.8	1.2E-132	235	522	288

Status

Unreviewed

Ensembl Protein

ENSTRUP00000013366

UniProt Accession

H2SLT2;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR1B (3 of 3)

Gene Synonyms/Alias

BMPR1B (3 of 3);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000005555	ENSTRUP00000013367	ENSTRUT00000013429
ENSTRUG00000005555	ENSTRUP00000013366	ENSTRUT00000013428
ENSTRUG00000005555	ENSTRUP00000013368	ENSTRUT00000013430

Organism

Takifugu rubripes

Functional Description

Protein Length

533

Protein Sequence
(FASTA)

AGWMDSPSDQ IGQLLNYFFA SFLAGNILDS MLLKASNREA AGSGKESGGS AAPAPSAQRL 60

LWCHCYHYCP EDSTNNTCRT DGYCFTMVEE EAAGVPVQTA GCLGLGGSVF QCRDTVGSQQ 120

RRSIECCTDE DYCNKNLHPT LPPLKPPLYV DGKIHHMALL VSVTVCSLIL VTVIIFCYIR 180

YRRQESRPRY SIGLEQDESY SLPGESLKDL IEQSQSSGSG SGLPLLVQRT IAKQIQMVKQ 240

IGKGRYGEVW MGKWRGEKVA VKVFFTTDEA SWSRETEIYQ TVLMRHENIL GFIAADIKGT 300

GSWTQLYLIT DCHENGSLYD YLKSTTLDNK AMLRLAYSSV SGLCHLHTEI FGTQGKPAIA 360

HRDLKSKNIL VKRNGTCCIA DLGLAVKFIS DTNEVDIPPN TKVGTKRYMP PEVLDETLNK 420

SHFQSYIMAD MYSFGLILWE IARRCISGGI LEEYQLPYHE LVPTDPSYED MKEVVCIKRL 480

RPSFPNRWTS DECLRQMGKL MTECWAHNPG SRLTALRVKK TLAKMSESQD IKL 533

Nucleotide Sequence
(FASTA)

GCGGGATGGA TGGATTCTCC CTCAGATCAA ATCGGTCAAT TGTTAAACTA CTTTTTTGCT 60

TCTTTCCTTG CAGGAAACAT ATTGGACAGT ATGCTGCTGA AAGCCTCCAA TAGGGAGGCA 120

GCGGGGAGCG GGAAGGAGAG CGGCGGCAGC GCAGCTCCGG CACCGTCCGC CCAGAGACTT 180

CTGTGGTGCC ACTGTTACCA CTACTGCCCC GAAGACTCCA CCAACAACAC GTGCAGGACG 240

GATGGCTACT GTTTCACCAT GGTGGAGGAG GAGGCGGCGG GGGTTCCGGT CCAGACTGCG 300

GGCTGCCTGG GGCTGGGCGG CTCAGTGTTT CAGTGCCGGG ACACGGTGGG CTCACAACAA 360

AGGAGATCCA TCGAGTGTTG CACCGACGAG GATTACTGCA ACAAGAACCT GCATCCCACC 420

CTGCCGCCGC TCAAGCCTCC CCTCTACGTC GATGGGAAGA TCCACCACAT GGCCCTGCTG 480

GTCTCTGTCA CCGTGTGCAG CCTCATACTG GTCACCGTCA TCATCTTCTG CTACATTAGG 540

TACAGGCGTC AGGAGTCTCG TCCTCGGTAC AGTATCGGCC TGGAGCAGGA TGAGAGTTAC 600

AGCCTGCCTG GAGAGTCTTT GAAGGACCTG ATCGAACAGT CCCAAAGCTC TGGCTCAGGC 660

TCGGGGCTCC CTCTGTTGGT GCAGAGAACG ATAGCCAAAC AGATCCAGAT GGTGAAGCAG 720

ATAGGCAAGG GCCGCTATGG AGAGGTGTGG ATGGGAAAGT GGCGGGGCGA GAAGGTTGCC 780

GTCAAAGTTT TCTTCACCAC CGACGAGGCC AGTTGGTCCA GAGAGACTGA GATCTATCAG 840

ACCGTCTTGA TGCGACACGA GAACATTCTG GGTTTCATTG CCGCTGATAT TAAAGGCACT 900

GGCTCCTGGA CCCAGCTCTA CCTGATCACC GACTGCCACG AAAACGGCTC CTTGTACGAC 960

TACCTCAAAT CCACCACGCT GGACAACAAA GCCATGCTGA GACTGGCGTA CTCCTCCGTG 1020

TCGGGCCTCT GTCACCTCCA CACCGAGATC TTCGGCACCC AAGGCAAGCC GGCCATCGCC 1080

CACAGGGACC TGAAGAGCAA GAACATCCTG GTGAAAAGGA ACGGGACCTG CTGCATCGCC 1140

GACCTGGGAC TGGCGGTCAA GTTTATCAGT GACACCAATG AGGTCGACAT CCCCCCCAAC 1200

ACTAAAGTTG GTACCAAGCG CTACATGCCG CCAGAGGTCC TGGACGAGAC TCTGAACAAA 1260

AGTCACTTTC AGTCGTACAT CATGGCGGAC ATGTACAGCT TTGGGCTCAT CCTCTGGGAG 1320

ATCGCTCGGC GCTGCATCTC AGGAGGGATC CTTGAGGAGT ACCAGTTGCC CTATCATGAG 1380

TTAGTTCCAA CGGACCCTTC GTATGAAGAC ATGAAAGAGG TGGTCTGCAT CAAGAGACTA 1440

CGGCCGTCCT TTCCCAACCG ATGGACCAGC GACGAGTGTT TGAGACAGAT GGGGAAGCTC 1500

ATGACCGAAT GCTGGGCCCA CAACCCCGGC TCCCGCCTCA CGGCCCTCCG AGTGAAAAAG 1560

ACACTGGCCA AGATGTCAGA ATCACAGGAC ATCAAGCTGT GA 1602

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         ++++++igkGrygeVw++k+rge+vAvK+f+t+deasw rE+eiyqtvl+rhenil+fia

Q: 235   IQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTDEASWSRETEIYQTVLMRHENILGFIA  294

         799*********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k ++s+t+l+l+t+ he+gsL+dyLk++tld + +lrla+s +sGl+hLH+ei+gt+

Q: 295   ADIKGTGSWTQLYLITDCHENGSLYDYLKSTTLDNKAMLRLAYSSVSGLCHLHTEIFGTQ  354

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  KpaiaHRDlkskNilvk+++tcciaDlGLa+k+ ++++e+d+  n++vGtkRYm PE

Q: 355   G--KPAIAHRDLKSKNILVKRNGTCCIADLGLAVKFISDTNEVDIPPNTKVGTKRYMPPE  412

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vl+e+ln ++f+++ +aD+Ys+gL+lWE+a+Rc + +++ eey+lp++e v++dPs+e+m

Q: 413   VLDETLNKSHFQSYIMADMYSFGLILWEIARRCIS-GGILEEYQLPYHELVPTDPSYEDM  471

         ***********************************.************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         kevv+ k+lrP++p++w+++e+l+++ kl++ecW+++p +Rltalrvkk+l

Q: 472   KEVVCIKRLRPSFPNRWTSDECLRQMGKLMTECWAHNPGSRLTALRVKKTL  522

         *************************************************97

Domain Sequence
(FASTA)

IQMVKQIGKG RYGEVWMGKW RGEKVAVKVF FTTDEASWSR ETEIYQTVLM RHENILGFIA 60

ADIKGTGSWT QLYLITDCHE NGSLYDYLKS TTLDNKAMLR LAYSSVSGLC HLHTEIFGTQ 120

GKPAIAHRDL KSKNILVKRN GTCCIADLGL AVKFISDTNE VDIPPNTKVG TKRYMPPEVL 180

DETLNKSHFQ SYIMADMYSF GLILWEIARR CISGGILEEY QLPYHELVPT DPSYEDMKEV 240

VCIKRLRPSF PNRWTSDECL RQMGKLMTEC WAHNPGSRLT ALRVKKTL 288

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0004702	; F:receptor signaling protein serine/threonine kinase activity
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0023014	; P:signal transduction by phosphorylation

KEGG

InterPros

IPR000333	; Activin_II/TGFBeta-II_recpt.
IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00653

; ACTIVIN2R.

Created Date

20-Feb-2013