EKS-TAR-00584

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00584

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	375.3	4.2E-112	61	347	287

Status

Unreviewed

Ensembl Protein

ENSTRUP00000016238

UniProt Accession

H2SUZ9;

Protein Name

Protein Synonyms/Alias

Gene Name

Tru.1854

Gene Synonyms/Alias

Tru.1854;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000006607	ENSTRUP00000016238	ENSTRUT00000016310
ENSTRUG00000006607	ENSTRUP00000016237	ENSTRUT00000016309

Organism

Takifugu rubripes

Functional Description

Protein Length

447

Protein Sequence
(FASTA)

MAAYNGGSSA VAAHHPHHHH QLQHLPPPHM HHHHHHLQHP GSAAAQHQQH HLQQQLDIEP 60

DRPIGYGAFG VVWSVTDPRD GKRVALKKMP NVFQNLVSCK RVFRELKMLC FFKHENVLSA 120

LDMLQPPHID YFEEIYVVTE LMQSDLHKII VSPQPLSSDH AKVFLYQILR GLKYLHSAGI 180

LHRDIKPGNL LVNSNCVLKI CDFGLARVEE SDEARHMTQE VVTQYYRAPE ILMGSRHYSN 240

SIDIWSVGCI FAELLGRRIL FQAQSPIQQL DLITDLLGTP SMEAMRTACE GARAHILRGP 300

HKQPSLPVLY TLSSQATHEA VHLLCRMLVF DPSKRISAKD ALAHPYLDEG RLRYHTCMCK 360

CCYTTSSGRV YTSDFEPVTN PKFDDGFEKN LSSVRQVKEI IHQFILEQQK GSRVPLCINP 420

QSAAFKSFIS STVAQPSEMP PSPLVWE 447

Nucleotide Sequence
(FASTA)

ATGGCTGCGT ACAACGGAGG CTCCTCGGCC GTGGCCGCTC ACCACCCGCA CCACCACCAC 60

CAGCTGCAGC ACCTGCCGCC CCCCCACATG CACCACCACC ACCACCACCT GCAGCACCCG 120

GGCTCCGCCG CCGCCCAGCA CCAGCAGCAC CACCTCCAGC AGCAGCTGGA CATCGAGCCC 180

GACAGGCCCA TCGGATACGG AGCGTTCGGG GTGGTCTGGT CGGTGACGGA CCCCCGAGAC 240

GGGAAGCGAG TCGCTCTCAA AAAGATGCCC AACGTCTTCC AAAACCTTGT TTCTTGTAAG 300

AGGGTGTTCC GGGAGCTGAA AATGCTCTGC TTCTTCAAAC ATGAAAACGT TCTCTCGGCT 360

CTGGACATGC TACAACCGCC ACACATCGAC TACTTTGAGG AAATCTACGT GGTCACAGAA 420

CTGATGCAAA GCGACCTCCA TAAGATCATC GTGTCTCCGC AGCCACTGAG CTCCGACCAC 480

GCCAAAGTCT TTCTCTACCA GATTCTGCGA GGACTCAAGT ACCTTCACTC TGCCGGCATC 540

CTGCACCGGG ACATCAAGCC AGGGAACCTG CTGGTCAACA GCAACTGTGT GCTGAAGATC 600

TGCGACTTCG GCCTGGCTCG GGTGGAGGAG TCGGACGAGG CGCGGCACAT GACCCAGGAA 660

GTGGTGACGC AGTACTACCG GGCGCCGGAG ATCCTCATGG GGAGCCGCCA CTACTCCAAC 720

TCCATCGACA TCTGGTCTGT AGGCTGCATC TTCGCAGAGC TGCTGGGCCG TCGCATCCTC 780

TTCCAAGCCC AGAGTCCCAT CCAGCAGCTT GACCTGATCA CTGACCTGCT GGGGACGCCG 840

TCGATGGAAG CCATGAGGAC GGCGTGCGAA GGCGCCCGAG CGCACATTCT CAGAGGGCCC 900

CACAAGCAGC CATCACTTCC TGTTCTGTAC ACGCTGTCTA GCCAAGCGAC CCATGAAGCG 960

GTCCACCTCC TCTGCAGGAT GCTGGTGTTC GATCCGTCCA AGCGGATTTC GGCGAAGGAC 1020

GCCCTGGCTC ACCCCTACCT GGACGAGGGC CGCCTGCGCT ACCACACCTG CATGTGTAAA 1080

TGCTGCTACA CCACGTCCTC CGGACGCGTC TACACCAGTG ACTTTGAGCC CGTCACCAAC 1140

CCCAAGTTCG ACGACGGCTT TGAGAAGAAC CTCAGCTCTG TGAGACAGGT CAAAGAAATC 1200

ATCCATCAGT TCATTCTGGA ACAGCAAAAA GGGAGCCGAG TTCCTCTCTG CATCAACCCT 1260

CAATCAGCAG CTTTTAAGAG CTTCATCAGT TCCACAGTGG CGCAGCCGTC TGAAATGCCT 1320

CCATCTCCGC TGGTGTGGGA GTAG 1344

Domain Profile

S: 4     lkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNiikl  63

          +p+g Ga+gvv+s++d r+++rva+kk+ ++fq+ +s+kr++RElk+l  +kheN+++

Q: 61    DRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHENVLSA  120

         689*********************************************************

S: 64    ldvftpeeeleelkdvYlvtelmetdLkkviksq.klsdehiklllyqilrglkylHsan  122

         ld+++p + ++ ++++Y+vtelm++dL+k+i s   ls++h+k++lyqilrglkylHsa+

Q: 121   LDMLQPPH-IDYFEEIYVVTELMQSDLHKIIVSPqPLSSDHAKVFLYQILRGLKYLHSAG  179

         *******9.**********************99879************************

S: 123   viHrDlKPsNllvnedcelkildFGlarsadkekekklteyvatrwYraPeillslkeyt  182

         ++HrD+KP+Nllvn++c lki+dFGlar++++++ +++t++v+t++YraPeil+ +++y+

Q: 180   ILHRDIKPGNLLVNSNCVLKICDFGLARVEESDEARHMTQEVVTQYYRAPEILMGSRHYS  239

         ************************************************************

S: 183   kavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkieseearnyiks  242

         +++DiWsvGCI+aEll +++lf++++ i+ql++i+++lgtps e +++ ++  ar++i +

Q: 240   NSIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSMEAMRTACEG-ARAHILR  298

         ************************************************9996.8888888

S: 243   lpkkkkk..dfeelfpkaseealdLleklLvldpdkRisveeaLehpYl  289

          p+k+     + +l ++a++ea++Ll ++Lv+dp+kRis+++aL+hpYl

Q: 299   GPHKQPSlpVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYL  347

         87776654467788888*******************************7

Domain Sequence
(FASTA)

DRPIGYGAFG VVWSVTDPRD GKRVALKKMP NVFQNLVSCK RVFRELKMLC FFKHENVLSA 60

LDMLQPPHID YFEEIYVVTE LMQSDLHKII VSPQPLSSDH AKVFLYQILR GLKYLHSAGI 120

LHRDIKPGNL LVNSNCVLKI CDFGLARVEE SDEARHMTQE VVTQYYRAPE ILMGSRHYSN 180

SIDIWSVGCI FAELLGRRIL FQAQSPIQQL DLITDLLGTP SMEAMRTACE GARAHILRGP 240

HKQPSLPVLY TLSSQATHEA VHLLCRMLVF DPSKRISAKD ALAHPYL 287

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004707	; F:MAP kinase activity
GO:0000165	; P:MAPK cascade

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR003527	; MAP_kinase_CS.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS01351	; MAPK; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013