EKS-TAR-00369

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00369

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	366.2	2.7E-109	199	499	301

Status

Unreviewed

Ensembl Protein

ENSTRUP00000015276

UniProt Accession

H2SS87;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR2

Gene Synonyms/Alias

BMPR2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000006256	ENSTRUP00000015280	ENSTRUT00000015349
ENSTRUG00000006256	ENSTRUP00000015272	ENSTRUT00000015341
ENSTRUG00000006256	ENSTRUP00000015273	ENSTRUT00000015342
ENSTRUG00000006256	ENSTRUP00000015274	ENSTRUT00000015343
ENSTRUG00000006256	ENSTRUP00000015275	ENSTRUT00000015344
ENSTRUG00000006256	ENSTRUP00000015276	ENSTRUT00000015345
ENSTRUG00000006256	ENSTRUP00000015277	ENSTRUT00000015346
ENSTRUG00000006256	ENSTRUP00000015278	ENSTRUT00000015347
ENSTRUG00000006256	ENSTRUP00000015279	ENSTRUT00000015348

Organism

Takifugu rubripes

Functional Description

Protein Length

535

Protein Sequence
(FASTA)

FFPDKLKFCA NLSVFPAAQG EERECAFTDQ QQQWEVERMA GGEGRISPEN TTVRCGKGSH 60

CFGLWEKSPP GEVRLVKQGC WTHLGDHQGC RDDRCVVTNL PPQIQNGTYH FCCCGSDMCN 120

VNFTEDFPQP SPTTAQPICN PESINTVIIT VATVSVLAVL AVAAFFGYRM MHGDGKQGLH 180

NLNMMEAAGS ESSLDLDNLK LLELIGRGRY GTVYCGSLDE RPVAVKVFTA TNRQNFLNEC 240

SIYRLPLLEH DNIARFVAAD ERTGSEGRTE YLLVMEYYPH GSLNRYLSVQ TNDWVSSCRL 300

AHSVTRGLAY LHTELFKGDL YKPAVSHRDL NSRNVLVKAD GTCVIIDFGL SMKLTGNRPA 360

RHGEEENAAI SEVGTIRYMA PEVLEGAVNL RDCESALKQV DMYALGLLYW ETFMRCTDLF 420

PGEAVPEYQM AFQAETEAGN HPTFEDMQVL VSREKQRPKF PEAWKENSLA VRSLKETMED 480

CWDQDAEARL TAQCAEERLA ELLLIWDRSK SVSPTLNPMS TTLHNERWTP TCNTW 535

Nucleotide Sequence
(FASTA)

TTTTTTCCAG ATAAACTGAA GTTCTGCGCA AATCTCTCTG TCTTTCCAGC AGCCCAGGGT 60

GAGGAACGTG AATGTGCCTT CACAGACCAG CAGCAGCAGT GGGAGGTGGA GCGAATGGCA 120

GGGGGTGAAG GTCGGATCTC ACCGGAGAAC ACCACTGTCA GATGTGGCAA GGGCAGCCAC 180

TGCTTTGGTC TGTGGGAGAA AAGCCCCCCA GGCGAGGTGC GACTCGTGAA ACAAGGTTGC 240

TGGACCCACC TGGGTGACCA CCAGGGTTGC CGCGATGACC GCTGCGTTGT GACGAACCTC 300

CCTCCGCAGA TCCAAAATGG GACGTACCAT TTTTGCTGCT GTGGCAGCGA CATGTGCAAC 360

GTCAACTTCA CGGAGGACTT CCCGCAGCCC AGCCCCACCA CGGCTCAGCC CATCTGTAAT 420

CCAGAGAGTA TTAATACAGT AATTATCACC GTAGCAACAG TATCCGTGCT GGCCGTGCTC 480

GCTGTAGCAG CCTTCTTTGG TTACCGCATG ATGCACGGTG ACGGTAAGCA AGGTCTCCAC 540

AATCTGAACA TGATGGAGGC TGCCGGATCC GAGAGCTCTC TGGATCTGGA CAATCTAAAG 600

CTGCTGGAGC TCATCGGCCG GGGACGATAC GGCACCGTCT ACTGTGGCTC TCTGGATGAA 660

CGGCCAGTAG CTGTGAAAGT GTTCACGGCT ACCAACCGGC AGAATTTTCT TAACGAATGC 720

TCCATATACC GGCTGCCGCT GCTGGAGCAT GACAACATCG CCAGGTTTGT TGCTGCTGAC 780

GAGAGGACGG GCTCAGAGGG GCGCACCGAG TACCTGCTGG TGATGGAGTA CTACCCACAC 840

GGGTCGCTCA ATCGTTACCT GAGCGTCCAG ACCAACGACT GGGTCAGCAG CTGCCGGCTT 900

GCTCACTCTG TTACCCGCGG CCTGGCGTAC CTGCACACGG AGCTCTTTAA AGGAGACCTG 960

TACAAGCCCG CCGTTTCACA CCGAGATCTG AACAGCCGAA ATGTTCTGGT CAAAGCTGAC 1020

GGCACTTGCG TCATCATTGA TTTTGGCTTG TCCATGAAGC TGACGGGAAA TAGGCCCGCG 1080

CGTCACGGAG AAGAAGAGAA CGCTGCTATA AGTGAGGTGG GAACCATCCG CTACATGGCT 1140

CCAGAGGTGC TGGAGGGGGC GGTGAACCTG AGGGACTGTG AGTCTGCCCT GAAGCAGGTG 1200

GATATGTACG CTCTGGGCCT GCTCTACTGG GAGACCTTCA TGAGGTGCAC TGACCTTTTC 1260

CCAGGAGAGG CCGTGCCAGA GTACCAGATG GCCTTCCAGG CAGAGACAGA GGCAGGGAAC 1320

CACCCCACAT TTGAGGATAT GCAGGTCCTT GTATCCAGAG AGAAGCAACG GCCCAAATTC 1380

CCAGAGGCCT GGAAAGAGAA CAGTTTGGCG GTGCGCTCTC TAAAAGAGAC GATGGAGGAC 1440

TGCTGGGACC AGGATGCAGA GGCCCGCCTC ACGGCTCAGT GTGCCGAGGA GCGTCTCGCA 1500

GAGCTGCTCC TCATATGGGA CCGATCCAAG TCCGTCAGCC CCACGCTTAA CCCCATGTCC 1560

ACCACCCTGC ACAATGAAAG GTGGACACCA ACATGCAACA CTTGG 1605

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         lkllelig+Gryg+V+ ++l+++ vAvK+f++++++++ +E  iy+++ll+h+ni +f+a

Q: 199   LKLLELIGRGRYGTVYCGSLDERPVAVKVFTATNRQNFLNECSIYRLPLLEHDNIARFVA  258

         6899********************************************************

S: 61    adk.keedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgt  119

         ad+ + ++ +te+llv+ey+++gsL  yL+ +t d+ +++rla+s+++Gla+LH+e+++

Q: 259   ADErTGSEGRTEYLLVMEYYPHGSLNRYLSVQTNDWVSSCRLAHSVTRGLAYLHTELFKG  318

         ***9999*************************************************8755

S: 120   kgkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekee....ldlaansqvGtkR  175

          + +Kpa++HRDl+s+N+lvk d+tc+i D+GL++kl+ ++ +    +++aa+s+vGt R

Q: 319   -DLYKPAVSHRDLNSRNVLVKADGTCVIIDFGLSMKLTGNRPArhgeEENAAISEVGTIR  377

         .57**********************************999887777788899********

S: 176   YmaPEvleealnlkdfe.afkraDvYslgLvlWEvasRcee..vdeeveeyklpfeevv.  231

         YmaPEvle+a+nl+d+e a+k++D+Y+lgL++WE ++Rc++  ++e+v+ey+++f+++

Q: 378   YMAPEVLEGAVNLRDCEsALKQVDMYALGLLYWETFMRCTDlfPGEAVPEYQMAFQAETe  437

         *****************99************************************87652

S: 232   .gsdPsleemkevvvekklrPkipeawkkke.alkelsklleecWdadpeaRltalrvkk  289

          g++P++e+m+ +v ++k+rPk+peawk+++ a+++l++++e+cWd+d+eaRlta++ ++

Q: 438   aGNHPTFEDMQVLVSREKQRPKFPEAWKENSlAVRSLKETMEDCWDQDAEARLTAQCAEE  497

         279**************************9999*************************99

S: 290   rl  291

rl

Q: 498   RL  499

Domain Sequence
(FASTA)

LKLLELIGRG RYGTVYCGSL DERPVAVKVF TATNRQNFLN ECSIYRLPLL EHDNIARFVA 60

ADERTGSEGR TEYLLVMEYY PHGSLNRYLS VQTNDWVSSC RLAHSVTRGL AYLHTELFKG 120

DLYKPAVSHR DLNSRNVLVK ADGTCVIIDF GLSMKLTGNR PARHGEEENA AISEVGTIRY 180

MAPEVLEGAV NLRDCESALK QVDMYALGLL YWETFMRCTD LFPGEAVPEY QMAFQAETEA 240

GNHPTFEDMQ VLVSREKQRP KFPEAWKENS LAVRSLKETM EDCWDQDAEA RLTAQCAEER 300

L 301

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR015770	; BMPRII.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013